# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# overview
Research in the Chapkin lab focuses on dietary/microbial modulators related to the prevention of cancer and chronic inflammatory diseases.

Our central goal is to (1) understand cancer chemoprevention at a fundamental level, and (2) to test pharmaceutical agents in combination with dietary/microbial (countermeasures to the Western diet) to more effectively improve gut health and reduce systemic chronic inflammation. Since diet influences gut microbiota composition and metabolite production, to unravel the interrelationships among gut health and the structure of the gut microbial ecosystem, we are in the process of evaluating (using transgenic mouse, Drosophila models and humans) how the gut microbiome modulates intestinal cells, innate immune cells and tumors. As part of this endeavor, we are modeling at the molecular level the dynamic relationship between diet and gut microbe-derived metabolites which modulate chronic inflammation and the hierarchical cellular organization of the intestine, e.g., stem cell niche.

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Receptors, Tumor Necrosis Factor, Member 25

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
Suppressor Of Cytokine Signaling 3 Protein

# keywords[]
Single-Strand Specific DNA And RNA Endonucleases

# keywords[]
Cyclic Nucleotide Phosphodiesterases, Type 4

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
Stem Cell Research - Nonembryonic - Human

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Child Overweight; Time Varying Effect Models

# keywords[]
Stem Cell Research - Nonembryonic - Human

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
Nuclear Receptor Subfamily 4, Group A, Member 1

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# educationAndTraining[].organization.label
University of Guelph - (Guelph, Ontario, Canada)

# educationAndTraining[].organization.label
University of California, Davis - (Davis, California, United States)

# educationAndTraining[].organization.label
University of Guelph - (Guelph, Ontario, Canada)

# awardsAndHonors[].label
Mary Swartz Rose Senior Investigator Award

# publications[].label
A Novel Role for Nutrition in the Alteration of Functional Microdomains on the Cell Surface

# publications[].label
Biography of Joanne R Lupton (1944-2020).

# publications[].label
Nutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology.

# publications[].label
Fish oil protects against intestinal oxidative DNA damage

# publications[].label
ALTERED PHOSPHOLIPID AND FATTY-ACID COMPOSITIONS IN SERUM AND HIGH-DENSITY LIPOPROTEINS OF RENAL PATIENTS ON MAINTENANCE HEMODIALYSIS

# publications[].label
Detection of putative colon cancer biomarkers in exfoliated colonocytes.

# publications[].label
scTenifoldXct: A semi-supervised method for predicting cell-cell interactions and mapping cellular communication graphs.

# publications[].label
Dietary gamma-linolenic acid modulates macrophage-vascular smooth muscle cell interactions. Evidence for a macrophage-derived soluble factor that downregulates DNA synthesis in smooth muscle cells.

# publications[].label
Influence of dietary n-3 fatty acids on macrophage glycerophospholipid molecular species and peptidoleukotriene synthesis.

# publications[].label
Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation.

# publications[].label
Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes.

# publications[].label
DHA alters EGFR spatiotemporal dynamics to suppress signal transduction

# publications[].label
Purified dietary n-3 polyunsaturated fatty acids alter diacylglycerol mass and molecular species composition in concanavalin A-stimulated murine splenocytes.

# publications[].label
Morphodensitometric analysis of protein kinase C beta(II) expression in rat colon: modulation by diet and relation to in situ cell proliferation and apoptosis.

# publications[].label
A high legume low glycemic index diet improves serum lipid profiles in men.

# publications[].label
Fish oil enhances targeted apoptosis during colon tumor initiation by down regulating Bcl-2.

# publications[].label
Dietary fish oil and butyrate may protect against colon cancer by inducing mitochondria-dependent apoptosis in the promotion stage of carcinogenesis

# publications[].label
Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
The induction of proliferative vascular smooth muscle cell phenotypes by benzo(a)pyrene is characterized by up-regulation of inositol phospholipid metabolism and c-Ha-ras gene expression.

# publications[].label
Establishment of a multicomponent dietary bioactive human equivalent dose to delete damaged Lgr5+ stem cells using a mouse colon tumor initiation model.

# publications[].label
Model-based study of the Effectiveness of Reporting Lists of Small Feature Sets using RNA-Seq Data

# publications[].publisher
Association for Computing Machinery (ACM)

# publications[].label
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach.

# publications[].label
Analysis of epidermal growth factor receptor dimerization by BS cross-linking.

# publications[].label
Simulated galactic cosmic radiation enhances colon cancer in the rat, which is mediated by changes in gene expression that are influenced by dietary intervention.

# publications[].label
Involvement of Intestinal Epithelium Aryl Hydrocarbon Receptor Expression and 3, 3'-Diindolylmethane in Colonic Tertiary Lymphoid Tissue Formation.

# publications[].label
Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects.

# publications[].label
Diet and carcinogen alter luminal butyrate concentration and intracellular pH in isolated rat colonocytes.

# publications[].label
Short chain fatty acids exhibit selective estrogen receptor downregulator (SERD) activity in breast cancer.

# publications[].label
Effect of diet on colonic-programmed cell death: molecular mechanism of action.

# publications[].label
The chemopreventive action of quercetin decreases the number of high multiplicity aberrant crypt foci (ACF), reduces proliferation, and increases apoptosis in rat colonocytes.

# publications[].label
Comparing automatic and manual image processing in FLARE assay analysis for colon carcinogenesis

# publications[].label
n3 PUFAs reduce mouse CD4+ T-cell ex vivo polarization into Th17 cells.

# publications[].label
Dietary eicosapentaenoic acid modulates CTLA-4 expression in murine CD4+ T-cells.

# publications[].label
Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production.

# publications[].publisher
The American Association of Immunologists

# publications[].label
DIETARY FIBER ALTERS STEADY-STATE LEVELS OF PKC ISOZYMES IN RAT COLON

# publications[].label
Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles.

# publications[].label
Abstract P016: Endomembranes accumulate unesterified cholesterol in Apc mutant models and humans with CRC as assessed by RNAseq and confocal microscopy

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Homeostatic responses of colonic LGR5+ stem cells following acute in vivo exposure to a genotoxic carcinogen.

# publications[].label
Aryl Hydrocarbon Receptor Activity in Intestinal Epithelial Cells in the Formation of Colonic Tertiary Lymphoid Tissues.

# publications[].label
MODULATION OF INTERMEDIATE BIOMARKERS OF COLON-CANCER BY DIETARY-FAT, FIBER AND CARCINOGEN IN RAT COLONOCYTES

# publications[].label
Fish oil enhances targeted apoptosis of colonocytes within the first 12 hours of carcinogen exposure and results in lower levels of DNA damage compared to corn oil.

# publications[].label
n-3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation.

# publications[].label
Reduced iNOS and COX-2 levels are associated with enhanced apoptosis induced by grapefruit pulp and limonin in rat colonocytes

# publications[].label
Dietary fat and fiber interact to uniquely modify global histone post-translational epigenetic programming in a rat colon cancer progression model.

# publications[].label
Infant nutrition and the microbiome: Systems biology approaches to uncovering host-microbe interactions

# publications[].label
The Model-Based Study of the Effectiveness of Reporting Lists of Small Feature Sets Using RNA-Seq Data.

# publications[].label
ALTERATIONS OF EPIDERMAL LIPID-METABOLISM IN ESSENTIAL FATTY-ACID DEFICIENT GUINEA-PIGS

# publications[].label
Protecting the environment through insect farming as a means to produce protein for use as livestock, poultry, and aquaculture feed

# publications[].label
Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis.

# publications[].label
Metabolism of essential fatty acids by human epidermal enzyme preparations: evidence of chain elongation.

