# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# overview
Fungal pathogens of cereal crops can cause devastating disruption to the global food supply, and the economic loss due to crop diseases can add up to billions of dollars annually worldwide. The Shim lab at Texas A&M University focused on studying fungal pathogens of field crops, particularly Fusarium species. Notably, hazardous Fusarium mycotoxins pose a significant threat to global food safety and human health. Crop losses as well as the regulatory, testing, and management costs associated with mycotoxins in the US tops $1 billion annually.

The Genus Fusarium has had a great negative impact on agriculture and food safety but also presents a great opportunity for answering many fundamental questions. We are pursuing new discoveries that will ultimately lead to innovative tools for controlling crop diseases and mycotoxin contamination. To broaden the impact, we are actively collaborating with colleagues at Texas A&M as well as other prominent institutions worldwide. We are also very excited about our collaborations with colleagues in Texas A&M Engineering to spearhead multidisciplinary projects that can innovate plant pathology research.

# hrJobTitle
Professor and Head of the Department of Plant Pathology and Microbiology

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
2.2 Factors Relating To The Physical Environment

# educationAndTraining[].organization.label
Purdue University - (West Lafayette, Indiana, United States)

# publications[].label
Genetic Variability and Geographical Distribution of Mycotoxigenic Fusarium verticillioides Strains Isolated from Maize Fields in Texas.

# publications[].label
Aflatoxins, fumonisins, and trichothecenes: a convergence of knowledge.

# publications[].label
Nitrogen repression of fumonisin B1 biosynthesis in Gibberella fujikuroi.

# publications[].label
The coiled-coil protein-binding motif in Fusarium verticillioides Fsr1 is essential for maize stalk rot virulence.

# publications[].label
Highly Potent Saccharification of Arthrospira maxima Glycogen by Fungal Amylolytic Enzyme from Trichoderma Species J113

# publications[].label
Protein kinase FgSch9 serves as a mediator of the target of rapamycin and high osmolarity glycerol pathways and regulates multiple stress responses and secondary metabolism in Fusarium graminearum.

# publications[].label
The putative monomeric G-protein GBP1 is negatively associated with fumonisin B production in Fusarium verticillioides.

# publications[].label
Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium.

# publications[].label
CZK3, a MAP kinase kinase kinase homolog in Cercospora zeae-maydis, regulates cercosporin biosynthesis, fungal development, and pathogenesis.

# publications[].label
A type 2C protein phosphatase FgPtc3 is involved in cell wall integrity, lipid metabolism, and virulence in Fusarium graminearum.

# publications[].label
FvBck1, a component of cell wall integrity MAP kinase pathway, is required for virulence and oxidative stress response in sugarcane Pokkah Boeng pathogen.

# publications[].label
Computational identification of genetic subnetwork modules associated with maize defense response to Fusarium verticillioides.

# publications[].label
Understanding fumonisin biosynthesis through functional genomics studies in Fusarium verticillioides

# publications[].label
Regulators of G-protein signalling in Fusarium verticillioides mediate differential host-pathogen responses on nonviable versus viable maize kernels.

# publications[].label
Molecular cloning, over-expression and enzymatic characterization of an endo-acting -1,3-glucanase from marine bacterium Mesoflavibacter zeaxanthinifaciens S86 in Escherichia coli

# publications[].label
The role of MADS-box transcription factors in secondary metabolism and sexual development in the maize pathogen Fusarium verticillioides.

# publications[].label
Regulation of fumonisin B(1) biosynthesis and conidiation in Fusarium verticillioides by a cyclin-like (C-type) gene, FCC1.

# publications[].label
GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.

# publications[].label
Aspergillus nidulans striatin (StrA) mediates sexual development and localizes to the endoplasmic reticulum.

# publications[].label
Identification and Characterization of Pathogenic and Endophytic Fungal Species Associated with Pokkah Boeng Disease of Sugarcane.

