# positions[].label
Assistant Dean for Research and Professor

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Phex Phosphate Regulating Neutral Endopeptidase

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Receptor, Fibroblast Growth Factor, Type 2

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Phex Phosphate Regulating Neutral Endopeptidase

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Receptor, Fibroblast Growth Factor, Type 3

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Phex Phosphate Regulating Neutral Endopeptidase

# keywords[]
Receptors, Tumor Necrosis Factor, Type Ii

# keywords[]
Receptors, Tumor Necrosis Factor, Type I

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Phex Phosphate Regulating Neutral Endopeptidase

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Calcium And Phosphate Metabolic Disorders

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Calcium And Phosphate Metabolic Disorders

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Phex Phosphate Regulating Neutral Endopeptidase

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Vascular Endothelial Growth Factor Receptor-3

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Cyclic AMP Response Element-Binding Protein

# keywords[]
Receptor Activator Of Nuclear Factor-kappa B

# keywords[]
Receptor, Fibroblast Growth Factor, Type 3

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# keywords[]
Phex Phosphate Regulating Neutral Endopeptidase

# keywords[]
Bone Morphogenetic Protein Receptors, Type I

# educationAndTraining[].organization.label
University of Connecticut - (Storrs, Connecticut, United States)

# educationAndTraining[].organization.label
The University of Texas Health Science Center at San Antonio - (San Antonio, Texas, United States)

# educationAndTraining[].organization.label
University of Michigan-Ann Arbor - (Ann Arbor, Michigan, United States)

# publications[].label
Mutant DLX 3 disrupts odontoblast polarization and dentin formation.

# publications[].label
Phenotypic characterization of osteoarthritic osteocytes from the sclerotic zones: a possible pathological role in subchondral bone sclerosis.

# publications[].label
Key role for the transcriptional factor, osterix, in spine development.

# publications[].label
Blocking of proteolytic processing and deletion of glycosaminoglycan side chain of mouse DMP1 by substituting critical amino acid residues.

# publications[].label
Inactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects.

# publications[].label
Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development.

# publications[].label
Failure to process dentin matrix protein 1 (DMP1) into fragments leads to its loss of function in osteogenesis.

# publications[].label
FAM20C plays an essential role in the formation of murine teeth.

# publications[].label
Targeted disruption of BMP signaling through type IA receptor (BMPR1A) in osteocyte suppresses SOST and RANKL, leading to dramatic increase in bone mass, bone mineral density and mechanical strength.

# publications[].label
Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam).

# publications[].label
DMP1 overexpression prevents bone alterations, FGF23 elevations and cardiac hypertrophy in mice with chronic kidney disease

# publications[].label
Deer antler tissue contains two types of bone morphogenetic protein 4 mRNA transcripts.

# publications[].label
Loss of dentin sialophosphoprotein leads to periodontal diseases in mice.

# publications[].label
A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots.

# publications[].label
Myelopoiesis is regulated by osteocytes through Gs-dependent signaling.

# publications[].label
Bmpr1a Signaling in Cartilage Development and Endochondral Bone Formation.

# publications[].label
From Osteon Formation/Remodeling of Dog Bones to Loss of Cortical Bone in Human Bones

# publications[].label
The Ultrastructural Relationship Between Osteocytes and Dental Implants Following Osseointegration.

# publications[].label
Sclerostin antibody preserves the morphology and structure of osteocytes and blocks the severe skeletal deterioration after motor-complete spinal cord injury in rats.

# publications[].label
A Mutation in the Dmp1 Gene Alters Phosphate Responsiveness in Mice.

# publications[].label
Dentin phosphoprotein and dentin sialoprotein are cleavage products expressed from a single transcript coded by a gene on human chromosome 4. Dentin phosphoprotein DNA sequence determination.

# publications[].label
Application of Cell Lineage Tracing Combined with Immunofluorescence in the Study of Dentinogenesis.

