# positions[].organizations[].parent[].label
College of Veterinary Medicine and Biomedical Sciences

# positions[].organizations[].parent[].label
School of Veterinary Medicine and Biomedical Sciences

# keywords[]
35 Commerce, Management, Tourism And Services

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
United States Environmental Protection Agency

# keywords[]
3403 Macromolecular And Materials Chemistry

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
United States Environmental Protection Agency

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
Houston Ship Channel Polycyclic Aromatic Hydrocarbons (pahs)

# keywords[]
4019 Resources Engineering And Extractive Metallurgy

# keywords[]
United States Environmental Protection Agency

# keywords[]
United States Environmental Protection Agency

# keywords[]
Stem Cell Research - Induced Pluripotent Stem Cell

# keywords[]
United States Environmental Protection Agency

# keywords[]
Nonalcoholic Fatty Liver Disease (nafld)

# keywords[]
United States Environmental Protection Agency

# keywords[]
Uncertainty Factor For Uncertainty In Extrapolating Animal Data To Humans (i.e., Interspecies Uncertainty) (http://www.epa.gov/iris/)

# keywords[]
Cytochrome P450, Family 2, Subfamily B, Polypeptide 1

# keywords[]
Cytochrome P450, Family 11, Subfamily A, Polypeptide 1

# keywords[]
Cytochrome P450, Family 3, Subfamily A, Polypeptide 1

# keywords[]
Cytochrome P450, Family 17, Subfamily A, Polypeptide 1

# keywords[]
National Institute Of Environmental Health Sciences

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
2.5 Research Design And Methodologies (aetiology)

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
United States Environmental Protection Agency

# keywords[]
In Vitro-to-in Vivo Extrapolation (ivive)

# keywords[]
United States Environmental Protection Agency

# keywords[]
Agency For Toxic Substances And Disease Registry

# keywords[]
No Observed Transcriptional Effect Level

# keywords[]
National Center For Computational Toxicology

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# educationAndTraining[].organization.label
Princeton University - (Princeton, New Jersey, United States)

# educationAndTraining[].field
Science, Technology, and Environmental Policy

# educationAndTraining[].organization.label
Harvard University - (Cambridge, Massachusetts, United States)

# educationAndTraining[].organization.label
Princeton University - (Princeton, New Jersey, United States)

# educationAndTraining[].organization.label
Princeton University - (Princeton, New Jersey, United States)

# publications[].label
New WHO guidance on uncertainty in hazard characterization - A unified tiered approach integrating deterministic and probabilistic methods

# publications[].label
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.

# publications[].label
Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse.

# publications[].label
Standardizing benchmark dose calculations to improve science-based decisions in human health assessments.

# publications[].label
Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization.

# publications[].label
Cardiotoxicity Hazard and Risk Characterization of ToxCast Chemicals Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Multiple Donors.

# publications[].label
Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice.

# publications[].label
Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male Mice.

# publications[].label
Rodent models for studies of genetic diversity and case studies of their use in toxicology

# publications[].label
Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships.

# publications[].label
Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mice.

# publications[].label
Approaches to human health risk assessment based on the signal-to-noise crossover dose.

# publications[].label
The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.

# publications[].label
Developing Dietary Reference Intakes Based on Chronic Disease Summary

# publications[].label
Xenobiotic metabolism in a mouse model of non-alcoholic fatty liver disease: A case study of the ubiquitous environmental contaminant tetrachloroethylene

# publications[].label
High-to-Low Dose Extrapolation: Issues and Approaches

# publications[].label
Dosing Methods to Enable Cell-Based In Vitro Testing of Complex Substances: A Case Study with a PAH Mixture.

# publications[].label
Statistical inferences from serially correlated methylene chloride data

# publications[].label
A tiered, Bayesian approach to estimating of population variability for regulatory decision-making.

