# positions[].label
Associate Dean for Faculty Affairs and Curriculum Management

# positions[].organizations[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# overview
My research focuses on the effects of substance abuse (alcohol, cocaine, nicotine, etc.) on the developing brain; Polydrug interactions on brain and cognitive developments; Fetal alcohol syndrome; Use of 3-dimensional stereological cell counting techniques, immunohistochemistry, radioimmunoassay, high-performance liquid chromatograph, gas chromatograph and behavioral assessments in animal models such as rodent, ovine and zebrafish.

# keywords[]
AODR (alcohol And Other Drug Related) Behavioral Problem

# keywords[]
Dulbecco's Modified Eagle's Medium (DMEM) With Phosphates

# educationAndTraining[].organization.label
State University of New York - (Albany, New York, United States)

# educationAndTraining[].organization.label
University of Iowa - (Iowa City, Iowa, United States)

# awardsAndHonors[].label
Association of Former Students University-Level Distinguished Achievement Award, The

# awardsAndHonors[].label
Presidential Professor for Teaching Excellence Award

# publications[].label
4-Methylpyrazole, an alcohol dehydrogenase inhibitor, exacerbates alcohol-induced microencephaly during the brain growth spurt.

# publications[].label
Alcohol and the developing brain: Neuroanatomical studies

# publications[].label
Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage.

# publications[].label
Prenatal binge-like alcohol exposure alters neurochemical profiles in fetal rat brain.

# publications[].label
Disruptive influence of norepinephrine depletion on sensory preconditioning, but not first-order conditioning, in preweanling rats.

# publications[].label
Effects of developmental alcohol exposure on vasoactive intestinal polypeptide and voltage-dependent calcium channel expression in rat SCN and cerebellum.

# publications[].label
Effects of all three trimester moderate binge alcohol exposure on the foetal hippocampal formation and olfactory bulb.

# publications[].label
First trimester binge alcohol exposure results in a significant loss of fetal cerebellar purkinje cells: Sheep model

# publications[].label
Gender-related response in open-field activity following developmental nicotine exposure in rats.

# publications[].label
Olfactory bulb mitral cell numbers are not decreased by all three trimester alcohol exposure in fetal sheep

# publications[].label
Neonatal alcohol and nicotine exposure limits brain growth and depletes cerebellar Purkinje cells.

# publications[].label
Use of liquid diet administration in prenatal alcohol studies may increase the risk of failed pregnancy and maternal neglect.

# publications[].label
Post-implantation exposure to high dose nicotine leads to somatic and brain growth restrictions.

# publications[].label
Long-term effects of neonatal alcohol exposure on photic reentrainment and phase-shifting responses of the activity rhythm in adult rats.

# publications[].label
Fetal and maternal sheep hypothalamus pituitary adrenal axis responses to chronic binge ethanol exposure during the third trimester equivalent.

# publications[].label
Evaluating the Impact of Pre-Matriculation Instruction on Academic Performance in the Anatomical and Physiological Sciences

# publications[].label
Suppression and epigenetic regulation of MiR-9 contributes to ethanol teratology: evidence from zebrafish and murine fetal neural stem cell models.

# publications[].label
Neonatal alcohol exposure differentially alters clock gene oscillations within the suprachiasmatic nucleus, cerebellum, and liver of adult rats.

# publications[].label
Neonatal alcohol exposure alters anatomical components of the pathway for photic entrainment in adult rats.

# publications[].label
Effects of nicotine exposure during prenatal or perinatal period on cell numbers in adult rat hippocampus and cerebellum: a stereology study.

# publications[].label
All three trimester binge alcohol exposure reduces ovine fetal hippocampal CA1, but not CA3 pyramidal and granule cells

# publications[].label
Chronic ethanol increases fetal cerebral blood flow specific to the ethanol-sensitive cerebellum under normoxaemic, hypercapnic and acidaemic conditions: ovine model.

# publications[].label
Effects of All Three Trimester in Utero Binge Ethanol Exposure on the Fetal Hippocampal Formation: Ovine Model

# publications[].label
Acid sensitive channel inhibition prevents ethanol-induced fetal cerebellar injury

# publications[].label
Effects of preconception nicotine exposure on estrous cycle and fetal development in rats

# publications[].label
Antioxidant pretreatment does not ameliorate alcohol-induced Purkinje cell loss in the developing rat cerebellum.