# publications[].label
The importance of a potential phosphorylation site in enamelin on enamel formation.

# publications[].label
A novel role of periostin in postnatal tooth formation and mineralization.

# publications[].label
Identification of the haematopoietic stem cell niche and control of the niche size.

# publications[].label
Elevation of a full-thickness mucoperiosteal flap alone accelerates orthodontic tooth movement.

# publications[].label
Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell.

# publications[].label
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

# publications[].label
Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.

# publications[].label
From Osteon Formation/Remodeling of Dog Bones to Loss of Cortical Bone in Human Bones

# publications[].label
Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.

# publications[].label
Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice.

# publications[].label
Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects.

# publications[].label
Wnt3 and transforming growth factor- induce myofibroblast differentiation from periodontal ligament cells via different pathways.

# publications[].label
Tissue clearing of both hard and soft tissue organs with the PEGASOS method

# publications[].label
Expression analysis of -smooth muscle actin and tenascin-C in the periodontal ligament under orthodontic loading or in vitro culture.

# publications[].label
Reduced DMP1 expression precedes bone loss and FGF23 elevation in CKD

# publications[].label
Chondrogenesis and osteogenesis are one continuous developmental and lineage defined biological process.

# publications[].label
Alveolar Bone Marrow Gli1+ Stem Cells Support Implant Osseointegration.

# publications[].label
Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoter.

# publications[].label
Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling.

# publications[].label
Diabetes Activates Periodontal Ligament Fibroblasts via NF-B In Vivo.

# publications[].label
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures.

# publications[].label
The identification of critical time windows of postnatal root elongation in response to Wnt/-catenin signaling.

# publications[].label
Co-localization of Cell Lineage Markers and the Tomato Signal.

# publications[].label
Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis.

# publications[].label
Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells.

# publications[].label
GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation.

# publications[].label
Renal responses to parathyroid hormone in young chickens.

# publications[].label
Extracellular matrix protein 1, a direct targeting molecule of parathyroid hormone-related peptide, negatively regulates chondrogenesis and endochondral ossification via associating with progranulin growth factor.

# publications[].label
The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment.

# publications[].label
The Dentin matrix protein 1 (Dmp1) is specifically expressed in mineralized, but not soft, tissues during development.

# publications[].label
Expression of FAM20C in the osteogenesis and odontogenesis of mouse.

# publications[].label
Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation.

# publications[].label
Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene.

# publications[].label
Protective roles of DMP1 in high phosphate homeostasis.

# publications[].label
FGF/FGFR signaling in health and disease.

# publications[].label
Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype.

# publications[].label
Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts.

# publications[].label
Deletion of ferroportin in murine myeloid cells increases iron accumulation and stimulates osteoclastogenesis in vitro and in vivo

# publications[].label
FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling.

# publications[].label
The in vivo role of DMP-1 and serum phosphate on bone mineral composition.

# publications[].label
GEP, a local growth factor, is critical for odontogenesis and amelogenesis.

# publications[].label
Glycosaminoglycan chain of dentin sialoprotein proteoglycan.

# publications[].label
Effects of transverse bodily movements of maxillary premolars on the surrounding hard tissue.

# publications[].label
Transient Activation of the Hedgehog-Gli Pathway Rescues Radiotherapy-Induced Dry Mouth via Recovering Salivary Gland Resident Macrophages.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
An appropriate Wnt/-catenin expression level during the remodeling phase is required for improved bone fracture healing in mice.

# publications[].label
The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis.

# publications[].label
Expression of the invertebrate sea urchin P16 protein into mammalian MC3T3 osteoblasts transforms and reprograms them into "osteocyte-like" cells.

# publications[].label
DMP1 C-terminal mutant mice recapture the human ARHR tooth phenotype.

# publications[].label
Critical role of Bmpr1a in mandibular condyle growth.

# publications[].label
Letter to the Editor, "Osterix Regulates Tooth Root Formation in a Site-specific Manner".

# publications[].label
Effects of constitutive -catenin activation on vertebral bone growth and remodeling at different postnatal stages in mice.

# publications[].label
DMP1 and MEPE expression are elevated in osteocytes after mechanical loading in vivo: theoretical role in controlling mineral quality in the perilacunar matrix.