# publications[].label
Key scientific issues in the health risk assessment of trichloroethylene.

# publications[].label
Lessons Learned and Reflections on the Statement of Task

# publications[].label
Derivation of Human Toxicokinetic Parameters and Chemical-Specific Adjustment Factor of Citrinin Through a Human Intervention Trial and Hierarchical Bayesian Population Modeling.

# publications[].label
Montmorillonites Can Tightly Bind Glyphosate and Paraquat Reducing Toxin Exposures and Toxicity.

# publications[].label
Trichloroacetic acid: updated estimates of its bioavailability and its contribution to trichloroethylene-induced mouse hepatomegaly.

# publications[].label
Questioning Existing Cancer Hazard Evaluation Standards in the Name of Statistics.

# publications[].label
Physiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse.

# publications[].label
A Unified Probabilistic Framework for Dose-Response Assessment of Human Health Effects.

# publications[].label
Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS).

# publications[].label
Radioactive materials in biosolids: national survey, dose modeling, and publicly owned treatment works (POTW) guidance.

# publications[].label
Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system.

# publications[].label
Incorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in mice.

# publications[].label
Differential toxicity of water versus gavage exposure to trichloroethylene in rats.

# publications[].label
Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene.

# publications[].label
Association between prenatal exposures to ambient air pollution and birthweight

# publications[].label
Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.

# publications[].label
Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling.

# publications[].label
Using Prior Toxicological Data to Support Dose-Response AssessmentIdentifying Plausible Prior Distributions for Dichotomous Dose-Response Models.

# publications[].label
Using Copulas to Introduce Dependence in Dose-Response Modeling of Multiple Binary Endpoints

# publications[].label
Steady-state solutions to PBPK models and their applications to risk assessment I: Route-to-route extrapolation of volatile chemicals - Authors' response to letter by Dr. Kenneth Bogen

# publications[].label
Management of sewage sludge and ash containing radioactive materials

# publications[].label
Key Characteristics of Cardiovascular Toxicants.

# publications[].label
The Current Process to Establish Dietary Reference Intakes

# publications[].label
Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following Inhalation Exposure to 1,3-Butadiene.

# publications[].label
Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals Summary

# publications[].label
Key Characteristics Approach to Carcinogenic Hazard Identification.

# publications[].label
A human population-based organotypic in vitro model for cardiotoxicity screening.

# publications[].label
GRADE Guidelines 30: the GRADE approach to assessing the certainty of modeled evidence-An overview in the context of health decision-making.

# publications[].label
A Comparison of Regulatory Implications of Traditional and Exact Two-Stage DoseResponse Models

# publications[].label
Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites.

# publications[].label
Development and application of a rat PBPK model to elucidate kidney and liver effects induced by ETBE and tert-butanol.

# publications[].label
A framework for the next generation of risk science.

# publications[].label
State-level needs for social distancing and contact tracing to contain COVID-19 in the United States.

# publications[].label
Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice.

# publications[].label
HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston-Galveston-Brazoria Region.

# publications[].tags
16 Peace, Justice and Strong Institutions

# publications[].label
Human health effects of trichloroethylene: key findings and scientific issues.

# publications[].label
Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.

# publications[].label
Trichloroethylene cancer epidemiology: a consideration of select issues.

# publications[].label
State-level needs for social distancing and contact tracing to contain COVID-19 in the United States.

# publications[].label
Benchmark Dose for Urinary Cadmium based on a Marker of Renal Dysfunction: A Meta-Analysis.

# publications[].label
Application of the key characteristics of carcinogens in cancer hazard identification.

# publications[].label
New WHO guidance on uncertainty in hazard characterization - A unified tiered approach integrating deterministic and probabilistic methods

# publications[].label
Comparative analysis of Rapid Equilibrium Dialysis (RED) and solid phase micro-extraction (SPME) methods for In Vitro-In Vivo extrapolation of environmental chemicals.

# publications[].label
Advancing probabilistic risk assessment by integrating human biomonitoring, new approach methods, and Bayesian modeling: A case study with the mycotoxin deoxynivalenol.

