# positions[].organizations[].parent[].label
College of Veterinary Medicine and Biomedical Sciences

# positions[].organizations[].parent[].label
School of Veterinary Medicine and Biomedical Sciences

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Interferon-Stimulated Gene Factor 3, Gamma Subunit

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Mechanistic Target Of Rapamycin Complex 1

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Interferon-Stimulated Gene Factor 3, Gamma Subunit

# keywords[]
Insulin-like Growth Factor Binding Protein 3

# keywords[]
Insulin-like Growth Factor Binding Protein 1

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Oxidoreductases Acting On Ch-nh Group Donors

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Rapamycin-insensitive Companion Of Mtor Protein

# educationAndTraining[].organization.label
University of Wyoming - (Laramie, Wyoming, United States)

# awardsAndHonors[].label
Association of Former Students University-Level Distinguished Achievement Award, The

# awardsAndHonors[].label
Association of Former Students College-Level Teaching Distinguished Achievement Award, The

# awardsAndHonors[].label
Outstanding Graduate Student Mentor Award

# awardsAndHonors[].label
Outstanding Graduate Student Mentor Award

# awardsAndHonors[].label
Enhancing Development and Generating Excellence in Scholarship (EDGES) Fellow

# publications[].label
Interferon-tau (IFN tau) regulation of IFN-stimulated gene expression in cell lines lacking specific IFN-signaling components

# publications[].label
Effects of the estrous cycle, pregnancy, and interferon tau on 2',5'-oligoadenylate synthetase expression in the ovine uterus.

# publications[].label
Select nutrients in the ovine uterine lumen. VII. Effects of arginine, leucine, glutamine, and glucose on trophectoderm cell signaling, proliferation, and migration.

# publications[].label
Immunization of mice against a synthetic N-terminal extracellular domain gonadotropin-releasing hormone receptor peptide: evidence for a direct uterine effect.

# publications[].label
Interferon-tau and progesterone regulate ubiquitin cross-reactive protein expression in the ovine uterus.

# publications[].label
Dietary supplementation with 0.8% L-arginine between days 0 and 25 of gestation reduces litter size in gilts.

# publications[].label
Cellular events during ovine implantation and impact for gestation.

# publications[].publisher
Colegio Brasileiro de Reproducao Animal - CBRA

# publications[].label
Effects of long-term progesterone on developmental and functional aspects of porcine uterine epithelia and vasculature: progesterone alone does not support development of uterine glands comparable to that of pregnancy.

# publications[].label
The sphingosine 1-phosphate (S1P) signaling pathway is regulated during pregnancy in sheep.

# publications[].label
Keratinocyte growth factor: expression by endometrial epithelia of the porcine uterus.

# publications[].label
Proline and hydroxyproline metabolism: implications for animal and human nutrition.

# publications[].label
Roles of Stat1, Stat2, and interferon regulatory factor-9 (IRF-9) in interferon tau regulation of IRF-1.

# publications[].label
Glycosylation dependent cell adhesion molecule 1-like protein and L-selectin expression in sheep interplacentomal and placentomal endometrium.

# publications[].label
Functional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep.

# publications[].label
Placental Proteomics Reveal Insights into Fetal Alcohol Spectrum Disorders.

# publications[].label
Select nutrients in the ovine uterine lumen. ii. glucose transporters in the uterus and peri-implantation conceptuses.

# publications[].label
Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells.

# publications[].label
Secreted phosphoprotein 1 (osteopontin) is expressed by stromal macrophages in cyclic and pregnant endometrium of mice, but is induced by estrogen in luminal epithelium during conceptus attachment for implantation.

# publications[].label
Impacts of maternal dietary protein intake on fetal survival, growth, and development.

# publications[].label
Osteopontin expression in uterine stroma indicates a decidualization-like differentiation during ovine pregnancy.

# publications[].label
Insulin-like growth factor II activates phosphatidylinositol 3-kinase-protooncogenic protein kinase 1 and mitogen-activated protein kinase cell Signaling pathways, and stimulates migration of ovine trophectoderm cells.

# publications[].label
Osteopontin: roles in implantation and placentation.

# publications[].label
Amino acids and conceptus development during the peri-implantation period of pregnancy.

# publications[].label
Identification of appropriate reference genes for qPCR analyses of placental expression of SLC7A3 and induction of SLC5A1 in porcine endometrium.