# publications[].label
2 Clinical Effects of n-3 PUFA Supplementation in Human Health and Inflammatory Diseases

# publications[].label
Effects of dietary n-3 and n-6 polyunsaturated fatty acids on macrophage phospholipid classes and subclasses.

# publications[].label
Localization of protein kinase C isozymes in rat colon.

# publications[].label
Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes.

# publications[].label
HUMAN EPIDERMAL ENZYME PREPARATIONS CAN ELONGATE GAMMALINOLEIC ACID (18-3,N6) INTO GAMMAHOMOLINOLENIC ACID (20-3,N6)

# publications[].label
Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.

# publications[].label
Characterization of the effectiveness of reporting lists of small feature sets relative to the accuracy of the prior biological knowledge.

# publications[].label
MicroRNA-223 is a crucial mediator of PPAR-regulated alternative macrophage activation.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Omega-3 Fatty Acids in Cancer Prevention and Control: A Membrane Perspective

# publications[].label
EFFECTS OF N-3 FATTY-ACIDS ON INTERLEUKIN-2 DEPENDENT AND INDEPENDENT SPLENOCYTE FUNCTION

# publications[].label
Insight into hypoxia tolerance in cowpea bruchid: metabolic repression and heat shock protein regulation via hypoxia-inducible factor 1.

# publications[].label
Colonic cell proliferation and apoptosis in rodent species. Modulation by diet.

# publications[].label
Dietary (n-3) polyunsaturated fatty acids suppress murine lymphoproliferation, interleukin-2 secretion, and the formation of diacylglycerol and ceramide.

# publications[].label
Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships.

# publications[].label
Chemoprotective fish oil/pectin diets temporally alter gene expression profiles in exfoliated colonocytes

# publications[].label
Maintenance of the colonic epithelial is regulated by small changes in proliferation and apoptosis and is affected by fiber and carcinogen.

# publications[].label
Response to oxidative stress may not explain the differential cancer susceptibility of the small and large intestine

# publications[].label
Functional link between plasma membrane spatiotemporal dynamics, cancer biology, and dietary membrane-altering agents.

# publications[].label
Clinical Effects of n-3 PUFA Supplementation in Human Health and Inflammatory Diseases

# publications[].label
Changes in apoptosis rather than cell proliferation best explain the effect of fat and fiber on colon carcinogenesis.

# publications[].label
Comparative effects of diet and carcinogen on microRNA expression in the stem cell niche of the mouse colonic crypt.

# publications[].label
A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells.

# publications[].label
Synthesis of colonic membrane phospholipids is altered during tumorigenesis and is affected by diet.

# publications[].label
A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response.

# publications[].label
A novel role for nutrition in the alteration of functional microdomains on the cell surface.

# publications[].label
REMODELING OF MOUSE KIDNEY PHOSPHOLIPID CLASSES AND SUBCLASSES BY DIET

# publications[].label
Ability of 15-hydroxyeicosatrienoic acid (15-OH-20:3) to modulate macrophage arachidonic acid metabolism.

# publications[].label
Dietary fat and fiber interactively modulate apoptosis and mitochondrial bioenergetic profiles in mouse colon in a site-specific manner.

# publications[].label
GENERATION OF NOVEL METABOLITES OF DIETARY LINOLEIC-ACID (18-2N6) BY GUINEA-PIG EPIDERMIS

# publications[].label
Extinction scenarios in evolutionary processes: A Multinomial   Wright-Fisher approach

# publications[].label
The microbiota-derived metabolite indole decreases mucosal inflammation and injury in a murine model of NSAID enteropathy.

# publications[].label
Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.

# publications[].label
Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation.

# publications[].label
Utilization of gammalinolenic acid by mouse peritoneal macrophages.

# publications[].label
A rapid RT-PCR method for detection of intact RNA in formalin-fixed paraffin-embedded tissues.

# publications[].label
Robert Chapkin on Relationships Between the Gut Microbiome, Diet, and Colorectal Cancer.

# publications[].label
Protein kinase C betaII and TGFbetaRII in omega-3 fatty acid-mediated inhibition of colon carcinogenesis.

# publications[].label
Fecal microbiome and metabolites differ between breast and formula-fed human infants

# publications[].label
Effects of dietary n-3 polyunsaturated fatty acids on T-cell membrane composition and function.

# publications[].label
Omega-3 fatty acids, membrane remodeling and cancer prevention.

# publications[].label
Shaping functional gut microbiota using dietary bioactives to reduce colon cancer risk.

# publications[].label
Effects of purified dietary n-3 ethyl esters on murine T lymphocyte function.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Ameliorative effect of dietary fish oil on carcinogen induced over-expression of colonic protein kinase C beta II in the rat.

# publications[].label
Incorporation of a dietary omega 3 fatty acid impairs murine macrophage responses to Mycobacterium tuberculosis.

# publications[].label
Noninvasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4(+) T cell metabolic activation.

# publications[].label
Cross-talk between SIM2s and NFB regulates cyclooxygenase 2 expression in breast cancer.

# publications[].label
Testing for spatial correlation in nonstationary binary data, with application to aberrant crypt foci in colon carcinogenesis.

# publications[].label
A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis.

# publications[].label
n-3 polyunsaturated fatty acids promote apoptosis in oxidatively stressed transgenic mouse models

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary fish oil does not affect proliferation or cytokine production in marine CD4(+) T cells polarized toward a Th2 phenotype in vitro

# publications[].label
Oncogenic ras alters sensitivity of mouse colonocytes to butyrate and fatty acid mediated growth arrest and apoptosis.

# publications[].label
Dietary fish oil may protect against colon cancer by altering mitochondrial function thereby creating a permissive environment for butyrate-induced apoptosis

# publications[].label
ALTERATION OF MOUSE PERITONEAL MACROPHAGE PHOSPHOLIPID MOLECULAR-SPECIES BY DIETARY FISH OIL

# publications[].label
Butyrate alters activity of specific cAMP-receptor proteins in a transgenic mouse colonic cell line.

# publications[].label
Flavonoids: structure-function and mechanisms of action and opportunities for drug development.

# publications[].label
Reappraisal of the essential fatty acids

# publications[].label
Adiponectin is required for maintaining normal body temperature in a cold environment.

# publications[].label
Inhibitory effects of omega-3 fatty acids on injury-induced epidermal growth factor receptor transactivation contribute to delayed wound healing.

# publications[].label
Data describing the effects of dietary bioactive agents on colonic stem cell microRNA and mRNA expression.

# publications[].label
Wheat bran diet reduces tumor incidence in a rat model of colon cancer independent of effects on distal luminal butyrate concentrations.

# publications[].label
Natural and irradiated grapefruit pulp and their functional compounds suppress aberrant crypt foci and colonocyte proliferation

# publications[].label
Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids.

# publications[].label
Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Diet and carcinogen alter luminal butyrate concentration and intracellular pH in colonocytes.

# publications[].label
Ah receptor ligands and their impacts on gut resilience: structure-activity effects.

# publications[].label
Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells.

# publications[].label
Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Suppression of colon carcinogenesis by bioactive compounds in grapefruit.

# publications[].label
Effect of dietary linseed oil on tumoricidal activity and eicosanoid production in murine macrophages.

# publications[].label
Dietary alteration of reactive oxygen species (ROS) and antioxidant enzyme activity in rat colonocytes is age-dependent

# publications[].label
Relationship among colonocyte proliferation, differentiation, and apoptosis as a function of diet and carcinogen.

# publications[].label
A diet containing fish oil and pectin ameliorates radiation-enhanced colon carcinogenesis by suppression of PPAR(delta) and PGE synthase-2 (PGES(2))and elevation of PGE(3)

# publications[].label
Classification of diet-modulated gene signatures at the colon cancer initiation and progression stages.