# publications[].label
Imidacloprid exposure is detectable in over one third of wild bird samples from diverse Texas ecoregions.

# publications[].label
Development and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans.

# publications[].label
Application of the Navigation Guide systematic review methodology and meta-analysis to evaluate the association between prenatal particulate matter air pollution exposure and birth weight

# publications[].label
Conditional Toxicity Value (CTV) Predictor: An In Silico Approach for Generating Quantitative Risk Estimates for Chemicals.

# publications[].label
Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups.

# publications[].label
Decision-Making with New Approach Methodologies: Time to Replace Default Uncertainty Factors with Data.

# publications[].label
A semianalytic model for cosmological reheating and reionization due to the gravitational collapse of structure

# publications[].label
Modeling of Sensitive Subpopulations and Interindividual Variability in Pharmacokinetics for Health Risk Assessments

# publications[].label
The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions.

# publications[].label
Target Organ Metabolism, Toxicity, and Mechanisms of Trichloroethylene and Perchloroethylene: Key Similarities, Differences, and Data Gaps.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
How to organise a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024.

# publications[].label
A tiered testing strategy based on in vitro phenotypic and transcriptomic data for selecting representative petroleum UVCBs for toxicity evaluation in vivo.

# publications[].label
Characterizing vulnerabilities to climate change across the United States.

# publications[].label
The use of canonical dose-response models for benchmark dose analysis of continuous toxicological data.

# publications[].label
Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood lead levels using the Collaborative Cross mouse population.

# publications[].label
Addressing human variability in next-generation human health risk assessments of environmental chemicals.

# publications[].label
The Process for Establishing Chronic Disease Dietary Reference Intakes

# publications[].label
Beyond the cancer slope factor: Broad application of Bayesian and probabilistic approaches for cancer dose-response assessment.

# publications[].label
Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach.

# publications[].label
Exposure and Toxicity Characterization of Chemical Emissions and Chemicals in Products: Global Recommendations and Implementation in USEtox.

# publications[].label
Characterizing baseline legacy chemical contamination in urban estuaries for disaster-research through systematic evidence mapping: A case study.

# publications[].label
Evaluation of physiologically based pharmacokinetic models for use in risk assessment.

# publications[].label
Bayesian Estimation of Human Population Toxicokinetics of PFOA, PFOS, PFHxS, and PFNA from Studies of Contaminated Drinking Water.

# publications[].label
Polybrominated diphenyl ether (PBDE) neurotoxicity: a systematic review and meta-analysis of animal evidence.

# publications[].label
An approach to using genomics data in risk assessment: Dibutyl phthalate (DBP) case study

# publications[].label
Toxicokinetics of inhaled trichloroethylene and tetrachloroethylene in humans at 1 ppm: empirical results and comparisons with previous studies.

# publications[].label
Recent Advances in Probabilistic Dose-Response Assessment to Inform Risk-Based Decision Making.

# publications[].label
Baseline data for distribution of contaminants by natural disasters: results from a residential Houston neighborhood during Hurricane Harvey flooding.

# publications[].label
Development of an Evidence-Based Risk Assessment Framework.

# publications[].label
Well-tempered MCMC simulations for population pharmacokinetic models.

# publications[].label
A Bayesian population physiologically based pharmacokinetic absorption modeling approach to support generic drug development: application to bupropion hydrochloride oral dosage forms.

# publications[].label
An approximate method for population toxicokinetic analysis with aggregated data

# publications[].label
A systematic approach for identifying and presenting mechanistic evidence in human health assessments.

# publications[].label
Characterization of Compositional Variability in Petroleum Substances.

# publications[].label
An integrative method for identification and prioritization of constituents of concern in produced water from onshore oil and gas extraction.

# publications[].label
Invited Perspective: Uneven Progress Addressing Population Variability in Human Health Risk Assessment.

# publications[].label
Radioactive materials in biosolids: dose modeling.

# publications[].label
In Vitro Bioavailability of the Hydrocarbon Fractions of Dimethyl Sulfoxide Extracts of Petroleum Substances.

