# positions[].organizations[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Glial-cell Line Derived Neurotrophic Factor

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Stem Cell Research - Induced Pluripotent Stem Cell

# keywords[]
Glial Cell Line-Derived Neurotrophic Factor

# keywords[]
Cyclic AMP Response Element-Binding Protein

# educationAndTraining[].organization.label
Kasturba Medical College - (Manipala, Karnataka, India)

# educationAndTraining[].organization.label
Manipal University - (Manipala, Karnataka, India)

# publications[].label
Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus.

# publications[].label
Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Progress in neuroprotective strategies for preventing epilepsy.

# publications[].label
Status epilepticus during old age is not associated with enhanced hippocampal neurogenesis.

# publications[].label
The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus.

# publications[].label
Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy.

# publications[].label
Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory.

# publications[].label
Neural stem cell- and neurogenesis-related gene expression profiles in the young and aged dentate gyrus.

# publications[].label
Stem/progenitor cell proliferation factors FGF-2, IGF-1 and VEGF exhibit early decline in the hippocampus during aging

# publications[].label
Neural Stem Cell or Human Induced Pluripotent Stem Cell-Derived GABA-ergic Progenitor Cell Grafting in an Animal Model of Chronic Temporal Lobe Epilepsy.

# publications[].label
Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus.

# publications[].label
Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus.

# publications[].label
Declined Hippocampal Neurogenesis Is Associated With Learning & Memory Impairments and Depression in a Rat Model of Gulf War Illness

# publications[].label
Repair of the injured adult hippocampus through graft-mediated modulation of the plasticity of the dentate gyrus in a rat model of temporal lobe epilepsy.

# publications[].label
Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves.

# publications[].label
Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Voluntary Running Exercise-Mediated Enhanced Neurogenesis Does Not Obliterate Retrograde Spatial Memory.

# publications[].label
Efficacy of striatal precursor cell grafting into the hippocampus for suppressing the progression of status epilepticus into chronic epilepsy

# publications[].label
Enhanced production and dendritic growth of new dentate granule cells in the middle-aged hippocampus following intracerebroventricular FGF-2 infusions.

# publications[].label
Fetal hippocampal CA3 cell grafts enriched with FGF-2 and BDNF exhibit robust long-term survival and integration and suppress aberrant mossy fiber sprouting in the injured middle-aged hippocampus.

# publications[].label
Postnatal age governs the extent of differentiation of hippocampal CA1 and CA3 subfield neural stem/progenitor cells into neurons and oligodendrocytes.

# publications[].label
Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus.

# publications[].label
Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy.

# publications[].label
Efficacy of Intrahippocampal Grafting of Subventricular Zone-Derived Neural Stem Cells for Easing Status Epilepticus-Induced Temporal Lobe Epilepsy and Related Comorbidities

# publications[].label
Neurogenesis response of middle-aged hippocampus to acute seizure activity.

# publications[].label
Neural Stem Cell Therapy for Easing Status Epilepticus Induced Hippocampus Dysfunction and Chronic Temporal Lobe Epilepsy

# publications[].label
Newly born cells in the ageing dentate gyrus display normal migration, survival and neuronal fate choice but endure retarded early maturation.

# publications[].label
Mild Traumatic Brain Injury Induced Through an Exposure to Blast Shock Waves Causes Lasting Hippocampus-Dependent and Hippocampus-Independent Memory Dysfunction and Depression

# publications[].label
Enduring survival of new neurons born at early post-status epilepticus and during chronic epilepsy in the rat dentate gyrus

# publications[].label
Grafted Subventricular Zone Neural Stem Cells Display Robust Engraftment and Similar Differentiation Properties and Form New Neurogenic Niches in the Young and Aged Hippocampus.

# publications[].label
Incorporation of embryonic CA3 cell grafts into the adult hippocampus at 4-months after injury: effects of combined neurotrophic supplementation and caspase inhibition.

# publications[].label
Resveratrol Treatment after Status Epilepticus Restrains Neurodegeneration and Abnormal Neurogenesis with Suppression of Oxidative Stress and Inflammation.

# publications[].label
Deafferentation enhances neurogenesis in the young and middle aged hippocampus but not in the aged hippocampus.

# publications[].label
Strategies for promoting anti-seizure effects of hippocampal fetal cells grafted into the hippocampus of rats exhibiting chronic temporal lobe epilepsy.

