# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# overview
My broad research interests are concerned with the sensory perception of the external chemical world. The central questions investigated in our laboratory are concerned with how animals detect and discriminate among the thousands of different chemical signals that "flood" the olfactory and taste organs. Our laboratory uses Drosophila as a model to study these problems because the Drosophilachemosensory systems are structurally and functionally very similar to those of mammals, yet they are smaller and somewhat less complex, which makes them excellent models to investigate the molecular and neural basis of olfaction and taste.

# keywords[]
1.1 Normal Biological Development And Functioning

# educationAndTraining[].organization.label
University of Zurich - (Zurich, Switzerland)

# educationAndTraining[].organization.label
Harvard University - (Cambridge, Massachusetts, United States)

# educationAndTraining[].organization.label
Columbia University - (New York, New York, United States)

# educationAndTraining[].organization.label
University of Zurich - (Zurich, Switzerland)

# awardsAndHonors[].label
Senior Fellow Award, Swiss National Science Foundation Laboratory of Dr. R. Axel

# awardsAndHonors[].label
College of Medicine, Research Excellence Award, Senior Division

# awardsAndHonors[].label
Long Term Fellow Award, European Molecular Biology Organization Laboratory of Dr. T. Maniatis

# publications[].label
Enhancing Perception of Contaminated Food through Acid-Mediated Modulation of Taste Neuron Responses (vol 24, pg 1969, 2014)

# publications[].label
Opposing chemosensory functions of closely related gustatory receptors.

# publications[].label
The gene virilizer is required for female-specific splicing controlled by Sxl, the master gene for sexual development in Drosophila.

# publications[].label
The molecular basis of sugar sensing in Drosophila larvae.

# publications[].label
Enhancing perception of contaminated food through acid-mediated modulation of taste neuron responses.

# publications[].label
A putative Drosophila pheromone receptor expressed in male-specific taste neurons is required for efficient courtship.

# publications[].label
Distinct molecular receptors mediate sweet and fatty acid taste through overlapping sets of taste neurons.

# publications[].label
Suppression of male courtship by a Drosophila pheromone receptor.

# publications[].label
Multiple RNA-protein interactions in Drosophila dosage compensation

# publications[].label
A spatial map of olfactory receptor expression in the Drosophila antenna.

# publications[].label
Genes expressed in neurons of adult male Drosophila.

# publications[].label
An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
A unified nomenclature system for the Drosophila odorant receptors. Drosophila Odorant Receptor Nomenclature Committee.

# publications[].label
Gluconeogenesis: An ancient biochemical pathway with a new twist.

# publications[].label
RNA Taste Is Conserved in Dipteran Insects.

# publications[].label
Drosophila Neuronal Glucose 6 Phosphatase is a modulator of Neuropeptide Release that regulates muscle glycogen stores via FMRFamide signaling.

# publications[].label
Function and expression of the Drosophila gr genes in the perception of sweet, bitter and pheromone compounds.

# publications[].label
Mechanism of Taste Perception in Drosophila

# publications[].label
Diverse roles for the Drosophila fructose sensor Gr43a.

# publications[].label
Vomeronasal organ: pheromone recognition with a twist.

# publications[].label
The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2.

# publications[].label
Genes expressed in the Drosophila head reveal a role for fat cells in sex-specific physiology.

# publications[].label
Taste and pheromone perception in mammals and flies.

# publications[].label
SIK3-HDAC4 signaling regulates Drosophila circadian male sex drive rhythm via modulating the DN1 clock neurons.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Genome-wide screen in adult drosophila to identify novel cardiomyopathy genes

# publications[].label
Pheromone perception and behavior in Drosophila.

# publications[].label
Drosophila as a model for the identification of genes causing adult human heart disease.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
A fructose receptor functions as a nutrient sensor in the Drosophila brain.

# publications[].label
Alternatively spliced transcripts of the sex-determining gene tra-2 of Drosophila encode functional proteins of different size.