# publications[].label
Changes in blood alcohol levels as a function of alcohol concentration and repeated alcohol exposure in adult female rats: potential risk factors for alcohol-induced fetal brain injury.

# publications[].label
Amphetamine treatment during early postnatal development transiently restricts somatic growth.

# publications[].label
Zinc supplementation does not attenuate alcohol-induced cerebellar Purkinje cell loss during the brain growth spurt period.

# publications[].label
Cocaethylene exposure during the brain growth spurt period: brain growth restrictions and neurochemistry studies.

# publications[].label
Different patterns of regional Purkinje cell loss in the cerebellar vermis as a function of the timing of prenatal ethanol exposure in an ovine model.

# publications[].label
Prenatal alcohol exposure and blood-brain barrier permeability of adult rats at various ages

# publications[].label
Effect of prenatal or perinatal nicotine exposure on neonatal thyroid status and offspring growth in rats.

# publications[].label
Antioxidants do not ameliorate alcohol-induced Purkinje cell loss in the lobule I of the developing cerebellar vermis

# publications[].label
EFFECTS OF EARLY EMBRYONIC ALCOHOL EXPOSURE IN ZEBRAFISH ON SPECIFIC MIRNA PROFILES

# publications[].label
Interactive effect of alcohol and nicotine on developing cerebellum: an investigation of the temporal pattern of alcohol and nicotine administration.

# publications[].label
Nicotine decreases blood alcohol concentration in neonatal rats.

# publications[].label
Alcohol-mediated Purkinje cell loss in the absence of hypoxemia during the third trimester in an ovine model system.

# publications[].label
Evaluating the Impact of Pre-Matriculation Instruction on Academic Performance in the Anatomical and Physiological Sciences

# publications[].label
Neonatal alcohol exposure permanently disrupts the circadian properties and photic entrainment of the activity rhythm in adult rats.

# publications[].label
Fetal alcohol exposure and temporal vulnerability regional differences in alcohol-induced microencephaly as a function of the timing of binge-like alcohol exposure during rat brain development.

# publications[].label
Maternal adrenocorticotropin, cortisol, and thyroid hormone responses to all three-trimester equivalent repeated binge alcohol exposure: ovine model.

# publications[].label
Neonatal alcohol exposure alters the distribution of retinohypothalamic tract (RHT) fibers innervating the adult rat suprachiasmatic nucleus (SCN).

# publications[].label
TEMPORAL AND SPATIAL VULNERABILITY OF OVINE FETAL CEREBELLAR PURKINJE CELLS TO CHRONIC BINGE ALCOHOL EXPOSURE

# publications[].label
Reproductive viability is affected by prenatal nicotine exposure in Sprague-Dawley rats.

# publications[].label
Nicotine decreases blood alcohol concentrations in adult rats: a phenomenon potentially related to gastric function.

# publications[].label
Estimation of neuronal numbers in rat hippocampus following neonatal amphetamine exposure: a stereology study.

# publications[].label
Phosphate-enhanced cytotoxicity of zinc oxide nanoparticles and agglomerates.

# publications[].label
Brain high energy phosphate responses to alcohol exposure in neonatal rats: an in vivo 31P-NMR study.

# publications[].label
Evaluating the Impact of Pre-Matriculation Instruction on Academic Performance in the Anatomical and Physiological Sciences

# publications[].label
The interactive effect of alcohol and nicotine on developing cerebellum: An investigation of the temporal pattern of alcohol and nicotine administration

# publications[].label
The interactive effect of alcohol and nicotine on NGF-treated pheochromocytoma cells.

# publications[].label
Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study.

# publications[].label
Alcohol-induced brain damage during development: Potential risk factors

# publications[].label
Alcohol-induced brain growth restrictions (microencephaly) were not affected by concurrent exposure to cocaine during the brain growth spurt.

# publications[].label
Third trimester binge ethanol exposure results in fetal hypercapnea and acidemia but not hypoxemia in pregnant sheep.

# publications[].label
Cocaine exposure during the brain growth spurt failed to produce cerebellar Purkinje cell loss in rat pups.

# publications[].label
Prenatal nicotine exposure does not cause Purkinje cell loss in the developing rat cerebellar vermis.