# publications[].label
Challenges and opportunities in the risk assessment of existing substances in Canada: lessons learned from the international community

# publications[].label
APROBA-Plus: A probabilistic tool to evaluate and express uncertainty in hazard characterization and exposure assessment of substances.

# publications[].label
Quantitative In Vitro-to-In Vivo Extrapolation for Mixtures: A Case Study of Superfund Priority List Pesticides.

# publications[].label
pksensi: An R package to apply global sensitivity analysis in physiologically based kinetic modeling.

# publications[].label
Modeling the transplacental transfer of small molecules using machine learning: a case study on per- and polyfluorinated substances (PFAS).

# publications[].label
A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.

# publications[].label
Corrigendum to "Polycyclic aromatic hydrocarbon status in post-hurricane Harvey sediments: Considerations for environmental sampling in the Galveston Bay/Houston Ship Channel region" [Mar. Pollut. Bull. 162, (January 2021), 111872].

# publications[].label
Using Test Positivity and Reported Case Rates to Estimate State-Level COVID-19 Prevalence and Seroprevalence in the United States.

# publications[].label
Towards a better consideration of the interindividual variability in chemical risk assessment

# publications[].label
Conceptual and Methodological Challenges in Establishing Chronic Disease Dietary Reference Intakes

# publications[].label
Application of a unified probabilistic framework to the dose-response assessment of acrolein.

# publications[].label
Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.

# publications[].label
A workflow for human health hazard evaluation using transcriptomic data and key Characteristics-Based gene sets.

# publications[].label
Deriving generic distributions from historical data for interspecies, intraspecies, and subchronic-chronic extrapolation, and how to deal with other uncertainties

# publications[].label
Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes.

# publications[].label
Human Health Benefits from Fish Consumption vs. Risks from Inhalation Exposures Associated with Contaminated Sediment Remediation: Dredging of the Hudson River.

# publications[].label
Advancements in Life Cycle Human Exposure and Toxicity Characterization.

# publications[].label
The IARC Monographs: Updated Procedures for Modern and Transparent Evidence Synthesis in Cancer Hazard Identification.

# publications[].label
Risk Characterization of Environmental Samples Using In Vitro Bioactivity and Polycyclic Aromatic Hydrocarbon Concentrations Data.

# publications[].label
Rapid Characterization of Emerging Per- and Polyfluoroalkyl Substances in Aqueous Film-Forming Foams Using Ion Mobility Spectrometry-Mass Spectrometry.

# publications[].label
Potential Human Health Hazard of Post-Hurricane Harvey Sediments in Galveston Bay and Houston Ship Channel: A Case Study of Using In Vitro Bioactivity Data to Inform Risk Management Decisions.

# publications[].label
Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.

# publications[].label
Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment.

# publications[].label
Approaches for applications of physiologically based pharmacokinetic models in risk assessment.

# publications[].label
Polycyclic aromatic hydrocarbon status in post-hurricane Harvey sediments: Considerations for environmental sampling in the Galveston Bay/Houston Ship Channel region.

# publications[].label
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model.

# publications[].label
Calibrating COVID-19 community transmission risk levels to reflect infection prevalence.

# publications[].label
Using cluster abundances and peculiar velocities to test the Gaussianity of the cosmological density field

# publications[].label
Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.

# publications[].label
Two-Stage Machine Learning-Based Approach to Predict Points of Departure for Human Noncancer and Developmental/Reproductive Effects.

# publications[].label
Applying a Global Sensitivity Analysis Workflow to Improve the Computational Efficiencies in Physiologically-Based Pharmacokinetic Modeling.

# publications[].label
Broadening the chemical coverage to derive human toxicity dose-response factors for non-cancer endpoints

# publications[].label
A Bayesian Method for Population-wide Cardiotoxicity Hazard and Risk Characterization Using an In Vitro Human Model.

# publications[].label
Spatial and Temporal Analysis of Impacts of Hurricane Florence on Criteria Air Pollutants and Air Toxics in Eastern North Carolina.