# publications[].label
Fish oil and pectin enhance apoptosis in irradiated rat colonocytes via suppression of PGE synthase-2 and Wnt pathway

# publications[].label
THE EFFECT OF BORAGE OIL SUPPLEMENTATION ON HUMAN PLATELET-AGGREGATION, THROMBOXANE-B(2), PROSTAGLANDIN-E(1) AND PROSTAGLANDIN-E(2) FORMATION

# publications[].label
Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine.

# publications[].label
Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study.

# publications[].label
Importance of dietary gamma-linolenic acid in human health and nutrition.

# publications[].label
CONDITIONING-BASED MODEL FOR THE REGULATORY ACTIVITIES OF microRNAs IN SPECIFIC DIETARY CONTEXTS

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Inability of skin enzyme preparations to biosynthesize arachidonic acid from linoleic acid.

# publications[].label
Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans.

# publications[].label
Graphical Dirichlet Process for Clustering Non-Exchangeable Grouped Data

# publications[].label
Estradiol Has Differential Effects on Acute Colonic Inflammation in the Presence and Absence of Estrogen Receptor  Expression.

# publications[].label
Targeting the aryl hydrocarbon receptor in stem cells to improve the use of food as medicine.

# publications[].label
Combination of fish oil and pectin suppressed beta-catenin nuclear translocation, an important molecular event in colon carcinogenesis

# publications[].label
Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
Docosahexaenoic acid suppresses function of the CD28 costimulatory membrane receptor in primary murine and Jurkat T cells.

# publications[].label
Differential activation of NF-kappa B in colonic mucosa of DSS-challenged rats consuming fermentable fiber sources

# publications[].label
PRESENCE AND DISTRIBUTION OF PROTEIN-KINASE-C ISOFORMS IN RAT COLON - IMPLICATIONS FOR COLON CARCINOGENESIS

# publications[].label
Diacylglycerol and ceramide kinetics in primary cultures of activated T-lymphocytes.

# publications[].label
Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model.

# publications[].label
Modulation of mouse mammary tumor growth and linoleate enhanced metastasis by oleate.

# publications[].label
Effects of dietary n-3 fatty acids on T cell activation and T cell receptor-mediated signaling in a murine model.

# publications[].label
The non-invasive exfoliated transcriptome (exfoliome) reflects the tissue-level transcriptome in a mouse model of NSAID enteropathy.

# publications[].label
DIVERSE EFFECTS OF BUTYRATE ON PROLIFERATION IN A TRANSGENIC MOUSE COLONIC CELL-LINE

# publications[].label
Noninvasive detection of colonic biomarkers using fecal messenger RNA

# publications[].label
scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation.

# publications[].label
Bayesian Causal Structural Learning with Zero-Inflated Poisson Bayesian Networks.

# publications[].label
A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response

# publications[].label
A Unified Bayesian Framework for Bi-overlapping-Clustering Multi-omics Data via Sparse Matrix Factorization.

# publications[].label
Fish oil ameliorates the increase in colonic ras expression and activation in carcinogen-injected rats.

# publications[].label
Dietary fish oil promotes Fas-mediated apoptosis in Th1 cells

# publications[].label
Prostaglandin profile and synthetic capacity of the colon: comparison of tissue sources and subcellular fractions.

# publications[].label
Colonic cyclopurines induced by azoxymethane and irradiation are decreased by dietary fish oil

# publications[].label
In vivo regulation of colonic cell proliferation, differentiation, apoptosis, and P27Kip1 by dietary fish oil and butyrate in rats.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/PGE2 and elevation of PGE3.

# publications[].label
Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells.

# publications[].label
A chemoprotective fish oil/pectin diet regulates the expression of the bcl-2 oncogene by altering CpG island methylator phenotype (CIMP) in colon cancer

# publications[].label
Dietary modulation of rat colonic cAMP-dependent protein kinase activity.

# publications[].label
Personalized Nutrition Using Microbial Metabolite Phenotype to Stratify Participants and Non-Invasive Host Exfoliomics Reveal the Effects of Flaxseed Lignan Supplementation in a Placebo-Controlled Crossover Trial.

# publications[].label
Protein kinase C isoforms in human and rat colonic mucosa.

# publications[].label
Dietary fish oil blocks carcinogen-induced down-regulation of colonic protein kinase C isozymes.

# publications[].label
n-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes

# publications[].label
Ghrelin Alleviates Experimental Ulcerative Colitis in Old Mice and Modulates Colonocyte Metabolism via PPAR Pathway.

# publications[].label
DIETARY FISH OIL SPECIFICALLY ALTERS MURINE PERITONEAL MACROPHAGE ACTIVATION AND FUNCTION ASSESSED INVITRO

# publications[].label
Human Microbiome in Health and Disease: The Good, the Bad, and the Bugly.

# publications[].label
Fish oil is protective against colon tumorigenesis by two distinct mechanisms in a site specific manner.

# publications[].label
Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet.

# publications[].label
From crypts to enteroids: establishment and characterization of avian intestinal organoids.

# publications[].label
The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes.

# publications[].label
Dysregulation of cellular membrane homeostasis as a crucial modulator of cancer risk.

# publications[].label
Feature selection for high-dimensional integrated data

# publications[].publisher
Society for Industrial & Applied Mathematics (SIAM)

# publications[].label
SYNTHESIS OF ARACHIDONIC-ACID FROM EXOGENOUS LINOLEIC-ACID BY CULTURED MOUSE KERATINOCYTES

# publications[].label
n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon.

# publications[].label
Abstract 3443: Aryl hydrocarbon receptor and its ligands influence the formation of colonic tertiary lymphoid tissues

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary n-3 polyunsaturated fatty acids selectively promote activation-induced cell death in Th1 cells

# publications[].label
Docosahexaenoic acid selectively inhibits plasma membrane targeting of lipidated proteins.

# publications[].label
Transgenic mice enriched in omega-3 fatty acids are more susceptible to pulmonary tuberculosis: impaired resistance to tuberculosis in fat-1 mice.

# publications[].label
Alteration of colonic stem cell gene signatures during the regenerative response to injury.

# publications[].label
Higher DNA adduct levels and lower apoptosis may explain the higher cancer susceptibility in the distal colon compared to the rest of the gastrointestinal tract

# publications[].label
The role of docosahexaenoic acid in mediating mitochondrial membrane tipid oxidation and apoptosis in colonocytes

# publications[].label
In vivo formation of polyphosphoinositide isomers and association with progression of murine polycystic kidney disease.

# publications[].label
Annexin A2 modulates phospholipid membrane composition upstream of Arp2 to control angiogenic sprout initiation.

# publications[].label
n-3 polyunsaturated fatty acids suppress CD4(+) T cell proliferation by altering phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P2] organization.

# publications[].label
Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.

# publications[].label
Relationship among proliferation, p27, differentiation and apoptosis measured by colocalization in the same cell as a function of carcinogen administration

# publications[].label
High energy LET radiation as a risk modifier in colon carcinogenesis.

# publications[].label
A fish oil/pectin diet beneficially altered gene profiles during radiation-enhanced colon carcinogenesis

# publications[].label
HUMAN EPIDERMAL ENZYME PREPARATIONS CAN ELONGATE GAMMALINOLEIC ACID (18-3,N6) INTO GAMMAHOMOLINOLENIC ACID (20-3,N6)

# publications[].label
Understanding the relationship between carcinogen-induced DNA adduct levels in distal and proximal regions of the colon.

