# overview
The research in this laboratory is focused around questions concerning chromosomal rearrangement and it role(s) in vertebrate evolution. Although this usually involves assessments of intraspecific (populational) chromosomal polymorphism, the data are generally applicable to systematic interpretations and considerable attention is paid to the phylogenetic relationships and higher taxonomic patterns of chromosomal evolution. The systematic relationships of the species studied are typically used to establish the experimental design of the hypotheses tested. Our assessments of karyotypic rearrangement and chromosomal homology involve analyses of non-differentially stained and specifically- banded metaphase chromosomes. Although deer mice (Peromyscus) are our primary model, recent projects have also addressed cytogenetic questions in birds and reptiles. The laboratory contains complete facilities for light microscopy and imaging, tissue culturing and allozymic analyses.

# educationAndTraining[].organization.label
Hofstra University - (Hempstead, New York, United States)

# educationAndTraining[].organization.label
Texas Tech University - (Junction, Texas, United States)

# educationAndTraining[].organization.label
Texas Tech University - (Junction, Texas, United States)

# publications[].label
Fragility in the 14q21q translocation region

# publications[].label
Microsatellite variation and evolution in the Peromyscus maniculatus species group.

# publications[].label
GENIC VARIATION AMONG WESTERN CYTOTYPES OF PEROMYSCUS-MANICULATUS

# publications[].label
Meiosis in chromosomally heteromorphic goitered gazelle, Gazella subgutturosa (Artiodactyla, Bovidae).

# publications[].label
THE ROLE OF CHROMOSOMAL REARRANGEMENT IN SPECIATION - MEIOTIC EVIDENCE FROM POPULATIONAL POLYMORPHISMS

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APPLICATION OF SYNAPTONEMAL COMPLEX TECHNIQUES FOR DETERMINATION OF DIPLOID NUMBER AND CHROMOSOMAL MORPHOLOGY IN BIRDS

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KARYOTYPIC VARIATION IN PEROMYSCUS-BOYLII FROM MEXICO

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SIMULATION STUDIES ON THE ACCURACY OF THE SPARSE-DATA APPROXIMATIONS AND THE MINIMUM RELIABLE SAMPLE SIZES FOR FSM IDENTIFICATIONS OF FRAGILE SITES - PRELIMINARY-RESULTS

# publications[].label
The behavior and morphology of the X and Y chromosomes during prophase I in the Sitka deer mouse (Peromyscus sitkensis).

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CYTOGENETIC ANALYSIS OF B-CHROMOSOMAL PAIRING IN COLLARED LEMMINGS

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Comparative anatomy and general histology of tongues of long-nosed bats (Leptonycteris sanborni and L. nivalis) with reference to infestation of oral mites.

# publications[].label
Probability models and the applicability of statistical procedures in the identification of chromosomal fragile sites.

# publications[].label
BIOCHEMICAL AND KARYOTYPIC VARIATION IN PEROMYSCUS-MANICULATUS FROM WESTERN NORTH-AMERICA

# publications[].label
Centriolar length variability in testicular cells from side-necked turtles.

# publications[].label
How common are common fragile sites: variation of aphidicolin-induced chromosomal fragile sites in a population of the deer mouse (Peromyscus maniculatus).

# publications[].label
CHROMOSOMAL HOMOLOGY AND DIVERGENCE BETWEEN SIBLING SPECIES OF DEER MICE: PEROMYSCUS MANICULATUS AND P. MELANOTIS (RODENTIA, CRICETIDAE).

# publications[].label
Erratum: Selective oncolytic effect of an attenuated Newcastle disease virus (NDV-HUJ) in lung tumors

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EVOLUTIONARY IMPLICATIONS OF GENIC VARIATION AMONG INSULAR POPULATIONS OF PEROMYSCUS-MANICULATUS AND PEROMYSCUS-OREAS

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BIOCHEMICAL CHARACTERS AND THE RECONSTRUCTION OF TURTLE PHYLOGENIES - RELATIONSHIPS AMONG BATAGURINE GENERA

# publications[].label
Heterosynapsis and axial equalization of the sex chromosomes of the northern bobwhite quail.

# publications[].label
Chromosomal pairing in deer mice heterozygous for the presence of heterochromatic short arms.

# publications[].label
Variation of aphidicolin-induced chromosomal fragile sites in a population of deer mice

# publications[].label
The mechanism of autosomal synapsis and the substaging of zygonema and pachynema from deer mouse spermatocytes.

