# positions[].organizations[].parent[].label
School of Education and Human Development

# overview
My research focuses on on the genetics of daily physical activity and exercise endurance, as well as the physiological response to high-G exposure and hemorrhage, and the genetics of physical activity.  My lab also has a unique interest in the physiological responses of athletes in a variety of non-traditional venues such as auto racing and in musicians.

# keywords[]
6 Evaluation Of Treatments And Therapeutic Interventions

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Dopamine Plasma Membrane Transport Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# educationAndTraining[].organization.label
University of Tennessee at Knoxville - (Knoxville, Tennessee, United States)

# publications[].label
Why control activity? Evolutionary selection pressures affecting the development of physical activity genetic and biological regulation.

# publications[].label
Association Between Mitochondrial Dna Sequence, Heteroplasmy, And Indels With Response To Aerobic Exercise Training

# publications[].label
Effects of Aromatase Inhibition on the Physical Activity Levels of Male Mice.

# publications[].label
Characterization Of Mitochondrial Genome Indels In Individuals Classified By High And Low Vo(2max) Trainability

# publications[].label
Influence of genetic background on daily running-wheel activity differs with aging.

# publications[].label
Current understanding of the genetic basis for physical activity.

# publications[].label
A High Fat/High Sugar Diet Alters the Gastrointestinal Metabolome in a Sex Dependent Manner.

# publications[].label
Commentary on viewpoint: Perspective on the future use of genomics in exercise prescription.

# publications[].label
Quantification of tolerance to lower body negative pressure in a healthy population.

# publications[].label
Vivo-morpholinos induced transient knockdown of physical activity related proteins.

# publications[].label
Afterword  closing the loop: Observations and conclusions

# publications[].label
Epistatic interactions of genes influence within-individual variation of physical activity traits in mice.

# publications[].label
Metabolic Differences in Nonessential Amino Acid Plasma Concentrations in High- and Low-Active Mice

# publications[].label
Strain Screen Suggests Genetic Influence on Physical Activity Varies Across the Lifespan

# publications[].label
Alleles Associated with Voluntary Physical Activity are Predicted to be Older Than Anatomically Modern Humans

# publications[].label
Can You Be Born a Couch Potato? The Genomic Regulation of Physical Activity

# publications[].label
Altered dopaminergic profiles: implications for the regulation of voluntary physical activity.

# publications[].label
High Fat High Sugar Diet Reduces Voluntary Wheel Running in Mice Independent of Sex Hormone Involvement.

# publications[].label
Influence of age of exposure to a running wheel on activity in inbred mice.

# publications[].label
Comparison of Neurocognitive Testing and the Measurement of Marinobufagenin in Mild Traumatic Brain Injury: A Preliminary Report.

# publications[].label
Promoting the STEM Pipeline and Enhancing STEM Career Awareness Through Participation in Authentic Research Activities (RTP, Diversity)

# publications[].publisher
American Society for Engineering Education

# publications[].label
The Effect Of A High Fat/high Sugar Diet And Physical Activity On Body Fat Percentage And Bone Mineral Density

# publications[].label
Pharmacological manipulation of the dopaminergic system affects wheel-running activity in differentially active mice.

# publications[].label
Resistance training increases lower body negative pressure tolerance.

# publications[].label
EFFECTS OF DIET ALTERATIONS, WITH OR WITHOUT FECAL MICROBIAL TRANSPLANTS, ON BONE INTEGRITY

# publications[].label
Effect of High Fat/High Sugar Diet & Physical Activity on Sex Hormone Concentrations

# publications[].label
Reproducibility of resting heart rate variability with short sampling periods.

# publications[].label
Heart rate and core temperature responses of elite pit crews during automobile races.

# publications[].label
Systems Exercise Genetics Research Design Standards.

# publications[].label
Dopaminergic Receptor and Transporter Densities in Nucleus Accumbens Are Not Altered by a Western Diet

# publications[].label
Knock-down of Vmat2 in Mouse Right Striatum and Physical Activity

# publications[].label
The effects of breathing 5% CO2 on human cardiovascular responses and tolerance to orthostatic stress.