# publications[].label
Differential susceptibility of interneurons expressing neuropeptide Y or parvalbumin in the aged hippocampus to acute seizure activity.

# publications[].label
Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation.

# publications[].label
Restoration of calbindin after fetal hippocampal CA3 cell grafting into the injured hippocampus in a rat model of temporal lobe epilepsy.

# publications[].label
Acute Seizures in Old Age Leads to a Greater Loss of CA1 Pyramidal Neurons, an Increased Propensity for Developing Chronic TLE and a Severe Cognitive Dysfunction.

# publications[].label
Behavior of hippocampal stem/progenitor cells following grafting into the injured aged hippocampus.

# publications[].label
Neural stem cell grafting counteracts hippocampal injury-mediated impairments in mood, memory, and neurogenesis.

# publications[].label
Neural Stem Cells in the Adult Brain: Altered Activity in Aging, Alzheimers Disease, Mood Disorders and Epilepsy

# publications[].label
Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy.

# publications[].label
Curcumin treatment leads to better cognitive and mood function in a model of Gulf War Illness with enhanced neurogenesis, and alleviation of inflammation and mitochondrial dysfunction in the hippocampus.

# publications[].label
Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury.

# publications[].label
Medial Ganglionic Eminence Precursor Cell Grafting Diminishes Spontaneous Seizures and Improves Memory Function in a Rat Model of Temporal Lobe Epilepsy

# publications[].label
Stem/progenitor cell proliferation factors FGF-2, IGF-1, and VEGF exhibit early decline during the course of aging in the hippocampus: role of astrocytes.

# publications[].label
Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy.

# publications[].label
Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness.

# publications[].label
Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age.

# publications[].label
Grafting of GABAergic Progenitors From Human iPSCs Into the Hippocampus After Status Epilepticus Curbs Spontaneous Seizures and Prevents Cognitive, Memory, and Mood Impairments

# publications[].label
Links Between Loss of Reelin+ Interneurons, Frequency of Spontaneous Seizures, and Memory Impairments in Chronic Temporal Lobe Epilepsy

# publications[].label
Hippocampal Neural Stem Cell Grafting after Status Epilepticus Alleviates Chronic Epilepsy and Abnormal Plasticity, and Maintains Better Memory and Mood Function.

# publications[].label
Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore GDNF expression in a rat model of chronic temporal lobe epilepsy.

# publications[].label
Chronic Oxidative Stress, Mitochondrial Dysfunction, Nrf2 Activation and Inflammation in the Hippocampus Accompany Heightened Systemic Inflammation and Oxidative Stress in an Animal Model of Gulf War Illness.

# publications[].label
Concise review: prospects of stem cell therapy for temporal lobe epilepsy.

# publications[].label
Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy.

# publications[].label
Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate-induced injury is lost by middle age.

# publications[].label
Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus.

# publications[].label
Neural stem cell grafting in an animal model of chronic temporal lobe epilepsy.

# publications[].label
Moderate, intermittent voluntary exercise in a model of Gulf War Illness improves cognitive and mood function with alleviation of activated microglia and astrocytes, and enhanced neurogenesis in the hippocampus.

# publications[].label
Administration of TSG-6 improves memory after traumatic brain injury in mice.

# publications[].label
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness.

# publications[].label
A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology.

# publications[].label
Unilateral Moderate Controlled Cortical Impact Traumatic Brain Injury Induces Enduring Deficits in Spatial, Object Location, Object Recognition and Pattern Separation Memory, and Mood Function

# publications[].label
Parvalbumin and neuropeptide Y expressing hippocampal GABA-ergic inhibitory interneuron numbers decline in a model of Gulf War illness.

# publications[].label
Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus.

# publications[].label
Hippocampal interneuron damage, spontaneous recurrent seizures, mossy fiber sprouting, and neurosteroid efficacy in the rat pilocarpine model of temporal lobe epilepsy

# publications[].label
Moderate Running Exercise Improves Cognitive, Memory, and Mood Function With Increased Neurogenesis in a Gulf War Illness Model

# publications[].label
Implications of decreased hippocampal neurogenesis in chronic temporal lobe epilepsy.

# publications[].label
Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness.

# publications[].label
Neurodegeneration, spontaneous recurrent motor seizures and aberrant mossy fiber sprouting in a model of temporal lobe epilepsy using F344 rats

# streetAddress
Texas A&M Health Science Center; Regenerative Medicine; 1114 TAMUS

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine