# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# overview
My research is focused on fetal brain development, stem cells, microRNAs, and teratology.  Our laboratory is interested in understanding the biological steps that transform uncommitted stem cells into neurons or a glial cells, and identifying key microRNAs that control the transformation of stem cells into neurons.  We are also currently investigating what role teratogen-sensitive microRNAs play in fetal brain growth, and the spatial patterning of the emerging forebrain.

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Death Domain Receptor Signaling Adaptor Proteins

# keywords[]
Casp8 And Fadd-like Apoptosis Regulating Protein

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
9 Industry, Innovation And Infrastructure

# keywords[]
Stem Cell Research - Induced Pluripotent Stem Cell - Human

# keywords[]
Stem Cell Research - Induced Pluripotent Stem Cell

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Glial Cell Line-derived Neurotrophic Factor

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Preterm, Low Birth Weight And Health Of The Newborn

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Developmental Origin Of Health And Disease

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
2.3 Psychological, Social And Economic Factors

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
4009 Electronics, Sensors And Digital Hardware

# keywords[]
4201 Allied Health And Rehabilitation Science

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Src Homology 2 Domain-containing, Transforming Protein 1

# keywords[]
Glial Cell Line-derived Neurotrophic Factor

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Alzheimer's Disease Including Alzheimer's Disease Related Dementias (ad/adrd)

# keywords[]
Health Disparities And Racial Or Ethnic Minority Health Research

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Sicer, Spatial Clustering For Identification Of Chip-enriched Regions

# keywords[]
Vegf, Vascular Endothelial Growth Factor, Mrna

# keywords[]
Qpcr, Quantitative Polymerase Chain Reaction

# keywords[]
Iba-1, Ionized Calcium Binding Adaptor Molecule 1

# keywords[]
Pecam, Platelet Endothelial Cell Adhesion Molecule

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Stem Cell Research - Induced Pluripotent Stem Cell - Human

# keywords[]
Stem Cell Research - Induced Pluripotent Stem Cell

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Casp8 And Fadd-like Apoptosis Regulating Protein

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Developmental Origins Of Health And Disease

# keywords[]
Developmental Origin Of Health And Disease

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Glial Cell Line-derived Neurotrophic Factor

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
Health Disparities And Racial Or Ethnic Minority Health Research

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Conditions Affecting The Embryonic And Fetal Periods

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# educationAndTraining[].organization.label
Columbia University - (New York, New York, United States)

# educationAndTraining[].organization.label
University of Rochester - (Rochester, New York, United States)

# educationAndTraining[].organization.label
University of Rochester - (Rochester, New York, United States)

# educationAndTraining[].organization.label
University of Mumbai - (Mumbai, Maharashtra, India)

# educationAndTraining[].organization.label
University of Rochester - (Rochester, New York, United States)

# publications[].label
Prenatal Alcohol Exposure Worsens Stroke Outcomes In Young Rats And Exacerbates Brain Damage In Ischemic Middle- aged Rats

# publications[].label
Uncontrollable stimulation undermines recovery after spinal cord injury.

# publications[].label
Non-Coding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation: Implications for Stem Cell Therapy

# publications[].label
Prenatal alcohol and/or cannabinoid exposure in mice leads to motor impairments and changes in ethanol self-administration in adult offspring

# publications[].label
Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice.

# publications[].label
The extracellular matrix, p53 and estrogen compete to regulate cell-surface Fas/Apo-1 suicide receptor expression in proliferating embryonic cerebral cortical precursors, and reciprocally, Fas-ligand modifies estrogen control of cell-cycle proteins.

# publications[].label
Group I metabotropic glutamate receptors control metaplasticity of spinal cord learning through a protein kinase C-dependent mechanism.

# publications[].label
Maternal circulating miRNAs contribute to negative pregnancy outcomes by altering placental transcriptome and fetal vascular dynamics.

# publications[].label
P2236: microRNA mediated reversal of AD pathology

# publications[].label
Engaging pain fibers after a spinal cord injury fosters hemorrhage and expands the area of secondary injury.

# publications[].label
Electrically induced release of labelled taurine, alpha- and beta-alanine, glycine, glutamate and other amino acids from rat neocortical slices in vitro.

