# overview
Product recovery and purification; assays in support of product quality; enzyme assays; immunological assays, HPLC. Transgenic plant extraction and protein recovery; biomass conversion. Biopharmaceutical and vaccine manufacturing and quality control testing. cGMP and GLP compliance.

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Downstream Processing Of Antibodies Produced

# keywords[]
Purification Of Antibodies From Transgenic Plants

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# educationAndTraining[].organization.label
Colorado State University - (Fort Collins, Colorado, United States)

# educationAndTraining[].organization.label
Northeastern University - (Boston, Massachusetts, United States)

# publications[].label
Industrial Proteins Produced from Transgenic Plants

# publications[].label
BIOT 211-Evaluation and removal of key plant-derived impurities during downstream process development

# publications[].label
Transgenic plants: Commercial opportunities and challenges for pharmaceutical and industrial products

# publications[].label
Unprecedented enhancement of recombinant protein production in sugarcane culms using a combinatorial promoter stacking system.

# publications[].label
Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes).

# publications[].label
Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Proteases and lymphocyte cytotoxic killing mechanisms.

# publications[].label
TrypZean: An Animal-Free Alternative to Bovine Trypsin

# publications[].label
Plant molecular farming: systems and products.

# publications[].label
Monoclonal antibody manufacturing in transgenic plants--myths and realities.

# publications[].label
Improved recovery of active recombinant laccase from maize seed.

# publications[].label
Delivery of subunit vaccines in maize seed.

# publications[].label
Maize (Zea mays)-derived bovine trypsin: characterization of the first large-scale, commercial protein product from transgenic plants.

# publications[].label
2000 Congress Symposium on Molecular Farming: Development of an edible subunit vaccine in corn against enterotoxigenic strains of Escherichia coli

# publications[].label
P-4 and RNKP-7, new granzyme-like serine proteases expressed in activated rat lymphocytes.

# publications[].publisher
The American Association of Immunologists

# publications[].label
BIOT 267-Pretreatment of plant extracts containing MAb may be desirable

# publications[].label
Method of Increasing Recovery of Heterologous Active Enzymes Produced in Plants

# publications[].label
Evaluation of monoclonal antibody and phenolic extraction from transgenic Lemna for purification process development.

# publications[].label
Purification of Monoclonal Antibodies From Plants

# publications[].label
Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Downstream processing of recombinant proteins from transgenic feedstock.

# publications[].label
Prospects for plant-made bioindustrial and biopharmaceutical products

# publications[].label
Production of Aprotinin in Transgenic Maize Seeds for the Pharmaceutical and Cell Culture Markets

# publications[].label
Purification of Antibodies From Transgenic Plants

# publications[].label
Prodigene Produces Bovine Trypsin in Corn

# publications[].label
Evaluation of processing options for transgenic sugarcane tissue expressing bovine lysozyme

# publications[].label
Flow cytometric analysis of T-independent antigen binding to dinitrophenyl-specific cells.

# publications[].publisher
The American Association of Immunologists

# publications[].label
A scalable system for generation of mesenchymal stem cells derived from induced pluripotent cells employing bioreactors and degradable microcarriers.

# publications[].label
Fluorescent derivatives of diphenyl [1-(N-peptidylamino)alkyl]phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases.

# publications[].label
Processing of permeabilized Chlorella vulgaris biomass into lutein and protein-rich products

# publications[].label
Membrane changes in lipopolysaccharide-stimulated murine B lymphocytes associated with cell activation.

# publications[].label
Phenolics removal from transgenic Lemna minor extracts expressing mAb and impact on mAb production cost.

# publications[].label
Enhanced Expression Levels of Cellulase Enzymes Using Multiple Transcription Units

# publications[].label
Commercial production of trypsin by transgenic maize

# publications[].label
Expression of the sweet protein brazzein in maize for production of a new commercial sweetener.

# publications[].label
Purification and characterization of recombinant Cel7A from maize seed.

# publications[].label
Purification of Antibodies From Transgenic Plants

# publications[].label
The Impact of Six Critical Impurities on Recombinant Protein Recovery and Purification from Plant Hosts

# publications[].label
Purification of recombinant aprotinin produced in transgenic corn seed: Separation from CTI utilizing ion-exchange chromatography

# publications[].label
Recovery of bovine lysozyme from transgenic sugarcane stalks: extraction, membrane filtration, and purification.

# publications[].label
Removal of phenolic compounds by adsorption on polymeric resins before protein purification

# publications[].label
Synthesis and kinetic studies of diphenyl 1-(N-peptidylamino)alkanephosphonate esters and their biotinylated derivatives as inhibitors of serine proteases and probes for lymphocyte granzymes.

# researcherOn[].label
Developing a Highly Capable Biomanufacturing Technical Workforce in South Texas

# researcherOn[].awardedBy.label
Directorate for Education & Human Resources - (Arlington, Virginia, United States)

# streetAddress
Texas A & M University; Chemical Engineering; 3122 TAMU

# inTheNews[].label
Researchers developing COVID-19 spike proteins to identify antibodies, prevent infection