# overview
My research focuses on proteomics, lipidomics, biophysical chemistry and application and development of mass spectrometry, such as "label-free" nano-particle based biosensors and novel peptide/protein isolation and purification strategies. We are also investigating the structure(s) of model peptides in an effort to better describe folding/unfolding and structure of membrane and intrinsically disordered (IDP) proteins. Peptides take on very different 2?, 3? and 4? structure, which determine or influence bio-activity. In the presence of lipid vesicles peptides can exist as solution-phase species, "absorbed" on lipid bilayers or "inserted" (as a monomer or multimer) in lipid bilayers. By what mechanism do peptides interact with lipid membranes to affect these structural changes, how do peptide-lipid interactions promote self-assembly to form intermediates that eventually yield aggregates, i.e., amyloid fibrils, or how does metal ion coordination affect the structure of metalloproteins? Mass spectrometry-based experiments, hydrogen/deuterium (H/D) exchange, chemical 'foot-printing' and gas-phase (ion-molecule and ion-ion reaction chemistry) and solution-phase chemical modifications, have expanded our abilities to address such questions, and new instrumental approaches, esp. ion mobility spectrometry (IMS) combined with enhanced molecular dynamics simulations (MDS), have become standard tools for structural-mass spectrometry studies. Over the past several years we have either acquired or developed novel, next-generation IM-MS instruments that are redefining cutting-edge structural-mass spectrometry research as well as cutting-edge computational tools essential to carry out these studies. Our new laboratories in the Interdisciplinary Life Sciences Building (ILSB) provides exciting opportunities for collaborative, interdisciplinary research with chemical-biologists, biochemists and other chemists.

# keywords[]
3205 Medical Biochemistry And Metabolomics

# keywords[]
Matrix Assisted Laser Desorption Ionization

# keywords[]
0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics

# keywords[]
3205 Medical Biochemistry And Metabolomics

# keywords[]
Oxidoreductases Acting On Sulfur Group Donors

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
3404 Medicinal And Biomolecular Chemistry

# keywords[]
3205 Medical Biochemistry And Metabolomics

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
3404 Medicinal And Biomolecular Chemistry

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
High-temperature Requirement A Serine Peptidase 2

# keywords[]
0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics

# keywords[]
0306 Physical Chemistry (incl. Structural)

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Periodic Focusing Drift Tube Ion Mobility

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
Peptide And Protein Complex Secondary Structure

# keywords[]
0306 Physical Chemistry (incl. Structural)

# keywords[]
0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics

# educationAndTraining[].organization.label
University of Nebraska–Lincoln - (Lincoln, United States)

# educationAndTraining[].organization.label
University of Arkansas at Little Rock - (Little Rock, Arkansas, United States)

# awardsAndHonors[].label
Frank H Field and Joe L Franklin Award for Outstanding Achievement in Mass Spectrometry

# publications[].label
Proteomic methods for biomarker discovery in a rat model of alcohol steatosis.

# publications[].label
Surface Activity of Amines Provides Evidence for the Combined ESI Mechanism of Charge Reduction for Protein Complexes.

# publications[].label
First-Principles Collision Cross Section Measurements of Large Proteins and Protein Complexes.

# publications[].label
A facile system for genetic incorporation of two different noncanonical amino acids into one protein in Escherichia coli.

# publications[].label
A high repetition rate (1 kHz) microcrystal laser for high throughput atmospheric pressure MALDI-quadrupole-time-of-flight mass spectrometry.

# publications[].label
Examining the effects of the sample water content on the MALDI mass spectra

# publications[].label
THE DESIGN AND PERFORMANCE EVALUATION OF A NEW HIGH-PERFORMANCE MASS-ANALYZED ION KINETIC-ENERGY (MIKE) SPECTROMETER

# publications[].label
Frataxin Traps Low Abundance Quaternary Structure to Stimulate Human Fe-S Cluster Biosynthesis

# publications[].label
Cryogenic ion mobility-mass spectrometry captures hydrated ions produced during electrospray ionization.

# publications[].label
Sub-femtomole peptide detection in ion mobility-time-of-flight mass spectrometry measurements.

# publications[].label
STUDY OF TARGET GAS EXCITATION ACCOMPANYING COLLISIONAL ACTIVATION OF LARGE POLYATOMIC IONS

# publications[].label
Investigation of the interaction of iron(III) complexes with dAMP by ESI-MS, MALDI-MS and potentiometric titration: insights into synthetic nuclease behavior.

# publications[].label
THE DEVELOPMENT OF FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE FOR HIGH MASS BIOMOLECULES

# publications[].label
Comparative peptidomics of four related hemipteran species: pyrokinins, myosuppressin, corazonin, adipokinetic hormone, sNPF, and periviscerokinins.

# publications[].label
DIFFERENTIATING GEOMETRIC ISOMERS BY LASER ION-BEAM PHOTODISSOCIATION

# publications[].label
Guest packing motifs within a supramolecular nanocapsule and a covalent analogue.

# publications[].label
Mechanistic Insights of IscU Conformation Regulation for FeS Cluster Biogenesis Revealed by Variable-Temperature Electrospray Ionization Native Ion Mobility Mass Spectrometry

# publications[].label
Biodegradation of triclosan by a wastewater microorganism

# publications[].label
Negative ion fragmentation of cysteic acid containing peptides: cysteic acid as a fixed negative charge.

# publications[].label
Ion mobility-mass spectrometry: a new paradigm for proteomics

# publications[].label
Efficient electrophoretic method to remove neutral additives from protein solutions followed by mass spectrometry analysis.

# publications[].label
Native ion mobility mass spectrometry of membrane protein complexes

# publications[].label
Temperature-Dependent Trimethylamine N-Oxide Induced the Formation of Substance P Dimers.

# publications[].label
LIGAND EFFECTS ON TRANSITION-METAL CLUSTER FORMATION - THE REACTIONS OF FEL+ WITH FE(CO)5

# publications[].label
Ion mobility-mass spectrometry: From proteomics to probing peptide/protein-ligand interactions.

# publications[].label
Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions.

# publications[].label
Ions from Solution to the Gas Phase: A Molecular Dynamics Simulation of the Structural Evolution of Substance P during Desolvation of Charged Nanodroplets Generated by Electrospray Ionization.

# publications[].label
Repurposing Halicin as a Potent Covalent Inhibitor for the SARS-CoV-2 Main Protease

# publications[].label
Silver nanoparticles as selective ionization probes for analysis of olefins by mass spectrometry.

# publications[].label
Identification of proteins from whole cell lysates: High resolution time-of-flight mass spectrometry

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
EVALUATION OF PULSED FAST-ATOM BOMBARDMENT IONIZATION FOR INCREASED SENSITIVITY OF TANDEM MASS-SPECTROMETRY

# publications[].label
Dissociative chemistry of ionic transition metal cluster fragments

# publications[].label
Subunit Interactions within the Carbon-Phosphorus Lyase Complex from Escherichia coli.

# publications[].label
Molecular dynamics and ion mobility spectrometry study of model -hairpin peptide, trpzip1.

# publications[].label
Ion mobility-mass spectrometer interface for collisional activation of mobility separated ions.

# publications[].label
Comparative studies of 193-nm photodissociation and TOF-TOFMS analysis of bradykinin analogues: the effects of charge site(s) and fragmentation timescales.

# publications[].label
Ions from solution to the gas phase: Effects of solvent on the final structure

# publications[].label
Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutants.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
CHEMICAL-PROPERTIES OF THE FULVENE RADICAL CATION - A CYCLOADDITION WITH 1,3-BUTADIENE

# publications[].label
Template effect for O-2 addition across cis-sulfur sites in nickel dithiolates

# publications[].label
UC/MALDI-MS analysis of HDL; evidence for density-dependent post-translational modifications.

# publications[].label
Rapid capillary mixing experiments for the analysis of hydrophobic membrane complexes directly from aqueous lipid bilayer solutions.

# publications[].label
GAS-PHASE ION MOLECULE CHARGE-EXCHANGE REACTIONS OF FE+ WITH FE(CO)5 - OBSERVATION OF HIGHER LYING METASTABLE ELECTRONIC STATES

# publications[].label
Ratiometric pulsed alkylation mass spectrometry as a probe of thiolate reactivity in different metalloderivatives of Staphylococcus aureus pI258 CadC.

# publications[].label
ENERGY PARTITIONING IN PHOTOFRAGMENT SPECTROSCOPY - CORRELATIONS WITH ENERGY-GAP

# publications[].label
Effects of endotoxin on gastric injury from luminal irritants in rats: potential roles of nitric oxide.

