# overview
Our research interest is to design methods for the genetic incorporation of noncanonical amino acids into proteins in living cells and apply these methods in three major directions: deciphering functions of protein posttranslational modifications, small molecule sensing, and expanding chemical diversities of phage display libraries. To study protein posttranslational modifications, we have constructed methods for the site-specific installation of lysine acetylation and methylation in proteins and will apply them to study functional roles of these two modifications on p53, a tumor suppressor protein. We have also developed a strategy to site-specifically install two noncanonical amino acids into one protein in E. coli and are applying this approach to construct biosensors for small organic molecules and metal ions. Phage display is an efficient method to identify peptides for therapeutic interventions. However, a phage display peptide library has limited structure motifs and functional groups because only 20 natural amino acids can be used to generate a library. We plan to expand the chemical diversity of a phage display library by incorporating multiple noncanonical amino acids and chemically modifying them to extend functional diversities. Screening this unnatural phage display library against therapeutic targets such as c-Abl tyrosine kinase is expected to identify highly potent inhibitors.

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
United States Food And Drug Administration

# keywords[]
3404 Medicinal And Biomolecular Chemistry

# keywords[]
3404 Medicinal And Biomolecular Chemistry

# keywords[]
3403 Macromolecular And Materials Chemistry

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
3404 Medicinal And Biomolecular Chemistry

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# educationAndTraining[].organization.label
University of California, Davis - (Davis, California, United States)

# educationAndTraining[].organization.label
Beijing University of Technology - (Beijing, Beijing, China)

# awardsAndHonors[].label
Faculty Early Career Development (CAREER) Program

# publications[].label
A Genetically Encoded BoronateContaining Amino Acid

# publications[].label
Expressed Protein Ligation without Intein.

# publications[].label
A facile system for genetic incorporation of two different noncanonical amino acids into one protein in Escherichia coli.

# publications[].label
Reversal of the hofmeister series: specific ion effects on peptides.

# publications[].label
Role of Q52 in catalysis of decarboxylation and transamination in dialkylglycine decarboxylase.

# publications[].label
Structural basis for the recognition of para-benzoyl-L-phenylalanine by evolved aminoacyl-tRNA synthetases.

# publications[].label
Chemical biology approach for dimethyllysine incorporation into proteins

# publications[].label
Facile system for genetic incorporation of two different noncanonical amino acids into one protein in Escherichia coli

# publications[].label
The nitrilimine-alkene cycloaddition is an ultra rapid click reaction.

# publications[].label
Cover Picture: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. Int. Ed. 10/2022)

# publications[].label
A Recurring Chemogenetic Switch for Chimeric Antigen Receptor T Cells

# publications[].label
Near-cognate suppression of amber, opal and quadruplet codons competes with aminoacyl-tRNAPyl for genetic code expansion.

# publications[].label
Site specific protein labeling of genetically encoded strained alkene/alkyne functionalities in vivo via rapid catalyst-free click chemistry

# publications[].label
An optimal "Click" formulation strategy for antibody-drug conjugate synthesis.

# publications[].label
Probing the catalytic charge relay system in alanine racemase enzyme with genetically encoded histidine mimetics

# publications[].label
A Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2

# publications[].label
A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.

# publications[].label
Nonsense and sense suppression abilities of original and derivative Methanosarcina mazei pyrrolysyl-tRNA synthetase-tRNA(Pyl) pairs in the Escherichia coli BL21(DE3) cell strain.

# publications[].label
Protein Synthesis via Activated Cysteine-Directed Protein Ligation.

# publications[].label
A Versatile Approach for Site-Specific Lysine Acylation in Proteins.

# publications[].label
Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease.

# publications[].label
The Effects of Site Specific Histone Modifications on Nucleosomal DNA Accessibility

# publications[].label
Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1.

# publications[].label
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes.

# publications[].label
An Enhanced Hybrid Screening Approach to Identify Potent Inhibitors for the SARS-CoV-2 Main Protease From the NCI Compound Library.