# publications[].label
Multiple RNA-protein interactions in Drosophila dosage compensation.

# publications[].label
An expression system for Gustatory receptorsAnd why it failed

# publications[].label
Taste and pheromone perception in the fruit fly Drosophila melanogaster.

# publications[].label
Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction.

# publications[].label
Opposing chemosensory functions of closely related gustatory receptors.

# publications[].label
Chapter 14 Mechanism of Taste Perception in Drosophila

# publications[].label
Taste perception: how to make a gourmet mouse.

# publications[].label
A male-specific fatty acid omega-hydroxylase, SXE1, is necessary for efficient male mating in Drosophila melanogaster.

# publications[].label
Sensory biology: Thirsty glia motivate water consumption.

# publications[].label
Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system.

# publications[].label
Ionotropic Receptors Mediate Drosophila Oviposition Preference through Sour Gustatory Sensory Neurons

# publications[].label
Axons of Gustatory Receptor 32a Expressing Neurons Extend Their Terminal Throughout Adult Lifetime

# publications[].label
Neuronal Gluconeogenesis Regulates Systemic Glucose Homeostasis in Drosophila melanogaster.

# publications[].label
Gustatory perception and behavior in Drosophila melanogaster.

# publications[].label
A genetic tool kit for cellular and behavioral analyses of insect sugar receptors.

# publications[].label
Taste perception and coding in Drosophila.

# publications[].label
Ionotropic Receptors Mediate Drosophila Oviposition Preference through Sour Gustatory Receptor Neurons.

# publications[].label
The taste of ribonucleosides: Novel macronutrients essential for larval growth are sensed by Drosophila gustatory receptor proteins

# publications[].label
Ionotropic Receptors mediate sour and fatty acid taste in Drosophila

# publications[].label
Drosophila sugar receptors in sweet taste perception, olfaction, and internal nutrient sensing.

# publications[].label
Identification of a Drosophila glucose receptor using Ca2+ imaging of single chemosensory neurons.

# publications[].label
Hierarchical chemosensory regulation of male-male social interactions in Drosophila.

# publications[].label
Genetic control of sex determination in Drosophila.

# publications[].label
Genome-wide screen in adult drosophila to identify novel cardiomyopathy genes

# publications[].label
Molecular basis of fatty acid taste in Drosophila.

# publications[].label
Atypical expression of Drosophila gustatory receptor genes in sensory and central neurons.

# publications[].label
Opposing chemosensory functions of closely related gustatory receptors

# publications[].label
The taste of ribonucleosides: Novel macronutrients essential for larval growth are sensed by Drosophila gustatory receptor proteins.

# publications[].label
The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein.

# publications[].label
Bitter-sweet solution in taste transduction.

# publications[].label
Ventral lateral and DN1 clock neurons mediate distinct properties of male sex drive rhythm in Drosophila.

# publications[].publisher
Proceedings of the National Academy of Sciences

# researcherOn[].label
Regulation of Feeding Behavior by Brain-based Nutrient Sensors

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Deafness and Other Communication Disorders

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Modulation of peptidergic neurons by the gluconeogenic enzyme Glucose-6-Phosphatase

# researcherOn[].awardedBy.label
National Institute of Neurological Disorders and Stroke - (Bethesda, Maryland, United States)

# researcherOn[].label
Convergence of Cellular and Molecular Pathways in Appetitive Taste

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Deafness and Other Communication Disorders

# researcherOn[].label
Gustatory Receptors sense RNA and ribonuclcic acid metabolites as nutrients and signaling molecules during rapid growth

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Deafness and Other Communication Disorders

# researcherOn[].label
The taste of ribonucleosides: The molecular and cellular basis underlying chemosensory detection of previously unknown macronutrients

# researcherOn[].awardedBy.label
National Institute on Deafness and Other Communication Disorders - (Bethesda, Maryland, United States)

# streetAddress
Cell Biology and Genetics; School of Medicine; 4350 MREB 2

# schools[]
College of Agriculture and Life Sciences

# etdChairOf[].label
Yavuz, Ahmet E (2017-12). Molecular Basis of Sugar Sensing in Drosophila. Doctoral Dissertation.