# publications[].label
Modulation of intracellular second messengers by dietary fat during colonic tumor development.

# publications[].label
The microbiome and colorectal neoplasia: environmental modifiers of dysbiosis.

# publications[].label
Dopamine is an aryl hydrocarbon receptor agonist.

# publications[].label
Alteration of in vitro murine peritoneal macrophage function by dietary enrichment with eicosapentaenoic and docosahexaenoic acids in menhaden fish oil.

# publications[].label
Abstract CN02-03: Fat-fiber combination: The missing ingredient?

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Docosahexaenoic acid. An influential membrane-altering omega-3 fatty acid

# publications[].label
Upregulation of p21Waf1/Cip1 expression in vivo by butyrate administration can be chemoprotective or chemopromotive depending on the lipid component of the diet.

# publications[].label
Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen.

# publications[].label
Docosahexaenoic acid inhibits oncogenic Ras activation and signal transduction in colonocytes.

# publications[].label
PCAN: Probabilistic correlation analysis of two non-normal data sets.

# publications[].label
Single-cell RNA Sequencing Reveals How the Aryl Hydrocarbon Receptor Shapes Cellular Differentiation Potency in the Mouse Colon.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
(n-3) Polyunsaturated fatty acids promote activation-induced cell death in murine T lymphocytes.

# publications[].label
Grapefruit and its isolated bioactive compounds act as colon cancer chemoprotectants in rats

# publications[].label
Dietary fish oil and pectin protect against oxidative DNA damage despite an increase in reactive oxygen species in rat small and large intestine epithelial cells

# publications[].label
Fish oil is a modulator of neutrophil function in chronic laminitis

# publications[].label
Effects of chemoprotective diets on crypt adult stem cells u the cells of origin of colon cancer

# publications[].label
Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1).

# publications[].label
Mechanisms by Which Pleiotropic Amphiphilic n-3 PUFA Reduce Colon Cancer Risk.

# publications[].label
ABILITY OF MONOHYDROXYEICOSATRIENOIC ACID (15-OH-20-3) TO MODULATE MACROPHAGE ARACHIDONIC-ACID METABOLISM

# publications[].label
Obesity promotes colonic stem cell expansion during cancer initiation.

# publications[].label
Differential response to dextran sodium sulfate (DSS)-induced oxidative DNA damage in rat small (SI) and large intestine (LI)

# publications[].label
Associations Between Systemic Omega-3 Fatty Acid Levels With Moderate-to-Severe Dry Eye Disease Signs and Symptoms at Baseline in the Dry Eye Assessment and Management Study.

# publications[].label
FAT, FIBER AND CARCINOGEN ALTER FATTY-ACID COMPOSITION OF FECAL DIACYLGLYCEROLS

# publications[].label
Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies.

# publications[].label
Beyond Differential Expression: Embracing Cell-to-Cell Variability in Single-Cell Gene Expression Data Analysis

# publications[].label
Detecting Multivariate Gene Interactions in RNA-Seq Data Using Optimal Bayesian Classification.

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis.

# publications[].label
A New Model to Study the Role of Arachidonic Acid in Colon Cancer Pathophysiology.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Effect of dietary n-3 fatty acids on interleukin-2 and interleukin-2 receptor alpha expression in activated murine lymphocytes.

# publications[].label
Dietary influences of evening primrose and fish oil on the skin of essential fatty acid-deficient guinea pigs.

# publications[].label
Dietary fish oil promotes colonic apoptosis and mitochondrial proton leak in oxidatively stressed mice.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
A two-stage normalization method for partially degraded mRNA microarray data.

# publications[].label
Noninvasive detection of putative biomarkers for colon cancer using fecal messenger RNA.

# publications[].label
Dietary lipid source alters fatty acid composition in mitochondrial membrane phospholipids and modulates mitochondrial function in rat colonocytes

# publications[].label
Urea synthesis in rat colonocytes is affected by fiber and carcinogen.

# publications[].label
Dietary n-3 PUFA affect TcR-mediated activation of purified murine T cells and accessory cell function in co-cultures.

# publications[].label
Dietary fish oil plus butyrate protect against colon cancer by increasing reactive oxygen species and decreasing mitochondrial membrane potential in the promotion stage of tumorigenesis

# publications[].label
Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells

# publications[].label
Identification of actively translated mRNA transcripts in a rat model of early-stage colon carcinogenesis.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary Fat-Fiber Interactions: Effect on Colonic Mediators of Cell Cytokinetics

# publications[].label
Fatty acid composition of macrophage phospholipids in mice fed fish or borage oil.

# publications[].label
Dietary fish oil reduces O6-methylguanine DNA adduct levels in rat colon in part by increasing apoptosis during tumor initiation.

# publications[].label
Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses.

# publications[].label
Dietary fish oil and DHA down-regulate antigen-activated CD4+ T-cells while promoting the formation of liquid-ordered mesodomains.

# publications[].label
n-3 Polyunsaturated Fatty Acids Suppress T-Cell Mitochondrial Translocation to the Immunological Synapse

# publications[].label
Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid.

# publications[].label
Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPARδ in inflammation-induced colon carcinogenesis.

# publications[].label
Docosahexaenoic acid alters the size and distribution of cell surface microdomains.

# publications[].label
Omega-3 fatty acids, lipid rafts, and T cell signaling.

# publications[].label
Abstract P014: A novel role of mutant APC and n3-PUFA in reshaping cholesterol-dependent Wnt pathway-associated proteolipid nanocluster organization and signaling in colorectal cancer

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Genome-wide analysis of the rat colon reveals proximal-distal differences in histone modifications and proto-oncogene expression.

# publications[].label
Chemopreventive Effects of Omega-3 Fatty Acids

# publications[].label
SUPRESSION OF INVITRO ACTIVATION OF TUMORICIDAL FUNCTION IN PERITONEAL-MACROPHAGES FROM FISH OIL FED MICE

# publications[].label
Combined effect of radiation and a chemical carcinogen on the formation of aberrant crypt foci in rat colon.

# publications[].label
Fate and distribution of orally-ingested CeO2-nanoparticles based on a mouse model: Implication for human health

# publications[].label
Dietary curcumin and limonin suppress murine CD4(+) T-cell activation

# publications[].label
Interactive effects of fatty acid and butyrate-induced mitochondrial Ca loading and apoptosis in colonocytes.

# publications[].label
Dietary fish oil and pectin protect against oxidative DNA damage in rat intestinal epithelial cells due to heightened apoptosis induced by reactive oxygen species

# publications[].label
Bioactive dietary long-chain fatty acids: emerging mechanisms of action.

# publications[].label
Assessment of histone tail modifications and transcriptional profiling during colon cancer progression reveals a global decrease in H3K4me3 activity.

# publications[].label
Chemoprotective epigenetic mechanisms in a colorectal cancer model: Modulation by n-3 PUFA in combination with fermentable fiber.

# publications[].label
Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation.

# publications[].label
Increased phospholipid mass with decreased arachidonoyl molecular species is associated with decreased eicosanoid synthesis and increased tumor necrosis factor synthesis by thioglycollate-elicited rat peritoneal macrophages.

# publications[].label
Shift work cycle-induced alterations of circadian rhythms potentiate the effects of high-fat diet on inflammation and metabolism.

# publications[].label
Host-microbe interactions in the neonatal intestine: role of human milk oligosaccharides.

# publications[].label
Pro-oxidant environment of the colon compared to the small intestine may contribute to greater cancer susceptibility.

# publications[].label
Structure-activity relationships among mono- and dihydroxy flavones as aryl hydrocarbon receptor (AhR) agonists or antagonists in CACO2 cells.

# publications[].label
Response from Chapkin to Letter from Boucher

# publications[].label
Inhibition of growth and linoleate-enhanced metastasis of a transplantable mouse mammary tumor by indomethacin.