# publications[].label
Performance evaluation of in-source ion activation hardware for collision-induced unfolding of proteins and protein complexes on a drift tube ion mobility-mass spectrometer.

# publications[].label
A NEW GENERATION OF HIGH-PERFORMANCE MASS SPECTROMETERS FOR ENVIRONMENTAL CHEMISTRY - TANDEM MAGNETIC-SECTOR TIME-OF-FLIGHT AND FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE

# publications[].label
AXIAL MAGNETIC INHOMOGENEITIES AND LOW-ENERGY ION INJECTION IN FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE SPECTROMETRY

# publications[].label
Effects of matrix structure/acidity on ion formation in matrix-assisted laser desorption ionization mass spectrometry

# publications[].label
Studies on the biosynthesis of phomoidride B (CP-263,114): evidence for a decarboxylative homodimerization pathway.

# publications[].label
Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry.

# publications[].label
Separation of conventional and distonic radical cations of CH3-X using nitrogen-cooled ion mobility time-of-flight mass spectrometry.

# publications[].label
Structural basis for lipid and copper regulation of the ABC transporter MsbA.

# publications[].label
A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease.

# publications[].label
ION MOLECULE REACTION CHEMISTRY OF IONIC TRANSITION-METAL CARBONYL CLUSTER FRAGMENTS .1. LIGAND-EXCHANGE REACTIONS OF CR2(CO)Y(+) IONS

# publications[].label
Distinguishing between phosphorylated and nonphosphorylated peptides with ion mobility-mass spectrometry.

# publications[].label
ChemInform Abstract: FORMATION OF IONIC TRANSITIONMETAL CARBONYL CLUSTER FRAGMENTS BY IONMOLECULE REACTIONS. 1. THE CHROMIUM HEXACARBONYL AND IRON PENTACARBONYL SYSTEMS

# publications[].label
From solution to the gas phase: factors that influence kinetic trapping of substance P in the gas phase.

# publications[].label
Discovery of Potent Charge-Reducing Molecules for Native Ion Mobility Mass Spectrometry Studies.

# publications[].id
simultaneous acquisition of multiple correlated MS1 and MS2 spectra

# publications[].label
Binding of DNA purine sites to dirhodium compounds probed by mass spectrometry.

# publications[].label
NEUTRAL-ION CORRELATION-MEASUREMENTS - A NOVEL TANDEM MASS-SPECTROMETRY DATA ACQUISITION MODE FOR TANDEM MAGNETIC-SECTOR REFLECTRON TIME-OF-FLIGHT INSTRUMENTS

# publications[].label
Gas-phase ion dynamics in a periodic-focusing DC ion guide (Part II): Discrete transport modes

# publications[].label
Entropy in the Molecular Recognition of Membrane Protein-Lipid Interactions.

# publications[].label
Characterizing the Conformationome: Toward a Structural Understanding of the Proteome.

# publications[].label
Determination of the protein composition of the occlusion-derived virus of Autographa californica nucleopolyhedrovirus.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Proteomics and mass spectrometry: Reading protein expression by high resolution mass spectrometry of whole cell lysates.

# publications[].label
Protein characterization by high resolution mass spectrometry: The practical utility of accurate mass measurements.

# publications[].label
Unveiling the Hidden: Dissecting Liraglutide Oligomerization Dual Pathways via Direct Mass Technology, Electron-Capture Dissociation, and Molecular Dynamics

# publications[].label
Improving mass spectrometric sequencing of arginine-containing peptides by derivatization with acetylacetone.

# publications[].label
Studies of histidine as a suitable isoelectric buffer for tryptic digestion and isoelectric trapping fractionation followed by capillary electrophoresis-mass spectrometry for proteomic analysis.

# publications[].label
Identification of individual proteins in complex protein mixtures by high-resolution, high-mass-accuracy MALDI TOF-mass spectrometry analysis of in-solution thermal denaturation/enzymatic digestion.

# publications[].label
Test of the potential of a dATP surrogate for sequencing via MALDI-MS.

# publications[].label
Effect of cysteic acid position on the negative ion fragmentation of proteolytic derived peptides.

# publications[].label
SYNTHESIS AND FOLDING OF A MANDUCA-SEXTA ECLOSION HORMONE (EH) AND ITS ANALOGS

# publications[].label
On the structure elucidation using ion mobility spectrometry and molecular dynamics.

# publications[].label
Protons Are Fast and Smart; Proteins Are Slow and Dumb: On the Relationship of Electrospray Ionization Charge States and Conformations.

# publications[].label
High-resolution ion partitioning technique by phase-specific ion excitation for Fourier transform ion cyclotron resonance.

# publications[].label
Posttranslational modification of CENP-A influences the conformation of centromeric chromatin.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
DIVERGENT PATHWAYS FOR THE ADDITION OF DIOXYGEN TO SULFUR IN NICKEL CIS-DITHIOLATES - AN ISOTOPOMERIC ANALYSIS

# publications[].label
The contributions of molecular framework to IMS collision cross-sections of gas-phase peptide ions.

# publications[].label
ChemInform Abstract: LASER BEAMION BEAM PHOTODISSOCIATION STUDIES OF C6H6+ RADICAL CATIONS: THE 2,4HEXADIYNE SYSTEM

# publications[].label
A novel surface-induced dissociation instrument for ion mobility-time-of-flight mass spectrometry

# publications[].label
How alkali metal ion binding alters the conformation preferences of gramicidin A: a molecular dynamics and ion mobility study.

# publications[].label
Mineralization of acephate, a recalcitrant organophosphate insecticide is initiated by a pseudomonad in environmental samples.

# publications[].label
Ion Mobility-Mass Spectrometry: A Tool for Characterizing the Petroleome

# publications[].label
LIQUID SAMPLE INTRODUCTION FOR MATRIX ASSISTED LASER DESORPTION IONIZATION

# publications[].label
Multiplex data acquisition modes for ion mobility-mass spectrometry

# publications[].label
Factors that influence helical preferences for singly charged gas-phase peptide ions: the effects of multiple potential charge-carrying sites.

# publications[].label
Fast-atom bombardment tandem mass spectrometry studies of organo-alkali-metal ions of small peptides. Competitive interaction of sodium with basic amino acid substituents.

# publications[].label
Probing the electron capture dissociation mass spectrometry of phosphopeptides with traveling wave ion mobility spectrometry and molecular dynamics simulations.

# publications[].label
Melting Proteins: Evidence for Multiple Stable Structures upon Thermal Denaturation of Native Ubiquitin from Ion Mobility Spectrometry-Mass Spectrometry Measurements.

# publications[].label
The influence and utility of varying field strength for the separation of tryptic peptides by ion mobility-mass spectrometry.

# publications[].label
THE STRUCTURE OF DECOMPOSING [C7H7O]+ IONS - BENZYL VERSUS TROPYLIUM ION STRUCTURES

# publications[].label
NOVEL MASS-SPECTROMETER FOR ION KINETIC-ENERGY SPECTROSCOPY (IKES)

# publications[].label
Two capa-genes are expressed in the neuroendocrine system of Rhodnius prolixus.

# publications[].label
StructureReactivity Relationships for Ionic Transition Metal Carbonyl Cluster Fragments

# publications[].label
Focus on the 20-year anniversary of SEQUEST.

# publications[].label
Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass measurement accuracy by using delayed extraction.

# publications[].label
A collision cross-section database of singly-charged peptide ions (vol 18, pg 1232, 2007)

# publications[].label
A novel approach to collision-induced dissociation (CID) for ion mobility-mass spectrometry experiments.

# publications[].label
Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time

# publications[].label
Investigation of the dynamics of matrix-assisted laser desorption ionization ion formation using an electrostatic analyzer/time-of-flight mass spectrometer

# publications[].label
A universal strategy for proteomic studies of SUMO and other ubiquitin-like modifiers.

# publications[].label
Utility of CE-MS data in protein identification.

# publications[].label
Photochemistry and proton transfer reaction chemistry of selected cinnamic acid derivatives in hydrogen bonded environments

# publications[].label
KETO-ENOL TAUTOMERISM OF GAS-PHASE IONS - STRUCTURE OF REACTIVE C6H6O RADICAL CATIONS

# publications[].label
Effect of lysine methylation on charge state distribution and conformational preferences of peptides in the gas phase utilizing ion mobility - mass spectrometry

# publications[].label
Trafficking of ODV-E66 is mediated via a sorting motif and other viral proteins: facilitated trafficking to the inner nuclear membrane.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Laser desorption studies of high mass biomolecules in Fourier-transform ion cyclotron resonance mass spectrometry.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
LASER-ION BEAM PHOTODISSOCIATION STUDIES OF C4H4 RADICAL CATIONS

# publications[].label
FRAGMENTATION OF VITAMIN-B-12 DURING 337 NM MATRIX-ASSISTED LASER-DESORPTION IONIZATION

# publications[].label
Mass spectrometric assignment of Leu/Ile in neuropeptides from single neurohemal organ preparations of insects.