# publications[].label
PRENATAL ALCOHOL EXPOSURE AND NEURODEVELOPMENTAL STATUS AFFECT PLASMA MIRNAS EXPRESSION IN EARLY CHILDHOOD

# publications[].label
Proceedings of the 2010 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group.

# publications[].label
Ethanol induces Fas/Apo [apoptosis]-1 mRNA and cell suicide in the developing cerebral cortex.

# publications[].label
Optical coherence tomography angiography to evaluate murine fetal brain vasculature changes caused by prenatal exposure to nicotine.

# publications[].label
Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats.

# publications[].label
The BAF (BRG1/BRM-Associated Factor) chromatin-remodeling complex exhibits ethanol sensitivity in fetal neural progenitor cells and regulates transcription at the miR-9-2 encoding gene locus.

# publications[].label
Toxic and Teratogenic Effects of Prenatal Alcohol Exposure on Fetal Development, Adolescence, and Adulthood.

# publications[].label
Infant circulating MicroRNAs as biomarkers of effect in fetal alcohol spectrum disorders.

# publications[].label
Suppression and epigenetic regulation of MiR-9 contributes to ethanol teratology: evidence from zebrafish and murine fetal neural stem cell models.

# publications[].label
Prenatal alcohol exposure exacerbates acute sensorimotor deficits and impedes long-term behavioral recovery from the effects of an adult-onset cerebrovascular ischemic stroke.

# publications[].label
Maternal, paternal, and dual-parental alcohol exposures result in both overlapping and distinct impacts on behavior in adolescent offspring.

# publications[].label
Epigenetic Mechanisms and Inheritance of Acquired Susceptibility to Disease

# publications[].label
Theiler's murine encephalomyelitis virus induces rapid necrosis and delayed apoptosis in myelinated mouse cerebellar explant cultures.

# publications[].label
Micro RNA clusters in maternal plasma are associated with preterm birth and infant outcomes.

# publications[].label
Interactions of estrogen with the neurotrophins and their receptors during neural development.

# publications[].label
Abstract 172: Circulating Mirna Profiles Discriminate Stroke Severity Associated With Age and Sex

# publications[].label
Prenatal alcohol and/or cannabinoid exposure in mice changes motor coordination and ethanol self-administration in adult offspring

# publications[].label
Quantifying Changes in Fetal Brain Vasculature Due to Prenatal Cannabinoid Exposure Using Optical Coherence Tomography

# publications[].label
Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders.

# publications[].publisher
National Institute on Alcohol Abuse and Alcoholism

# publications[].label
MicroRNA dysregulation following spinal cord contusion: implications for neural plasticity and repair.

# publications[].label
Ethanol induces cell-cycle activity and reduces stem cell diversity to alter both regenerative capacity and differentiation potential of cerebral cortical neuroepithelial precursors.

# publications[].label
Electrically induced release of (3H)GABA from neocortical thin slices. Effects of stimulus waveform and of amino-oxyacetic acid.

# publications[].label
Use of video microscopy in teaching medical histology labs

# publications[].label
Hemorrhage and Locomotor Deficits Induced by Pain Input after Spinal Cord Injury Are Partially Mediated by Changes in Hemodynamics.

# publications[].label
Gonadal steroid receptors: Possible roles in the etiology and therapy of cognitive and neurological disorders

# publications[].label
Early Life Outcomes of Prenatal Exposure to Alcohol and Synthetic Cannabinoids in Mice.

# publications[].label
Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells.

# publications[].label
Histone methylation patterns in astrocytes are influenced by age following ischemia.

# publications[].label
Plasma miRNA Profiles in Pregnant Women Predict Infant Outcomes following Prenatal Alcohol Exposure.

# publications[].label
Chapter 7 Fetal alcohol spectrum disorders

# publications[].label
Insulin influences astroglial morphology and glial fibrillary acidic protein (GFAP) expression in organotypic cultures.

# publications[].label
Utilizing optical coherence angiography to assess the acute and multiple dose effects of prenatal alcohol exposure on fetal brain vasculature

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Abstract T P37: Routine CT Angiography in Acute Stroke Does Not Delay Acute Stroke Care

# publications[].label
Dose-response analysis of microvasculature changes in the murine fetal brain and the maternal extremities due to prenatal ethanol exposure.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
PRENATAL ALCOHOL AND CANNABINOID EXPOSURE DECREASES MOTOR COORDINATION AND INCREASES ETHANOL SELFADMINISTRATION IN ADULT MOUSE OFFSPRING.