# publications[].label
Complex induction of bovine uterine proteins by interferon-tau.

# publications[].label
Transient ubiquitin cross-reactive protein gene expression in the bovine endometrium.

# publications[].label
Proteome Differences in Placenta and Endometrium between Normal and Intrauterine Growth Restricted Pig Fetuses.

# publications[].label
Select nutrients in the ovine uterine lumen. IV. Expression of neutral and acidic amino acid transporters in ovine uteri and peri-implantation conceptuses.

# publications[].label
Implantation mechanisms: insights from the sheep.

# publications[].label
Uterine histotroph and conceptus development: select nutrients and secreted phosphoprotein 1 affect mechanistic target of rapamycin cell signaling in ewes.

# publications[].label
IFPA Meeting 2010 Workshop Report I: Immunology; ion transport; epigenetics; vascular reactivity; epitheliochorial placentation; proteomics.

# publications[].label
Select nutrients in the uterine lumen of sheep and pigs affect conceptus development.

# publications[].label
The influence of estrogen on hepatobiliary osteopontin (SPP1) expression in a female rodent model of alcoholic steatohepatitis.

# publications[].label
Topdressing Turf with Composted Manure Improves Soil Quality and Protects Water Quality

# publications[].label
Ovine osteopontin: I. Cloning and expression of messenger ribonucleic acid in the uterus during the periimplantation period.

# publications[].label
Mechanistic mammalian target of rapamycin (MTOR) cell signaling: effects of select nutrients and secreted phosphoprotein 1 on development of mammalian conceptuses.

# publications[].label
Steroid regulation of cell specific secreted phosphoprotein 1 (osteopontin) expression in the pregnant porcine uterus.

# publications[].label
BOARD-INVITED REVIEW: Arginine nutrition and metabolism in growing, gestating, and lactating swine.

# publications[].label
Expression of the interferon tau inducible ubiquitin cross-reactive protein in the ovine uterus.

# publications[].label
Fructose Synthesis and Transport at the Uterine-Placental Interface of Pigs: Cell-Specific Localization of SLC2A5, SLC2A8, and Components of the Polyol Pathway.

# publications[].label
Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses.

# publications[].label
ITGAV (alpha v integrins) bind SPP1 (osteopontin) to support trophoblast cell adhesion.

# publications[].label
Maternal recognition of pregnancy signal or endocrine disruptor: the two faces of oestrogen during establishment of pregnancy in the pig.

# publications[].label
Interferon stimulated gene 15 conjugates to endometrial cytosolic proteins and is expressed at the uterine-placental interface throughout pregnancy in sheep.

# publications[].label
Pig conceptuses increase uterine interferon-regulatory factor 1 (IRF1), but restrict expression to stroma through estrogen-induced IRF2 in luminal epithelium.

# publications[].label
Uterine histotroph and conceptus development. I. cooperative effects of arginine and secreted phosphoprotein 1 on proliferation of ovine trophectoderm cells via activation of the PDK1-Akt/PKB-TSC2-MTORC1 signaling cascade.

# publications[].label
Induction of apoptotic or lytic death in an ovarian adenocarcinoma cell line by antibodies generated against a synthetic N-terminal extracellular domain gonadotropin-releasing hormone receptor peptide.

# publications[].label
Prolactin receptor and uterine milk protein expression in the ovine endometrium during the estrous cycle and pregnancy.

# publications[].label
Evidence that absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation.

# publications[].label
Interferon-tau activates multiple signal transducer and activator of transcription proteins and has complex effects on interferon-responsive gene transcription in ovine endometrial epithelial cells.

# publications[].label
Role of the cytoskeleton in formation and maintenance of angiogenic sprouts.

# publications[].label
Glutamine synthesis in the developing porcine placenta.

# publications[].label
Important roles for the arginine family of amino acids in swine nutrition and production

# publications[].label
Select nutrients and glucose transporters in pig uteri and conceptuses.

# publications[].label
Cloning of the ovine estrogen receptor-alpha promoter and functional regulation by ovine interferon-tau

# publications[].label
Uterine stromal cell differentiation in non-decidualizing species

# publications[].label
Embryo production and possible species preservation by nuclear transfer of somatic cells isolated from bovine semen.

# publications[].label
Bovine interferon-tau stimulates the Janus kinase-signal transducer and activator of transcription pathway in bovine endometrial epithelial cells.

# publications[].label
Differential effects of intrauterine and subcutaneous administration of recombinant ovine interferon tau on the endometrium of cyclic ewes.

# publications[].label
Decline in sialic acid composition of cellular membranes isolated from ovine corpora lutea during prostaglandin-induced luteolysis: apparent independence of autoimmune recognition.