# publications[].label
Fine-tuning the ring-size of metallacyclophanes: a rational approach to molecular pentagons.

# publications[].label
Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease.

# publications[].label
Ion Mobility-Mass Spectrometry Reveals the Energetics of Intermediates that Guide Polyproline Folding.

# publications[].label
Some Aspects of the Chemistry of Ionic Organo-Alkali Metal Halide Clusters Formed by Desorption Ionization

# publications[].label
ELECTROCYCLIC RING-OPENING OF THE CYCLOBUTENE RADICAL CATION

# publications[].label
Dynamic maldi patterning and multidimensional separations for imaging MS: New avenues for the biomolecular microscope.

# publications[].label
Chemical residue evidence in Leon Plain pottery from the Toyah phase (1300-1650 CE) in the American Southern Plains

# publications[].label
Novel method for [M+Cu]+ ion formation by matrix-assisted laser desorption ionization

# publications[].label
Fourier transform ion mobility-orbitrap for native mass spectrometry

# publications[].label
Proteolysis in mixed organic-aqueous solvent systems: applications for peptide mass mapping using mass spectrometry.

# publications[].label
STRUCTURAL DETERMINATION OF [C7H7O]+ IONS IN THE GAS-PHASE BY ION-CYCLOTRON RESONANCE SPECTROMETRY

# publications[].label
PETR 156-Ion mobility-mass spectrometry (IM-MS) as a structural probe of gas-phase ions

# publications[].label
MECHANISM OF DIOXYGEN ADDITION TO NICKEL-BOUND THIOLATES

# publications[].label
CisTrans Isomerization of Pro(7) in Oxytocin Regulates Zn(2+) Binding.

# publications[].label
Matrix-assisted laser desorption ionization hydrogen/deuterium exchange studies to probe peptide conformational changes.

# publications[].label
Thermal Analysis of a Mixture of Ribosomal Proteins by vT-ESI-MS: Toward a Parallel Approach for Characterizing the Stabilitome.

# publications[].label
ChemInform Abstract: Formation of Ionic Transition Metal Carbonyl Cluster Fragments by IonMolecule Reactions.

# publications[].label
Identification of the first neuropeptides from the CNS of Hemiptera: CAPA peptides of the southern green stinkbug Nezara viridula (L.).

# publications[].label
Neuropeptidomics of the mosquito Aedes aegypti.

# publications[].label
Petroleum crude oil characterization by IMS-MS and FTICR MS.

# publications[].label
Double and triple thermodynamic mutant cycles reveal the basis for specific MsbA-lipid interactions.

# publications[].label
Ion mobility-mass spectrometry applied to cyclic peptide analysis: conformational preferences of gramicidin S and linear analogs in the gas phase.

# publications[].label
Polycarbonates derived from glucose via an organocatalytic approach.

# publications[].label
TRANSFORMATION OF POLYSULFIDIC SULFUR TO ELEMENTAL SULFUR IN A CHELATED IRON, HYDROGEN-SULFIDE OXIDATION PROCESS

# publications[].label
NEW CONCEPTS IN TANDEM MASS-SPECTROMETRY - TANDEM TIME-OF-FLIGHT MASS-SPECTROMETRY

# publications[].label
Instrument And Method For Energizing Molecules In Charged Droplets

# publications[].label
Collision-Induced Unfolding Studies of Proteins and Protein Complexes using Drift Tube Ion Mobility-Mass Spectrometer.

# publications[].label
Mass measurement accuracy of matrix-assisted laser desorbed biomolecules: a Fourier-transform ion cyclotron resonance mass spectrometry study.

# publications[].label
LASER-ION BEAM PHOTODISSOCIATION STUDIES OF C6H6+ RADICAL CATIONS - THE 2,4-HEXADIYNE SYSTEM

# publications[].label
Evaluation of the variables that affect resolution in delayed extraction MALDI-TOF

# publications[].label
In situ droplet-based on-tissue chemical derivatization for lipid isomer characterization using LESA.

# publications[].label
Experimental and theoretical studies of (CsI)n Cs+ cluster ions produced by 355 nm laser desorption ionization.

# publications[].label
Combining isoelectric point-based fractionation, liquid chromatography and mass spectrometry to improve peptide detection and protein identification.

# publications[].label
ION-MOLECULE REACTION CHEMISTRY OF VARIOUS GAS-PHASE C6H6 RADICAL CATIONS

# publications[].label
CHEMISTRY OF C6H6O RADICAL CATIONS - STUDY OF REARRANGEMENT REACTIONS OF HALOGEN SUBSTITUTED ETHYL PHENYL ETHERS

# publications[].label
Modified Ion Source for the Improved Collisional Activation of Protein Complexes.

# publications[].label
Temperature Regulates Stability, Ligand Binding (Mg2+ and ATP) and Stoichiometry of GroEL/GroES Complexes

# publications[].label
Hepatic phenotype of liver fatty acid binding protein gene-ablated mice.

# publications[].label
PHOTOCHEMISTRY AND PHOTOPHYSICS OF SMALL TRANSITION-METAL CLUSTER IONS

# publications[].label
Functional analysis of RNA binding by the hepatitis C virus RNA-dependent RNA polymerase.

# publications[].label
Biodegradation of triclosan by a wastewater microorganism.

# publications[].label
THE UTILITY OF A BIASED ACTIVATION CELL FOR LASER-ION BEAM PHOTODISSOCIATION STUDIES

# publications[].label
Analysis of phosphorylated peptides by ion mobility-mass spectrometry.

# publications[].label
Collision-Induced Unfolding of Partially Metalated Metallothionein-2A: Tracking Unfolding Reactions of Gas-Phase Ions.

# publications[].label
Topological Analysis of Transthyretin Disassembly Mechanism: Surface-Induced Dissociation Reveals Hidden Reaction Pathways.

# publications[].label
THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY-MASS SPECTROMETRY.

# publications[].label
Matrix-Assisted Laser Desorption Mass Spectrometry To Monitor Synthesis And Folding of Manduca Sexta Eclosion Hormone And Its Analogs

# publications[].label
RECENT PROGRESS IN THE DEVELOPMENT OF AN ANALYTICAL FT-ICR

# publications[].label
Atomic ions to intact protein complexes: 25-year quest for structure, dynamics, and thermodynamics

# publications[].label
Gas-phase ion dynamics in a periodic-focusing DC ion guide

# publications[].label
Molecular Mechanism of ISC Iron-Sulfur Cluster Biogenesis Revealed by High-Resolution Native Mass Spectrometry.

# publications[].label
Frataxin Traps Low Abundance Quaternary Structure to Stimulate Human Fe-S Cluster Biosynthesis.

# publications[].label
Melting proteins confined in nanodroplets with 10.6 m light provides clues about early steps of denaturation.

# publications[].label
Neuropeptides of the cotton fleahopper, Pseudatomoscelis seriatus (Reuter).

# publications[].label
Liver proteome analysis in a rodent model of alcoholic steatosis.

# publications[].label
Size-to-charge dispersion of collision-induced dissociation product ions for enhancement of structural information and product ion identification.

# publications[].label
Design and calibration of an electrostatic energy analyzer-time-of-flight mass spectrometer for measurement of laser-desorbed ion kinetic energies.

# publications[].label
Resolution equations for high-field ion mobility.

# publications[].label
A collision cross-section database of singly-charged peptide ions.

# publications[].label
Hydration of Guanidinium Ions: An Experimental Search for Like-Charged Ion Pairs.

# publications[].label
Aerosol matrix-assisted laser desorption ionization mass spectrometry.

# publications[].label
Proteome analysis of Escherichia coli K-12 by two-dimensional native-state chromatography and MALDI-MS.

# publications[].label
Evolution of Hydrogen-Bond Networks in Protonated Water Clusters H(+)(H2O)n (n = 1 to 120) Studied by Cryogenic Ion Mobility-Mass Spectrometry.

