# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# keywords[]
Squamous Cell Carcinoma Of Head And Neck

# keywords[]
Pol1 Transcription Initiation Complex Proteins

# keywords[]
Receptor, Fibroblast Growth Factor, Type 4

# publications[].label
A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells.

# publications[].label
Pluripotency Versus Self-Renewal of ES Cells: Two Sides of the Same Coin or More?

# publications[].label
Nucleostemin inhibits TRF1 dimerization and shortens its dynamic association with the telomere.

# publications[].label
Designing a Mucoadhesive ChemoPatch to Ablate Oral Dysplasia for Cancer Prevention.

# publications[].label
Cell contact regulates fate choice by cortical stem cells.

# publications[].label
Pharmacokinetic Model Analysis of Supralingual, Oral and Intravenous Deliveries of Mycophenolic Acid.

# publications[].label
Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability.

# publications[].label
Using a eukaryotic GST fusion vector for proteins difficult to express in E. coli.

# publications[].label
Fibroblast growth factor 2 negatively regulates the induction of neuronal progenitors from neural stem cells.

# publications[].label
A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration.

# publications[].label
Grafted Neural Stem Cells Show Lesion-Specific Migration in Radiation-Injured Rat Brains.

# publications[].label
Sex and Race-Related DNA Methylation Changes in Hepatocellular Carcinoma.

# publications[].label
A molecular view of stem cell and cancer cell self-renewal.

# publications[].label
BAC transgenic expression efficiency: bicistronic versus ATG-fusion strategies.

# publications[].label
Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?

# publications[].label
Genes encoding components of the olfactory signal transduction cascade contain a DNA binding site that may direct neuronal expression.

# publications[].label
Nucleostemin Modulates Outcomes of Hepatocellular Carcinoma via a Tumor Adaptive Mechanism to Genomic Stress.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Determination of Oxaliplatin by a UHPLC-MS/MS Method: Application to Pharmacokinetics and Tongue Tissue Distribution Studies in Rats.

# publications[].label
Determination and validation of mycophenolic acid by a UPLC-MS/MS method: Applications to pharmacokinetics and tongue tissue distribution studies in rats.

# publications[].label
Nucleostemin upregulation and STAT3 activation as early events in oral epithelial dysplasia progression to squamous cell carcinoma.

# publications[].label
Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1.

# publications[].label
GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding.

# publications[].label
Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively.

# publications[].label
GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest.

# publications[].label
Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm.

# publications[].label
IMPDH Inhibition Decreases TERT Expression and Synergizes the Cytotoxic Effect of Chemotherapeutic Agents in Glioblastoma Cells.

# publications[].label
Human nuclease/helicase DNA2 alleviates replication stress by promoting DNA end resection.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin.

# publications[].label
Connecting the nucleolus to the cell cycle and human disease.

# publications[].label
Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress.

# publications[].label
Nucleolar modulation of TRF1: a dynamic way to regulate telomere and cell cycle by nucleostemin and GNL3L.

# publications[].label
p53-guided response to nucleostemin loss in normal versus cancer cells.

# publications[].label
Efficient Gene Knockdown in the Liver via Intrasplenic Injection of Adeno-Associated Virus Serotype 8 (AAV8)-Delivered Small Hairpin RNA.

# publications[].label
Turning a new page on nucleostemin and self-renewal.

# publications[].label
Expression of the iron transporter ferroportin in synaptic vesicles and the blood-brain barrier.

# publications[].label
On the Cutting Edge of Oral Cancer Prevention: Finding Risk-Predictive Markers in Precancerous Lesions by Longitudinal Studies.

# publications[].label
Nucleostemin: a latecomer with new tricks.

# publications[].label
Nucleolar trafficking of nucleostemin family proteins: common versus protein-specific mechanisms.

# publications[].label
Plasticity, niches, and the use of stem cells.

# publications[].label
Epigenome-wide analysis of aging effects on liver regeneration.

# publications[].label
Nucleoplasmic mobilization of nucleostemin stabilizes MDM2 and promotes G2-M progression and cell survival.

# publications[].label
Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein Roaz.

# publications[].label
Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum.

# publications[].label
The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.

# publications[].label
DNA Methylation and Target Gene Expression in Fatty Liver Progression From Simple Steatosis to Advanced Fibrosis.

# publications[].label
Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Transcriptional control of a stem cell factor nucleostemin in liver regeneration and aging.

# publications[].label
Tumor-initiating function of nucleostemin-enriched mammary tumor cells.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development.

# publications[].label
Creating a graft-friendly environment for stem cells in diseased brains.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Nucleostemin reveals a dichotomous nature of genome maintenance in mammary tumor progression.

# publications[].label
GTP depletion synergizes the anti-proliferative activity of chemotherapeutic agents in a cell type-dependent manner.

# publications[].label
GNL3L stabilizes the TRF1 complex and promotes mitotic transition.

# publications[].label
In search of nonribosomal nucleolar protein function and regulation.

# researcherOn[].label
Genome-Wide DNA Methylation Markers for Predicting the Risk of Liver Cancer in Non- Alcoholic Fatty Livers

# researcherOn[].awardedBy.label
Cancer Prevention and Research Institute of Texas - (Austin, Texas, United States)

# researcherOn[].label
Nucleostemin: A New Tumor Addictive Mechanism, Outcome Predictor, and Therapeutic Target for Hepatocellular Carcinoma

# researcherOn[].awardedBy.label
Cancer Prevention and Research Institute of Texas - (Austin, Texas, United States)

# researcherOn[].label
Chemoablation of high-risk oral premalignant lesions for sustained cancer prevention

# researcherOn[].awardedBy.label
Cancer Prevention and Research Institute of Texas - (Austin, Texas, United States)

# researcherOn[].label
Aging Effect on Genome Maintenance during Hepatocyte Regeneration

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Role of Nucleostemin in Conferring The Drug Resistance of Hepatocellular Carcinoma

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# streetAddress
Texas A&M Health Science Center; Ibt Center For Translational Cancer Research; 1201 TAMUS

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine

# schools[]
Texas A&M University Naresh K. Vashisht College of Medicine