# positions[].organizations[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# keywords[]
Nlr Family, Pyrin Domain-containing 3 Protein

# keywords[]
Hypoxia-Inducible Factor 1, Alpha Subunit

# keywords[]
NLR Family, Pyrin Domain-Containing 3 Protein

# keywords[]
Nod-, Lrr- And Pyrin Domain-containing Protein 3 (nlrp3) Inflammasomes

# keywords[]
Janus Kinase/signal Transducers And Activators Of The Transcription (jak/stat) Signaling

# keywords[]
NLR Family, Pyrin Domain-Containing 3 Protein

# keywords[]
Human Mesenchymal Stem Cell-derived Extracellular Vesicles

# keywords[]
Human Induced Pluripotent Stem (hips) Cells

# keywords[]
Nlr Family, Pyrin Domain-containing 3 Protein

# keywords[]
Nlr Family, Pyrin Domain-containing 3 Protein

# keywords[]
Human Induced Pluripotent Stem Cell‐derived Neural Stem Cells

# keywords[]
Cyclic Amp Response-element Binding Protein

# educationAndTraining[].organization.label
St Aloysius College - (Mangalore, India)

# educationAndTraining[].organization.label
Nitte University - (Mangalore, Karnataka, India)

# educationAndTraining[].organization.label
Mangalore University - (Mangalore, Karnataka, India)

# publications[].label
Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus.

# publications[].label
EFFECT OF YOGA THERAPY ON BODY MASS INDEX AND OXIDATIVE STATUS

# publications[].label
Effect of Electron Beam radiation on Antioxidant status of Swiss albino mice

# publications[].label
Synthesis, molecular docking and biological evaluation of novel bis-pyrazole derivatives for analgesic, anti-inflammatory and antimicrobial activities

# publications[].label
Status of Lipid Perodixation And Sialic Acid in Generelised Vitiligo

# publications[].label
Evaluation of Erythrocyte antioxidant defense enzyme activity in electron beam irradiated mice

# publications[].label
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness.

# publications[].label
EFFECT OF ELECTRON BEAM RADIATION ON HEMATOPOIETIC CELLS OF SWISS ALBINO MICE

# publications[].label
Radioprotective effect of sulphydryl group containing triazole derivative to modulate the radiation- induced clastogenic effects.

# publications[].label
Extracellular Vesicles in the Forebrain Display Reduced miR-346 and miR-331-3p in a Rat Model of Chronic Temporal Lobe Epilepsy.

# publications[].label
ChemInform Abstract: Synthesis of New Pyrazole Derivatives via Multicomponent Reaction and Evaluation of Their Antimicrobial and Antioxidant Activities.

# publications[].label
Synthesis of new indazole derivatives as potential antioxidant agents

# publications[].label
EFFECT OF ELECTRON BEAM RADIATION ON HEMATOPOIETIC CELLS OF SWISS ALBINO MICE

# publications[].label
Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus.

# publications[].label
Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice.

# publications[].label
HUMAN MSC-DERIVED EXTRACELLULAR VESICLE TREATMENT AFTER TBI CAN DIMINISH CHRONIC NEUROINFLAMMATION BY BLOCKING NLRP3 INFLAMMASOME-MEDIATED P38 MAPK SIGNALING CASCADE

# publications[].label
Administrations of Human Astrocytederived EVs in Adulthood Can Promote the Maintenance of Enhanced Cognitive Ability in Early and Late Middle Age

# publications[].label
Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction.

# publications[].label
Intranasal Administration of Extracellular Vesicles from hiPSC-Derived Neural Stem Cells as an Anti-Aging Treatment to Prevent Age-Related Cognitive and Mood Dysfunction

# publications[].label
Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties.

# publications[].label
Proficiency of Extracellular Vesicles From hiPSC-Derived Neural Stem Cells in Modulating Proinflammatory Human Microglia: Role of Pentraxin-3 and miRNA-21-5p.

# publications[].label
Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression.

# publications[].label
Corrigendum: Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf War Illness

# publications[].label
Promise of irisin to attenuate cognitive dysfunction in aging and Alzheimer's disease.

# publications[].label
Validation of DNA Damage Progression with Days after Single Exposure of Sublethal Dosage of Electron Beam Radiation

# publications[].publisher
International Union of Crystallography (IUCr)

# publications[].label
Modulatory effect of Allium sativumEthanolic Extract on Cultured Human Lymphocytes

# publications[].publisher
Journal of Applied Pharmaceutical Science

# publications[].label
Effect of Sub lethal dose electron beam irradiation on Swiss albino mice lung: A pilot Study.

# publications[].label
Novel strategy for the development of radioresistance breast cancer cell line

# publications[].label
Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood.

# publications[].label
Microglial NLRP3 Inflammasomes in Alzheimer's Disease Pathogenesis: From Interaction with Autophagy/Mitophagy to Therapeutics.