# publications[].label
Determining Membrane Protein-Lipid Binding Thermodynamics Using Native Mass Spectrometry.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
THE GAS-PHASE REACTION OF IONIC DINUCLEAR CLUSTER FRAGMENTS WITH HYDROGEN AND 1,3-BUTADIENE

# publications[].label
"Wet" Versus "Dry" Folding of Polyproline.

# publications[].label
Size-selected (2-10 nm) gold nanoparticles for matrix assisted laser desorption ionization of peptides.

# publications[].label
Capturing RAS oligomerization on a membrane.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Melting of Hemoglobin in Native Solutions as measured by IMS-MS.

# publications[].label
The waveguide below cutoff attenuation standard

# publications[].label
Anion Effects on Ionization Efficiency Using Gold Nanoparticles as Matrices for LDI-MS

# publications[].label
Expanding Native Mass Spectrometry to the Masses.

# publications[].label
ESI-IM-MS and Collision-Induced Unfolding That Provide Insight into the Linkage-Dependent Interfacial Interactions of Covalently Linked Diubiquitin.

# publications[].label
Synthesis, characterization and antibacterial activity of FeIII, CoII, CuII and ZnII complexes probed by transmission electron microscopy.

# publications[].label
Intrinsic GTPase Activity of K-RAS Monitored by Native Mass Spectrometry.

# publications[].label
HIGH-PRECISION ARBITRARY WAVE-FORM GENERATOR FOR ION SELECTION IN FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE

# publications[].label
Inhibition of Subunit Exchange and N-Finger Rearrangement in SARS-CoV-2 Main Protease by Peptidomimetic Inhibitors

# publications[].label
Selective binding of a toxin and phosphatidylinositides to a mammalian potassium channel.

# publications[].label
Following a Folding Transition with Capillary Electrophoresis and Ion Mobility Spectrometry.

# publications[].label
Secondary structure of gas-phase model alanine-containing peptide ions in a low dielectric environment

# publications[].label
Nonlinear frequency modulation for Fourier transform ion mobility mass spectrometry improves experimental efficiency

# publications[].label
Characterization of poly(amidoamine) dendrimers and their complexes with Cu2+ by matrix-assisted laser desorption ionization mass spectrometry

# publications[].label
SOME GENERAL-ASPECTS OF THE CHEMISTRY OF ORGANO-ALKALI METAL-IONS - AN OVERVIEW OF RECENT WORK

# publications[].label
Development of a Fourier-transform ion cyclotron resonance mass spectrometer-ion mobility spectrometer

# publications[].label
THE GAS-PHASE CHEMISTRY OF TRANSITION-METAL CLUSTERS

# publications[].label
Investigating supported lipid bilayer electrophoresis systems with imaging mass spectrometry

# publications[].label
ChemInform Abstract: Tandem TimeofFlight Mass Spectrometry. A Magnetic SectorReflectron TimeofFlight Mass Spectrometer

# publications[].label
ChemInform Abstract: Some General Aspects of the Chemistry of OrganoAlkali Metal Ions. An Overview of Recent Work

# publications[].label
Increasing Isolation Efficiency Using a Segmented Quadrupole Mass Filter Operated with Rectangular Waveforms.

# publications[].label
Developing IM-MS as a proteomics-mass spectral imaging tool.

# publications[].label
FORMATION OF IONIC TRANSITION-METAL CARBONYL CLUSTER FRAGMENTS BY ION MOLECULE REACTIONS .2. THE CO(CO)3(NO) AND NI(CO)4 SYSTEMS

# publications[].label
Sexually dimorphic metabolism of branched-chain lipids in C57BL/6J mice.

# publications[].label
Fourier transform ion mobility-Orbitrap spectrometer for native mass spectrometry

# publications[].label
High-throughput method for on-target performic acid oxidation of MALDI-deposited samples.

# publications[].label
A Study of Ion-Neutral Collision Cross Section Values for Low Charge States of Peptides, Proteins, and Peptide/Protein Complexes.

# publications[].label
Editorial: Focus on Ionization Technologies Used in MS: Fundamentals and Applications, Honoring Dr. Sarah Trimpin, Recipient of the 2019 ASMS Biemann Medal.

# publications[].label
Fundamental studies of matrix-assisted laser desorption ionization

# publications[].label
MALDI and FAB mass spectrometry of nucleoside triphosphates: A comparative study

# publications[].label
Spatially dynamic laser patterning using advanced optics for imaging matrix assisted laser desorption/ionization (MALDI) mass spectrometry

# publications[].label
Advanced optics for rapidly patterned laser profiles in analytical spectrometry

# publications[].label
Peak capacity of ion mobility mass spectrometry: separation of peptides in helium buffer gas.

# publications[].label
New insights into the metal-induced oxidative degradation pathways of transthyretin.

# publications[].label
Ion mobility-mass spectrometry (IM-MS) for top-down proteomics: increased dynamic range affords increased sequence coverage.

# publications[].label
Effects of heavy-atom substituents on matrices used for matrix-assisted laser desorption-Ionization mass spectrometry.

# publications[].label
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of paclitaxel and related taxanes.

# publications[].label
An electrostatic focusing ion guide for ion mobility-mass spectrometry

# publications[].label
Increasing Ubiquitin Ion Resistance to Unfolding in the Gas Phase Using Chloride Adduction: Preserving More "Native-Like" Conformations Despite Collisional Activation.

# publications[].label
Gas-phase conformations of proteolytically derived protein fragments: Influence of solvent on peptide conformation

# publications[].label
Tracking the Structural Evolution of 4-Aminobenzoic Acid in the Transition from Solution to the Gas Phase.

# publications[].label
ChemInform Abstract: IonMolecule Reaction Chemistry of Ionic TransitionMetal Carbonyl Cluster Fragments. Part 1. LigandExchange Reactions of Cr2(CO)+ y Ions.

# publications[].label
Number of solution states of bradykinin from ion mobility and mass spectrometry measurements.

# publications[].label
Effects of charge states, charge sites and side chain interactions on conformational preferences of a series of model peptide ions.

# publications[].label
The waveguide below-cutoff attenuation standard

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Identification of PVK/CAP2b neuropeptides from single neurohemal organs of the stable fly and horn fly via MALDI-TOF/TOF tandem mass spectrometry.

# publications[].label
Reaction of Human Cd7metallothionein and N-Ethylmaleimide: Kinetic and Structural Insights from Electrospray Ionization Mass Spectrometry.

# publications[].label
High-resolution mass spectrometry and accurate mass measurements with emphasis on the characterization of peptides and proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

# publications[].label
Long-Lived Intermediates in a Cooperative Two-State Folding Transition.

# publications[].label
Ion mobility-mass spectrometry as a structural probe of intrinsically disordered peptides/proteins (IDP)

# publications[].label
CESIUM DESORPTION IONIZATION STUDIES OF BETA-CYCLODEXTRIN BY FOURIER-TRANSFORM MASS-SPECTROMETRY

# publications[].label
Profile and flight time analysis of bovine insulin clusters as a probe of matrix-assisted laser desorption/ionization ion formation dynamics.

# publications[].label
Temperature Regulates Stability, Ligand Binding (Mg2+ and ATP) and Stoichiometry of GroEL/GroES Complexes

# publications[].label
RECENT DEVELOPMENTS IN FTMS OF LARGE (GREATER-THAN-M/Z 5,000) BIOMOLECULES

# publications[].label
Award Address (Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry sponsored by Waters Corporation). Cryogenic ion mobility-mass spectrometry: A route to studies of biomolecule hydrate ions

# publications[].label
Structure and Stabilities of Solution and Gas Phase Protein Complexes.

# publications[].label
ION-MOLECULE REACTION CHEMISTRY OF FE+ WITH NO - EXCITED-VERSUS GROUND-STATE REACTIONS

# publications[].label
AN EVALUATION OF THE ANALYTICAL UTILITY OF THE PHOTODISSOCIATION OF FAST ION-BEAMS

# publications[].label
Fast atom bombardment--tandem mass spectrometry studies of organo-alkali metal ions of small peptides.

# publications[].label
Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain.

# publications[].label
Optimization of sample preparation for peptide sequencing by MALDI-TOF photofragment mass spectrometry.

# publications[].label
Selective regulation of human TRAAK channels by biologically active phospholipids.

# publications[].label
ChemInform Abstract: Formation of Ionic TransitionMetal Carbonyl Cluster Fragments by IonMolecule Reactions. Part 3. The Heteronuclear Systems.

# publications[].label
Polyamine detergents tailored for native mass spectrometry studies of membrane proteins.

# publications[].label
STUDIES ON THE CHEMISTRY OF PHOSPHORIC-ACID AND PHOSPHATE ESTER IONIC CLUSTERS

# publications[].label
ION MOLECULE REACTION CHEMISTRY OF IONIC TRANSITION-METAL CARBONYL CLUSTER FRAGMENTS - LIGAND-EXCHANGE REACTIONS OF MX(CO)Y+ (M INCLUDES CR, FE, AND NI) IONS

# publications[].label
Development and Evaluation of a Reverse-Entry Ion Source Orbitrap Mass Spectrometer.

# publications[].label
Longitudinal surface plasmon resonance based gold nanorod biosensors for mass spectrometry.

# publications[].label
AEI 6-Fragmentation of Cu-adducted peptides by MALDI TOFMS using gold nanoparticle matrices

# publications[].label
Water Plays Key Roles in Stabilities of Wild Type and Mutant Transthyretin Complexes.

# publications[].label
MASS AND ENERGY SELECTIVE ION PARTITIONING IN A 2-SECTION FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE SPECTROMETER CELL

# publications[].label
ISOTOPIC LABELING INVESTIGATION OF THE OXYGENATION OF NICKEL-BOUND THIOLATES BY MOLECULAR-OXYGEN

# publications[].label
Interkingdom responses of flies to bacteria mediated by fly physiology and bacterial quorum sensing

# publications[].label
Investigation of the dynamics of matrixassisted laser desorption/ionization ion formation using an electrostatic analyzer/timeofflight mass spectrometer

# publications[].label
Unimolecular dissociation reactions of methyl benzoate radical cation.

# publications[].label
Aerosol matrix-assisted laser desorption ionization mass spectrometry .1. Effect of solvent on ion signal

# publications[].label
ChemInform Abstract: Study of Target Gas Excitation Accompanying Collisional Activation of Large Polyatomic Ions

# publications[].label
Products of oxidation of microcystin-LR by ferrate(VI) as a function of reactant molar ratios and pH

# publications[].label
MALDI-MS as a monitor of the purification and folding of synthetic eclosion hormone.

# publications[].label
Revealing Anisotropic Growth of Liraglutide Oligomers by Native Ion Mobility Mass Spectrometry and Molecular Dynamics Simulation

# publications[].label
Fragmentation chemistry of [M + Cu]+ peptide ions containing an N-terminal arginine.

# publications[].label
Stability of 20S Proteasome Configurations: Preopening the Axial Gate.

# publications[].label
Investigation of the mechanism of the SpnF-catalyzed [4+2]-cycloaddition reaction in the biosynthesis of spinosyn A.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Multiplex data acquisition modes for ion mobility-mass spectrometry

# publications[].label
Coupling high-pressure MALDI with ion mobility/orthogonal time-of-flight mass spectrometry.

# publications[].label
Structure and function of normal and transformed murine acyl-CoA binding proteins.

# publications[].label
Tailoring nanoparticle surface chemistry to enhance laser desorption ionization of peptides and proteins.

# publications[].label
Collisional relaxation of metastable electronic states of Fe(+).

# publications[].label
Temperature Regulates Stability, Ligand Binding (Mg2+ and ATP) and Stoichiometry of GroEL/GroES Complexes

# publications[].label
FIELD-CORRECTED ION CELL FOR ION-CYCLOTRON RESONANCE

# publications[].label
Identification of the naturally occurring flavin of nitroalkane oxidase from fusarium oxysporum as a 5-nitrobutyl-FAD and conversion of the enzyme to the active FAD-containing form.

# publications[].label
LASER ION-BEAM PHOTODISSOCIATION STUDIES OF IONIC CLUSTER FRAGMENTS OF TRANSITION-METAL CARBONYLS

# publications[].label
Mechanistic Insights of IscU Conformation Regulation for FeS Cluster Biogenesis Revealed by Variable-Temperature Electrospray Ionization Native Ion Mobility Mass Spectrometry

# publications[].label
THE EXPANDING ROLE OF TIME-OF-FLIGHT MASS SPECTROMETERS IN ANALYTICAL MASS-SPECTROMETRY

# publications[].label
Molecular weight distributions of asphaltenes and deasphaltened oils studied by laser desorption ionization and ion mobility mass spectrometry.

# publications[].label
Increased ion transmission in IMS: A high resolution, periodic-focusing DC ion guide ion mobility spectrometer

# publications[].label
Editorial: Focus on Protein Footprinting, Honoring Michael Gross, Recipient of the 2020 John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry.

# publications[].label
Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues.

# publications[].label
Collision-Induced Unfolding of Partially Metalated Metallothionein-2A: Tracking Unfolding Reactions of Gas-Phase Ions

# publications[].label
Pulsed-alkylation mass spectrometry for the study of protein folding and dynamics: development and application to the study of a folding/unfolding intermediate of bacterial luciferase.

# publications[].label
Ion detection by Fourier transform ion cyclotron resonance: the effect of initial radial velocity on the coherent ion packet.

# publications[].label
FORMATION OF IONIC TRANSITION-METAL CARBONYL CLUSTER FRAGMENTS BY ION MOLECULE REACTIONS .3. THE HETERONUCLEAR SYSTEMS

# publications[].label
Multi-anode detection in electrospray ionization time-of-flight mass spectrometry.

# publications[].label
AEROSOL MATRIX-ASSISTED LASER-DESORPTION IONIZATION - EFFECTS OF ANALYTE CONCENTRATION AND MATRIX-TO-ANALYTE RATIO

# publications[].label
Therapeutic modulation of anti-estrogen resistance through histone deacetylase inhibition.

# publications[].label
ION TRAPS AS DETECTORS FOR HIGH-SENSITIVITY MASS SPECTROMETERS - HYBRID TIME-OF-FLIGHT FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE (TOF/FT-ICR)

# publications[].label
Disintegrin, hemorrhagic, and proteolytic activities of Mohave rattlesnake, Crotalus scutulatus scutulatus venoms lacking Mojave toxin.

# publications[].label
Digital Quadrupole Isolation and Electron Capture Dissociation on an Extended Mass Range Q-TOF Provides Sequence and Structure Information on Proteins and Protein Complexes.

# publications[].label
Performance Evaluation of In-source Ion Activation Hardware for Collision-Induced Unfolding of Proteins and Protein Complexes on a Drift Tube Ion Mobility-Mass Spectrometer

# publications[].label
FORMATION OF IONIC TRANSITION-METAL CARBONYL CLUSTER FRAGMENTS BY ION MOLECULE REACTIONS .1. THE CR(CO)6 AND FE(CO)5 SYSTEMS

# publications[].label
Accurate mass measurement of DNA oligonucleotide ions using high-resolution time-of-flight mass spectrometry.

# publications[].label
Characterization of proteins utilized in the desulfurization of petroleum products by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

# publications[].label
Peak capacity of ion mobility mass spectrometry: the utility of varying drift gas polarizability for the separation of tryptic peptides.

# publications[].label
Measurement of positional isotope exchange rates in enzyme-catalyzed reactions by fast atom bombardment mass spectrometry: application to argininosuccinate synthetase.

# publications[].label
A facile method to synthesize histones with posttranslational modification mimics.

# publications[].label
Native-ESI and ion mobility-mass spectrometry: Expanding MS-based structural biology through understanding of chemical fundamentals

# publications[].label
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.

# publications[].label
ANYL 432-Applications of nanoparticles in laser desorption/ionization mass spectrometry

# publications[].label
Occurrence of insect kinins in the flesh fly, stable fly and horn fly-mass spectrometric identification from single nerves and diuretic activity.

# publications[].label
Substance P in Solution: Trans-to-Cis Configurational Changes of Penultimate Prolines Initiate Non-enzymatic Peptide Bond Cleavages.

# publications[].label
Elucidation of conformer preferences for a hydrophobic antimicrobial peptide by vesicle capture-freeze-drying: a preparatory method coupled to ion mobility-mass spectrometry.

# publications[].label
Surface-induced dissociation on a MALDI-ion mobility-orthogonal time-of-flight mass spectrometer: sequencing peptides from an "in-solution" protein digest.

# publications[].label
DYNAMICS OF MATRIX ASSISTED LASER DESORPTION IONIZATION MEASURED USING A HYBRID ELECTRIC SECTOR TIME-OF-FLIGHT MASS-SPECTROMETER

# publications[].label
PHOTODISSOCIATION STUDIES OF IONIC CLUSTER FRAGMENTS OF TRANSITION-METAL CARBONYLS

# publications[].label
Fluorescent probes for tracking the transfer of iron-sulfur cluster and other metal cofactors in biosynthetic reaction pathways.