# publications[].label
Diet and carcinogen alter the fecal microbial populations of rats.

# publications[].label
Dietary fat and fiber modulate colonic cell proliferation in an interactive site-specific manner.

# publications[].label
Lipidomic and biophysical homeostasis of mammalian membranes in response to dietary lipids is essential for cellular fitness

# publications[].label
Dietary fish oil inhibits antigen-specific murine Th1 cell development by suppression of clonal expansion.

# publications[].label
Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes.

# publications[].label
Cell cycle related inhibition of mouse vascular smooth muscle cell proliferation by prostaglandin E1: relationship between prostaglandin E1 and intracellular cAMP levels.

# publications[].label
Dietary(n-3) polyunsaturated fatty acids modulate murine Th1/Th2 balance toward the Th2 pole by suppression of Th1 development

# publications[].label
Comparing automatic and manual image processing in FLARE assay analysis for colon carcinogenesis.

# publications[].label
scTenifoldKnk: An Efficient Virtual Knockout Tool for Gene Function Predictions via Single-Cell Gene Regulatory Network Perturbation

# publications[].label
Dietary fish oil down-regulates pro-inflammatory gene expression in colonocytes

# publications[].label
Dietary gamma-linolenic acid enhances mouse macrophage-derived prostaglandin E1 which inhibits vascular smooth muscle cell proliferation.

# publications[].label
Exfoliated epithelial cell transcriptome reflects both small and large intestinal cell signatures in piglets.

# publications[].label
Extinction scenarios in evolutionary processes: A Multinomial  Wright-Fisher approach

# publications[].label
Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells.

# publications[].label
Effect of vitamin E supplementation on serum and high-density lipoprotein-cholesterol in renal patients on maintenance hemodialysis.

# publications[].label
n-3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease.

# publications[].label
Dietary fish oil reduces oxidative DNA damage in rat colonocytes.

# publications[].label
Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells.

# publications[].label
Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.

# publications[].label
Dietary fish oil enhances targeted apoptosis response to dextran sodium sulfate (DSS)-induced oxidative DNA damage in the top part of the colonic crypt

# publications[].label
Bayesian biclustering for microbial metagenomic sequencing data via multinomial matrix factorization.

# publications[].label
n-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes.

# publications[].label
Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPAR-FGF21 Axis.

# publications[].label
Distinct Adipose Depots from Mice Differentially Respond to a High-Fat, High-Salt Diet.

# publications[].label
Fish oil depresses the carcinogen-induced expression of COX-2 in rat colonic mucosa.

# publications[].label
Dietary linoleic acid and butyrate suppress apoptosis by enhancing Bcl-2 expression

# publications[].label
The combination of dietary fish oil and butyrate decreases high-multiplicity aberrant crypt foci in experimentally induced colon cancer

# publications[].label
Dietary fish oil alters the accumulation of antigen-specific CD4(+) T cells in the lymph nodes of recipient mice following adoptive transfer and immunization

# publications[].label
Role of the Aryl Hydrocarbon Receptor (AhR) in Mediating the Effects of Coffee in the Colon.

# publications[].label
Dietary fish oil reduces colon cancer risk

# publications[].label
Dietary n-3 polyunsaturated fatty acids modulate purified T cell subset activation

# publications[].label
n-3 Fatty acids uniquely affect anti-microbial resistance and immune cell plasma membrane organization.

# publications[].label
Carcinogen and dietary lipid regulate ras expression and localization in rat colon without affecting farnesylation kinetics.

# publications[].label
Plasma membrane lipid therapy: disruption of oncogenic Ras spatiotemporal organization by membrane-targeted dietary bioactives (MTDB)

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Diet and disease alter phosphoinositide composition and metabolism in murine polycystic kidneys.

# publications[].label
Chain elongation of eicosapentaenoic acid in the macrophage.

# publications[].label
DHA decreases plasma membrane localization of Ras in colonic epithelial cells

# publications[].label
Loss of aryl hydrocarbon receptor suppresses the response of colonic epithelial cells to IL22 signaling by upregulating SOCS3.

# publications[].label
ALTERATIONS OF EPIDERMAL LIPID-METABOLISM IN ESSENTIAL FATTY-ACID DEFICIENT GUINEA-PIGS

# publications[].label
Regulatory activity of polyunsaturated fatty acids in T-cell signaling.

# publications[].label
Fecal microbiota composition of breast-fed infants is correlated with human milk oligosaccharides consumed.

# publications[].label
Predictive value of proliferation, differentiation and apoptosis as intermediate markers for colon tumorigenesis.

# publications[].label
Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice.

# publications[].label
Targeting plasma membrane cholesterol as a novel anticancer therapy.

# publications[].label
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action.

# publications[].label
Effects of high-fat diet and intestinal aryl hydrocarbon receptor deletion on colon carcinogenesis.

# publications[].label
Chemoprotective nutrients modulate intracellular calcium compartmentalization and store-operated channel entry to induce colonocyte apoptosis

# publications[].label
A combination of omega-3 fatty acids and a butyrate-producing fiber mitigates colon cancer development

# publications[].label
EFFECT OF DIETS CONTAINING N-3 FATTY-ACIDS ON THE PRODUCTION OF 5 SERIES PEPTIDO-LEUKOTRIENES BY PERITONEAL-MACROPHAGES

# publications[].label
Dietary n-3 polyunsaturated fatty acids suppress splenic CD4(+) T cell function in interleukin (IL)-10(-/-) mice.

# publications[].label
Tissue-specific attenuation of endogenous DNA I-compounds in rats by carcinogen azoxymethane: possible role of dietary fish oil in colon cancer prevention.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
PREDICTIVE VALUE OF PROLIFERATION, DIFFERENTIATION AND APOPTOSIS AS INTERMEDIATE MARKERS FOR COLON TUMORIGENESIS

# publications[].label
3,3'-Diindolylmethane and 1,4-dihydroxy-2-naphthoic acid prevent chronic mild stress induced depressive-like behaviors in female mice.

# publications[].label
Alteration of glycerolipid and sphingolipid-derived second messenger kinetics in ras transformed 3T3 cells.

# publications[].label
Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial calcium accumulation

# publications[].label
Dietary n3 PUFA affect TcRmediated activation of purified murine T cells and accessory cell function in cocultures

# publications[].label
Aryl Hydrocarbon Receptor (AhR) Signaling in Colonic Cells and Tumors.

# publications[].label
Inability of murine peritoneal macrophages to convert linoleic acid into arachidonic acid. Evidence of chain elongation.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux.

# publications[].label
Dietary n-3 Polyunsaturated Fatty Acids Modulate T-Lymphocyte Activation

# publications[].label
Noninvasive stool-based detection of infant gastrointestinal development using gene expression profiles from exfoliated epithelial cells.

# publications[].label
Remodelling of primary human CD4+ T cell plasma membrane order by n-3 PUFA.

# publications[].label
Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs).

# publications[].label
A fish oil/pectin diet suppresses radiation-enhanced colon carcinogenesis via down-regulation of the beta-catenin signaling pathway

# publications[].label
Differential response to DNA damage may explain different cancer susceptibility between small and large intestine.

# publications[].label
Assessing the Multivariate Relationship between the Human Infant Intestinal Exfoliated Cell Transcriptome (Exfoliome) and Microbiome in Response to Diet.

# publications[].label
n-3 Polyunsaturated fatty acids exert immunomodulatory effects on lymphocytes by targeting plasma membrane molecular organization.

# publications[].label
Influence of dietary lipid and butyrate on the coordination of proliferation, p27, differentiation and apoptosis in the same cell during the initiation stage of colon carcinogenesis

# publications[].label
Dietary fiber differentially alters cellular fatty acid-binding protein expression in exfoliated colonocytes during tumor development.

