# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# keywords[]
Cyclic AMP Response Element-Binding Protein

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Cyclic AMP Response Element-Binding Protein

# keywords[]
Networking And Information Technology R&d

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Cyclic AMP Response Element-Binding Protein

# keywords[]
Networking And Information Technology R&d

# keywords[]
Cyclic AMP Response Element-Binding Protein

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Networking And Information Technology R&d

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# educationAndTraining[].organization.label
The University of Texas at Austin - (Austin, Texas, United States)

# publications[].label
Mechanisms underlying fictive feeding in aplysia: coupling between a large neuron with plateau potentials activity and a spiking neuron.

# publications[].label
Dynamics of a minimal model of interlocked positive and negative feedback loops of transcriptional regulation by cAMP-response element binding proteins.

# publications[].label
Differential effects of cAMP and serotonin on membrane current, action-potential duration, and excitability in somata of pleural sensory neurons of Aplysia.

# publications[].label
Neural and molecular bases of nonassociative and associative learning in Aplysia.

# publications[].label
Computational analysis of memory consolidation following inhibitory avoidance (IA) training in adult and infant rats: critical roles of CaMKII and MeCP2

# publications[].label
Neuronal and network determinants of simple and higher-order features of associative learning: experimental and modeling approaches.

# publications[].label
Modeling transcriptional control in gene networks--methods, recent results, and future directions.

# publications[].label
Extending in vitro conditioning in Aplysia to analyze operant and classical processes in the same preparation.

# publications[].label
Simulator for neural networks and action potentials: description and application.

# publications[].label
GEOMETRY, ACTIVITY-DEPENDENT MECHANISMS, MEMBRANE KINETICS AND CHANNEL DENSITY DISTRIBUTION INTERPLAY IN SINGLE NEURON PLASTICITY: A COMPUTATIONAL STUDY

# publications[].label
Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model.

# publications[].label
Synaptic plasticity at crayfish neuromuscular junctions: facilitation and augmentation.

# publications[].label
Control of multistability in ring circuits of oscillators.

# publications[].label
Frequency selectivity, multistability, and oscillations emerge from models of genetic regulatory systems.

# publications[].label
Specific Plasticity Loci and Their Synergism Mediate Operant Conditioning.

# publications[].label
Bifurcation and singularity analysis of a molecular network for the induction of long-term memory.

# publications[].label
The sensitivity of memory consolidation and reconsolidation to inhibitors of protein synthesis and kinases: computational analysis.

# publications[].label
Unique Configurations of Compression and Truncation of Neuronal Activity Underlie l-DOPA-Induced Selection of Motor Patterns in Aplysia.

# publications[].label
Modeling suggests combined-drug treatments for disorders impairing synaptic plasticity via shared signaling pathways.

# publications[].label
A model of the roles of essential kinases in the induction and expression of late long-term potentiation.

# publications[].label
GEOMETRY, ACTIVITY-DEPENDENT MECHANISMS, MEMBRANE KINETICS AND CHANNEL DENSITY DISTRIBUTION INTERPLAY IN SINGLE NEURON PLASTICITY: A COMPUTATIONAL STUDY

# publications[].label
In vitro analog of operant conditioning in aplysia. II. Modifications of the functional dynamics of an identified neuron contribute to motor pattern selection.

# publications[].label
Reinforcement in an in vitro analog of appetitive classical conditioning of feeding behavior in Aplysia: blockade by a dopamine antagonist.

# publications[].label
Modulation of fictive feeding by dopamine and serotonin in aplysia.

# publications[].label
Experimental and Computational Analyses of a Central Pattern Generator Underlying Aspects of Feeding Behaviour of Aplysia

# publications[].label
Molecular Constraints on Synaptic Tagging and Maintenance of Long-Term  Potentiation: A Predictive Model

# publications[].label
Chapter 15 Comparison of Operant and Classical Conditioning of Feeding Behavior in Aplysia

# publications[].label
Deficit in long-term synaptic plasticity is rescued by a computationally predicted stimulus protocol.