# publications[].label
Technical note: Isolation and characterization of porcine mammary epithelial cells.

# publications[].label
Interferon-tau (IFNtau) regulation of IFN-stimulated gene expression in cell lines lacking specific IFN-signaling components.

# publications[].label
Endometrial ISG17 mRNA and a related mRNA are induced by interferon-tau and localized to glandular epithelial and stromal cells from pregnant cows.

# publications[].label
The temporal expression of osteopontin (SPP-1) in the rodent model of alcoholic steatohepatitis: a potential biomarker.

# publications[].label
Pregnancy recognition signals in mammals: the roles of interferons and estrogens

# publications[].publisher
Colegio Brasileiro de Reproducao Animal - CBRA

# publications[].label
Intrauterine growth retardation in livestock: Implications, mechanisms and solutions

# publications[].label
Baculovirus-insect cell production of bioactive choriogonadotropin-immunoglobulin G heavy-chain fusion proteins in sheep.

# publications[].label
Origin and ontogeny of mammalian ovarian neurons.

# publications[].label
Functional amino acids in the development of the pig placenta.

# publications[].label
Interferons and progesterone for establishment and maintenance of pregnancy: interactions among novel cell signaling pathways.

# publications[].label
Environmental factors affecting pregnancy: endocrine disrupters, nutrients and metabolic pathways.

# publications[].label
Functional analysis of autocrine and paracrine signalling at the uterine-conceptus interface in pigs.

# publications[].label
Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal-conceptus interface and uterine wall during ovine pregnancy.

# publications[].label
Temporal and spatial associations of oestrogen receptor alpha and progesterone receptor in the endometrium of cyclic and early pregnant mares.

# publications[].label
Developmental biology of uterine glands.

# publications[].label
Insulin-like growth factor binding protein-1 in the ruminant uterus: potential endometrial marker and regulator of conceptus elongation.

# publications[].label
Select nutrients and their effects on conceptus development in mammals.

# publications[].label
Pig conceptuses secrete estrogen and interferons to differentially regulate uterine STAT1 in a temporal and cell type-specific manner.

# publications[].label
Regulation of expression of fibroblast growth factor 7 in the pig uterus by progesterone and estradiol.

# publications[].label
Monocyte chemotactic protein-1 and -2 messenger ribonucleic acids in the ovine uterus: regulation by pregnancy, progesterone, and interferon-tau.

# publications[].label
Ovine osteopontin: II. Osteopontin and alpha(v)beta(3) integrin expression in the uterus and conceptus during the periimplantation period.

# publications[].label
Stanniocalcin 1 is a luminal epithelial marker for implantation in pigs regulated by progesterone and estradiol.

# publications[].label
Adverse organogenesis and predisposed long-term metabolic syndrome from prenatal exposure to fine particulate matter.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Isolation, immortalization, and initial characterization of uterine cell lines: an in vitro model system for the porcine uterus.

# publications[].label
Ovine placental lactogen specifically binds to endometrial glands of the ovine uterus.

# publications[].label
The Interferon Stimulated Genes (ISG) 17 and Mx have different temporal and spatial expression in the ovine uterus suggesting more complex regulation of the Mx gene.

# publications[].label
Proline metabolism in the conceptus: implications for fetal growth and development.

# publications[].label
Evaluation of culture systems for attachment and proliferation of epithelial cells cultured from ovine semen.

# publications[].label
Conceptus signals for establishment and maintenance of pregnancy.

# publications[].label
Select nutrients in the ovine uterine lumen. V. Nitric oxide synthase, GTP cyclohydrolase, and ornithine decarboxylase in ovine uteri and peri-implantation conceptuses.

# publications[].label
Effects of protease inhibitors and antioxidants on In vitro survival of porcine primordial germ cells.

# publications[].label
Conceptus-uterus interactions in pigs: endometrial gene expression in response to estrogens and interferons from conceptuses.

# publications[].label
Muc-1, integrin, and osteopontin expression during the implantation cascade in sheep.

# publications[].label
Expression of the uterine Mx protein in cyclic and pregnant cows, gilts, and mares.

# publications[].label
Impacts of amino acid nutrition on pregnancy outcome in pigs: mechanisms and implications for swine production.

# publications[].label
The Early Stages of Implantation and Placentation in the Pig.

# publications[].label
Pregnancy and interferon-tau induce conjugation of bovine ubiquitin cross-reactive protein to cytosolic uterine proteins.