# publications[].label
Select dietary fats and fibers block carcinogen-induced down-regulation down-regulation of colonic protein kinase C.

# publications[].label
Emerging role of chemoprotective agents in the dynamic shaping of plasma membrane organization.

# publications[].label
Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
Dietary fat and fiber alter rat colonic protein kinase C isozyme expression.

# publications[].label
Luminal butyrate concentration is positively associated with colonocyte differentiation and apoptosis and negatively associated with proliferation.

# publications[].label
Fish oil and pectin may suppress colon carcinogenesis via inhibition of the MAPK and TGF beta pathways

# publications[].label
Alteration of EGFR spatiotemporal dynamics suppresses signal transduction.

# publications[].label
Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity.

# publications[].label
Docosahexaenoic acid-induced inhibition of plasma membrane targeting is reversible and selective to lipidated cytosolic proteins

# publications[].label
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness.

# publications[].label
Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes.

# publications[].label
Dietary lipids and curcumin interact to affect gene expression in a mouse model of DSS induced chronic colitis

# publications[].label
Phospholipid molecular species composition of mouse liver nuclei. Influence of dietary n-3 fatty acid ethyl esters.

# publications[].label
Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic -catenin.

# publications[].label
Colonocyte DNA damage differs with diet but not age

# publications[].label
Dietary fish oil reduces N7-deoxymethylguanine adducts by enhancing apoptosis at the initiation stage of carcinogenesis in the small (SI) and large intestine (LI)

# publications[].label
Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis.

# publications[].label
scTenifoldKnk: an efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation

# publications[].label
The Interaction between Dietary Fiber and Fat and Risk of Colorectal Cancer in the Women's Health Initiative.

# publications[].label
Diet-Host-Microbiota Interactions Shape Aryl Hydrocarbon Receptor Ligand Production to Modulate Intestinal Homeostasis.

# publications[].label
n-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon.

# publications[].label
EFFECT OF DIETARY-FIBERS AND FATS ON RAT COLON PROTEIN-KINASE-C ACTIVITY - CORRELATION TO CELL-PROLIFERATION

# publications[].label
ALTERED PHOSPHOLIPID AD FATTY-ACID COMPOSITIONS IN SERUM AND HIGH-DENSITY LIPOPROTEINS OF RENAL PATIENTS ON MAINTENANCE HEMODIALYSIS

# publications[].label
Immunomodulatory effects of (n-3) fatty acids: Putative link to inflammation and colon cancer

# publications[].label
Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.

# publications[].label
Dietary manipulation of macrophage phospholipid classes: selective increase of dihomogammalinolenic acid.

# publications[].label
DIETARY FISH OIL MODULATION OF INVIVO PERITONEAL MACROPHAGE LEUKOTRIENE PRODUCTION AND PHAGOCYTOSIS

# publications[].label
Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.

# publications[].label
Butter fat may protect against colon carcinogenesis through decreased cell proliferation mediated by changes in prostaglandin production.

# publications[].label
Sex-dependent differences in the stress mitigating and antidepressant effects of selective aryl hydrocarbon receptor modulators.

# publications[].label
Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts.

# publications[].label
Bayesian biclustering for microbial metagenomic sequencing data via  multinomial matrix factorization

# publications[].label
UTILIZATION OF BUTYRATE BY COLONOCYTES IS ALTERED DURING THE TUMORIGENIC PROCESS

# publications[].label
Rapid competitive PCR determination of relative gene expression in limiting tissue samples.

# publications[].label
Non-invasive stool-based detection of newborn infant gastrointestinal development using gene expression profiles derived from exfoliated epithelial cells

# publications[].label
Omega-3 Fatty Acids in Cancer Prevention and Control: A Membrane Perspective

# publications[].label
Dietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice.

# publications[].label
n-3 polyunsaturated fatty acids suppress mitochondrial translocation to the immunologic synapse and modulate calcium signaling in T cells.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Mass and fatty acid composition of the 3-phosphorylated phosphatidylinositol bisphosphate isomer in stimulated human platelets.

# publications[].label
A macrophage-smooth muscle cell co-culture model: applications in the study of atherogenesis.

# publications[].label
Loss of Aryl Hydrocarbon Receptor Promotes Colon Tumorigenesis in ApcS580/+; KrasG12D/+ Mice.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
n-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4 T cells.

# publications[].label
A novel role for n-3 polyunsaturated fatty acids in inhibition of EGFR signal transduction

# publications[].label
Biologic significance of polyunsaturated fatty acids in the skin.

# publications[].label
Selective aryl hydrocarbon receptor modulators can act as antidepressants in obese female mice.

# publications[].label
DIETARY REPLACEMENT WITH FISH OIL DID NOT REVERSE EPIDERMAL HYPERPROLIFERATION OF EFA-DEFICIENT GUINEA-PIG SKIN

# publications[].label
Dietary n-3 PUFA affect TcR-mediated activation of purified murine T cells and accessory cell function in co-cultures (vol 130, pg 12, 2002)

# publications[].label
Quercetin decreases the number of high multiplicity aberrant crypt foci (ACF) but not the total number of ACF in rat colon

# publications[].label
A chemoprotective fish oil/pectin diet enhances apoptosis via Bcl-2 promoter methylation in rat azoxymethane-induced carcinomas.

# publications[].label
Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro.

# publications[].label
Effect of docosahexaenoic acid on ras post-translational processing and localization in a transgenic mouse colonic cell line.

# publications[].label
Mitochondria-targeted disruptors and inhibitors of cytochrome c/cardiolipin peroxidase complexes: a new strategy in anti-apoptotic drug discovery.

# publications[].label
Murine Colonic Organoid Culture System and Downstream Assay Applications.

# publications[].label
0447 Microbial modulation of the neonatal immune system: Lessons from infants and piglets

# publications[].label
DIETARY MODULATION OF BIOMARKERS OF COLON CARCINOGENESIS - INTERACTIVE EFFECT OF DIFFERENT TYPES OF FIBER AND FAT

# publications[].label
Diet therapy abates mutant APC and KRas effects by reshaping plasma membrane cholesterol nanodomains.

# publications[].label
Dietary prevention of colon cancer induced by combined effect of carcinogen and radiation

# publications[].label
Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis (vol 139, pg 101, 2009)

# publications[].label
Dietary n-3 PUFA affect TcR-mediated activation of purified murine T cells and accessory cell function in co-cultures

# publications[].label
Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells

# publications[].label
Dietary fat and fiber modulate the effect of carcinogen on colonic protein kinase C lambda expression in rats.

# publications[].label
Role of Inflammatory Signaling in the Differential Effects of Saturated and Poly-unsaturated Fatty Acids on Peripheral Circadian Clocks.

# publications[].label
n-3 PUFA and membrane microdomains: a new frontier in bioactive lipid research.

# publications[].label
Comparison of the chemoprotection conferred by grapefruit and isolated bioactive compounds against colon cancer

# publications[].label
Rapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk.

# publications[].label
Fish oil enhances targeted apoptosis during colon tumor initiation in part by downregulating Bcl-2.

# publications[].label
Dietary polyunsaturated fatty acids modulate resistance to Mycobacterium tuberculosis in guinea pigs.

# publications[].label
Apigenin and naringenin suppress high multiplicity aberrant crypt foci formation and cell proliferation in rat colon

# publications[].label
DIETARY N-3 FATTY-ACID DOWN-REGULATION OF LYMPHOCYTE-PROLIFERATION IS PRECEDED BY INCREASES IN CERAMIDE MASS

# publications[].label
Dietary fat, fiber, and carcinogen alter fecal diacylglycerol composition and mass.

# publications[].label
Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids.

# publications[].label
Non-invasive detection of fecal protein kinase C betaII and zeta messenger RNA: putative biomarkers for colon cancer.