# publications[].label
A fundamental introduction to ion mobility mass spectrometry applied to the analysis of biomolecules.

# publications[].label
Desorption ionization of cesium iodide by Fourier transform mass spectrometry.

# publications[].label
A convenient method for genetic incorporation of multiple noncanonical amino acids into one protein in Escherichia coli.

# publications[].label
Temperature Regulates Stability, Ligand Binding (Mg2+ and ATP) and Stoichiometry of GroEL/GroES Complexes

# publications[].label
Influence of water and enzyme SpnF on the dynamics and energetics of the ambimodal [6+4]/[4+2] cycloaddition.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Nanoparticles for Selective Laser Desorption/Ionization in Mass Spectrometry

# publications[].label
Structural Analysis of 14-3-3--Derived Phosphopeptides Using Electron Capture Dissociation Mass Spectrometry, Traveling Wave Ion Mobility Spectrometry, and Molecular Modeling.

# publications[].label
Focus on Ion Mobility Spectrometry, Honoring Gert von Helden, Martin F. Jarrold, and David E. Clemmer, Recipients of the 2018 John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry.

# publications[].label
Amino acid influence on copper binding to peptides: cysteine versus arginine.

# publications[].label
A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease

# publications[].label
Neuropeptides in Heteroptera: identification of allatotropin-related peptide and tachykinin-related peptides using MALDI-TOF mass spectrometry.

# publications[].label
Artifact-free matrix-assisted laser desorption ionization time-of-flight mass spectra of tert.-butyldimethylsilyl ether derivatives of cyclodextrins used for the synthesis of single-isomer, chiral resolving agents for capillary electrophoresis.

# publications[].label
Structure and function of the sterol carrier protein-2 N-terminal presequence (vol 47, pg 5915, 2008)

# publications[].label
Gas-phase purification of biomolecules by ion mobility for patterning microarrays and protein crystal growth

# publications[].label
VARIOUS ICR CELL GEOMETRIES IN MALDI FTICR EXPERIMENTS - THEORETICAL AND EXPERIMENTAL INVESTIGATIONS

# publications[].label
A dual time-of-flight apparatus for an ion mobility-surface-induced dissociation-mass spectrometer for high-throughput peptide sequencing

# publications[].label
Structural Analysis of the Effect of a Dual-FLAG Tag on Transthyretin.

# publications[].label
Isolation and characterization of two disintegrins inhibiting ADP-induced human platelet aggregation from the venom of Crotalus scutulatus scutulatus (Mohave Rattlesnake).

# publications[].label
Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.

# publications[].label
CHARACTERIZATION OF WATER-SOLUBLE ORGANICS IN HEAVY OIL RETORT BY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY SELECTIVE-ION CHROMATOGRAMS

# publications[].label
Native Mass Spectrometry of Membrane Protein-Lipid Interactions in Different Detergent Environments.

# publications[].label
Isolation and characterization of 26- and 30-kDa rat liver proteins immunoreactive to anti-sterol carrier protein-2 antibodies.

# publications[].label
BRD4354 Is a Potent Covalent Inhibitor against the SARS-CoV-2 Main Protease.

# publications[].label
Bortezomib Inhibits Open Configurations of the 20S Proteasome.

# publications[].label
Separation of spin-orbit coupled metastable states of Kr+ and Xe+ by ion mobility

# publications[].label
Effects of the water content in the sample preparation for MALDI on the mass spectra.

# publications[].label
Proteomic analysis of 3T3-L1 adipocyte mitochondria during differentiation and enlargement.

# publications[].label
Highresolution Mass Spectrometry and Accurate Mass Measurements with Emphasis on the Characterization of Peptides and Proteins by Matrixassisted Laser Desorption/Ionization Timeofflight Mass Spectrometry

# publications[].label
Ag+ Ion Binding to Human Metallothionein-2A Is Cooperative and Domain Specific.

# publications[].label
ChemInform Abstract: LaserIon Beam Photodissociation Studies of Ionic Cluster Fragments of TransitionMetal Carbonyls

# publications[].label
Thermal denaturation: a useful technique in peptide mass mapping.

# publications[].label
Photolytic mass laddering for fast characterization of oligomers on single resin beads

# publications[].label
Improvement of resolution, mass accuracy, and reproducibility in reflected mode DE-MALDI-TOF analysis of DNA using fast evaporation--overlayer sample preparations.

# publications[].label
Mechanistic consequences of chiral radical clock probes: analysis of the mononuclear non-heme iron enzyme HppE with 2-hydroxy-3-methylenecyclopropyl radical clock substrates.

# publications[].label
Unfolding of Hydrated Alkyl Diammonium Cations Revealed by Cryogenic Ion Mobility-Mass Spectrometry.

# publications[].label
Variable-Temperature ESI-IMS-MS Analysis of Myohemerythrin Reveals Ligand Losses, Unfolding, and a Non-Native Disulfide Bond.

# publications[].label
Observation of conserved solution-phase secondary structure in gas-phase tryptic peptides.

# publications[].label
Transformation products of oxidation of microcystin-LR by ferrate(V) and ferrate(IV): similarities and differences with ferrate(VI)

# publications[].label
ChemInform Abstract: IonMolecule Reactions of the Cr(CO) 5 Anion with Oxygen

# publications[].label
An experimental study of the solvent-dependent self-assembly/disassembly and conformer preferences of gramicidin A.

# publications[].label
ANYL 165-Selective nanomaterials for biological mass spectrometry

# publications[].label
Damping factor links periodic focusing and uniform field ion mobility for accurate determination of collision cross sections.

# publications[].label
Cultivation of lipid-producing bacteria with lignocellulosic biomass: effects of inhibitory compounds of lignocellulosic hydrolysates.

# publications[].label
Facile system for genetic incorporation of two different noncanonical amino acids into one protein in Escherichia coli

# publications[].label
Optimization of a Digital Mass Filter for the Isolation of Intact Protein Complexes in Stability Zone 1,1.

# publications[].label
Nanoelectrospray MS and MS-MS investigation of two polydendate Lewis acids, (C6F4Hg)3 and o-C6F4(HgCl)2, characterization and halide binding selectivity

# publications[].label
Direct analysis of protein mixtures using high resolution time-of-flight mass spectrometry.

# publications[].label
Fundamental Investigations of the Mechanism of Laser Desorption and Ionization in Matrix Assisted Laser Desorption / Ionization

# publications[].label
LASER-ION BEAM PHOTODISSOCIATION STUDIES OF C3H3BR+ AND C3H3CL+

# publications[].label
Histidine-modified polyproline-13 explores the nature of two-state cooperativity

# publications[].label
Recapitulating the frataxin activation mechanism in an engineered bacterial cysteine desulfurase supports the architectural switch model

# publications[].label
DECOMPOSITION OF THE 1,3-BUTADIENE RADICAL CATION ON THE MICROSECOND TO PICOSECOND TIME SCALE

# publications[].label
From solution to gas phase: the implications of intramolecular interactions on the evaporative dynamics of substance P during electrospray ionization.

# publications[].label
Genetic incorporation of an aliphatic keto-containing amino acid into proteins for their site-specific modifications.

# publications[].label
Characterization of Structural Changes of Metallothionein by Ion Mobility-Mass Spectrometry (IM-MS): Metal-Free Vs. Metallated Forms

# publications[].label
The Caulobacter crescentus phage phiCbK: genomics of a canonical phage.

# publications[].label
Differentiation of isotopically labeled nucleotides using fast atom bombardment tandem mass spectrometry.

# publications[].label
Conformation and Self-Assembly of the Transmembrane Peptide Gramicidin A: Insights from ion Mobility Spectrometry and Molecular Dynamics

# publications[].label
Implementing Digital-Waveform Technology for Extended m/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer.

# publications[].label
Ion motion in a Fourier transform ion cyclotron resonance wire ion guide cell

# publications[].label
Determination of copper binding sites in peptides containing basic residues: a combined experimental and theoretical study

# publications[].label
The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives.

# publications[].label
Metal-induced conformational changes of human metallothionein-2A: a combined theoretical and experimental study of metal-free and partially metalated intermediates.

# publications[].label
An ion mobility-mass spectrometry study of copper-metallothionein-2A: binding sites and stabilities of Cu-MT and mixed metal Cu-Ag and Cu-Cd complexes.