# publications[].label
A Comparative Analysis of Analytical Techniques for Rapid Oil Spill Identification.

# publications[].label
Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry.

# publications[].label
A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures.

# publications[].label
Grouping of Petroleum Substances as Example UVCBs by Ion Mobility-Mass Spectrometry to Enable Chemical Composition-Based Read-Across.

# publications[].label
Polycyclic Aromatic Hydrocarbons in Houston Parks After Hurricane Harvey.

# publications[].label
Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks.

# publications[].label
Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes.

# publications[].label
Statistical inferences from serially correlated methylene chloride data

# publications[].label
What role for biologically based dose-response models in estimating low-dose risk?

# publications[].label
Effect of Polybrominated Diphenyl Ethers on Neurodevelopment

# publications[].label
Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.

# publications[].label
Human health effects of tetrachloroethylene: key findings and scientific issues.

# publications[].label
Methodological Considerations Related to Assessing Intake of Nutrients or Other Food Substances

# publications[].label
Comments on article "Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene" by Clewell and Andersen.

# publications[].label
A Participatory-Based Research Approach for Assessing Exposure to Lead-Contaminated Drinking Water in the Houston Neighborhood of the Greater Fifth Ward.

# publications[].label
Rapid hazard characterization of environmental chemicals using a compendium of human cell lines from different organs.

# publications[].label
Characterizing uncertainty and variability in physiologically based pharmacokinetic models: state of the science and needs for research and implementation.

# publications[].label
Comparative Analysis of Caco-2 Cells and Human Jejunal and Duodenal Enteroid-Derived Cells in Gel- and Membrane-Based Barrier Models of Intestinal Permeability.

# publications[].label
Advancing chemical risk assessment decision-making with population variability data: challenges and opportunities.

# publications[].label
PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in mice.

# publications[].label
Spatial and temporal distribution of surface water contaminants in the Houston Ship Channel after the Intercontinental Terminal Company Fire.

# publications[].label
Beyond the RfD: Broad Application of a Probabilistic Approach to Improve Chemical Dose-Response Assessments for Noncancer Effects.

# publications[].label
The Expected Mass Function for Low-Mass Galaxies in a Cold Dark Matter Cosmology: Is There a Problem?

# publications[].label
Issues in the pharmacokinetics of trichloroethylene and its metabolites.

# publications[].label
An approach for integrating toxicogenomic data in risk assessment: the dibutyl phthalate case study.

# publications[].label
Comparative analysis of metabolism of trichloroethylene and tetrachloroethylene among mouse tissues and strains.

# publications[].label
Strategy for Evaluating Low-Dose Effects

# publications[].label
The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Re: 'Application of the key characteristics of carcinogens in cancer hazard evaluation': response to Goodman, Lynch and Rhomberg.

# publications[].label
Risk Characterization and Probabilistic Concentration-Response Modeling of Complex Environmental Mixtures Using New Approach Methodologies (NAMs) Data from Organotypic in Vitro Human Stem Cell Assays.

# publications[].label
An in vitro-in silico workflow for predicting renal clearance of PFAS.

# publications[].label
Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly.

# publications[].label
Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard.

# publications[].label
Evidence Review: Judging the Evidence for Causal Relationships

# publications[].label
Temporal and spatial analysis of per and polyfluoroalkyl substances in surface waters of Houston ship channel following a large-scale industrial fire incident.

# publications[].label
Evaluating scientific confidence in the concordance of in vitro and in vivo protective points of departure.

# publications[].label
A tiered approach to population-based in vitro testing for cardiotoxicity: Balancing estimates of potency and variability.

# publications[].label
Evaluation of Metabolism of a Defined Pesticide Mixture through Multiple In Vitro Liver Models.

# publications[].label
Issues in using human variability distributions to estimate low-dose risk.

# publications[].label
A general dose-response relationship for chronic chemical and other health stressors and mixtures based on an emergent illness severity model.