# publications[].label
Heart Rate Response of Professional Musicians When Playing Music.

# publications[].label
Differential miRNA expression in inherently high- and low-active inbred mice.

# publications[].label
Can blood pressure be measured during exercise? A review.

# publications[].label
Potential Wash-out of Vmat2 Gene Silencing by Exercise Exposure

# publications[].label
Physical activity and food consumption in high- and low-active inbred mouse strains.

# publications[].label
Mitochondrial DNA lesions and copy number are strain dependent in endurance-trained mice.

# publications[].label
A search for quantitative trait loci controlling within-individual variation of physical activity traits in mice.

# publications[].label
A different method of teaching peer review systems.

# publications[].label
Reduced Wheel Running via a High-Fat Diet Is Reversed by a Chow Diet with No Added Benefit from Fecal Microbial Transplants.

# publications[].label
The effects of isometric exercise training on resting blood pressure and orthostatic tolerance in humans.

# publications[].label
7,12-dimethylbenz(a)-anthracene (DMBA) & High Fat High Sugar Diet Decrease Physical Activity in Female Mice

# publications[].label
Ambient noise interferes with auscultatory blood pressure measurement during exercise.

# publications[].label
The effect of vivo-Morpholinos on Dopamine Receptor 1 (Drd1) and physical activity in mice

# publications[].label
High-active Mice Have Elevated Clearance Rate Of Bcaas Compared To Low-active Mice

# publications[].label
Comparable Organ Protein Fractional Synthesis Rate of High and Low-Active Mice

# publications[].label
Chicken and the Egg: Physical Activity and Epigenetics.

# publications[].label
A Ketogenic Diet In Mice Reduces Cardiac Protein Synthesis Compared to a Western Diet

# publications[].label
Exercise biology and medicine: innovative research to improve global health.

# publications[].label
Occurrence of presyncope in subjects without ventricular innervation.

# publications[].label
A wide range of baroreflex stimulation does not alter forearm blood flow.

# publications[].label
Two Dimensional Differential Gel Electrophoresis Analysis of the Nucleus accumbens in High and Low Active Mice

# publications[].label
Genetic variation for body weight change in mice in response to physical exercise.

# publications[].label
Cardiovascular responses to lower body negative pressure in trained and untrained older men.

# publications[].label
Differential gene expression in high- and low-active inbred mice.

# publications[].label
Physical Activity Impacts of an Activity-Friendly Community: A Natural Experiment Study Protocol.

# publications[].label
Acute Exposure to a High-Fat High-Sugar Diet Alters Wheel Running Activity

# publications[].label
Quantitative trait loci for physical activity traits in mice.

# publications[].label
Quantitative trait loci associated with maximal exercise endurance in mice.

# publications[].label
Does the difference between physically active and couch potato lie in the dopamine system?

# publications[].label
The effect of Vivo-Morpholino targeting Vmat2 on daily physical activity in mouse soleus compared to scrambled-morpholino control

# publications[].label
The Effect of a High Fat/High Sugar Diet on Physical Activity in Female Mice

# publications[].label
Genetic Epidemiology, Physical Activity, and Inactivity

# publications[].label
The Regulation of Physical Activity by Genetic Mechanisms: Is there a Drive to be Active?

# publications[].label
Expression Of Tyrosine Hydroxylase In The Nucleus Accumbens Are Not Altered By Diet Or Fecal Transplantation In Male C57bl/6j Mice