# publications[].label
Identification of genes associated with fumonisin biosynthesis in Fusarium verticillioides via proteomics and quantitative real-time PCR.

# publications[].label
Functional characterization of Rho family small GTPases in Fusarium graminearum.

# publications[].label
Enhanced Homologous Recombination in Fusarium verticillioides by Disruption of FvKU70, a Gene Required for a Non-homologous End Joining Mechanism

# publications[].label
FSR1 is essential for virulence and female fertility in Fusarium verticillioides and F. graminearum.

# publications[].label
Functional characterization of Fusarium verticillioides CPP1, a gene encoding a putative protein phosphatase 2A catalytic subunit.

# publications[].label
Development of a real-time microchip PCR system for portable plant disease diagnosis.

# publications[].label
Application of Game Theory to Explore the Dynamics of Host-Pathogen Association in Phytobiomes

# publications[].label
Isolation and characterization of Leptolyngbya sp. KIOST-1, a basophilic and euryhaline filamentous cyanobacterium from an open paddle-wheel raceway Arthrospira culture pond in Korea.

# publications[].label
Protein phosphatase 2A regulatory subunits perform distinct functional roles in the maize pathogen Fusarium verticillioides.

# publications[].label
Identification of genes expressed during cercosporin biosynthesisin Cercospora zeae-maydis

# publications[].label
Quantification of fungal colonization, sporogenesis, and production of mycotoxins using kernel bioassays.

# publications[].label
Fusarium verticillioides GBB1, a gene encoding heterotrimeric G protein beta subunit, is associated with fumonisin B biosynthesis and hyphal development but not with fungal virulence.

# publications[].label
Discrimination of droplets containing single cultured filamentous fungal cell using impedance spectroscopy

# publications[].label
Fusarium oxysporum f. sp. lycopersici C2H2 transcription factor FolCzf1 is required for conidiation, fusaric acid production, and early host infection.

# publications[].label
Sda1, a Cys2-His2 zinc finger transcription factor, is involved in polyol metabolism and fumonisin B1 production in Fusarium verticillioides.

# publications[].label
Computational Prediction of Pathogenic Network Modules in Fusarium verticillioides.

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
The Colletotrichum graminicola striatin orthologue Str1 is necessary for anastomosis and is a virulence factor.

# publications[].label
Fsr1, a striatin homologue, forms an endomembrane-associated complex that regulates virulence in the maize pathogen Fusarium verticillioides.

# publications[].label
Fusarium verticillioides GAP1, a gene encoding a putative glycolipid-anchored surface protein, participates in conidiation and cell wall structure but not virulence.

# publications[].label
A Rab GTPase protein FvSec4 is necessary for fumonisin B1 biosynthesis and virulence in Fusarium verticillioides.

# publications[].label
Gibberella zeae chitin synthase genes, GzCHS5 and GzCHS7, are required for hyphal growth, perithecia formation, and pathogenicity.

# publications[].label
Regulation of Fumonisin Biosynthesis in Fusarium verticillioides-Maize System

# publications[].label
A small molecule species specifically inhibits Fusarium myosin I.

# publications[].label
Involvement of a putative response regulator FgRrg-1 in osmotic stress response, fungicide resistance and virulence in Fusarium graminearum.

# publications[].label
Functional characterization of acetylglutamate synthase and phosphoribosylamine-glycine ligase genes in Gibberella zeae.

# publications[].label
A large-scale on-chip droplet incubation chamber enables equal microbial culture time

# publications[].label
The N-terminus region of the putative C2H2 transcription factor Ada1 harbors a species-specific activation motif that regulates asexual reproduction in Fusarium verticillioides.

# publications[].label
The transcription factor FgMed1 is involved in early conidiogenesis and DON biosynthesis in the plant pathogenic fungus Fusarium graminearum

# publications[].label
Functional analyses of heterotrimeric G protein G alpha and G beta subunits in Gibberella zeae.

# publications[].label
Transcriptome analysis of maize pathogen Fusarium verticillioides revealed FvLcp1, a secreted protein with type-D fungal LysM and chitin-binding domains, that plays important roles in pathogenesis and mycotoxin production.

