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Middle East Respiratory Syndrome Coronavirus

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Intracellular Signaling Peptides And Proteins

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5 Development Of Treatments And Therapeutic Interventions

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2.2 Factors Relating To The Physical Environment

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5 Development Of Treatments And Therapeutic Interventions

# educationAndTraining[].organization.label
University of Toledo - (Toledo, Ohio, United States)

# educationAndTraining[].organization.label
Scripps Research Institute - (San Diego, California, United States)

# educationAndTraining[].organization.label
University of Reading - (Reading, United Kingdom)

# publications[].label
Proteomics Analysis Unravels the Functional Repertoire of Coronavirus Nonstructural Protein 3

# publications[].label
The proteome of the infectious bronchitis virus Beau-R virion.

# publications[].label
Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers.

# publications[].label
Untangling membrane rearrangement in the nidovirales.

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Atlas of coronavirus replicase structure.

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Nuclear Magnetic Resonance Structure of the N-Terminal Domain of Nonstructural Protein 3 from the Severe Acute Respiratory Syndrome Coronavirus

# publications[].label
Functional and structural proteomics of SARS: defining a rational response to emerging diseases

# publications[].publisher
International Union of Crystallography (IUCr)

# publications[].label
Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch

# publications[].label
Synthesis and antiviral activity of novel spirocyclic nucleosides

# publications[].label
Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2.

# publications[].label
Quantum Optical Immunoassay: Upconversion Nanoparticle-based Neutralizing Assay for COVID-19

# publications[].label
Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy.

# publications[].label
Isolation, Characterisation and Experimental Evolution of Phage that Infect the Horse Chestnut Tree Pathogen, Pseudomonas syringae pv. aesculi.

# publications[].label
Antiviral Effects of Antisense Morpholino Oligomers in Murine Coronavirus Infection Models

# publications[].label
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2.

# publications[].label
Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers.

# publications[].label
Severe acute respiratory syndrome-related coronavirus: The species and its viruses  a statement of the Coronavirus Study Group

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DETECTION OF TOBACCO MOSAIC TOBAMOVIRUS IN CIGARETTES THROUGH RT-PCR

# publications[].label
Direct observation of membrane insertion by enveloped virus matrix proteins by phosphate displacement.

# publications[].label
Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay.

# publications[].label
Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors.

# publications[].label
How the double spherules of infectious bronchitis virus impact our understanding of RNA virus replicative organelles.

# publications[].label
Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1''-phosphate dephosphorylation by a conserved domain of nsP3.

# publications[].label
Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth.

# publications[].label
Inhibition of Cytosolic Phospholipase A2 Impairs an Early Step of Coronavirus Replication in Cell Culture.

# publications[].label
Does form meet function in the coronavirus replicative organelle?

# publications[].label
A Fusion Peptide in the Spike Protein of MERS Coronavirus.

# publications[].label
Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions.

# publications[].label
An Azapeptide Platform in Conjunction with Covalent Warheads to Uncover High-Potency Inhibitors for SARS-CoV-2 Main Protease.

# publications[].label
Quantum optical immunoassay: upconversion nanoparticle-based neutralizing assay for COVID-19.

# publications[].label
New insights on the role of paired membrane structures in coronavirus replication.

# publications[].label
Bacteriophages as promising agents for the biological control of Moko disease (Ralstonia solanacearum) of banana

# publications[].label
Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity.

# publications[].label
A fiber optic-nanophotonic approach to the detection of antibodies and viral particles of COVID-19

# publications[].label
Purification of coronavirus virions for Cryo-EM and proteomic analysis.

# publications[].label
Complementarity in the supramolecular design of arenaviruses and retroviruses revealed by electron cryomicroscopy and image analysis.

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ChemInform Abstract: Synthesis and Antiviral Properties of Spirocyclic [1,2,3]Triazolooxazine Nucleosides.

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Identification and Characterization of a Ribose 2'-O-Methyltransferase Encoded by the Ronivirus Branch of Nidovirales.

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ICTV Virus Taxonomy Profile: Coronaviridae 2023.

# publications[].label
Crystal structure of nonstructural protein 10 from the severe acute respiratory syndrome coronavirus reveals a novel fold with two zinc-binding motifs.