# publications[].label
Spontaneous activity of dopaminergic retinal neurons.

# publications[].label
Computational analysis of memory consolidation following inhibitory avoidance (IA) training in adult and infant rats: Critical roles of CaMKII and MeCP2.

# publications[].label
Paradoxical LTP maintenance with inhibition of protein synthesis and the  proteasome suggests a novel protein synthesis requirement for early LTP  reversal

# publications[].label
Correlation between activity in neuron B52 and two features of fictive feeding in Aplysia.

# publications[].label
Nonlinear dynamics in a model neuron provide a novel mechanism for transient synaptic inputs to produce long-term alterations of postsynaptic activity.

# publications[].label
Modulation of a cAMP/protein kinase A cascade by protein kinase C in sensory neurons of Aplysia.

# publications[].label
Burst-induced synaptic depression and its modulation contribute to information transfer at Aplysia sensorimotor synapses: empirical and computational analyses.

# publications[].label
Computational model of the distributed representation of operant reward memory: combinatoric engagement of intrinsic and synaptic plasticity mechanisms.

# publications[].label
Simulator for neural networks and action potentials.

# publications[].label
Reduction of voltage-activated K+ currents by forskolin is not mediated via cAMP in pleural sensory neurons of Aplysia.

# publications[].label
Computational study of enhanced excitability in Hermissenda: membrane conductances modulated by 5-HT.

# publications[].label
Computational model of a positive BDNF feedback loop in hippocampal neurons following inhibitory avoidance training.

# publications[].label
Activators of protein kinase C mimic serotonin-induced modulation of a voltage-dependent potassium current in pleural sensory neurons of Aplysia.

# publications[].label
Feeding behavior of Aplysia: a model system for comparing cellular mechanisms of classical and operant conditioning.

# publications[].label
Simulation of Drosophila circadian oscillations, mutations, and light responses by a model with VRI, PDP-1, and CLK.

# publications[].label
Biphasic Regulation of p38 MAPK by Serotonin Contributes to the Efficacy of Stimulus Protocols That Induce Long-Term Synaptic Facilitation.

# publications[].label
Comparing Theories for the Maintenance of Late LTP and Long-Term Memory: Computational Analysis of the Roles of Kinase Feedback Pathways and Synaptic Reactivation.

# publications[].label
A learning rule based on empirically-derived activity-dependent neuromodulation supports operant conditioning in a small network

# publications[].label
Desensitization of postsynaptic glutamate receptors contributes to high-frequency homosynaptic depression of aplysia sensorimotor connections.

# publications[].label
Computational model of touch sensory cells (T Cells) of the leech: role of the afterhyperpolarization (AHP) in activity-dependent conduction failure.

# publications[].label
Study on Simulator for Biological Neural Networks

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Comparing Theories for the Maintenance of Late LTP and Long-Term Memory:  Computational Analysis of the Roles of Kinase Feedback Pathways and Synaptic  Reactivation

# publications[].label
Ionic conductance mechanisms contributing to the electrophysiological properties of neurons.

# publications[].label
Network model for visually mediated ciliary locomotion in Hermissenda

# publications[].label
Paradoxical LTP maintenance with inhibition of protein synthesis and the proteasome suggests a novel protein synthesis requirement for early LTP reversal.

# publications[].label
Neuronal population activity dynamics reveal a low-dimensional signature of operant learning in Aplysia.

# publications[].label
Dopaminergic synapses mediate neuronal changes in an analogue of operant conditioning.

# publications[].label
Classical conditioning analog enhanced acetylcholine responses but reduced excitability of an identified neuron.

# publications[].label
Classical conditioning of feeding in Aplysia: I. Behavioral analysis.

# publications[].label
Molecular mechanisms underlying a cellular analog of operant reward learning.

# publications[].label
cAMP-independent effects of 8-(4-parachlorophenylthio)-cyclic AMP on spike duration and membrane currents in pleural sensory neurons of Aplysia.