# publications[].label
Chapter 30 Noncoding RNA regulatory networks, epigenetics, and programming stem cell renewal and differentiation implications for stem cell therapy

# publications[].label
When Pain Hurts: Nociceptive Stimulation Induces a State of Maladaptive Plasticity and Impairs Recovery after Spinal Cord Injury.

# publications[].label
EFFECTS OF BINGE PRENATAL ALCOHOL EXPOSURE ON CELL POPULATIONS IN THE FETAL MURINE CEREBRAL CORTEX USING SINGLE-CELL RNA SEQUENCING

# publications[].label
Reduced fetal cerebral blood flow predicts perinatal mortality in a mouse model of prenatal alcohol and cannabinoid exposure.

# publications[].label
Alcohol and Nicotine-Induced Epigenetic Changes (miRNAs)

# publications[].label
Transcriptome Analysis Of The Liver Reveals Novel Mechanisms By Which Prenatal Alcohol Exposure Contributes To Worse Stoke Outcome

# publications[].label
Microbiota and nutrition as risk and resiliency factors following prenatal alcohol exposure.

# publications[].label
Ethanol exposure during neurogenesis induces persistent effects on neural maturation: evidence from an ex vivo model of fetal cerebral cortical neuroepithelial progenitor maturation.

# publications[].label
Gag-like proteins: Novel mediators of prenatal alcohol exposure in neural development.

# publications[].label
Maternal circulating miRNAs that predict infant FASD outcomes influence placental maturation.

# publications[].label
Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure.

# publications[].label
Assessing the effects of prenatal poly-drug exposure on fetal brain vasculature using optical coherence angiography.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Assessing the acute effects of prenatal synthetic cannabinoid exposure on murine fetal brain vasculature using optical coherence tomography.

# publications[].label
Prenatal Exposure to Alcohol Induces Functional and Structural Plasticity in Dopamine D1 Receptor-Expressing Neurons of the Dorsomedial Striatum.

# publications[].label
Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression.

# publications[].label
Dose-related shifts in proteome and function of extracellular vesicles secreted by fetal neural stem cells following chronic alcohol exposure.

# publications[].label
FOC3FASDFOC3-1POSTNATAL CHOLINE SUPPLEMENTATION MODIFIES ALTERATIONS IN miRNAs INDUCED BY DEVELOPMENTAL ALCOHOL EXPOSURE

# publications[].label
Mechanisms of MicroRNA Function in Fetal Neural Stem Cells: Implications for Ethanol Teratology

# publications[].label
Abstract W MP82: False Negative Results on Acute Stroke Recognition Tool Has No Impact on Stroke Prognosis

# publications[].label
MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells.

# publications[].label
Hormone replacement: Therapeutic strategies in the treatment of Alzheimer's disease and ageing-related cognitive disorders

# publications[].label
The impact of PAE on adult disease: Cerebrovascular ischemic stroke as a case study

# publications[].label
Alcohol & cannabinoid co-use: Implications for impaired fetal brain development following gestational exposure.

# publications[].label
Association between fetal sex and maternal plasma microRNA responses to prenatal alcohol exposure: evidence from a birth outcome-stratified cohort.

# publications[].label
SEX AS A BIOLOGICAL VARIABLE FOR ETHANOL'S EFFECTS ON FETAL NEURAL STEM AND PROGENITOR CELLS

# publications[].label
Effects of sodium-deficient media and of a calcium ionophore (A-23187) on the release of (3H)-noradrenaline, (14C)-alpha-aminoisobutyrate, and (3H)-gamma-aminobutyrate from superfused slices of rat neocortex.

# publications[].label
Circulating miRNA profiles provide a biomarker for severity of stroke outcomes associated with age and sex in a rat model.

# publications[].label
Uncontrollable stimulation undermines recovery of function after spinal cord injury

# publications[].label
Peripheral noxious stimulation reduces withdrawal threshold to mechanical stimuli after spinal cord injury: role of tumor necrosis factor alpha and apoptosis.

# publications[].label
Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate.

# publications[].label
Ethanol Exposure Increases miR-140 in Extracellular Vesicles: Implications for Fetal Neural Stem Cell Proliferation and Maturation.

# publications[].label
Extracellular Vesicles in Premature Aging and Diseases in Adulthood Due to Developmental Exposures.