# publications[].label
Effects of End Group Termination on Salting-Out Constants for Triglycine.

# publications[].label
Genetic incorporation of an aliphatic keto-containing amino acid into proteins for their site-specific modifications.

# publications[].label
MPI8 is Potent against SARS-CoV-2 by Inhibiting Dually and Selectively the SARS-CoV-2 Main Protease and the Host Cathepsin L.

# publications[].label
E1-catalyzed ubiquitin C-terminal amidation for the facile synthesis of deubiquitinase substrates.

# publications[].label
Drug Repurposing for the SARS-CoV-2 Papain-Like Protease.

# publications[].label
Sirtuins 1 and 2 Are Universal Histone Deacetylases.

# publications[].label
RESVERATROL BINDS NUCLEAR RECEPTOR 4A1 (NR4A1) AND ACTS AS AN NR4A1 ANTAGONIST IN LUNG CANCER CELLS.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
A Click Chemistry Approach to Reveal the chromatin-Dependent Histone H3 K36 Deacetylase Nature of SIRT7

# publications[].label
Genetic incorporation of unnatural amino acids into proteins in mammalian cells.

# publications[].label
Repurposing Halicin as a Potent Covalent Inhibitor for the SARS-CoV-2 Main Protease

# publications[].label
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals.

# publications[].label
Genetic code expansion: Synthetases pick up the PACE.

# publications[].label
The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives.

# publications[].label
A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7.

# publications[].label
A click chemistry approach to site-specific immobilization of a small laccase enables efficient direct electron transfer in a biocathode.

# publications[].label
A Genetically Encoded Allysine for the Synthesis of Proteins with SiteSpecific Lysine Dimethylation

# publications[].label
Kinetic and crystallographic analysis of active site mutants of Escherichia coli gamma-aminobutyrate aminotransferase.

# publications[].label
Evolving the N-Terminal Domain of Pyrrolysyl-tRNA Synthetase for Improved Incorporation of Noncanonical Amino Acids.

# publications[].label
Probing the active site of alanine racemase by incorporation of non-canonical amino acids

# publications[].label
Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2.

# publications[].label
Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.

# publications[].label
The genetic incorporation of thirteen novel non-canonical amino acids.

# publications[].label
Front Cover: Evolving the NTerminal Domain of PyrrolysyltRNA Synthetase for Improved Incorporation of Noncanonical Amino Acids (ChemBioChem 1/2018)

# publications[].label
Reports from the Chemical Biology of Texas Symposium at the 69th Southwest Regional Meeting of the American Chemical Society.

# publications[].label
Catalyst-free and site-specific one-pot dual-labeling of a protein directed by two genetically incorporated noncanonical amino acids.

# publications[].label
Expanding the chemical diversity of lasso peptide MccJ25 with genetically encoded noncanonical amino acids.

# publications[].label
Titelbild: A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells (Angew. Chem. 10/2022)

# publications[].label
A Reversible Chemogenetic Switch for Chimeric Antigen Receptor TCells.

# publications[].label
The Construction of a Genetically Encoded, Phage-Displayed Cyclic-Peptide Library.

# publications[].label
Engineering the N-terminal domain of pyrrolysyl-tRNA synthetase: Optimizing genetic incorporation of non-canonical amino acids

# publications[].label
Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.

# publications[].label
Drug Repurposing for the SARS-CoV-2 Papain-Like Protease

# publications[].label
A genetically encoded aldehyde for rapid protein labelling.

# publications[].label
Frontispiece: Proteins with SiteSpecific Lysine Methylation

# publications[].label
Facile Removal of Leader Peptides from Lanthipeptides by Incorporation of a Hydroxy Acid.

# publications[].label
Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV.

# publications[].label
Nitrilimine-alkene cycloaddition as an ultra rapid click reaction for protein labeling

# publications[].label
A Genetically Encoded Allysine for the Synthesis of Proteins with Site-Specific Lysine Dimethylation.

# publications[].label
Probing the Catalytic Charge-Relay System in Alanine Racemase with Genetically Encoded Histidine Mimetics.