# publications[].label
Recent advances in the field of nutritional immunology.

# publications[].label
GHS-R suppression in adipose tissues protects against obesity and insulin resistance by regulating adipose angiogenesis and fibrosis.

# publications[].label
Dietary n-3 polyunsaturated fatty acids (PUFA) promote activation-induced cell death (AICD) in Th1-polarized murine T cells

# publications[].label
Single-cell transcriptomics reveals that human milk feeding shapes neonatal immune cell interleukin signaling pathways in a nonrandomized clinical trial.

# publications[].label
Non-invasive evaluation of the equine gastrointestinal mucosal transcriptome.

# publications[].label
Dietary fibers and fats alter rat colon protein kinase C activity: correlation to cell proliferation.

# publications[].label
Effect of a Flaxseed Lignan Intervention on Circulating Bile Acids in a Placebo-Controlled Randomized, Crossover Trial.

# publications[].label
Dietary lipid source alters quercetin effects on antioxidant enzyme/phase I and II gene expression in rat colon

# publications[].label
Modulation of atherogenesis by dietary gamma-linolenic acid.

# publications[].label
Mechanistic insights into the role of microRNAs in cancer: influence of nutrient crosstalk.

# publications[].label
Utilization of dihomo-gamma-linolenic acid (8,11,14-eicosatrienoic acid) by murine peritoneal macrophages.

# publications[].label
Importance of Dietary -Linolenic Acid in Human Health and Nutrition

# publications[].label
Noninvasive molecular fingerprinting of host-microbiome interactions in neonates.

# publications[].label
Aberrant crypt foci and semiparametric modeling of correlated binary data.

# publications[].label
Dietary n-3 PUFA alter colonocyte mitochondrial membrane composition and function.

# publications[].label
Dietary fat and fiber modulate the colonic redox environment during the initiation stage of radiation-enhanced colon carcinogenesis in rats

# publications[].label
THE MITOGENIC EFFECT OF MACROPHAGES UPON VASCULAR SMOOTH-MUSCLE CELLS IS DOWN-REGULATED BY DIETARY GAMMA-LINOLENIC ACID - ROLE OF CYCLOOXYGENASE DERIVED METABOLITES

# publications[].label
Dietary fat and fiber alter rat colonic mucosal lipid mediators and cell proliferation.

# publications[].label
Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling.

# publications[].label
fat-1 transgene expression prevents cell culture-induced loss of membrane n-3 fatty acids in activated CD4+ T-cells.

# publications[].label
EFFECTS OF PURIFIED DIETARY N-3 ETHYL-ESTERS ON MURINE LYMPHOCYTE-T FUNCTION

# publications[].label
Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis.

# publications[].label
Abstract 236: Nuclear receptor 4A1 ligands target T-cell exhaustion in colorectal cancer

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Interactions of phospholipase D and cytochrome P450 protein stability.

# publications[].label
Nuclear receptor 4A1 ligands target T-cell exhaustion in colorectal cancer

# publications[].label
PHOSPHOLIPID SOURCES OF METABOLICALLY ELONGATED GAMMA-LINOLENIC ACID - CONVERSION TO PROSTAGLANDIN-E(1) IN STIMULATED MOUSE MACROPHAGES

# publications[].label
Quercetin Suppresses Early Colon Carcinogenesis Partly through Inhibition of Inflammatory Mediators.

# publications[].publisher
International Society for Horticultural Science (ISHS)

# publications[].label
Fish oil decreases oxidative DNA damage by enhancing apoptosis in rat colon.

# publications[].label
Composition of mouse peritoneal macrophage phospholipid molecular species.

# publications[].label
Bayesian Classification of Microbial Communities Based on 16S rRNA Metagenomic Data

# publications[].label
A diet of fish oil and pectin reduces colonic antioxidant enzymes creating an environment permissive for ROS-induced apoptosis

# publications[].label
Docosahexaenoic acid alters the spatio-temporal segregation and activation of EGF receptor

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells.

# publications[].label
Dietary n-3 polyunsaturated fatty acids modulate purified murine T-cell subset activation.

# publications[].label
Reduced colitis-associated colon cancer in Fat-1 (n-3 fatty acid desaturase) transgenic mice.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in Th1-polarized murine CD4+ T-cells.

# publications[].label
Modulation of protein kinase C-related signal transduction by 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibits cell cycle dependence.

# publications[].label
Dietary fish oil suppresses clonal expansion during antigen-stimulated marine Th1 differentiation

# publications[].label
DETERMINATION OF DIACYLGLYCEROL MOLECULAR-SPECIES IN RAS-TRANSFORMED 3T3 CELLS

# publications[].label
Parametric and nonparametric methods for understanding the relationship between carcinogen-induced DNA adduct levels in distal and proximal regions of the colon

# publications[].label
Interference with protein kinase C-related signal transduction in vascular smooth muscle cells by benzo[a]pyrene.

# publications[].label
Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids.

# publications[].label
Protocol of the Snuggle Bug/Acurrucadito Study: a longitudinal study investigating the influences of sleep-wake patterns and gut microbiome development in infancy on rapid weight gain, an early risk factor for obesity.

# publications[].label
Non-invasive analysis of intestinal development in preterm and term infants using RNA-Sequencing.

# publications[].label
Chemotherapeutic Properties of n-3 Polyunsaturated Fatty Acids - Old Concepts and New Insights.

# publications[].label
Quercetin does not significantly affect the protection of a fish oil diet in early colon careinogenesis

# publications[].label
Down-regulation of T-cell interleukin-2 production by dietary N-3 fatty acids is independent of interleukin-2 gene transcription

# publications[].label
Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer.

# publications[].label
Chapkin studies "signaling cascades" in colon

# publications[].label
Diet and Gut Microbes Act Coordinately to Enhance Programmed Cell Death and Reduce Colorectal Cancer Risk.

# publications[].label
Membrane therapy using DHA suppresses epidermal growth factor receptor signaling by disrupting nanocluster formation.

# publications[].label
Imaging inflammation in mouse colon using a rapid stage-scanning confocal fluorescence microscope.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Dietary n-3 polyunsaturated fatty acids (PUFA) decrease obesity-associated Th17 cell-mediated inflammation during colitis.

# publications[].label
Anatomical site-specific response to DNA damage is related to later tumor development in the rat azoxymethane colon carcinogenesis model.

# publications[].label
SYNTHESIS OF ARACHIDONIC-ACID FROM EXOGENOUS LINOLEIC-ACID BY CULTURED MOUSE KERATINOCYTES

# publications[].label
Relationship between DNA adduct levels, repair enzyme, and apoptosis as a function of DNA methylation by azoxymethane.

# publications[].label
n-3 polyunsaturated fatty acids--physiological relevance of dose.

# publications[].label
Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: Effect of a chemoprotective diet

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary amphiphilic polyphenols modulate the biophysical properties of plasma membrane organization and membrane-dependent macropinocytosis

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Colon cancer, fatty acids and anti-inflammatory compounds.