# publications[].label
Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.

# publications[].label
Gulf War Illness: Mechanisms Underlying Brain Dysfunction and Promising Therapeutic Strategies.

# publications[].label
Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease.

# publications[].label
A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB signaling.

# publications[].label
Residual microglia following short-term PLX5622 treatment in 5xFAD mice exhibit diminished NLRP3 inflammasome and mTOR signaling, and enhanced autophagy.

# publications[].label
In vitro and In vivo antioxidant property of sulphydryl group containing 1, 2, 4 Triazole derivative

# publications[].label
Radioprotective effect of Nardostachys jatamansi against whole body electron beam induced oxidative stress and tissue injury in rats

# publications[].label
An epidemiology of prevalence of Type 2 Diabetes among the adult residents in Dakshina Kannada district.

# publications[].label
Protective Effect of Nardostachys jatamansi on Radiation Induced Anxiety and Oxidative Stress

# publications[].label
EFFECT OF YOGA THERAPY ON BODY MASS INDEX AND OXIDATIVE STATUS

# publications[].label
Inhibition of Ehrlich ascites cancer, hypoxia-inducible factor-1 alpha, and the kinase insert domain-containing receptor/fms-like tyrosine kinase-binding domains of vascular endothelial growth factor by Thiazole Acetamide Derivatives.

# publications[].label
Radioprotective Properties of Chitosan on Cultured Human Lymphocytes against Electron Beam Radiation

# publications[].label
Synthesis of new pyrazole derivatives via multicomponent reaction and evaluation of their antimicrobial and antioxidant activities

# publications[].label
DIETARY SUPPLEMENTATION OF NATURAL AND SYNTHETIC PRODUCTS REDUCES ANXIETY IN MICE AGAINST ELECTRON BEAM RADIATION INDUCED OXIDATIVE STRESS

# publications[].label
A study on the reactions of alkyl 4,6-bis(4-fluorophenyl)-2-oxocyclohex-3-ene-1-carboxylate and in vitro antioxidant activity of derivatives

# publications[].label
Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus.

# publications[].label
Modeling Neuroinflammation using iMicroglia Differentiated from hiPSCs: Efficacy of NSC-derived Extracellular Vesicles for Modulating Activated Microglia

# publications[].label
Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain.

# publications[].label
Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness.

# publications[].label
Emerging Anti-Aging Strategies - Scientific Basis and Efficacy.

# publications[].label
Intranasal delivery of metformin using metal-organic framework (MOF)-74-Mg nanocarriers.

# publications[].label
FDA-approved cannabidiol [Epidiolex] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis.

# publications[].label
A SINGLE INTRANASAL DOSE OF HUMAN NSC-DERIVED EXTRACELLULAR VESICLES AFTER TBI INHIBITS PROINFLAMMATORY TRANSCRIPTOMIC SIGNATURES IN ASTROCYTES

# publications[].label
Improved Brain Function Mediated by Extracellular Vesicles from hiPSC-NSCs in 5xFAD Mice is Linked with Enhanced Hippocampal Neurogenesis and Reduced mTOR Signaling

# publications[].label
Variations in Serum Myeloperoxidase Levels With Respect To Hyperglycemia, Duration of Diabetes, Bmi, Sex And Aging in Type 2 Diabetes Mellitus

# publications[].label
Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus.

# publications[].label
Oxidative stress, antioxidant status and DNA damage in Type 2 diabetes melittus

# publications[].label
Protective Effect of Nardostachys jatamansi Against Radiation-induced Damage at Biochemical and Chromosomal Levels in Swiss Albino Mice.

# publications[].label
Brain Dysfunction in a Model of Gulf War Illness Continues into Middle Age with Elevated Oxidative Stress and Waned Mitochondrial Activity

# publications[].label
DIETARY SUPPLEMENTATION OF NATURAL AND SYNTHETIC PRODUCTS REDUCES ANXIETY IN MICE AGAINST ELECTRON BEAM RADIATION INDUCED OXIDATIVE STRESS

# publications[].label
No impact on P-gp level in radioresistant MCF-7 cells

# publications[].label
Promise of metformin for preventing age-related cognitive dysfunction.

# publications[].label
Extracellular vesicles from hiPSC-derived NSCs protect human neurons against A-42 oligomers induced neurodegeneration, mitochondrial dysfunction and tau phosphorylation.

# publications[].label
Montelukast Treatment Attenuates Cognitive Dysfunction in a Model of Chronic Gulf War Illness With Modulation of Leukotriene Signaling and NLRP3-Inflammasome Activation

# publications[].label
Rapid synthesis of gold nanoparticles using silk fibroin: characterization, antibacterial activity, and anticancer properties

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine

# schools[]
Texas A&M University Naresh K. Vashisht College of Medicine