# publications[].label
Use of an infectious bronchitis virus D-RNA as an RNA vector.

# publications[].label
Ultrastructure of SARS-CoV, FIPV, and MHV revealed by electron cryomicroscopy.

# publications[].label
Rapid identification of emerging pathogens: coronavirus.

# publications[].publisher
Centers for Disease Control and Prevention (CDC)

# publications[].label
Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles.

# publications[].label
Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles.

# publications[].label
Description and initial characterization of metatranscriptomic nidovirus-like genomes from the proposed new family Abyssoviridae, and from a sister group to the Coronavirinae, the proposed genus Alphaletovirus.

# publications[].label
Case Report: Paucisymptomatic College-Age Population as a Reservoir for Potentially Neutralization-Resistant Severe Acute Respiratory Syndrome Coronavirus 2 Variants.

# publications[].publisher
American Society of Tropical Medicine and Hygiene

# publications[].label
Genomic Characterisation of Mushroom Pathogenic Pseudomonads and Their Interaction with Bacteriophages.

# publications[].label
Purification and electron cryomicroscopy of coronavirus particles.

# publications[].label
SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding.

# publications[].label
Use of defective RNAs containing reporter genes to investigate targeted recombination for avian infectious bronchitis virus.

# publications[].label
Supramolecular Architecture of the Coronavirus Particle

# publications[].label
New CLEM Method to Reveal Ultrastructural Reorganization in the Host Cell during Coronavirus Infection

# publications[].label
Mapping the Landscape of the Lymphocytic Choriomeningitis Virus Stable Signal Peptide Reveals Novel Functional Domains

# publications[].label
A structural analysis of M protein in coronavirus assembly and morphology.

# publications[].label
Ribonucleocapsid Formation of Severe Acute Respiratory Syndrome Coronavirus through Molecular Action of the N-Terminal Domain of N Protein

# publications[].label
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

# publications[].label
Infectious Bronchitis Virus Nonstructural Protein 4 Alone Induces Membrane Pairing.

# publications[].label
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.

# publications[].label
Supramolecular Architecture of the Coronavirus Particle.

# publications[].label
Nuclear Magnetic Resonance Structure Shows that the Severe Acute Respiratory Syndrome Coronavirus-Unique Domain Contains a Macrodomain Fold

# publications[].label
Azapeptides with unique covalent warheads as SARS-CoV-2 main protease inhibitors.

# publications[].label
Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.

# publications[].label
Identification of a Membrane Binding Peptide in the Envelope Protein of MHV Coronavirus.

# publications[].label
Improving Virus Taxonomy by Recontextualizing Sequence-Based Classification with Biologically Relevant Data: the Case of the Alphacoronavirus 1 Species.

# publications[].label
SARS Coronavirus Unique Domain: Three-Domain Molecular Architecture in Solution and RNA Binding

# publications[].label
Bioinformatics analysis for L polymerase homology of arenaviruses

# publications[].label
Nuclear Magnetic Resonance Structure of the Nucleic Acid-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 3

# publications[].label
Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7.

# publications[].label
Arenavirus budding resulting from viral-protein-associated cell membrane curvature.

# publications[].label
Receptor-Binding-Motif-Targeted Sanger Sequencing: a Quick and Cost-Effective Strategy for Molecular Surveillance of SARS-CoV-2 Variants.

# publications[].label
Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease.

# inTheNews[].label
Houston-area COVID-19 outbreak — including delta variant cases — should be a wake-up call for Texans, health expert warns

# inTheNews[].label
Scientists battle over the ultimate origin story: Where did the coronavirus come from?

# inTheNews[].label
COVID Help Desk: Is it possible to see how vaccines are lowering the coronavirus case rate?

# inTheNews[].label
What You Need To Know About The Delta COVID-19 Variant

# inTheNews[].label
Experts Predict What The Next COVID-19 Variants Will Be Like

# inTheNews[].label
Rising share of coronavirus tests coming back positive in Texas fuels fears of another wave

# inTheNews[].label
Houston-area COVID-19 outbreak — including Delta variant cases — should be a wake-up call for Texans, health expert warns

# inTheNews[].label
Delta variant dominant in US, makes up more than half of Covid-19 cases