# overview
The main research focus of my lab is to understand how environmental (temperature, hypoxia, salinity) and anthropogenic (pharmaceuticals, contaminants) stressors affect animal physiology.  In particular, we are interested in understanding cardiovascular, respiratory, reproductive and metabolic responses to stressors.  We study effects of short (few hours/days) and long-term (weeks) stressors (individual or multiple) at all levels of biological organization (molecular, cellular, organ and whole-organism), and developmental stages (early life stage to adult).  Understanding how perturbations in the animal's environment mechanistically affect survival is important in assisting conservation efforts.  We are currently studying physiological responses in American alligators and local Gulf of Mexico fish species.

# keywords[]
Hypoxia-Inducible Factor 1, Alpha Subunit

# keywords[]
Follicle Stimulating Hormone, Beta Subunit

# educationAndTraining[].organization.label
Memorial University of Newfoundland - (St. John's, Newfoundland and Labrador, Canada)

# educationAndTraining[].organization.label
University of Southern Denmark - (Odense, Syddanmark, Denmark)

# educationAndTraining[].organization.label
University of Southern Denmark - (Odense, Syddanmark, Denmark)

# publications[].label
An integrated in vivo and in silico analysis of the metabolism disrupting effects of CPI-613 on embryo-larval zebrafish (Danio rerio).

# publications[].label
Long-term hypoxia exposure alters the cardiorespiratory physiology of steelhead trout (Oncorhynchus mykiss), but does not affect their upper thermal tolerance.

# publications[].label
Differential gene expression indicates modulated responses to chronic and intermittent hypoxia in corallivorous fireworms (Hermodice carunculata).

# publications[].label
Temperature and species-specific effects on 3-adrenergic receptor cardiac regulation in two freshwater teleosts: Channel catfish (Ictalurus punctatus) and common carp (Cyprinus carpio).

# publications[].label
The pharmaceutical prednisone affects sheepshead minnow (Cyprinodon variegatus) metabolism and swimming performance.

# publications[].label
Rapid plastic responses to chronic hypoxia in the bearded fireworm,Hermodice carunculata(Annelida: Amphinomidae)

# publications[].label
Quantification of 2-hydrazinopyridine derivatized steroid hormones in fathead minnow (Pimephales promelas) blood plasma using LC-ESI+/MS/MS.

# publications[].label
Constraints-based stoichiometric analysis of hypoxic stress on steroidogenesis in fathead minnows, Pimephales promelas.

# publications[].label
In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline.

# publications[].label
Involvement of (3)-adrenergic receptors in in vivo cardiovascular regulation in rainbow trout (Oncorhynchus mykiss).

# publications[].label
Correlations between environmental salinity levels, blood biochemistry parameters, and steroid hormones in wild juvenile American alligators (Alligator mississippiensis).

# publications[].label
Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis.

# publications[].label
In Silico analysis of perturbed steroidogenesis and gonad growth in fathead minnows (P. promelas) exposed to 17-ethynylestradiol.

# publications[].label
Short-term exposure to 12 brackish water has significant effects on the endocrine physiology of juvenile American alligator (Alligator mississippiensis).

# publications[].label
Oxygen consumption during and post-hypoxia exposure in bearded fireworms (Annelida: Amphinomidae).

# publications[].label
Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats.

# publications[].label
The interactive effects of a gradual temperature decrease and long-term food deprivation on cardiac and hepatic blood flows in rainbow trout (Oncorhynchus mykiss).

# publications[].label
Deimination Protein Profiles in Alligator mississippiensis Reveal Plasma and Extracellular Vesicle-Specific Signatures Relating to Immunity, Metabolic Function, and Gene Regulation.

# publications[].label
Effect of coronary perfusion on the basal performance, volume loading and oxygen consumption in the isolated resistance-headed heart of the trout Oncorhynchus mykiss.

# publications[].label
Expression levels of genes associated with oxygen utilization, glucose transport and glucose phosphorylation in hypoxia exposed Atlantic cod (Gadus morhua).

# publications[].label
Cardiorespiratory modifications, and limitations, in post-smolt growth hormone transgenic Atlantic salmon Salmo salar.

# publications[].label
Cardiovascular and haematological responses of Atlantic cod (Gadus morhua) to acute temperature increase.

# publications[].label
Physiological effects of salinity stress in wild American alligators (Alligator mississippiensis)

# publications[].label
In situ cardiac function in Atlantic cod (Gadus morhua): effects of acute and chronic hypoxia.

# publications[].label
Effects of chronic exposure to 12 saltwater on the endocrine physiology of juvenile American alligator (Alligator mississippiensis).

# publications[].label
Cod (Gadus morhua) cardiorespiratory physiology and hypoxia tolerance following acclimation to low-oxygen conditions.

# publications[].label
Effect of acute and chronic hypoxia on the swimming performance, metabolic capacity and cardiac function of Atlantic cod (Gadus morhua).