# publications[].label
Synapsis, recombination, and meiotic segregation in the mesquite lizard, Sceloporus grammicus, complex. II. Fission heteromorphism of the FM2 cytotype and evolution of chromosome 2.

# publications[].label
BIOCHEMICAL SYSTEMATICS AND EVOLUTION IN THE SOUTH-AMERICAN TURTLE GENUS PLATEMYS (PLEURODIRA, CHELIDAE)

# publications[].label
Allozymic Variation and Biogeography of Snapping Shrimp (Alpheus) from the Gulf of Mexico and Northwestern Atlantic Coasts

# publications[].label
CYTOGENETIC ANALYSIS OF CHROMOSOMAL INTERMEDIATES FROM A HYBRID ZONE BETWEEN TWO CHROMOSOME RACES OF THE SCELOPORUS GRAMMICUS COMPLEX (SAURIA, PHRYNOSOMATIDAE).

# publications[].label
Populational variation of chromosomal fragility in the deer mouse (Peromyscus maniculatus)

# publications[].label
Spontaneous occurrence of XYY primary spermatocytes in the Sitka deer mouse.

# publications[].label
EVOLUTIONARY IMPLICATIONS OF CHROMOSOMAL POLYMORPHISMS IN PEROMYSCUS BOYLII FROM SOUTHWESTERN MEXICO.

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CYTOGENETIC ANALYSIS OF THE NEO-XY SEX-CHROMOSOMAL SYSTEM OF COLLARED LEMMINGS

# publications[].label
CHROMOSOMAL FRAGILE SITES IN THE DEER MOUSE - DISTRIBUTION, VARIATION, AND POTENTIAL ROLE IN CHROMOSOMAL EVOLUTION

# publications[].label
BIOCHEMICAL VARIATION IN PYGMY MICE (BAIOMYS)

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CHROMOSOMAL HOMOLOGY AND EVOLUTIONARY RELATIONSHIPS OF PEROMYSCUS-SEJUGIS AND P-SLEVINI

# publications[].label
Mitochondrial-DNA analysis of the systematic relationships within the Peromyscus maniculatus species group

# publications[].label
Microsatellite markers for the deer mouse Peromyscus maniculatus.

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Cytogenetics of collared lemmings (Dicrostonyx groenlandicus). I. Meiotic behavior and evolution of the neo-XY sex-chromosome system.

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BIOCHEMICAL SYSTEMATICS OF NEOTROPICAL TURTLES OF THE GENUS RHINOCLEMMYS (EMYDIDAE, BATAGURINAE)

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KARYOTYPIC CONSERVATISM IN THE PEROMYSCUS-MEXICANUS GROUP

# publications[].label
Genealogical concordance and the specific status of Peromyscus sejugis.

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Synaptonemal complex analysis of mole rats (Spalax ehrenbergi): unusual polymorphisms of chromosome 1.

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Visualization of kinetochores in mammalian meiotic preparations and observations of argentophilic differences between mitotic and meiotic kinetochores.

# publications[].label
Selective oncolytic effect of an attenuated Newcastle disease virus (NDV-HUJ) in lung tumors.

# publications[].label
Meiotic analysis of chromosomal rearrangements and their potential role in reproductive isolation in collared lemmings

# publications[].label
SYSTEMATIC AND TAXONOMIC IMPLICATIONS OF KARYOTYPIC, ELECTROPHORETIC, AND MITOCHONDRIAL-DNA VARIATION IN PEROMYSCUS FROM THE PACIFIC-NORTHWEST

# publications[].label
Preliminary analysis for the conservation and evolution of aphidicolin-induced fragile sites among three species of Peromyscus

# publications[].label
Biochemical Characters and the Reconstruction of Turtle Phylogenies: Relationships among Batagurine Genera

# publications[].label
Allozymic Differences between Black and White Crappies

# publications[].label
Synapsis of a chromosomal pair heterozygous for a pericentric inversion and the presence of a heterochromatic short arm.