# publications[].label
Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation.

# publications[].label
Vascular Contributions to the Neurobiological Effects of Prenatal Alcohol Exposure.

# publications[].label
Cellular variations in estrogen receptor mRNA translation in the developing brain: evidence from combined [125I]estrogen autoradiography and non-isotopic in situ hybridization histochemistry.

# publications[].label
Effects of tetrodotoxin, elevated calcium and calcium antagonists on electrically induced 3H-noradrenaline release from brain slices.

# publications[].label
Nonprotein-coding RNAs in Fetal Alcohol Spectrum Disorders.

# publications[].label
Ethanol regulates angiogenic cytokines during neural development: evidence from an in vitro model of mitogen-withdrawal-induced cerebral cortical neuroepithelial differentiation.

# publications[].label
Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects.

# publications[].label
The interaction of genetic sex and prenatal alcohol exposure on health across the lifespan.

# publications[].label
Estrogen Differentially Regulates Estrogen and Nerve Growth Factor Receptor mRNAs in Adult Sensory Neurons

# publications[].label
SIMULTANEOUS PRENATAL ALCOHOL AND CANNABINOID EXPOSURE DURING THE SECOND TRIMESTER INHIBITS NEURAL STEM CELL GROWTH AND FETAL-DIRECTED BLOOD FLOW

# publications[].label
Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
The association between spinal cord trauma-sensitive miRNAs and pain sensitivity, and their regulation by morphine.

# publications[].label
Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies.

# publications[].label
Noncoding RNAs in development and teratology, with focus on effects of cannabis, cocaine, nicotine, and ethanol.

# publications[].label
Fetal Alcohol Spectrum Disorders: A StemCellopathy?

# publications[].label
Maternal Circulating MiRNAs That Predict Infant FASD Outcomes Influence Placental Maturation

# publications[].label
ALCOHOL'S EFFECT ON CRUCIAL BRAIN DEVELOPMENT PROTEIN DURING FETAL CORTICAL DEVELOPMENT

# publications[].label
Sex differences in the transcriptome of extracellular vesicles secreted by fetal neural stem cells and effects of chronic alcohol exposure.

# publications[].label
Sex specific effects of prenatal alcohol exposure across a lifespan

# publications[].label
Neuronal colocalization of mRNAs for neurotrophins and their receptors in the developing central nervous system suggests a potential for autocrine interactions.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Critically timed ethanol exposure reduces GABAAR function on septal neurons developing in vivo but not in vitro.

# publications[].label
Assessing the effects of prenatal cannabinoid consumption on fetal brain vasculature utilizing optical coherence angiography

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period.

# publications[].label
Embryonic cerebral cortical progenitors are resistant to apoptosis, but increase expression of suicide receptor DISC-complex genes and suppress autophagy following ethanol exposure.

# publications[].label
MicroRNAs and Fetal Brain Development: Implications for Ethanol Teratology during the Second Trimester Period of Neurogenesis.

# publications[].label
Early developmental exposure to benzodiazepine ligands alters brain 31P-NMR spectra in young adult rats.

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Chapter 25 Non-Coding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation Implications for Stem Cell Therapy

# publications[].label
Regulatory effects of intermittent noxious stimulation on spinal cord injury-sensitive microRNAs and their presumptive targets following spinal cord contusion.

# publications[].label
NOVEL MEDIATORS OF PRENATAL ALCOHOL EFFECTS IN NEURAL STEM CELLS: GAG-LIKE PROTEINS IN INTERCELLULAR COMMUNICATION

# publications[].label
Expression of brain-derived neurotrophic factor and its cognate receptor, TrkB, in the rat suprachiasmatic nucleus.

# publications[].label
ALTERATIONS INTHE PROTEOMEOF EXTRACELLULAR VESICLES SECRETED BY NEURAL STEM CELLS AS A MEANS FOR INTERCELLULAR TRANSFER OF STRESS SIGNALS FOLLOWING DEVELOPMENTAL ETHANOL EXPOSURE

# publications[].label
Long-term effects of prenatal alcohol and/or cannabinoid exposure on gut microbiota and metabolites in adult mice offspring

# publications[].label
Optical imaging of the effects of maternal alcohol exposure on fetal brain microvasculature

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Optical coherence angiography to assess the combined effects of alcohol and nicotine on fetal brain vasculature

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
MATERNAL CIRCULATING MIRNAS AND ALCOHOL IMPACT FETAL VASCULAR DYNAMICS AND PLACENTAL TRANSCRIPTOME

# publications[].label
Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium.

# publications[].label
Aging-related changes in brain metabolism are altered by early developmental exposure to diazepam.