# publications[].label
Osteocyte-specific deletion of FGF23 partially corrects bone growth and mineralization in DMP1KO ARHR mice

# publications[].label
Osteocytes but not osteoblasts directly build mineralized bone structures.

# publications[].label
Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages.

# publications[].label
The plastic nature of the human bone-periodontal ligament-tooth fibrous joint.

# publications[].label
Roles of Chondrocytes in Endochondral Bone Formation and Fracture Repair.

# publications[].label
Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gs alpha Signaling

# publications[].label
DMP1 processing is essential to dentin and jaw formation.

# publications[].label
Elucidation of the sequence and the genomic organization of the human dentin matrix acidic phosphoprotein 1 (DMP1) gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II.

# publications[].label
In vivo Knockdown of GEP, a Novel Growth Factor in Cartilage, Led to Defects in Cartilage and Osteoarthritis

# publications[].label
Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes.

# publications[].label
Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis.

# publications[].label
Biomimetic engineering of nanofibrous gelatin scaffolds with noncollagenous proteins for enhanced bone regeneration.

# publications[].label
Partial Blocking of Mouse DSPP Processing by Substitution of Gly451–Asp452 Bond Suggests the Presence of Secondary Cleavage Site(s)

# publications[].label
Gli1+ Periodontium Stem Cells Are Regulated by Osteocytes and Occlusal Force.

# publications[].label
Post-natal effect of overexpressed DKK1 on mandibular molar formation.

# publications[].label
Genetic evidence for the vital function of Osterix in cementogenesis.

# publications[].label
Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits.

# publications[].label
Osteocytic Kindlin-2 regulates bone mass accrual and maintenance and mediates skeletal response to mechanical loading and PTH anabolism

# publications[].label
Resveratrol represses tumor necrosis factor /c-Jun N-terminal kinase signaling via autophagy in human dental pulp stem cells.

# publications[].label
Constitutive -catenin activation in osteoblasts impairs terminal osteoblast differentiation and bone quality.

# publications[].label
Beta-galactosidase staining in the skeleton.

# publications[].label
Effects of nanomechanical bone tissue properties on bone tissue strain: implications for osteocyte mechanotransduction.

# publications[].label
Erratum: HexaDarginine treatment increases 7B2PC2 activity in hypmouse osteoblasts and rescues the HYP phenotype

# publications[].label
Sequence and expression of bone morphogenetic protein 3 mRNA in prolonged cultures of fetal rat calvarial osteoblasts and in rat prostate adenocarcinoma PA III cells.

# publications[].label
Gain-of-function mutation of FGFR3 results in impaired fracture healing due to inhibition of chondrocyte differentiation.

# publications[].label
Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury.

# publications[].label
Aberrant miR-145-5p/-catenin signal impairs osteocyte function in adolescent idiopathic scoliosis.

# publications[].label
Critical roles of periostin in the process of orthodontic tooth movement.

# publications[].label
Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia.

# publications[].label
The vital role of Gli1+ mesenchymal stem cells in tissue development and homeostasis.

# publications[].label
Bone morphogenetic protein-2 gene controls tooth root development in coordination with formation of the periodontium.

# publications[].label
miRNA-101 acts as a tumor suppressor in oral squamous cell carcinoma by targeting CX chemokine receptor 7.

# publications[].label
Distribution of small integrin-binding ligand, N-linked glycoproteins (SIBLING) in the condylar cartilage of rat mandible.

# publications[].label
Signaling Pathways Critical for Tooth Root Formation.

# publications[].label
Author Correction: Tissue clearing of both hard and soft tissue organs with the PEGASOS method

# publications[].label
Twist1- and Twist2-haploinsufficiency results in reduced bone formation.

# publications[].label
Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis.

# publications[].label
Mineral Metabolism and its Impact on Craniofacial Bones and Teeth

# publications[].label
Dmp1 Overexpression Prevents Bone Alterations, Fgf23 Elevations and Cardiac Hypertrophy in Mice With Chronic Kidney Disease

# publications[].label
Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo.

# publications[].label
Osterix couples chondrogenesis and osteogenesis in post-natal condylar growth.

# publications[].label
TGF-Beta Receptor II Is Critical for Osteogenic Progenitor Cell Proliferation and Differentiation During Postnatal Alveolar Bone Formation.