# publications[].label
The effect of heterochromatin on synapsis of the sex chromosomes of Peromyscus (Rodentia, Cricetidae).

# publications[].label
Identifying chromosomal fragile sites from individuals: a multinomial statistical model.

# publications[].label
APHIDICOLIN INDUCED FRAGILE SITES IN DEER MICE (PEROMYSCUS-MANICULATUS)

# publications[].label
GEOGRAPHIC-VARIATION IN GENITAL MORPHOLOGY AMONG INSULAR AND MAINLAND POPULATIONS OF PEROMYSCUS-MANICULATUS AND PEROMYSCUS-OREAS

# publications[].label
Unequal crossing over and heterochromatin exchange in the X-Y bivalents of the deer mouse, Peromyscus beatae.

# publications[].label
Mitochondrial DNA sequence variation and the specific identification of deer mice (Peromyscus) from Triangle Island, British Columbia, Canada

# publications[].label
SYNAPTIC ADAPTATION IN DEER MICE: A CELLULAR MECHANISM FOR KARYOTYPIC ORTHOSELECTION.

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SYNAPTONEMAL COMPLEX-ANALYSIS OF MOLE RATS (SPALAX-EHRENBERGI) - UNUSUAL POLYMORPHISMS OF CHROMOSOME-1

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KARYOTYPIC ANALYSES OF DEER MICE FROM WASHINGTON-STATE

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Mus and Peromyscus chromosome homology established by FISH with three mouse paint probes.

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Cytogenetic analysis of the pleurodine turtle Phrynops hogei and its taxonomic implications

# publications[].label
Evidence for heterosynaptic pairing of the inverted segment in pericentric inversion heterozygotes of the deer mouse (Peromyscus maniculatus).

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Reconsideration of the binomial and F distribution relationship as a test for nonrandomness of chromosomal breakage.

# publications[].label
Evolutionary Relationships in Macrotus (Mammalia: Chiroptera): Biochemical Variation and Karyology

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MORPHOLOGICAL PROPERTIES OF GAP-JUNCTIONS IN A VIRUS-TRANSFORMED GRANULOSA-CELL LINE

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GENETIC INTERACTIONS BETWEEN HYBRIDIZING CYTOTYPES OF THE TENT-MAKING BAT (URODERMA BILOBATUM).

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GENETIC-RELATIONSHIPS AMONG 8 SPECIES OF EPTESICUS AND PIPISTRELLUS (CHIROPTERA, VESPERTILIONIDAE)

# publications[].label
DYNAMICS OF A NOVEL CHROMOSOMAL POLYMORPHISM WITHIN A HYBRID ZONE BETWEEN TWO CHROMOSOME RACES OF THE SCELOPORUS GRAMMICUS COMPLEX (SAURIA, PHRYNOSOMATIDAE).

# publications[].label
Chromosomal synapsis and the meiotic process in male mesquite lizards, Sceloporus grammicus complex.

# publications[].label
Systematic implications of chromosomal data from two insular species of Peromyscus from the Gulf of California.

# publications[].label
Molecular phylogenetics of western deer mice (Peromyscus): Taxonomic and biogeographic implications

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CHROMOSOME EVOLUTION IN THE IGUANID LIZARD SCELOPORUS GRAMMICUS. II. ALLOZYME VARIATION.

# publications[].label
AN ANALYSIS OF ALLOZYME VARIATION, GENETIC SUBDIVISION, AND GENE FLOW BETWEEN POPULATIONS OF 3 ALLOPATRIC SUBSPECIES OF THE PHYLLOSTOMID BAT STURNIRA-LILIUM

# publications[].label
Minimum sample sizes for identifying chromosomal fragile sites from individuals: Monte Carlo estimation.