# publications[].label
Long-term nicotine exposure reduces Purkinje cell number in the adult rat cerebellar vermis.

# publications[].label
The role of cortisol in chronic binge alcohol-induced cerebellar injury: Ovine model.

# publications[].label
Early postnatal alcohol exposure produced long-term deficits in brain weight, but not the number of neurons in the locus coeruleus.

# publications[].label
Effects of alcohol and nicotine on developing olfactory bulb: loss of mitral cells and alterations in neurotransmitter levels.

# publications[].label
Developmental alcohol exposure disrupts circadian regulation of BDNF in the rat suprachiasmatic nucleus.

# publications[].label
Acid-sensitive channel inhibition prevents fetal alcohol spectrum disorders cerebellar Purkinje cell loss.

# publications[].label
Cocaine exposure during the brain growth spurt: studies of neonatal survival, somatic growth, and brain development.

# publications[].label
Fetal and maternal thyroid hormone responses to ethanol exposure during the third trimester equivalent of gestation in sheep.

# publications[].label
DYSREGULATION OF MIR-9 AND ITS TARGETS FGFR1, FOXP2, AND MECP2 IN THE ZEBRAFISH (D-RERIO) EMBRYO FOLLOWING ETHANOL EXPOSURE

# publications[].label
Role of hypercapnea and acidemia in alcohol mediated fetal cerbellar injury

# publications[].label
Acute hemodynamic, pituitary, and adrenocortical responses to alcohol in adult female sheep.

# publications[].label
Combination drug use and risk for fetal harm.

# publications[].label
Co-exposure of alcohol and nicotine causes a synergistic decrease in pheochromocytoma (PC12) cell numbers over time

# publications[].label
Temporal vulnerability of fetal cerebellar Purkinje cells to chronic binge alcohol exposure: ovine model.

# publications[].label
Neonatal alcohol exposure increases malondialdehyde (MDA) and glutathione (GSH) levels in the developing cerebellum.

# publications[].label
All three trimester binge alcohol exposure causes fetal cerebellar purkinje cell loss in the presence of maternal hypercapnea, acidemia, and normoxemia: ovine model.

# publications[].label
Cocaine-induced somatic growth deficit during the brain growth spurt is prevented by artificial-rearing.

# publications[].label
Antioxidants do not protect against developmental alcohol-induced malondialdehyde (MDA) production in the developing rat cerebellum

# publications[].label
DYSREGULATION OF DEVELOPMENTAL MIR-9 AND ITS TARGET GENES IN THE ZEBRAFISH (D. RERIO) EMBRYO FOLLOWING ETHANOL EXPOSURE

# publications[].label
Developmental alcohol and circadian clock function

# publications[].label
Developmental alcohol exposure disrupts clock gene rhythms in the rat SCN and cerebellum.

# publications[].label
Alcohol-induced inhibition of cocaine metabolism and the formation of cocaethylene in neonatal rats.

# publications[].label
Chronic continuous nicotine exposure during periadolescence does not increase ethanol intake during adulthood in rats.

# publications[].label
Ontogenetic differences in the expression of conditioned stimulus conditioning: effects of retention interval.

# publications[].label
The timing of alcohol consumption during pregnancy and fetal alcohol-induced brain damage

# publications[].label
The role of cortisol in chronic binge alcohol-induced fetal cerebellar injury in sheep

# publications[].label
Acute melatonin and para-chloroamphetamine interactions on pineal, brain and serum serotonin levels as well as stress hormone levels.

# publications[].label
Ethanol attenuates lactate production in hypoxic postnatal day 4 rat cerebella.

# publications[].label
Developmental alcohol exposure alters light-induced phase shifts of the circadian activity rhythm in rats.

# publications[].label
Activation of cell cycle activity by alcohol is antagonized by the presence of nicotine in NGF-treated pheochromocytoma (PC12)cells

# publications[].label
Melatonin (an antioxidant) does not ameliorate alcohol-induced Purkinje cell loss in the developing cerebellum.

# researcherOn[].label
Estrogens, Ovarian Aging and Calcium Channel Modulation

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Prenatal microRNA Neuro-Therapeutics for Fetal Alcohol Exposure

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute on Alcohol Abuse and Alcoholism (NIAAA)

# streetAddress
Texas A&M Health Science Center; Academic Affairs Com; 1114 TAMUS

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine

# schools[]
Texas A&M University Naresh K. Vashisht College of Medicine