# publications[].label
Adverse Effects of Osteocytic Constitutive Activation of -Catenin on Bone Strength and Bone Growth.

# publications[].label
DMP1-targeted Cre expression in odontoblasts and osteocytes.

# publications[].label
Osterix controls cementoblast differentiation through downregulation of Wnt-signaling via enhancing DKK1 expression.

# publications[].label
Sclerostin and DKK1 Inhibition Preserves and Augments Alveolar Bone Volume and Architecture in Rats with Alveolar Bone Loss.

# publications[].label
Osteocytes Play a Key Role in the Formation and Maintenance of Mineralized Bone

# publications[].label
[Endovascular blockade treatment of intracranial aneurysm. Report of 5 cases].

# publications[].label
Expression of dentin sialophosphoprotein in non-mineralized tissues.

# publications[].label
BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.

# publications[].label
Key proteolytic cleavage site and full-length form of DSPP.

# publications[].label
Steroid-associated hip joint collapse in bipedal emus.

# publications[].label
Chondrogenesis Defines Future Skeletal Patterns Via Cell Transdifferentiation from Chondrocytes to Bone Cells.

# publications[].label
Mechanical loading stimulates dentin matrix protein 1 (DMP1) expression in osteocytes in vivo.

# publications[].label
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass.

# publications[].label
Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice.

# publications[].label
Use of the transgenic approach to determine the role of DMP1 in phosphate regulation.

# publications[].label
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
ScxLin cells directly form a subset of chondrocytes in temporomandibular joint that are sharply increased in Dmp1-null mice.

# publications[].label
Osteoblast lineage-specific effects of notch activation in the skeleton.

# publications[].label
[Long-term safety and efficacy of high-dose cytarabine consolidation in patients with acute myeloid leukemia].

# publications[].label
Targeted Ptpn11 deletion in mice reveals the essential role of SHP2 in osteoblast differentiation and skeletal homeostasis.

# publications[].label
Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a -catenin-dependent manner.

# publications[].label
Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.

# publications[].label
Osteons and Osteocytes in Belanger's Tree Shrews (Tupaia belangeri) - a comparative study

# publications[].label
The biological function of type I receptors of bone morphogenetic protein in bone.

# publications[].label
Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.

# publications[].label
Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts.

# publications[].label
Role of the NH2 -terminal fragment of dentin sialophosphoprotein in dentinogenesis.

# publications[].label
In vitro and in vivo study on osteocyte-specific mechanical signaling pathways.

# publications[].label
Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: role of integrin1 and focal adhesion kinase signaling cues.

# publications[].label
A novel way to statistically analyze morphologic changes in Dmp1-null osteocytes.

# publications[].label
Spotlight on Tendon: Its Novel Role in Long Bone Growth and Rickets-Caused Osteosclerosis

# publications[].label
Roles of DMP1 processing in osteogenesis, dentinogenesis and chondrogenesis.

# publications[].label
Different bone remodeling levels of trabecular and cortical bone in response to changes in Wnt/-catenin signaling in mice.

# publications[].label
Complete pulpodentin complex regeneration by modulating the stiffness of biomimetic matrix.

# publications[].label
Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice.

# publications[].label
[Efficacy and safety analysis of the combination of cladribine, cytarabine, granulocyte colonystimulating factor (CLAG) regime in patients with refractory or relapsed acute myeloid leukemia].

# publications[].label
Podoplanin is dispensable for mineralized tissue formation and maintenance in the Swiss outbred mouse background.

# publications[].label
Effects of transforming growth factor beta on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts.

# publications[].label
Pathogenic role of Fgf23 in Dmp1-null mice.

# publications[].label
Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D28k.

# publications[].label
Dentin matrix protein 1 (DMP1): new and important roles for biomineralization and phosphate homeostasis.

# publications[].label
New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation.

# publications[].label
Failure to process dentin sialophosphoprotein into fragments leads to periodontal defects in mice.

# publications[].label
Expression of the BMP 2 gene during bone cell differentiation.

# publications[].label
Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion.

# publications[].label
3-dimensional visualization of implant-tissue interface with the polyethylene glycol associated solvent system tissue clearing method.