# publications[].label
Integrin activation in bovine placentomes and in caruncular epithelial cells isolated from pregnant cows.

# publications[].label
Novel pathways for implantation and establishment and maintenance of pregnancy in mammals.

# publications[].label
Integrins and extracellular matrix proteins at the maternal-fetal interface in domestic animals.

# publications[].label
Uterine MHC class I molecules and beta 2-microglobulin are regulated by progesterone and conceptus interferons during pig pregnancy.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Development and characterization of immortalized ovine endometrial cell lines.

# publications[].label
Select nutrients and their associated transporters are increased in the ovine uterus following early progesterone administration.

# publications[].label
Temporal and spatial expression of aquaporins 1, 5, 8, and 9: Potential transport of water across the endometrium and chorioallantois of pigs.

# publications[].label
Keratinocyte growth factor is up-regulated by estrogen in the porcine uterine endometrium and functions in trophectoderm cell proliferation and differentiation

# publications[].label
Immunohistochemical Examination of Trophoblast Syncytialization during Early Placentation in Sheep.

# publications[].label
Dietary supplementation with L-arginine between days 14 and 25 of gestation enhances embryonic development and survival in gilts.

# publications[].label
Select nutrients in the ovine uterine lumen. VIII. Arginine stimulates proliferation of ovine trophectoderm cells through MTOR-RPS6K-RPS6 signaling cascade and synthesis of nitric oxide and polyamines.

# publications[].label
Aqueous leaching of an industrial geopolymer

# publications[].label
Progesterone and placentation increase secreted phosphoprotein one (SPP1 or osteopontin) in uterine glands and stroma for histotrophic and hematotrophic support of ovine pregnancy.

# publications[].label
Flow path influence on an N:P ratio in two headwater streams: A paired watershed study

# publications[].label
Uterine Histotroph and Conceptus Development. II. Arginine and Secreted Phosphoprotein 1 Cooperatively Stimulate Migration and Adhesion of Ovine Trophectoderm Cells via Focal Adhesion-MTORC2 Mediated Cytoskeleton Reorganization.

# publications[].label
Wnt genes in the mouse uterus: potential regulation of implantation.

# publications[].label
Molecular characterization and expression of porcine bone morphogenetic protein receptor-IB in the uterus of cyclic and pregnant gilts.

# publications[].label
Pregnancy and interferon tau regulate major histocompatibility complex class I and beta2-microglobulin expression in the ovine uterus.

# publications[].label
Triennial Growth Symposium: important roles for L-glutamine in swine nutrition and production.

# publications[].label
Analysis of osteopontin at the maternal-placental interface in pigs.

# publications[].label
Comparative organization and gene expression profiles of the porcine pseudoautosomal region.

# publications[].label
A highly efficient method for porcine cloning by nuclear transfer using in vitro-matured oocytes.

# publications[].label
Effects of recombinant ovine interferon tau, placental lactogen, and growth hormone on the ovine uterus.

# publications[].label
Select nutrients in the ovine uterine lumen. I. Amino acids, glucose, and ions in uterine lumenal flushings of cyclic and pregnant ewes.

# publications[].label
Secreted phosphoprotein 1 (SPP1, osteopontin) binds to integrin alpha v beta 6 on porcine trophectoderm cells and integrin alpha v beta 3 on uterine luminal epithelial cells, and promotes trophectoderm cell adhesion and migration.

# publications[].label
Bovine granulocyte chemotactic protein-2 is secreted by the endometrium in response to interferon-tau (IFN-tau).

# publications[].label
Mechanisms for the establishment and maintenance of pregnancy: synergies from scientific collaborations.

# publications[].label
Toward regulation of gonadal function by a synthetic hybrid molecule composed of gonadotropin and Fc fragment of immunoglobulin G.

# publications[].label
Postpartum uterine involution in sheep: histoarchitecture and changes in endometrial gene expression.

# publications[].label
Cathepsin B, cathepsin L, and cystatin C in the porcine uterus and placenta: potential roles in endometrial/placental remodeling and in fluid-phase transport of proteins secreted by uterine epithelia across placental areolae.

# publications[].label
Identification and characterization of glycosylation-dependent cell adhesion molecule 1-like protein expression in the ovine uterus.

# publications[].label
Implantation and Establishment of Pregnancy in the Pig.

# publications[].label
Expression of progesterone receptor in the porcine uterus and placenta throughout gestation: correlation with expression of uteroferrin and osteopontin.