# publications[].label
Voltage-clamp analysis and computational model of dopaminergic neurons from mouse retina.

# publications[].label
The normal accumulation of facilitation during presynaptic inhibition.

# publications[].label
Chapter 7 Dynamical Properties of Excitable Membranes

# publications[].label
Bistability and its regulation by serotonin in the endogenously bursting neuron R15 in Aplysia.

# publications[].label
Simulations suggest pharmacological methods for rescuing long-term potentiation.

# publications[].label
Interlinked Dual-Time Feedback Loops can Enhance Robustness to  Stochasticity and Persistence of Memory

# publications[].label
Contingent-dependent enhancement of rhythmic motor patterns: an in vitro analog of operant conditioning.

# publications[].label
Simulation of Drosophila Circadian Oscillations, Mutations, and Light  Responses by a Model with VRI, PDP-1, and CLK

# publications[].label
Changes in neuronal excitability serve as a mechanism of long-term memory for operant conditioning.

# publications[].label
Involvement of protein kinase C in serotonin-induced spike broadening and synaptic facilitation in sensorimotor connections of Aplysia.

# publications[].label
Analysis of the modulation by serotonin of a voltage-dependent potassium current in sensory neurons of Aplysia.

# publications[].label
Dynamic properties of regulatory motifs associated with induction of three temporal domains of memory in aplysia.

# publications[].label
Teaching basic principles of neuroscience with computer simulations.

# publications[].label
Interlinked dual-time feedback loops can enhance robustness to stochasticity and persistence of memory.

# publications[].label
Current- and voltage-clamp recordings and computer simulations of Kenyon cells in the honeybee.

# publications[].label
Specific plasticity loci and their synergism mediate operant conditioning

# publications[].label
Classical and operant conditioning differentially modify the intrinsic properties of an identified neuron.

# publications[].label
Role of A-type K+ channels in spike broadening observed in soma and axon of Hermissenda type-B photoreceptors: a simulation study.

# publications[].label
Synaptic plasticity at crayfish neuromuscular junctions: presynaptic inhibition.

# publications[].label
Comparing Theories for the Maintenance of Late LTP and Long-Term Memory: Computational Analysis of the Roles of Kinase Feedback Pathways and Synaptic Reactivation

# publications[].label
Computational design of enhanced learning protocols.

# publications[].label
Small networks of empirically derived adaptive elements simulate some higher-order features of classical conditioning

# publications[].label
Inferring neuronal network functional connectivity with directed information.

# publications[].label
Research and Implementation of Computer Simulation System for Neural Networks

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Genesis of bursting activity: Role of inhibitory constraints on persistent Na+ currents

# publications[].label
Neural Mechanisms Underlying Sensitization of a Defensive Reflex in Aplysia.

# publications[].label
Effects of macromolecular transport and stochastic fluctuations on dynamics of genetic regulatory systems.

# publications[].label
Classical conditioning of feeding in Aplysia: II. Neurophysiological correlates.

# publications[].label
Phase response characteristics of model neurons determine which patterns are expressed in a ring circuit model of gait generation.

# publications[].label
In vitro analog of classical conditioning of feeding behavior in aplysia.

# publications[].label
Operant reward learning in Aplysia: neuronal correlates and mechanisms.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
How can memories last for days, years, or a lifetime? Proposed mechanisms for maintaining synaptic potentiation and memory.

# publications[].label
Intracellular recordings from crustacean motor axons during presynaptic inhibition.

# publications[].label
Analysis of the effects of modulatory agents on a modeled bursting neuron: dynamic interactions between voltage and calcium dependent systems.

# publications[].label
Computational analyses of synergism in small molecular network motifs.

# publications[].label
Simulations Suggest Pharmacological Methods for Rescuing Long-Term  Potentiation

# publications[].label
Quantal mechanism of long-term synaptic potentiation.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Multiple modes of activity in a model neuron suggest a novel mechanism for the effects of neuromodulators.