# publications[].label
Estrogen receptor- in osteocytes is important for trabecular bone formation in male mice.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Dentin matrix protein 1 and phosphate homeostasis are critical for postnatal pulp, dentin and enamel formation.

# publications[].label
Pre-odontoblasts, odontoblasts, or "odontocytes" - Reply

# publications[].label
Overexpression of Dmp1 fails to rescue the bone and dentin defects in Fam20C knockout mice.

# publications[].label
Direct transdifferentiation of ligament cells into articular chondrocytes that is regulated by Indian hedgehog (IHH) signaling and phosphate levels

# publications[].label
Osteocytes Play a Key Role in the Formation and Maintenance of Mineralized Bone

# publications[].label
Identification of full-length dentin matrix protein 1 in dentin and bone.

# publications[].label
DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease.

# publications[].label
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway.

# publications[].label
NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro.

# publications[].label
Do osteocytes contribute to phosphate homeostasis?

# publications[].label
DMP1 is essential for osteocyte formation and function.

# publications[].label
Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Nucleus-targeted Dmp1 transgene fails to rescue dental defects in Dmp1 null mice.

# publications[].label
E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation.

# publications[].label
Proteolytic processing of dentin sialophosphoprotein (DSPP) is essential to dentinogenesis.

# publications[].label
[Analysis of the safety and efficacy of 60 mgm-2d-1daunorubicin combined with standard dose of cytarabine as induction therapy in acute myeloid leukemia patients under 65 years old].

# publications[].label
Generation of a conditional null allele for Dmp1 in mouse.

# publications[].label
Sclerostin antibody (Scl-Ab) improves osteomalacia phenotype in dentin matrix protein 1(Dmp1) knockout mice with little impact on serum levels of phosphorus and FGF23.

# publications[].label
DMP1 Ablation in the Rabbit Results in Mineralization Defects and Abnormalities in Haversian Canal/Osteon Microarchitecture.

# publications[].label
Differential regulation of dentin matrix protein 1 expression during odontogenesis.

# publications[].label
Rescue of odontogenesis in Dmp1-deficient mice by targeted re-expression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo.

# publications[].label
Enamel defects and ameloblast-specific expression in Enam knock-out/lacz knock-in mice.

# publications[].label
The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor.

# publications[].label
BMP Signaling in Regulating Mesenchymal Stem Cells in Incisor Homeostasis.

# publications[].label
Unique roles of phosphorus in endochondral bone formation and osteocyte maturation.

# publications[].label
Hexa-D-arginine treatment increases 7B2PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.

# publications[].label
BMP receptor 1A determines the cell fate of the postnatal growth plate.

# publications[].label
Essential role of osterix for tooth root but not crown dentin formation.

# publications[].label
Expression of bone morphogenetic protein messenger RNA in prolonged cultures of fetal rat calvarial cells.

# publications[].label
Osteons and Osteocytes in Belanger's Tree Shrews (Tupaia belangeri) - a comparative study

# publications[].label
Identification of cis-DNA regions controlling Bmp4 expression during tooth morphogenesis in vivo.

# publications[].label
Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype.

# publications[].label
In vivo impact of a 4 bp deletion mutation in the DLX3 gene on bone development.

# publications[].label
Cartilage Oligomeric Matrix Protein Associates with Granulin-Epithelin Precursor (GEP) and Potentiates GEP-stimulated Chondrocyte Proliferation*

# publications[].label
Distribution of small integrin-binding ligand, N-linked glycoproteins (SIBLING) in the articular cartilage of the rat femoral head.

# publications[].label
A Biphasic Feature of Gli1+-Mesenchymal Progenitors during Cementogenesis That Is Positively Controlled by Wnt/-Catenin Signaling.

# publications[].label
FGF23 in skeletal modeling and remodeling.

# publications[].label
VEGF-C promotes the development of lymphatics in bone and bone loss.

# publications[].label
Expression of dentine sialophosphoprotein in mouse nasal cartilage.

# publications[].label
The specific role of FAM20C in dentinogenesis.

# publications[].label
Hypophosphatemic rickets accelerate chondrogenesis and cell trans-differentiation from TMJ chondrocytes into bone cells via a sharp increase in -catenin.