# publications[].publisher
Korean Society for Microbiology and Biotechnology

# publications[].label
Morphological, Molecular, and Biochemical Characterization of Monounsaturated Fatty Acids-Rich Chlamydomonas sp. KIOST-1 Isolated from Korea.

# publications[].publisher
Korean Society for Microbiology and Biotechnology

# publications[].tags
12 Responsible Consumption and Production

# publications[].label
A conserved homeobox transcription factor Htf1 is required for phialide development and conidiogenesis in Fusarium species.

# publications[].label
Retrograde trafficking from the endosome to the trans-Golgi network mediated by the retromer is required for fungal development and pathogenicity in Fusarium graminearum.

# publications[].label
Characterizing co-expression networks underpinning maize stalk rot virulence in Fusarium verticillioides through computational subnetwork module analyses

# publications[].label
Quantification of fungal colonization, sporogenesis, and production of mycotoxins using kernel bioassays.

# publications[].label
The MAPKK FgMkk1 of Fusarium graminearum regulates vegetative differentiation, multiple stress response, and virulence via the cell wall integrity and high-osmolarity glycerol signaling pathways.

# publications[].label
Comparison of fumonisin B1 biosynthesis in maize germ and degermed kernels by Fusarium verticillioides.

# publications[].label
Malazy, a degenerate, species-specific transposable element in Cercospora zeae-maydis.

# publications[].label
Disruption of a maize 9-lipoxygenase results in increased resistance to fungal pathogens and reduced levels of contamination with mycotoxin fumonisin.

# publications[].label
Effective microwell plate-based screening method for microbes producing cellulase and xylanase and its application.

# publications[].publisher
Korean Society for Microbiology and Biotechnology

# publications[].label
The TOR signaling pathway regulates vegetative development and virulence in Fusarium graminearum.

# researcherOn[].label
Computational and functional characterization of Fusarium verticillioides transcription factors

# researcherOn[].awardedBy.label
National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
IDBR: TYPE A - Microfluidic Fungal Transformation System for Ultra High-Throughput Functional Genomics

# researcherOn[].awardedBy.label
National Science Foundation - (Arlington, Virginia, United States)

# streetAddress
Texas A&M University; Plant Pathology & Microbiology; 2132 TAMU

# organizations[]
College of Agriculture and Life Sciences

# schools[]
College of Agriculture and Life Sciences

# etdChairOf[].label
Kim, Mansuck (2016-02). Computational Identification of Functional Modules and Hub Genes Involved in Pathogenicity-Associated or Defense Response on Fusarium Verticillioides-Maize Interactions. Doctoral Dissertation.

# etdChairOf[].label
Sagaram, Uma Shankar (2009-05). Molecular characterization of genes regulating fumonisin biosynthesis and development in maize pathogen fusarium verticilliodes. Doctoral Dissertation.

# etdChairOf[].label
Ortiz, Carlos S (2013-04). Molecular Characterization of MADS-BOX Transcription Factors and Analysis of Field Population Diversity in the Maize Pathogen Fusarium verticillioides. Doctoral Dissertation.

# etdChairOf[].label
Shin, Joonhee (2012-07). Characterization of PP2A regulatory B subunits in Fusarium verticillioides. Master's Thesis.

# etdChairOf[].label
Choi, Yoon E (2009-05). Characterizing the regulatory mechanisms in fusarium verticillioides secondary metabolism using functional genomics approaches. Doctoral Dissertation.

# etdChairOf[].label
Malapi-Wight, Martha Maria (2013-04). The Role of Cys2-His2 Zinc Finger Transcription Factors in Polyol Metabolism, Asexual Development and Fumonisin Biosynthesis in Fusarium verticillioides. Doctoral Dissertation.