# publications[].label
Expressed Protein Ligation Without Intein

# publications[].label
Phage-Assisted, Active Site-Directed Ligand Evolution with a Genetically Encoded N-Butyryl-L-Lysine to Identify a Cellularly Potent and Selective Inhibitor for the ENL YEATS Domain as an Anti-Leukemia Agent

# publications[].label
Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.

# publications[].label
Alternative codon study for genetic code expansion in Escherichia coli

# publications[].label
Genetic incorporation of a benzaldehyde residue for rapid bioorthogonal labeling at neutral pH

# publications[].label
Cover Feature: Covalent Inhibition in Drug Discovery (ChemMedChem 9/2019)

# publications[].label
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease.

# publications[].label
E1-catalyzed ubiquitin C-terminal amidation for the facile syntheses of deubiquitinase substrates

# publications[].label
Site Specific Lysine Acetylation of Histones for Nucleosome Reconstitution using Genetic Code Expansion in Escherichia coli.

# publications[].label
A genetically encoded boronate-containing amino acid.

# publications[].label
Site specific post-translational modifications of protein by expanding the genetic code: Protein methylation and structure enrichment

# publications[].label
Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition.

# publications[].label
Manipulating protein pi-pi interactions by site-specific incorporation of fluorinated phenylalanine analogs

# publications[].label
Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid.

# publications[].label
Pyrrolysyl-tRNA synthetase: An ordinary enzyme but an outstanding genetic code expansion tool

# publications[].label
A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems.

# publications[].label
Synthesis of proteins with defined posttranslational modifications using the genetic noncanonical amino acid incorporation approach.

# publications[].label
A Designed, Highly Efficient Pyrrolysyl-tRNA Synthetase Mutant Binds o-Chlorophenylalanine Using Two Halogen Bonds.

# publications[].label
tRNAPyl: Structure, function, and applications.

# publications[].label
A Versatile Approach for SiteSpecific Lysine Acylation in Proteins

# publications[].label
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes (vol 50, pg 13085, 2014)

# publications[].label
Bepridil is potent against SARS-CoV-2 In Vitro.

# publications[].label
Genetic encoding of methyl- and acetyl-lysine analogs into proteins

# publications[].label
Structural insights into the -- stacking mechanism and DNA-binding activity of the YEATS domain.

# publications[].label
Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay.

# publications[].label
A facile method to synthesize histones with posttranslational modification mimics.

# publications[].label
Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader.

# publications[].label
A Genetically Encoded Bidentate, MetalBinding Amino Acid

# publications[].label
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.

# publications[].label
Stepwise Assembly of Turn-on Fluorescence Sensors in Multicomponent Metal-Organic Frameworks for inVitro Cyanide Detection.

# publications[].label
Accurate Mass Identification of an Interfering Water Adduct and Strategies in Development and Validation of an LC-MS/MS Method for Quantification of MPI8, a Potent SARS-CoV-2 Main Protease Inhibitor, in Rat Plasma in Pharmacokinetic Studies.

# publications[].label
A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease.

# publications[].label
Front Cover: MPI8 is Potent against SARSCoV2 by Inhibiting Dually and Selectively the SARSCoV2 Main Protease and the Host Cathepsin L (ChemMedChem 1/2022)

# publications[].label
Fluorinated Aromatic Amino Acids Distinguish Cation- Interactions from Membrane Insertion.

# publications[].label
Deacetylase substrate specificity analysis: Decoding the histone language

# publications[].label
Bepridil is potent against SARS-CoV-2 in vitro.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Systematic studies of nonsense suppression abilities of Methanosarcina mazei pyrrolysyl-tRNA synthetase-tRNA(Pyl) pair in Escherichia coli

# publications[].label
Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.

# publications[].label
A convenient method for genetic incorporation of multiple noncanonical amino acids into one protein in Escherichia coli.

# publications[].label
Stepwise Assembly of Turnon Fluorescence Sensors in Multicomponent MetalOrganic Frameworks for in Vitro Cyanide Detection

# publications[].label
Using Amber and Ochre Nonsense Codons to Code Two Different Noncanonical Amino Acids in One Protein Gene.