# publications[].label
Cell Lineage Tracing: Colocalization of Cell Lineage Markers with a Fluorescent Reporter.

# publications[].label
Chondrocytes Directly Transform into Bone Cells in Mandibular Condyle Growth.

# publications[].label
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype.

# publications[].label
Circling behavior developed in Dmp1 null mice is due to bone defects in the vestibular apparatus.

# publications[].label
[Evaluation of clinical characteristics, MYD88(L265P) mutation, CXCR4(WHIM) mutation and prognosis in Waldenstrm macroglobulinemia: A single center retrospective study of 93 patients].

# publications[].label
Vital Roles of -catenin in Trans-differentiation of Chondrocytes to Bone Cells.

# publications[].label
Identifying promoter elements necessary for enamelin tissue-specific expression.

# publications[].label
Tooth agenesis in a family and homozygous PAX9 mutation in exon 3: a case report.

# publications[].label
Expression of bone morphogenetic protein messenger RNAs by normal rat and human prostate and prostate cancer cells.

# publications[].label
Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development.

# publications[].label
In Situ Hybridization on Mouse Paraffin Sections Using DIG-Labeled RNA Probes.

# publications[].label
Genetic Influences on Temporomandibular Joint Development and Growth.

# publications[].label
Renal clearance measurements of electrolytes in embryonic chickens.

# publications[].label
Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model.

# publications[].label
Loss of Transferrin Receptor 1 in Osteoclast Lineage Cells Attenuates Osteoclast Energy Metabolism and Cytoskeleton Organization Resulting in a Dramatic Increase of Trabecular Bone Mass in Long Bones of Female Mice

# publications[].label
A novel auditory ossicles membrane and the development of conductive hearing loss in Dmp1-null mice.

# publications[].label
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats.

# publications[].label
Activation of Receptor Activator of Nuclear Factor-B Ligand and Matrix Metalloproteinase Production in Periodontal Fibroblasts by Endothelin Signaling.

# publications[].label
Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway.

# publications[].label
Dentinal mineralization is not limited in the mineralization front but occurs along with the entire odontoblast process.

# publications[].label
Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype.

# publications[].label
Genomic organization, chromosomal mapping, and promoter analysis of the mouse dentin sialophosphoprotein (Dspp) gene, which codes for both dentin sialoprotein and dentin phosphoprotein.

# publications[].label
Dissection of promoter control modules that direct Bmp4 expression in the epithelium-derived components of hair follicles.

# publications[].label
Studies of the DMP1 57-kDa functional domain both in vivo and in vitro.

# publications[].label
Rapid in vivo functional analysis of transgenes in mice using whole body imaging of luciferase expression.

# publications[].label
Abnormal lacuno-canalicular network and negative correlation between serum osteocalcin and Cobb angle indicate abnormal osteocyte function in adolescent idiopathic scoliosis

# publications[].label
Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Axin2+-Mesenchymal PDL Cells, Instead of K14+ Epithelial Cells, Play a Key Role in Rapid Cementum Growth.

# publications[].label
Evidence for osteocyte regulation of bone homeostasis through RANKL expression.

# publications[].label
The specific role of FAM20C in amelogenesis.

# publications[].label
Disruption of bone morphogenetic protein type IA receptor in osteoblasts impairs bone quality and bone strength in mice.

# researcherOn[].label
Chondrocyte-Derived Bone Cells Determine the Overall Pattern of TMJ Condyle and Contribute to Bone Remodeling

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Dental and Craniofacial Research

# researcherOn[].label
The Roles of Fam20c (dmp4) In Odontogenesis and Osteogenesis

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Dental and Craniofacial Research

# researcherOn[].label
DMP1 Mutations: Defects in Odontogenesis

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Dental and Craniofacial Research

# researcherOn[].label
Biphasic Roles of OSX-WNT-B-Catenin Signaling Pathway in Tooth Root Formation

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Dental and Craniofacial Research

# researcherOn[].label
Tooth Root Formation: An Emerging Signaling Pathway

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Dental and Craniofacial Research

# streetAddress
Texas A&M University College of Dentistry; Biomedical Sciences; 3302 Gaston Avenue