# publications[].label
Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats.

# publications[].label
Conversion of linoleic acid into arachidonic acid by cultured murine and human keratinocytes.

# publications[].label
Protein kinase C zeta isoform is critical for mitogenic signal transduction.

# publications[].label
194; INGESTION OF A MENHADEN OIL DIET ALTERS ENDOTOXIN-SENSITIVE ARACHIDONIC ACID POOLS

# publications[].label
PROSTAGLANDIN PROFILE AND SYNTHETIC CAPACITY OF THE COLON - COMPARISON OF TISSUE SOURCES AND SUBCELLULAR-FRACTIONS

# publications[].label
Diet induced rat colonic reactive oxygen species production is age dependent

# publications[].label
AdipoRon Attenuates Wnt Signaling by Reducing Cholesterol-Dependent Plasma Membrane Rigidity.

# publications[].label
Dietary phytate reduces proliferation and increases apoptosis in rat colonocytes

# publications[].label
Growth-related signaling in vascular smooth muscle cells is deregulated by TCDD during the G0/G1 transition.

# publications[].label
Comprehensive site-specific whole genome profiling of stromal and epithelial colonic gene signatures in human sigmoid colon and rectal tissue.

# publications[].label
n-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft formation.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Dietary fish oil may decrease colonic cell proliferation by upregulating p27Kip1 level in actively proliferating cells

# publications[].label
Docosahexaenoic acid and butyrate synergistically enhance mitochondrial membrane lipid oxidation and the dissipation of membrane potential

# publications[].label
Assessment of Plasma Membrane Fatty Acid Composition and Fluidity Using Imaging Flow Cytometry.

# publications[].label
5-series peptido-leukotriene synthesis in mouse peritoneal macrophages: modulation by dietary n-3 fatty acids.

# publications[].label
Intestinal epithelium aryl hydrocarbon receptor is involved in stress sensitivity and maintaining depressive symptoms.

# publications[].label
Th17 cell accumulation is decreased during chronic experimental colitis by (n-3) PUFA in Fat-1 mice.

# publications[].label
Dietary fish oil, compared to corn oil, decreased oxidative DNA damage at the base and middle region of the colonic crypt in dextran sodium sulfate (DSS)-treated rats.

# publications[].label
Dietary fat and fiber differentially alter intracellular second messengers during tumor development in rat colon.

# publications[].label
Biography of Joanne R Lupton (1944-2020).

# publications[].label
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.

# publications[].publisher
American Association for Cancer Research (AACR)

# researcherOn[].label
Role of Aryl Hydrocarbon Receptor in Microbiota-Colon Stem Cell Interactions

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
Molecular Basis for Dietary Chemoprevention

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Chemoprotective Effects of Natural Products on Colonic Adult Stem Cells

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Food systems, health, and well-being: understanding complex relationships and dynamics of change

# researcherOn[].awardedBy.label
National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Ghrelin deficiency predisposes mice to aging-associated inflammation through compromised gut function and microbiota dysbiosis

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Chemoprotective Effects of EPA and DHA on Colonic Adult Stem Cells

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Nutrition, Biostatistics and Bioinformatics Training Grant

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Targeting plasma membrane spatial dynamics to suppress aberrant Wnt signaling

# researcherOn[].awardedBy.label
National Cancer Institute - (Rockville, Maryland, United States)

# researcherOn[].label
Diet-dependent regulation of DCIS progression

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Diet induced modifications of microbiota metabolites in colon tumorigenesis

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Targeting Plasma Membrane Spatial Dynamics to Suppress Obesity-Induced Colon Cancer

# researcherOn[].awardedBy.label
Cancer Prevention and Research Institute of Texas - (Austin, Texas, United States)

# researcherOn[].label
The Effects of Endogenous and Dietary Estrogen On Colonic Stem Cells

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Protective role of adenosine 2A receptor in NAFLD

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Metabolic regulation of adipocyte-macrophage crosstalk in obesity

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Dietary Flavonoids-Microbiota-Ah Receptor Interactions in the Gut

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Center for Complementary and Alternative Medicine

# researcherOn[].label
Radiation-induced Apoptosis Avoidance and Colon Tumorigenesis: Epigenetic Regulation in Adult Stem Cells

# researcherOn[].awardedBy.label
Johnson Space Center - (Houston, Texas, United States)

# streetAddress
Texas A&M University; Nutrition & Food Science; 2253 TAMU

# organizations[]
College of Agriculture and Life Sciences

# schools[]
College of Agriculture and Life Sciences

# inTheNews[].label
Texas A&M receives $7.1 million in grants for cancer research

# inTheNews[].label
Researchers target cell membrane for cancer research

# etdChairOf[].label
Ly, Lan H. (2004-12). Immunosuppressive dietary n-3 polyunsaturated fatty acids differentially modulate costimulatory regulation of murine CD4+ T-cell function. Doctoral Dissertation.

# etdChairOf[].label
Zhang, Ping (2005-08). The selective effect of dietary n-3 polyunsaturated fatty acids on murine Th1 and Th2 cell development. Doctoral Dissertation.

# etdChairOf[].label
Turk, Harmony 1985- (2012-12). The Role of Docosahexaenoic Acid in Regulation of Epidermal Growth Factor Receptor Activation and Function. Doctoral Dissertation.

# etdChairOf[].label
Allen, Marilyn Jean (2014-08). N-3 Polyunsaturated Fatty Acids Reduce Th17 Differentiation by Decreasing Responsiveness to Interleukin-6 in Mice. Master's Thesis.

# etdChairOf[].label
Seo, Jeongmin (2004-12). Docosahexaenoic acid differentially modulates plasma membrane targeting and subcellular localization of lipidated proteins in colonocytes. Doctoral Dissertation.

# etdChairOf[].label
Switzer, Kirsten Collette (2004-08). The effect of dietary n-3 polyunsaturated fatty acids on T cell subset activation-induced cell death. Doctoral Dissertation.

# etdChairOf[].label
Triff, Karen (2016-05). Assessment of Histone Tail Modifications and Transcriptional Profiling during Colon Cancer Progression: Effect of Chemoprotective Natural Compounds. Doctoral Dissertation.

# etdChairOf[].label
Kolar, Satya Sree N. (2007-08). Docosahexaenoic acid and butyrate synergistically modulate intracellular calcium compartmentalization to induce colonocyte apoptosis. Doctoral Dissertation.

# etdChairOf[].label
Shah, Manasvi Shailesh 1984- (2012-12). Modulation of Intestinal Micrornas by a Chemoprotective Diet. Doctoral Dissertation.

# etdChairOf[].label
Ng, Yee Voon (2004-08). The role of docosahexaenoic acid in mediating mitochondrial membrane lipid peroxidation and apoptosis in colonocytes.. Master's Thesis.

# etdChairOf[].label
Hou, Tim Yu-Tien (2014-12). n-3 Polyunsaturated Fatty Acids Alter Mouse CD4+ T Cell Activation by Modifying the Lipid Bilayer Properties. Doctoral Dissertation.

# etdChairOf[].label
Kim, Eun Joo (2017-12). Spatiotemporal Effects of Dietary Bioactives on Lgr5+ Stem Cells during Colon Tumorigenesis. Doctoral Dissertation.

# etdChairOf[].label
Kim, Wooki (2008-12). Molecular mechanisms of immunosuppressive effects of dietary n-3 pufa, curcumin and limonin on murine cd4+ t cells. Doctoral Dissertation.

# etdChairOf[].label
Jia, Qian 1980- (2011-08). n-3 PUFA and Curcumin Modulate the Resolution of Murine Intestinal Inflammtion. Doctoral Dissertation.

# etdChairOf[].label
Yog, Rajeshwari (2010-12). n-3 Polyunsaturated Fatty Acids Suppress Mitochondrial Translocation to the Immunological Synapse and Modulate Calcium Signaling in T Cells. Master's Thesis.

# etdChairOf[].label
Fuentes, Natividad R (2017-12). Plasma Membrane Lipid Therapy: Disruption of Oncogenic Ras Driven Phenotypes by Membrane Targeted Dietary Bioactives (Mtdb). Doctoral Dissertation.