# publications[].label
The Importance Of Accurate Measurements In Voluntary Wheel Running In Mice

# publications[].label
Immediate Postexercise Massage Does Not Attenuate Delayed Onset Muscle Soreness.

# publications[].label
Repeatability of exercise behaviors in mice.

# publications[].label
Driven to be inactive? The genetics of physical activity.

# publications[].label
Differential skeletal muscle proteome of high- and low-active mice.

# publications[].label
Naloxone decreases tolerance to hypotensive, hypovolemic stress healthy humans.

# publications[].label
Optimizing the Physical Conditioning of the NASCAR Sprint Cup Pit Crew Athlete

# publications[].label
Postnatal wheel running mitigates endocrine disruption of mammary gland development in mice

# publications[].label
Genetic influence on daily wheel running activity level.

# publications[].label
The evolution of genetic mechanisms controlling physical activity

# publications[].label
Biological/Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC.

# publications[].label
Automated blood pressure measurements during exercise.

# publications[].label
Activated whole-body arginine pathway in high-active mice.

# publications[].label
Lessons learned from vivo-morpholinos: How to avoid vivo-morpholino toxicity.

# publications[].label
Ten weeks of aerobic training do not affect lower body negative pressure responses.

# publications[].label
Presyncope caused by central hypovolaemia is not preceded by evoked potential alterations.

# publications[].label
Optimizing the physical conditioning of the NASCAR sprint cup pit crew athlete.

# publications[].label
Protein fractional synthesis rates within tissues of high- and low-active mice.

# publications[].label
Sibling Resemblances in Physical Fitness in Three Distinct Regions in Peru: The Peruvian Sibling Study on Growth and Health.

# publications[].label
Ten weeks of aerobic training do not affect lower body negative pressure responses.

# publications[].label
Correction: Protein fractional synthesis rates within tissues of high- and low-active mice.

# publications[].label
Experimentally evolving exercise endurance: one step at a time.

# publications[].label
Environmental Endocrine Disruptor Affects Voluntary Physical Activity in Mice.

# publications[].label
The Gut Microbiome Modulates Diet's Effect on the Regulation of Physical Activity

# publications[].label
Strain screen and haplotype association mapping of wheel running in inbred mouse strains.

# publications[].label
An epistatic genetic basis for physical activity traits in mice.

# publications[].label
Interstrain variation in murine aerobic capacity.

# publications[].label
Effects of Supraphysiological Doses of Sex Steroids on Wheel Running Activity in Mice.

# publications[].label
The reproducibility of tolerance to lower-body negative pressure and its quantification.

# publications[].label
Differential protein expression in the nucleus accumbens of high and low active mice.

# publications[].label
Inter-individual variation in adaptations to endurance and resistance exercise training: genetic approaches towards understanding a complex phenotype.

# publications[].label
Repeatability and protocol comparability of presyncopal symptom limited lower body negative pressure exposures.

# publications[].label
Association between Mitochondrial DNA Sequence Variants and VO2 max Trainability.

# publications[].label
The McArdle's Mouse Model: Providing Important Insight into Skeletal Muscle Regulation.

# publications[].label
Genetic variation in the pleiotropic association between physical activity and body weight in mice.

# publications[].label
Alleles associated with physical activity levels are estimated to be older than anatomically modern humans.

# publications[].label
Endocrine-disruption And The Regulation Of Physical Activity And Mammary Gland Development In Mice

# publications[].label
Routledge Handbook of Sport and Exercise Systems Genetics

# publications[].label
Metabolic Differences in Essential Amino Acid Plasma Concentrations in High- and Low-Active Mice

# publications[].label
Sex hormone effects on physical activity levels: why doesn't Jane run as much as Dick?

# publications[].label
Adaptation to repeated presyncopal lower body negative pressure exposures.

# publications[].label
Genetics of regular exercise and sedentary behaviors.

# publications[].label
Sex hormones' regulation of rodent physical activity: a review.

# researcherOn[].label
Undoing the Damage: Reprogramming the Effects of Early High Sugar/ High Fat Diets Through Exercise

# researcherOn[].awardedBy.label
United States Army - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Texas A&M Center for Environmental Health Research

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# streetAddress
Texas A&M University; Health And Kinesiology; 4243 TAMU

# schools[]
School of Education and Human Development

# etdChairOf[].label
Cruthirds, Clayton (2015-05). The Effect of Various Housing Combinations on Voluntary Wheel Activity in Mice. Master's Thesis.

# etdChairOf[].label
Schmitt, Emily Elizabeth (2015-05). Endocrine Disruptors and the Regulation of Voluntary Physical Activity in Mice. Doctoral Dissertation.

# etdChairOf[].label
Ferguson, David Paul (2013-07). Skeletal Muscle as a Mechanism for Peripheral Regulation of Voluntary Physical Activity. Doctoral Dissertation.