# publications[].label
Standardized karyotype of deer mice, Peromyscus (Rodentia). The Committee for Standardization of Chromosomes of Peromyscus.

# publications[].label
Synapsis, recombination, and meiotic segregation in the mesquite lizard, Sceloporus grammicus, complex. I. Pericentric inversion heteromorphism of the F5 cytotype.

# publications[].label
MORPHOLOGICAL VARIATION AND TAXONOMY OF CHROMOSOMALLY DIFFERENTIATED PEROMYSCUS FROM THE PACIFIC NORTHWEST

# publications[].label
ADDITIONAL NOTES ON KARYOTYPIC VARIATION IN THE PEROMYSCUS-BOYLII SPECIES GROUP

# publications[].label
Biochemical variation and genic similarity of myotis velifer and macrotus californicus.

# publications[].label
COMPARATIVE-ANALYSIS OF FRAGILE SITES IN 2 SPECIES OF PEROMYSCUS

# publications[].label
Cytogenetics of collared lemmings (Dicrostonyx groenlandicus). II. Meiotic behavior of B chromosomes suggests a Y-chromosome origin of supernumerary chromosomes.

# publications[].label
CYTOSYSTEMATIC VALUE OF CHROMOSOMAL INVERSION DATA IN THE GENUS PEROMYSCUS (RODENTIA, CRICETIDAE)

# publications[].label
OCCURRENCE OF INDUCED CHROMOSOMAL BREAKS IN EUCHROMATIN VS HETEROCHROMATIN

# publications[].label
How common are common fragile sites in humans: interindividual variation in the distribution of aphidicolin-induced fragile sites.

# publications[].label
Synaptic adjustment in Peromyscus beatae (Rodentia: Cricetidae) heterozygous for interstitial heterochromatin.

# publications[].label
Cytogenetic nomenclature of deer mice, Peromyscus (Rodentia): revision and review of the standardized karyotype. Report of the Committee for the Standardization of Chromosomes of Peromyscus.

# publications[].label
Karyotypic variation in populations of deer mice (Peromyscus maniculatus) from eastern Canada and the northeastern United States

# publications[].label
SYSTEMATIC IMPLICATIONS OF KARYOTYPIC AND MORPHOLOGICAL VARIATION IN MAINLAND PEROMYSCUS FROM THE PACIFIC-NORTHWEST

# publications[].label
Determination of the primitive karyotype for Peromyscus.

# publications[].label
Chromosomal fragility and the 14q21q translocation.

# publications[].label
BIOCHEMICAL VARIATION IN ALPHEUS (DECAPODA, CARIDEA, ALPHEIDAE) FROM THE COAST OF TEXAS - EVIDENCE FOR CRYPTIC SPECIES

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A PROBLEMATIC SPECIMEN OF PEROMYSCUS WITH AN UNUSUAL KARYOTYPE

# publications[].label
Variation in mitochondrial DNA in populations of Peromyscus eremicus from the Chihuahuan and Sonoran deserts

# publications[].label
MOLECULAR PHYLOGENETICS OF WESTERN DEER MICE (PEROMYSCUS): TAXONOMIC AND BIOGEOGRAPHIC IMPLICATIONS

# publications[].label
SYNAPTONEMAL COMPLEX-ANALYSIS OF SEX-CHROMOSOME PAIRING IN THE COMMON GROUND SKINK, SCINCELLA-LATERALIS (SAURIA, SCINCIDAE)

# streetAddress
Texas A&M University; Biology; 3258 TAMU

# etdChairOf[].label
Walker, Mindy Lynn (2005-12). Mitochondrial-DNA variation and the evolutionary affinities of the Peromyscus maniculatus complex from western North America. Doctoral Dissertation.

# etdChairOf[].label
Chirhart, Scott Edward (2003-08). Evolutionary implications of microsatellite variation in the Peromyscus maniculatus species group. Doctoral Dissertation.