# publications[].label
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases.

# publications[].label
Genetic incorporation of twelve meta-substituted phenylalanine derivatives using a single pyrrolysyl-tRNA synthetase mutant.

# publications[].label
Towards reassigning the rare AGG codon in Escherichia coli.

# publications[].label
Genetically encoded acrylamide functionality directs diverse bioorthogonal protein modifications

# publications[].label
A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease

# publications[].label
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals.

# publications[].label
Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019-nCoV.

# publications[].label
Genetic incorporation of unnatural amino acids into proteins in mammalian cells

# publications[].label
Improving the bioactivity of rHirudin with boronophenylalanine site-specific modification.

# publications[].label
An amber obligate active site-directed ligand evolution technique for phage display.

# publications[].label
A Reversible Chemogenetic Switch for Chimeric Antigen Receptor T Cells**

# publications[].label
A genetically encoded acrylamide functionality.

# publications[].label
A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum.

# publications[].label
Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain.

# publications[].label
Increasing insulin yield by fusion with superfolder green fluorescing protein

# publications[].label
The "-Clamp" Offers a New Strategy for Site-Selective Protein Modification.

# publications[].label
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.

# publications[].label
Proteins with Site-Specific Lysine Methylation.

# publications[].label
A Genetically Encoded, PhageDisplayed CyclicPeptide Library

# publications[].label
Zinc thiotropolone combinations as inhibitors of the SARS-CoV-2 main protease.

# publications[].label
BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease.

# publications[].label
Kinetic and thermodynamic analysis of the interaction of cations with dialkylglycine decarboxylase.

# publications[].label
An amber-encoding helper phage for more efficient phage display of noncanonical amino acids.

# publications[].label
A genetically encoded diazirine photocrosslinker in Escherichia coli.

# publications[].label
Selecting folded proteins from a library of secondary structural elements.

# publications[].label
Structural Basis for the Recognition of paraBenzoylLphenylalanine by Evolved AminoacyltRNA Synthetases

# publications[].label
Phage-assisted, active site-directed ligand evolution of a potent and selective histone deacetylase 8 inhibitor.

# publications[].label
Incorporation of Nonproteinogenic Amino Acids in Class I and II Lantibiotics.

# publications[].label
Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors

# publications[].label
Phospha-Michael Addition as a New Click Reaction for Protein Functionalization.

# publications[].label
Sirtuin 2 inhibitors identified by phage display with an expanded genetic code

# publications[].label
A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes.

# publications[].label
The Pyrrolysyl-tRNA Synthetase Activity can be Improved by a P188 Mutation that Stabilizes the Full-Length Enzyme.

# publications[].label
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.

# publications[].label
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors.

# publications[].label
A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors.

# publications[].label
Corrigendum: Drug Repurposing for the SARS-CoV-2 Papain-Like Protease.

# publications[].label
Phage-Assisted, Active Site-Directed Ligand Evolution of a Potent and Selective Histone Deacetylase 8 Inhibitor

# publications[].label
Evolutionary and Structural Insights about Potential SARS-CoV-2 Evasion of Nirmatrelvir.

# publications[].label
MPI8 is Potent Against SARS-CoV-2 by Inhibiting Dually and Selectively the SARS-CoV-2 Main Protease and the Host Cathepsin L

# publications[].label
Novel luminescence-based assay for deubiquitinases inhibitors discovery

# publications[].label
Cellular Activities of SARS-CoV-2 Main Protease Inhibitors Reveal Their Unique Characteristics

# publications[].label
A genetically encoded bidentate, metal-binding amino acid.

# publications[].label
The molecular basis of tight nuclear tethering and inactivation of cGAS.

# researcherOn[].label
The Preparation of Novel Phage-Displayed Macrocyclic Peptide Libraries for the Identification of Anticancer Agents

# researcherOn[].awardedBy.label
Cancer Prevention and Research Institute of Texas - (Austin, Texas, United States)

# researcherOn[].label
Develop General Methods for the Synthesis of Proteins with Posttranslational Lysine Modifications

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of General Medical Science

# researcherOn[].label
Career: Site-Specific Dual-Labeling of A Protein Through Two Genetically Incorporated Noncanonical Amino Acids