# publications[].label
Mechanisms of microRNA function in fetal neural stem cells: implications for ethanol teratology

# publications[].label
Reduction of APOE accounts for neurobehavioral deficits in fetal alcohol spectrum disorders.

# publications[].label
Toxicant and teratogenic effects of prenatal alcohol.

# publications[].label
Prenatal alcohol exposure worsens acute but not long-term cognitive outcomes due to stroke in middle-aged Sprague-Dawley rat offspring.

# publications[].label
TRANSCRIPTOME ANALYSIS OF MESENTERIC ADIPOSE TISSUE AND LIVER REVEALS NOVEL MECHANISTIC LINKAGES BETWEEN PRENATAL ALCOHOL EXPOSURE AND ADULT HEALTH OUTCOMES

# publications[].label
Evaluating changes in brain vasculature of murine embryos in utero due to maternal alcohol consumption using optical coherence tomography

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Comparative assessments of the effects of alcohol exposure on fetal brain development using optical coherence tomography and ultrasound imaging.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Abstract 131: Effect of Fetal Alcohol Exposure on Stroke Severity and Blood Flow in Adult Mice

# publications[].label
Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum.

# publications[].label
Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain

# publications[].label
Senescence-associated genes are differentially expressed by biological sex and following prenatal alcohol exposure in fetal neural stem cells

# publications[].label
Ethanol exposure during pregnancy persistently attenuates cranially directed blood flow in the developing fetus: evidence from ultrasound imaging in a murine second trimester equivalent model.

# publications[].label
Chapter 24 MicroRNAs in Alcohol Abuse and Toxicity

# publications[].label
Maternal and neonatal plasma microRNA biomarkers for fetal alcohol exposure in an ovine model.

# publications[].label
Prenatal alcohol alters inflammatory signatures in enteric portal tissues following adult-onset cerebrovascular ischemic stroke.

# publications[].label
Neurotrophin and neurotrophin receptors in vascular smooth muscle cells. Regulation of expression in response to injury.

# publications[].label
Combining Nonisotopic In Situ Hybridization Histochemistry with Steroid Autoradiography

# publications[].label
Cell-type and fetal-sex-specific targets of prenatal alcohol exposure in developing mouse cerebral cortex.

# publications[].label
PRENATAL ALCOHOL AND/OR CANNABINOID EXPOSURE IN MICE LEADS TO SEX-SPECIFIC MOTOR IMPAIRMENTS AND ETHANOL SELF-ADMINISTRATION IN ADULT OFFSPRING

# publications[].label
Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Opposing actions of ethanol and nicotine on microRNAs are mediated by nicotinic acetylcholine receptors in fetal cerebral cortical-derived neural progenitor cells.

# publications[].label
Prenatal opioid-exposed infant extracellular miRNA signature obtained at birth predicts severity of neonatal opioid withdrawal syndrome.

# publications[].label
CD24 expression identifies teratogen-sensitive fetal neural stem cell subpopulations: evidence from developmental ethanol exposure and orthotopic cell transfer models.

# publications[].label
Nerve growth factor (NGF) regulation of estrogen receptors in explant cultures of the developing forebrain.

# publications[].label
A comparison of microvasculature changes in the fetal brain and maternal extremities due to prenatal alcohol exposure using optical coherence angiography

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Prenatal alcohol exposure worsens acute and long-term stroke outcomes in adult Sprague-Dawley rats with sex-specific effects

# publications[].label
Assessing the effects of prenatal cannabinoid consumption on fetal brain vasculature utilizing optical coherence tomography angiography

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Developmental consequences of abnormal folate transport during murine heart morphogenesis.

# publications[].label
HIPPOCAMPAL AND CEREBELLAR TRANSCRIPTOME ANALYSIS REVEAL KEY PATHWAYS ALTERED BY PRENATAL ALCOHOL EXPOSURE

# publications[].label
Early developmental exposure to benzodiazepine ligands alters brain levels of thiobarbituric acid-reactive products in young adult rats.

# publications[].label
Overlapping and divergent actions of estrogen and the neurotrophins on cell fate and p53-dependent signal transduction in conditionally immortalized cerebral cortical neuroblasts.

# publications[].label
Effect of Alcohol Exposure on Fetal Brain Development

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Commentary: will analyzing the epigenome yield cohesive principles of ethanol teratology?