# publications[].label
Progesterone and placental hormone actions on the uterus: insights from domestic animals.

# publications[].label
Select nutrients in the ovine uterine lumen. III. Cationic amino acid transporters in the ovine uterus and peri-implantation conceptuses.

# publications[].label
Transforming growth factor beta (TGFB) signaling is activated during porcine implantation: proposed role for latency-associated peptide interactions with integrins at the conceptus-maternal interface.

# publications[].label
Premature estrogen exposure alters endometrial gene expression to disrupt pregnancy in the pig.

# publications[].label
Interferon regulatory factor-two restricts expression of interferon-stimulated genes to the endometrial stroma and glandular epithelium of the ovine uterus.

# publications[].label
Functional effects of transforming growth factor beta on adhesive properties of porcine trophectoderm.

# publications[].label
Mechanism of action of interferon-tau in the uterus during early pregnancy.

# publications[].label
Effects of long-term progesterone exposure on porcine uterine gene expression: progesterone alone does not induce secreted phosphoprotein 1 (osteopontin) in glandular epithelium.

# publications[].label
Functional amino acids in swine nutrition and production

# publications[].label
Mechanotransduction drives morphogenesis to develop folding during placental development in pigs.

# publications[].label
Polyamine synthesis from proline in the developing porcine placenta.

# publications[].label
Caprine uterine and placental osteopontin expression is distinct among epitheliochorial implanting species.

# publications[].label
Expression of porcine endometrial prostaglandin synthase during the estrous cycle and early pregnancy, and following endocrine disruption of pregnancy.

# publications[].label
Osteopontin is synthesized by uterine glands and a 45-kDa cleavage fragment is localized at the uterine-placental interface throughout ovine pregnancy.

# publications[].label
Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase.

# publications[].label
Progesterone modulation of osteopontin gene expression in the ovine uterus.

# publications[].label
Uterine receptivity to implantation of blastocysts in mammals.

# publications[].label
Select nutrients in the ovine uterine lumen. IX. Differential effects of arginine, leucine, glutamine, and glucose on interferon tau, ornithine decarboxylase, and nitric oxide synthase in the ovine conceptus.

# publications[].label
Arginine, leucine, and glutamine stimulate proliferation of porcine trophectoderm cells through the MTOR-RPS6K-RPS6-EIF4EBP1 signal transduction pathway.

# publications[].label
Osteopontin: a leading candidate adhesion molecule for implantation in pigs and sheep.

# publications[].label
Fetal-maternal interactions during the establishment of pregnancy in ruminants.

# publications[].label
Topdressing Kentucky Bluegrass with Compost Increases Soil Water Content and Improves Turf Quality During Drought

# publications[].label
Galectin 15 (LGALS15): a gene uniquely expressed in the uteri of sheep and goats that functions in trophoblast attachment.

# publications[].label
Development of an in vitro model for bovine placentation: a comparison of the in vivo and in vitro expression of integrins and components of extracellular matrix in bovine placental cells.

# publications[].label
Intrauterine infusion of latency-associated peptide (LAP) during early porcine pregnancy affects conceptus elongation and placental size.

# publications[].label
Integrins and their potential roles in mammalian pregnancy.

# publications[].label
Select nutrients in the ovine uterine lumen. VI. Expression of FK506-binding protein 12-rapamycin complex-associated protein 1 (FRAP1) and regulators and effectors of mTORC1 and mTORC2 complexes in ovine uteri and conceptuses.

# publications[].label
Aquaporins in the female reproductive system of mammals.

# researcherOn[].label
Incorporation of Endothelial Progenitor Cells Into Placental Vasculature

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Regulation of water and ion transport by arginine in porcine conceptuses

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# researcherOn[].label
Paracrine and Autocrine Signaling Between the Conceptus and Uterus in Pigs

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# researcherOn[].label
Roles of fructose and glucose in growth and development of ovine and porcine conceptuses

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# researcherOn[].label
Arginine and Secreted Phosphoprotein 1 Mediate Cell Signaling to Enhance Conceptus Development and Survival

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# streetAddress
Texas A&M University; Veterinary Integrative Biosciences; 4458 TAMU

# organizations[]
College of Veterinary Medicine and Biomedical Sciences

# organizations[]
School of Veterinary Medicine and Biomedical Sciences

# schools[]
College of Veterinary Medicine and Biomedical Sciences

# schools[]
School of Veterinary Medicine and Biomedical Sciences

# inTheNews[].label
Texas A&M University Announces 2020 EDGES Fellows

# inTheNews[].label
Texas A&M Announces 2020 Distinguished Achievement Award Recipients