# publications[].label
LASER SPRAY IONIZATION FOR BIOLOGICAL MASS-SPECTROMETRY

# publications[].label
Identification of native flavin adducts from Fusarium oxysporum using accurate mass matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

# publications[].label
ELECTRONEGATIVITY AND THE REACTIONS OF XFE+ (X = CL, BR, I) WITH FE(CO)5

# publications[].label
Reproducibility and quantitation of matrix-assisted laser desorption ionization mass spectrometry: effects of nitrocellulose on peptide ion yields.

# publications[].label
Temperature Regulates Stability, Ligand Binding (Mg2+ and ATP), and Stoichiometry of GroEL-GroES Complexes.

# publications[].label
Imaging secondary metabolism of Streptomyces sp. Mg1 during cellular lysis and colony degradation of competing Bacillus subtilis.

# publications[].label
LIGAND EFFECTS ON THE CLUSTERING REACTIONS OF FEL+ WITH FE(CO)5

# publications[].label
A SPECIAL ISSUE DEDICATED TO THE OUTSTANDING SCIENTIFIC CAREER OF PROF. MICHAEL L. GROSS.

# publications[].label
Substance P in the Gas Phase: Conformational Changes and Dissociations Induced by Collisional Activation in a Drift Tube.

# publications[].label
Water-Mediated Dimerization of Ubiquitin Ions Captured by Cryogenic Ion Mobility-Mass Spectrometry.

# publications[].label
Characterization of the Metal-Binding Sites of Metallothioneins and Structural Changes Between Metal-Free and Metal-Bound Forms by Ion Mobility-Mass Spectrometry (IM-MS)

# publications[].label
A mass-selective variable-temperature drift tube ion mobility-mass spectrometer for temperature dependent ion mobility studies.

# publications[].label
Variation of CI-2 Conformers upon Addition of Methanol to Water: An IMS-MS-Based Thermodynamic Analysis.

# publications[].label
The structure of an insect chymotrypsin.

# publications[].label
Peptidomics of CNS-associated neurohemal systems of adult Drosophila melanogaster: a mass spectrometric survey of peptides from individual flies.

# publications[].label
Effect of uncoupling protein-1 expression on 3T3-L1 adipocyte gene expression.

# publications[].label
A new copper containing MALDI matrix that yields high abundances of [peptide + Cu]+ ions.

# publications[].label
The structure of gas-phase bradykinin fragment 1-5 (RPPGF) ions: an ion mobility spectrometry and H/D exchange ion-molecule reaction chemistry study.

# publications[].label
MATRIX-ASSISTED LASER-DESORPTION IONIZATION OF AEROSOLS - THE IONIZATION MECHANISM

# publications[].label
Structure and function of the sterol carrier protein-2 N-terminal presequence.

# publications[].label
Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis.

# publications[].label
Fast C18 solid-phase desalting/delipidation of the human serum apolipoproteins for matrix-assisted laser desorption ionization and electrospray ionization mass spectrometric analysis.

# publications[].label
Membrane charge and curvature determine interaction with acyl-CoA binding protein (ACBP) and fatty acyl-CoA targeting.

# publications[].label
Phase synchronization of an ion ensemble by frequency sweep excitation in Fourier transform ion cyclotron resonance.

# publications[].label
Cis-trans isomerizations of proline residues are key to bradykinin conformations.

# publications[].label
From solution to the gas phase: stepwise dehydration and kinetic trapping of substance P reveals the origin of peptide conformations.

# publications[].label
Conformationally Regulated Peptide Bond Cleavage in Bradykinin.

# publications[].label
COLLISIONAL ACTIVATION BY FOURIER-TRANSFORM MASS-SPECTROMETRY - A STUDY OF TARGET GAS EXCITATION

# publications[].label
Analysis of protein mixtures by matrix-assisted laser desorption ionization-ion mobility-orthogonal-time-of-flight mass spectrometry

# publications[].label
LIGAND FLUXIONALITY AND THE FORMATION OF CATIONIC IRON CARBONYL CLUSTERS

# publications[].label
Fourier Transform Mass Spectrometry for High Mass Applications

# publications[].label
Isolation and characterization of two distinct forms of liver fatty acid binding protein from the rat.

# publications[].label
Allostery Without Conformational Change: A Native Mass Spectrometry Perspective

# publications[].label
AN EVALUATION OF FOURIER-TRANSFORM MASS-SPECTROMETRY FOR HIGH MASS APPLICATIONS

# publications[].label
Mapping peptide/protein conformation space: A challenge for IM-MS

# publications[].label
Dissecting the Thermodynamics of ATP Binding to GroEL One Nucleotide at a Time.

# publications[].label
Detection of mass 16 241 ions by Fourier-transform mass spectrometry.

# publications[].label
Gas and Liquid Phase Diffusivities of Isomeric Metal Complexes Derived from Multifold Ring-Closing Metatheses: Ion Mobility Mass Spectrometry Trumps DOSY NMR

# publications[].label
A STUDY OF THE ION MOLECULE REACTIONS OF THE CR(CO)5-ANION WITH OXYGEN

# publications[].label
Solvent Mediation of Peptide Conformations: Polyproline Structures in Water, Methanol, Ethanol, and 1-Propanol as Determined by Ion Mobility Spectrometry-Mass Spectrometry.

# publications[].label
Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding.

# publications[].label
PHOTOFRAGMENT SPECTROSCOPY - CORRELATIONS BETWEEN ENERGY-GAP LAW AND ELECTRONIC-TO-TRANSLATIONAL ENERGY PARTITIONING

# publications[].label
ESI-IM-MS and Collision-Induced Unfolding That Provide Insight into the Linkage-Dependent Interfacial Interactions of Covalently Linked Diubiquitin

# publications[].label
ANYL 381-Fragmentation of Cu-adducted peptides by MALDI TOFMS using gold nanoparticle matrices

# publications[].label
Towards biophysical characterization of individual lipid binding events to membrane proteins

# publications[].label
A method for removal of N-BOC protecting groups from substrates on TFA-sensitive resins

# publications[].label
The molecular basis of sugar sensing in Drosophila larvae.

# publications[].label
Mass spectrometric analysis of putative capa-gene products in Musca domestica and Neobellieria bullata.

# publications[].label
Entropy in the molecular recognition of membrane protein-lipid interactions

# publications[].label
Conformations of protonated gas-phase bradykinin ions: evidence for intramolecular hydrogen bonding.

# publications[].label
CAPA-gene products in the haematophagous sandfly Phlebotomus papatasi (Scopoli)--vector for leishmaniasis disease.

# publications[].label
How Closely Related Are Conformations of Protein Ions Sampled by IM-MS to Native Solution Structures?

# publications[].label
Photodissociation of high molecular weight peptides and proteins in a two-stage linear time-of-flight mass spectrometer.

# publications[].label
SYNTHESIS OF IONIC MIXED TRANSITION-METAL CLUSTERS IN THE GAS-PHASE

# publications[].label
Desorption Ionization and Fourier Transform Mass Spectrometry for the Analysis of Large Biomolecules

# publications[].label
Detection of femtomole and sub-femtomole levels of peptides by tandem magnetic sector/reflectron time-of-flight mass spectrometry and matrix-assisted laser desorption ionization.

# publications[].label
The Influence of Lipid Bilayer Physicochemical Properties on Gramicidin A Conformer Preferences.

# publications[].label
Pro-sterol carrier protein-2: role of the N-terminal presequence in structure, function, and peroxisomal targeting.

# publications[].label
Mechanistic Insights into IscU Conformation Regulation for Fe-S Cluster Biogenesis Revealed by Variable Temperature Electrospray Ionization Native Ion Mobility Mass Spectrometry.

# publications[].label
Combining chemical labeling, bottom-up and top-down ion-mobility mass spectrometry to identify metal-binding sites of partially metalated metallothionein.

# publications[].label
Native IM-Orbitrap MS: Resolving What Was Hidden.

# publications[].label
Development of a Fourier-Transform Ion Cyclotron Resonance (FTICR) Mass Spectrometry Method for Studies of Metal Ion Excited States

# publications[].label
Peptide sequencing by MALDI 193-nm photodissociation TOF MS.

# publications[].label
Tandem quadrupole Fourier-transform mass spectrometry of oligopeptides and small proteins.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
DETERMINATION OF STRUCTURE OF GAS-PHASE IONIC SPECIES

# publications[].label
Sequence and side-chain specific photofragment (193 nm) ions from protonated substance P by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

# publications[].label
ARE PROTON-TRANSFER REACTIONS OF EXCITED-STATES INVOLVED IN UV LASER DESORPTION IONIZATION

# publications[].label
Mass spectrometry and structural biology: Ion mobility-mass spectrometry studies of water and water-mediated conformational preferences of peptides and proteins

# publications[].label
Periodic field focusing ion mobility spectrometer

# publications[].label
Structural basis for lipid and copper regulation of the ABC transporter MsbA

# publications[].label
The neuropeptidomics of Ixodes scapularis synganglion.

# publications[].label
Cryogenic Ion Mobility-Mass Spectrometry: Tracking Ion Structure from Solution to the Gas Phase.

# publications[].label
Characterization of lipid carbon-carbon double-bond isomerism via ion mobility-mass spectrometry (IMS-MS) combined with cuprous ion-induced fragmentation.

