# overview
My research focuses on studying the multi-scale biomechanics of healthy and diseased bone, the mechanical interaction between bone and orthopaedic implants, and the mechanobiological mechanism during bone remodeling.

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Stem Cell Research - Nonembryonic - Human

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Atomic Force Microscopy (afm) Nanomechanical Testing

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4007 Control Engineering, Mechatronics And Robotics

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Harbin Institute of Technology - (Harbin, China)

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Rutgers University - (New Brunswick, New Jersey, United States)

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Pennsylvania State University - (State College, Pennsylvania, United States)

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Johns Hopkins University School of Medicine - (Baltimore, Maryland, United States)

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Mechanical characterization of Col1a1+/ osteogenesis imperfecta bone revealed altered mechanical stiffness heterogeneity across scales

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Atomic force microscopy (AFM) and its applications to bone-related research.

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Full-field strain distribution in non-arthritic and arthritic glenoid bones before and after implant placement measured by digital volume correlation method

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3D Contact and Strain in Alveolar Bone Under Tooth/Implant Loading

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Voxel-based micro-finite element analysis of dental implants in a human cadaveric mandible: Tissue modulus assignment and sensitivity analyses.

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The microstructure of metastatic bone lesions suggests tumor mediated alterations in bone mineralization.

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An Ultrasensitive Calcium Reporter System via CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells.

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Elastic modulus mapping for bovine cortical bone from submillimeter-to submicron-scales using PeakForce Tapping atomic force microscopy

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Multi-scale investigation of orientation-dependent mechanical properties and fracture propagation in cortical bone using digital volume correlation and atomic force microscopy

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Effects of implant buccal distance on peri-implant strain: A Micro-CT based finite element analysis.

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3D full-field biomechanical testing of a glenoid before and after implant placement

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3D full-field strain in bone-implant and bone-tooth constructs and their morphological influential factors.

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Point-of-care treatment of geometrically complex midfacial critical-sized bone defects with 3D-Printed scaffolds and autologous stromal vascular fraction.

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Microstructure and mechanical behaviors of tibia for collagen-induced arthritic mice treated with gingiva-derived mesenchymal stem cells.

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Investigating simultaneous mineralization across layers during tooth development using atomic force microscopy and Raman spectroscopy.

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3D-printed oxygen-releasing scaffolds improve bone regeneration in mice.

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Spatiotemporal Mechanical Stimuli from Dental Crypt During Tooth Development: An Integrated Experimental and Computational Study

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Mechanical strength across metastatic lesions in trabecular bone: The interplay of microstructure and composition

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A biodegradable 3D woven magnesium-based scaffold for orthopedic implants.

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Three-dimensional printing of scaffolds for facial reconstruction

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Development of Biodegradable Osteopromotive Citrate-Based Bone Putty.

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Chapter 12 3D Printing for Craniofacial Bone Regeneration

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Human cell-derived dermal-specific interwoven extracellular matrix for diabetic wound healing.

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3D Full-Field Mechanical Measurement of a Shoulder Bone Under Implant Loading

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An investigation of the viscoelastic properties and the actin cytoskeletal structure of triple negative breast cancer cells.