# researcherOn[].awardedBy.label
National Science Foundation - (Arlington, Virginia, United States)

# researcherOn[].label
Studying Reversible Histone Acylations in Nucleosome Contexts

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of General Medical Science

# researcherOn[].label
Phage Display With Two Genetically Incorporated Noncanonical Amino Acids

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# streetAddress
Texas A&M University; Chemistry Department; 3255 TAMU

# inTheNews[].label
Texas A&M chemists working on drugs to treat COVID-19

# inTheNews[].label
Chemist Remains Optimistic About Succes of Antiviral in Treating COVID-19

# inTheNews[].label
The US spent a lot of money on Remdesivir. What is it?

# inTheNews[].label
The federal government shipped remdesivir to hospitals this week, but North Texas received none

# inTheNews[].label
Texas A&M researchers are working on multiple new drugs to fight COVID-19

# inTheNews[].label
Novel phage display technique could lead to new therapeutics

# inTheNews[].label
How known drugs could be applied to the current coronavirus outbreak

# inTheNews[].label
TAMU researchers say potential COVID-19 treatment could be a 'gamechanger'

# inTheNews[].label
Paving the way for new peptide-based therapeutics with novel method of phage display

# inTheNews[].label
Texas A&M scientist discovers first COVID-19 treatment drug

# inTheNews[].label
Lessons from a cancer diagnosis, and what it teaches us about surviving the COVID-19 pandemic

# inTheNews[].label
The Molecular Basis of Tight Nuclear Tethering and Inactivation of CGAS

# inTheNews[].label
New 'genetic code' coronavirus vaccine in the works

# inTheNews[].label
X-Grants Program Provides Funding for Eight Interdisciplinary Projects

# inTheNews[].label
Texas A&M professor identified COVID-19 treatment now used in Texas hospitals

# etdChairOf[].label
Wu, Bo (2014-06). Synthesis of Proteins with Homogenous Chemical and Posttranslational Modifications. Doctoral Dissertation.

# etdChairOf[].label
Wang, Xiaoshan (2018-04). The Nitrilimine-Alkene Cycloaddition Mechanism and Phage-displayed Cyclic Peptide Libraries for Drug Discovery. Doctoral Dissertation.

# etdChairOf[].label
Deonarine-Chihak, Sasha Mala (2016-08). A Tetrazine-Terminal Alkene System for Profiling Protein Fatty Acylation Modifications. Master's Thesis.

# etdChairOf[].label
Lee, Yan-Jiun (2015-12). Expanding the Genetic Code for Synthesis of Proteins with Native Biological Modifications and Novel Chemical, Biophysical Probes. Doctoral Dissertation.

# etdChairOf[].label
Wang, Zhipeng (2018-04). The Chemical Synthetic Investigation of Proteins with Sitespecific Lysine Post-Translational Modifications. Doctoral Dissertation.

# etdChairOf[].label
Sharma, Vangmayee (2017-07). The Engineering and Optimization of Pyrrolysyl-Synthetase as a Tool for Noncanonical Amino Acid Incorporation. Doctoral Dissertation.

# etdChairOf[].label
Odoi, Keturah Amarkie (2016-10). Protein Engineering: Amending Proteins with Chemical Functionalities. Doctoral Dissertation.

# etdChairOf[].label
Odoi, Keturah (2012-07). Orthogonality and Codon Preference of the Pyrrolysyl-tRNA Synthetase-tRNAPyl pair in Escherichia coli for the Genetic Code Expansion. Master's Thesis.

# etdChairOf[].label
Huang, Ying (2012-07). Genetic Incorporation of Noncanonical Amino Acids into Proteins for Protein Function Investigation. Doctoral Dissertation.

# etdChairOf[].label
Hsu, Willie Weili (2017-07). The Investigation of Sirtuin Activities on Short-Chained Mono-Acylated Histone H3 Tetramers and Nucleosomes. Doctoral Dissertation.