# publications[].label
Challenges of diagnosing fetal alcohol spectrum disorders in foster and adopted children.

# publications[].label
Noncoding RNA and Alcohol Use Disorder: A Scoping Review of Current Research and Knowledge Gaps.

# publications[].publisher
National Institute on Alcohol Abuse and Alcoholism

# publications[].label
Metaplasticity and behavior: how training and inflammation affect plastic potential within the spinal cord and recovery after injury.

# publications[].label
Instrumental learning within the rat spinal cord: localization of the essential neural circuit.

# publications[].label
NONCODING RNA REGULATORY NETWORKS, EPIGENETICS, AND PROGRAMMING STEM CELL RENEWAL AND DIFFERENTIATION: IMPLICATIONS FOR STEM CELL THERAPY

# publications[].label
Assessing miRNAs as predictive features in classifying PAE-associated neurodevelopmental delay

# publications[].label
Alcohol Regulates Genes that Are Associated with Response to Endocrine Therapy and Attenuates the Actions of Tamoxifen in Breast Cancer Cells.

# publications[].label
Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB.

# publications[].label
Early life outcomes of prenatal exposure to alcohol and synthetic cannabinoids in mice.

# publications[].label
Application of correlation mapping optical coherence angiography to study the impact of prenatal cannabinoid exposure on fetal brain vasculature

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.

# publications[].label
Instrumental learning within the spinal cord: underlying mechanisms and implications for recovery after injury.

# publications[].label
CELL-TYPE AND SEX-SPECIFIC TARGETS OF PRENATAL ALCOHOL EXPOSURE IN THE DEVELOPING MOUSE CEREBRAL CORTEX: IDENTIFICATION OF NOVEL MECHANISMS FOR TERATOGENESIS

# publications[].label
CIRCULATING MICRORNA BIOMARKERS FOR INFANT NEURODEVELOPMENTAL DEFICITS DUE TO PRENATAL ALCOHOL EXPOSURE

# publications[].label
Using in utero optical coherence tomography to evaluate changes in murine fetal brain vasculature due to prenatal exposure to teratogens (Conference Presentation)

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Evaluating the effects of maternal alcohol consumption on murine fetal brain vasculature using optical coherence tomography.

# publications[].label
Prevalence of Prenatal Alcohol Exposure in the State of Texas as Assessed by Phosphatidylethanol in Newborn Dried Blood Spot Specimens.

# publications[].label
Optical coherence angiography to assess the dose-effect relationship of prenatal alcohol exposure on fetal brain vasculature

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
An antagomir to microRNA Let7f promotes neuroprotection in an ischemic stroke model.

# publications[].label
Epigenetic mediators and consequences of excessive alcohol consumption.

# publications[].label
Utilizing optical coherence angiography to assess the acute and persistent effects of prenatal alcohol exposure on fetal brain vasculature in utero

# publications[].label
MicroRNAs: master regulators of ethanol abuse and toxicity?

# publications[].label
Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons.

# publications[].label
A report on the Fetal Alcohol Spectrum Disorders Study Group meeting of 2012, theme title, "Biomarkers for FASD".

# publications[].tags
16 Peace, Justice and Strong Institutions

# publications[].label
Presumptive Estrogen Target Neurons Express mRNAs for both the Neurotrophins and Neurotrophin Receptors: A Basis for Potential Developmental Interactions of Estrogen with the Neurotrophins.

# publications[].label
Identifying the mediating role of prenatal alcohol exposure on X-chromosome inactivating long-non-coding RNAs in a sex-dependent manner

# publications[].label
A teratogen-sensitive microRNA, miR335 controls the maturation of foetal neuroepithelial progenitors

# publications[].label
Abstract WP153: Prenatal Alcohol Exposure Induces Glucose Intolerance and Exacerbates Stroke Severity in Middle-Aged Rats

# publications[].label
In utero optical coherence tomography reveals changes in murine embryonic brain vasculature after prenatal cannabinoid exposure

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Quantifying changes in murine fetal brain vasculature due to prenatal exposure to teratogens with in utero optical coherence tomography

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
HEALTH OUTCOMES OF ADULTS WITH FETAL ALCOHOL SPECTRUM DISORDERS: A FETAL BASIS TO ADULT DISEASE

# publications[].label
Reduced fetal cerebral blood flow following prenatal drug exposure predicts perinatal mortality

# publications[].label
Glial-derived neurotrophic factor (GDNF) prevents ethanol-induced apoptosis and JUN kinase phosphorylation.