# publications[].label
Application of Bayesian and Probabilistic approaches for Cancer Dose-Response Assessment incorporating Model Uncertainty and Human Variability

# publications[].label
Model systems and organisms for addressing inter- and intra-species variability in risk assessment.

# publications[].label
Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes.

# publications[].label
Cumulative Risk Meets Inter-Individual Variability: Probabilistic Concentration Addition of Complex Mixture Exposures in a Population-Based Human In Vitro Model.

# publications[].label
Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse.

# publications[].label
Combining Wilkinson Microwave Anisotropy Probe and Sloan Digital Sky Survey quasar data on reionization constrains cosmological parameters and star formation efficiency

# publications[].label
Biosensor applications in contaminated estuaries: Implications for disaster research response.

# publications[].label
Steady-state solutions to PBPK models and their applications to risk assessment I: Route-to-route extrapolation of volatile chemicals.

# publications[].label
Application of the navigation guide systematic review methodology to evaluate prenatal exposure to particulate matter air pollution and infant birth weight.

# publications[].label
Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance.

# publications[].label
Using test positivity and reported case rates to estimate state-level COVID-19 prevalence and seroprevalence in the United States.

# publications[].label
Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era.

# publications[].label
Intake-Response Relationships and Dietary Reference Intakes for Chronic Disease

# publications[].label
Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice.

# publications[].label
Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals Introduction

# publications[].label
Probabilistic Reference and 10% Effect Concentrations for Characterizing Inhalation Non-cancer and Developmental/Reproductive Effects for 2,160 Substances.

# publications[].label
Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse.

# publications[].label
Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization.

# publications[].label
Cancer risk associated with soil distribution of polycyclic aromatic hydrocarbons within three environmental justice neighborhoods in Houston, Texas.

# publications[].label
Community-facing toxicokineticmodels to estimate PFAS serum levels based on life history and drinking water exposures.

# publications[].label
The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning.

# researcherOn[].label
Comprehensive Tools and Models for Addressing Exposure to Mixtures During Environmental Emergency-Related Contamination Events

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
Texas A&M Center for Environmental Health Research

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
IMSD at Texas A&M University:  Initiative for Maximizing Student Diversity in Biomedical Sciences

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of General Medical Science

# researcherOn[].label
Regulatory Science in Environmental Health and Toxicology

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
TEX-VAL: Texas A&M Tissue Chip Validation Consortium

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
TEX-VAL: Texas A&M Tissue Chip Validation Center

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.label
Environmental Protection Agency - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Cardiotoxicity Adverse Outcome Pathway Center: Organotypic Culture Model and In Vitro-to-In Vivo Extrapolation for High-Throughput Hazard, Dose-Response and Variability Assessments

# researcherOn[].awardedBy.label
Environmental Protection Agency - (Washington D.C., District of Columbia, United States)

# streetAddress
Texas A&M University; Veterinary Physiology and Pharmacology; 4466 TAMU

# organizations[]
College of Veterinary Medicine and Biomedical Sciences

# organizations[]
School of Veterinary Medicine and Biomedical Sciences

# schools[]
College of Veterinary Medicine and Biomedical Sciences

# schools[]
School of Veterinary Medicine and Biomedical Sciences

# inTheNews[].label
Texas A&M Researchers To Address Chemical Pollution Following Gulf Coast Storms

# inTheNews[].label
Environmental risks visualized through new online tools

# inTheNews[].label
New Pandemic Vulnerability Index dashboard maps global spread of COVID-19

# etdChairOf[].label
Cuevas, Carolyn Elizabeth (2017-05). Causes of Death for Law Enforcement Officers in the Line of Duty: A One Health Approach to Trauma Mortality Survivability Assessment. Doctoral Dissertation.

# etdChairOf[].label
Ferguson, Kyle Charles (2018-05). Characterization of Complex Substances Used in Biological Profiling Through Determination of the Free Concentration Within In Vitro Assays. Master's Thesis.