# publications[].label
A Cryogenic-Temperature Ion Mobility Mass Spectrometer for Improved Ion Mobility Resolution

# publications[].label
ION MOLECULE REACTION CHEMISTRY OF IONIC TRANSITION-METAL CARBONYL CLUSTER FRAGMENTS - LIGAND-EXCHANGE REACTIONS OF CRX(CO)Y+ IONS

# publications[].label
A mechanistic study of the H/D exchange reactions of protonated arginine and arginine-containing di- and tripeptides.

# publications[].label
LASER ION-BEAM PHOTODISSOCIATION STUDIES OF MODEL AMINO-ACIDS AND PEPTIDES

# publications[].label
Development of Native MS Capabilities on an Extended Mass Range Q-TOF MS.

# publications[].label
Detection of high-mass biomolecules in Fourier transform ion cyclotron resonance mass spectrometry: theoretical and experimental investigations.

# publications[].label
SYNTHESIS AND STRUCTURES OF DISTIBENE (RSB=SBR) AND BRIDGING STIBINIDENE (RSB) IRON COMPLEXES

# publications[].label
Optical spectroscopy and photometry of SAX J1808.4-3658 in outburst

# publications[].label
MALDI-TOF detection of spatial addressed phospholipid bilayers

# publications[].label
Evidence for Many Unique Solution Structures for Chymotrypsin Inhibitor 2: A Thermodynamic Perspective Derived from vT-ESI-IMS-MS Measurements.

# publications[].label
LASER ION-BEAM PHOTODISSOCIATION STUDIES OF IONIC CLUSTER FRAGMENTS OF IRON CARBONYLS - FE1-3 (CO)0-6+

# publications[].label
Ratiometric pulsed alkylation/mass spectrometry of the cysteine pairs in individual zinc fingers of MRE-binding transcription factor-1 (MTF-1) as a probe of zinc chelate stability.

# publications[].label
A PHOTODISSOCIATION STUDY OF 1,3-BUTADIENE

# publications[].label
A Focus Honoring Carol Robinson's Election to the National Academy of Sciences.

# publications[].label
Elucidation of chemical structures of pink-red pigments responsible for 'pinking' in macerated onion (Allium cepa L.) using HPLC-DAD and tandem mass spectrometry

# publications[].label
Alice in Switzerland or the fiduciary as common informer

# publications[].label
Anion template effect on the self-assembly and interconversion of metallacyclophanes.

# publications[].label
Characterizing intermediates along the transition from polyproline I to polyproline II using ion mobility spectrometry-mass spectrometry.

# publications[].label
Variable-temperature ion mobility time-of-flight mass spectrometry studies of electronic isomers of Kr2+ and CH3OH*+ radical cations.

# publications[].label
The periodic focusing ion funnel: theory, design, and experimental characterization by high-resolution ion mobility-mass spectrometry.

# publications[].label
Defining Noncovalent Ubiquitin Homodimer Interfacial Interactions through Comparisons with Covalently Linked Diubiquitin.

# researcherOn[].label
Developing Ion Mobility-Mass Spectrometry for Structural Characterization of Complex Molecular Systems

# researcherOn[].awardedBy.label
United States Department of Energy - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
A New Cryo-Ion Mobility Spectrometer for Studies of Biomolecule Hydration

# researcherOn[].awardedBy.label
National Science Foundation - (Arlington, Virginia, United States)

# researcherOn[].label
Innovative Native Ion Mobility Approaches for Transformational Measurements in Structural Biology

# researcherOn[].awardedBy.label
National Institute of General Medical Sciences - (Bethesda, Maryland, United States)

# streetAddress
Texas A&M University; Chemistry Department; 3255 TAMU

# etdChairOf[].label
Sawyer, Holly Ann (2004-12). Investigation of the effect of intra-molecular interactions on the gas-phase conformation of peptides as probed by ion mobility-mass spectrometry, gas-phase hydrogen/deuterium exchange, and molecular mechanics. Doctoral Dissertation.

# etdChairOf[].label
Chen, Shu-Hua (2015-04). Metalation and Demetalation of Human Metallothionein Studied by Ion Mobility Mass Spectrometry. Doctoral Dissertation.

# etdChairOf[].label
Tuvilla, Mavreen Rose (2013-05). Enzymatic Digestion in Aqueous-Organic Solvents: A Mass Spectrometry-Based Approach in Monitoring Protein Conformation Changes. Master's Thesis.

# etdChairOf[].label
Sun, Wenjian (2007-12). Development of a maldi − ion mobility−  surface-induced dissociation − time-of-flight mass spectrometer with novel collision source configurations for high throughput peptide sequencing. Doctoral Dissertation.

# etdChairOf[].label
Morgan, Joseph William (2005-12). Development of tandem time-of-flight instrumentation for the examination of prompt photodissociation of peptides using 193-nm radiation. Doctoral Dissertation.

# etdChairOf[].label
Lang, Phillip (2016-05). An Investigation of Polymer Encapsualted Gold Nanoparticles for Use in Analytical Methods for Proteomic Based Research. Master's Thesis.

# etdChairOf[].label
Sherrod, Stacy D. (2010-01). Development of Advanced Optics and High Resolution Instrumentation for Mass Spectrometry Based Proteomics. Doctoral Dissertation.

# etdChairOf[].label
Chen, Liuxi (2012-10). Gas-phase and Solution-phase Peptide Conformations Studied by Ion Mobility-mass Spectrometry and Molecular Dynamics Simulations. Doctoral Dissertation.

# etdChairOf[].label
Stumpo, Katherine Anne (2008-12). Size-selected 2, 5, and 10 nm gold nanoparticles for laser desorption/ionization mass spectrometry. Doctoral Dissertation.

# etdChairOf[].label
Kim, Doyong (2016-08). Monitorying the Desolvaiton of Ions and Create Candidate Structure for the Ions Detected by Ion Mobility-Mass Spectrometry Study by Molecular Dynamics Simulations. Doctoral Dissertation.

# etdChairOf[].label
Cologna, Stephanie Marie (2012-02). Isoelectric Trapping and Mass Spectrometry: Tools for Proteomics. Doctoral Dissertation.

# etdChairOf[].label
Kmiec, Kevin (2012-10). Factors Affecting the Fragmentation of Peptide Ions: Metal Cationization and Fragmentation Timescale. Doctoral Dissertation.

# etdChairOf[].label
Cong, Xiao (2015-04). Interactions of Cu2+ with Phosphatidylserine and Their Biological Implications. Doctoral Dissertation.

# etdChairOf[].label
McLean, Janel Renee (2007-08). Biophysical studies of anhydrous peptide structure. Doctoral Dissertation.

# etdChairOf[].label
Verbeck, Guido Fridolin (2006-05). Development of a variable-temperature ion mobility/ time-of-flight mass spectrometer for separation of electronic isomers. Doctoral Dissertation.

# etdChairOf[].label
Slaton, James Garrett (2007-05). Structure-property relationships in gas-phase protonated and metalated peptide ions. Doctoral Dissertation.

# etdChairOf[].label
Gamez, Roberto (2014-05). Development of and Application of Plasmonic Nanomaterials for Mass Spectrometry Based Biosensing. Doctoral Dissertation.

# etdChairOf[].label
Fort, Kyle Logan (2014-12). The Development and Utilization of the Periodic Focusing Ion Funnel. Doctoral Dissertation.

# etdChairOf[].label
Silveira, Joshua A (2013-11). Development of Ion Mobility-mass Spectrometry Instrumentation to Probe the Conformations and Capture the Solution to Gas Phase Transition of Electrosprayed Biomolecules. Doctoral Dissertation.

# etdChairOf[].label
Chen, Anqi (2016-08). Investigation of the Interaction Between Antimicrobial Peptides and Lipid Membranes Using Ion Mobility Mass Spectrometry Coupled with Isothermal Titration Calorimetry. Master's Thesis.