# publications[].label
Differential effects of 4-aminopyridine, serotonin, and phorbol esters on facilitation of sensorimotor connections in Aplysia.

# publications[].label
A Model of the Roles of Essential Kinases in the Induction and  Expression of Late Long-Term Potentiation

# publications[].label
Identification and characterization of catecholaminergic neuron B65, which initiates and modifies patterned activity in the buccal ganglia of Aplysia.

# publications[].label
Chapter 6 Modeling and Analysis of Intracellular Signaling Pathways

# publications[].label
Modulatory effects of serotonin, FMRFamide, and myomodulin on the duration of action potentials, excitability, and membrane currents in tail sensory neurons of Aplysia.

# publications[].label
Estimation of single-neuron model parameters from spike train data

# publications[].label
Serotonergic modulation of two potassium currents in the pleural sensory neurons of Aplysia.

# publications[].label
Reduced models of the circadian oscillators in Neurospora crassa and Drosophila melanogaster illustrate mechanistic similarities.

# publications[].label
Multimodal behavior in a four neuron ring circuit: mode switching.

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Mathematical model of cellular mechanisms contributing to presynaptic facilitation.

# publications[].label
Short-Term Plasticity in a Computational Model of the Tail-Withdrawal Circuit in Aplysia.

# publications[].label
Neuronal population activity dynamics reveal a low-dimensional signature of operant learning

# publications[].label
Computational Model of a Central Pattern Generator

# publications[].label
Computational Capabilities of Single Neurons: Relationship to Simple Forms of Associative and Nonassociative Learning in Aplysia

# publications[].label
Nonlinear and Chaotic Dynamics in a Model Neuron Serve as Putative Memory Mechanisms

# publications[].label
Modeling Suggests Combined-Drug Treatments for Disorders Impairing  Synaptic Plasticity via Shared Signaling Pathways

# publications[].label
Autaptic excitation contributes to bistability and rhythmicity in the neural circuit for feeding in Aplysia

# publications[].label
Gait generation characterized by the phase sensitive properties of synaptically coupled neurons

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
In vitro analog of operant conditioning in aplysia. I. Contingent reinforcement modifies the functional dynamics of an identified neuron.

# publications[].label
Computational model of the serotonergic modulation of sensory neurons in Aplysia.

# publications[].label
Contribution of PKC to the maintenance of 5-HT-induced short-term facilitation at sensorimotor synapses of Aplysia.

# publications[].label
Modeling circadian oscillations with interlocking positive and negative feedback loops.

# publications[].label
Bistable MAP kinase activity: a plausible mechanism contributing to maintenance of late long-term potentiation.

# publications[].label
Modeling interactions between electrical activity and second-messenger cascades in Aplysia neuron R15.

# publications[].label
Role of Nonlinear Dynamical Properties of a Modelled Bursting Neuron in Information Processing and Storage

# publications[].label
Bistable MAP Kinase Activity: A Plausible Mechanism Contributing to  Maintenance of Late Long-Term Potentiation

# publications[].label
A computational study of the role of spike broadening in synaptic facilitation of Hermissenda.

# publications[].label
Chapter 7 Computational Analyses of Learning Networks

# publications[].label
Chapter 14 Mathematical Modeling and Analysis of Intracellular Signaling Pathways

# publications[].label
How Can Memories Last for Days, Years, or a Lifetime? Proposed  Mechanisms for Maintaining Synaptic Potentiation and Memory

# publications[].label
The role of interneurons in controlling the tail-withdrawal reflex in Aplysia: a network model.

# publications[].label
A reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillator.

# publications[].label
Role of calcium-calmodulin-dependent protein kinase II in modulation of sensorimotor synapses in Aplysia.

# publications[].label
Comparison of Operant and Classical Conditioning of Feeding Behavior in Aplysia

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine

# schools[]
Texas A&M University Naresh K. Vashisht College of Medicine