# publications[].label
Developmental expression of estrogen receptor mRNA in the rat cerebral cortex: a nonisotopic in situ hybridization histochemistry study.

# publications[].label
Neonatal Cord Blood miRNAs As Biomarkers of Neonatal Opioid Withdrawal Syndrome

# publications[].label
Perinatal and prenatal alcohol exposure impairs striatal cholinergic function and cognitive flexibility in adult offspring.

# publications[].label
ETHANOL EXPOSURE DISRUPTS FMR1 AND NFIA PARENT GENE/LNCRNA BALANCE LEADING TO ABERRANT CORTICAL NEURAL STEM CELL DIFFERENTIATION

# publications[].label
A novel Oct4/Pou5f1-like non-coding RNA controls neural maturation and mediates developmental effects of ethanol.

# publications[].label
Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure.

# publications[].label
Prenatal alcohol exposure contributes to negative pregnancy outcomes by altering fetal vascular dynamics and the placental transcriptome.

# publications[].label
Prenatal Alcohol Exposure Impairs Long-term Behavioral Recovery Following Ischemic Stroke In Sprague Dawley Rats

# publications[].label
Binge consumption of ethanol during pregnancy leads to significant developmental delay of mouse embryonic brain

# publications[].publisher
SPIE, the international society for optics and photonics

# researcherOn[].label
Epigenetics of the Aging Astrocyte: Implications for Stroke

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Nociceptive Input After Spinal Cord Injury (SCI) Expands the Region of Secondary Injury and Undermines Long-Term Recovery

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Neurological Disorders and Stroke

# researcherOn[].label
Gag-like Proteins in Exosome-mediated Neural Development and Fetal Alcohol Spectrum Disorders

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Alcohol Abuse and Alcoholism (NIAAA)

# researcherOn[].label
Prenatal alcohol/cannabinoid co-exposures and fetal brain development

# researcherOn[].awardedBy.label
National Institute On Alcohol Abuse and Alcoholism - (Bethesda, Maryland, United States)

# researcherOn[].label
Prenatal microRNA Neuro-Therapeutics for Fetal Alcohol Exposure

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Alcohol Abuse and Alcoholism (NIAAA)

# researcherOn[].label
From FASD to AUDs: Strategies for Preventing Alcohol Addictions

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Neurological Disorders and Stroke

# researcherOn[].label
Neuroprotection In the Aging Female Brain

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Neurological Disorders and Stroke

# researcherOn[].label
Prenatal Alcohol and Stroke Susceptibility in the Aging Adult with FASD

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Alcohol Abuse and Alcoholism (NIAAA)

# researcherOn[].label
How and when does peripheral input affect recovery after SCI

# researcherOn[].awardedBy.label
Craig H Neilsen Foundation - (Los Angeles, California, United States)

# researcherOn[].label
Maternal Circulating miRNA Function In Fetal Alcohol Spectrum Disorders

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Alcohol Abuse and Alcoholism (NIAAA)

# streetAddress
Texas A&M Health Science Center; Neuroscience & Experimental Therapeutics; 1359 TAMUS

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine

# schools[]
Texas A&M University Naresh K. Vashisht College of Medicine

# etdChairOf[].label
Holgate, Rhonda Renay (2015-05). Ethanol Targeting nELAVs: Implications for Neural Stem Cell Maturation. Doctoral Dissertation.

# etdChairOf[].label
Tsai, Pai Chi (2014-05). miR-153 and miR-335, Ethanol Sensitive MicroRNAs, Control NSC/NPC Maturation during Fetal Brain Development. Doctoral Dissertation.

# etdChairOf[].label
Al Muhisen, Hadil Mahdi J (2018-08). Sex Differences in Fetal Neural Stem Cells’ Response to Ethanol. Master's Thesis.

# etdChairOf[].label
Raymond, Elizabeth S (2016-08). Effects of the Developmental Teratogens Ethanol and Nicotine on Long Noncoding RNA Expression in Mouse Fetal Neural Stem Cells of the Cortex. Master's Thesis.

# etdChairOf[].label
Strickland, Eric (2013-08). MicroRNA Dysregulation Following Spinal Cord Contusion: Implications for Neural Plasticity and Neuropathic Pain. Doctoral Dissertation.