# positions[].organizations[].parent[].label
College of Veterinary Medicine and Biomedical Sciences

# overview
My research is focused on the: 1) investigation of the comparative molecular pathogenesis of zoonotic intracellular bacterial pathogens in natural animal models, particularly brucellosis, salmonellosis, and mycobacterial diseases; 2) development of vaccines and host gene expression-based diagnostics for zoonotic and select agent caused diseases, and especially 3) development of in silico host:pathogen interactome predictive models based upon bi-directional in vivo host (bovine/murine) and Brucella spp., Mycobacterium spp.and Salmonella enterica Typhimurium interactions. We developed an in silico computational infection biology model based on actuall temporal in vivo bovine model microarray-based transcriptomic and proteomic profiling of the acute infectious process. We developed a systems biology analysis of both host and pathogen comprehensive transcriptomic and proteomic datasets derived from our in vivo biological model. We computationally fused the datasets based on actual Salmonella, Brucella and Mycobacterium data and computationally predicted bovine host structural proteins to identify maximum likelihoods of host and pathogen protein:protein interactions as the basis for our preliminary in silico interactome model to predict mechanistic genes and linked perturbed cellular pathways.

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Amplified Fragment Length Polymorphism Analysis

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
3205 Medical Biochemistry And Metabolomics

# keywords[]
Receptors, Tumor Necrosis Factor, Type Ii

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
Dapagliflozin, Diabetic Complication, Diabetic Drug, Hyperglucosuria, Urinary Tract Infection, Uropathogenic Escherichia Coli

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Tarleton State University - (Stephenville, Texas, United States)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# awardsAndHonors[].label
Senator John Melcher, DVM Leadership in Public Policy Award

# publications[].label
Plant-made E2 glycoprotein single-dose vaccine protects pigs against classical swine fever.

# publications[].label
Transcriptional profile of the intracellular pathogen Brucella melitensis following HeLa cells infection.

# publications[].label
Production and use of murine monoclonal antibodies reactive with bovine IgM isotype and IgG subisotypes (IgG1, IgG2a and IgG2b) in assessing immunoglobulin levels in serum of cattle.

# publications[].label
Identification of a genetic region in linked to tolerance to MRSA infection using Collaborative Cross mice

# publications[].label
Adrenal gland size as an index of adrenocortical secretion rate in the California ground squirrel.

# publications[].label
Implementing Digital Pathology into Veterinary Academics and Research.

# publications[].label
Elucidating Mechanisms of Tolerance to Salmonella Typhimurium Across Long-Term Infections Using the Collaborative Cross

# publications[].label
Correlative Gene Expression to Protective Seroconversion in Rift Valley Fever Vaccinates.

# publications[].label
Assessment of bovine mammary gland macrophage oxidative burst activity in a chemiluminescence assay.

# publications[].label
Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi.

# publications[].label
Molecular pathogenesis of Salmonella enterica serotype typhimurium-induced diarrhea.

# publications[].label
Failure of bovine complement levels measured by radial hemolysis to correlate with tube titration.

# publications[].label
Bovine babesiosis: sterile immunity to Babesia bigemina and Babesia argentina infections.

# publications[].label
Amplified fragment length polymorphism reveals specific epigenetic distinctions between Mycobacterium avium subspecies paratuberculosis isolates of various isolation types.

# publications[].label
Global RshDependent Transcription Profile of Brucella Suis During Stringent Response Unravels Adaptation to Nutrient Starvation and CrossTalk with Other Stress Responses

# publications[].label
The role of lysosomes in the pathogenesis of copper-induced hepatotoxicity: morphological studies.

# publications[].label
Bayesian Modeling of MPSS Data: Gene Expression Analysis of Bovine Salmonella Infection.

# publications[].label
THE PRODUCTION OF ANTIIDIOTYPIC MONOCLONAL-ANTIBODIES FOR THE DETECTION OF BRUCELLA-ABORTUS RECEPTORS IN HOST TISSUES

# publications[].label
Virulence associated proteins of Brucella abortus identified by paired two-dimensional gel electrophoretic comparisons of virulent, vaccine and LPS deficient strains.

# publications[].label
Serologic profile for a cow experimentally infected with Brucella abortus.

# publications[].label
Identification of a putative Salmonella enterica serotype typhimurium host range factor with homology to IpaH and YopM by signature-tagged mutagenesis.

# publications[].label
Early phase morphological lesions and transcriptional responses of bovine ileum infected with Mycobacterium avium subsp. paratuberculosis.

# publications[].label
The Salmonella enterica serotype typhimurium effector proteins SipA, SopA, SopB, SopD, and SopE2 act in concert to induce diarrhea in calves.

# publications[].label
Selection experiments to alter disease resistance traits in domestic animals.

# publications[].label
High-throughput Assay to Phenotype Salmonella enterica Typhimurium Association, Invasion, and Replication in Macrophages

# publications[].label
Apoptosis-inducing factor participation in bovine macrophage Mycobacterium bovis-induced caspase-independent cell death.

# publications[].label
Cytoplasmic crystalloids in the ovary of a woolly monkey.

# publications[].label
Identification of Four Genes of the Brucella melitensis ATP Synthase Operon F0 Sector: Relationship with the Rhodospirillaceae Family

# publications[].label
DNA homology of Brucella abortus strains 19 and 2308.

# publications[].label
Salmonella serotype Typhimurium infection of bovine Peyer's patches down-regulates plasma membrane calcium-transporting ATPase expression.

# publications[].label
Serum electrophoretic patterns in the California ground squirrel.

# publications[].label
Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions.

# publications[].label
Ranch Management Factors Associated with Seroprevalence of Neospora caninum Beef Calves

# publications[].label
Capacity of passively administered antibody to prevent establishment of Brucella abortus infection in mice.

# publications[].label
Absence of shedding of two B. abortus strains in goats after vaccination with live vaccines.

# publications[].label
Revised genome sequence of Brucella suis 1330.

# publications[].label
Derivation of monoclonal antibodies against Brucella abortus antigens.

# publications[].label
Taxonomic and metagenomic analyses define the development of the microbiota in the chick

# publications[].label
The lesions of hepatic fatty cirrhosis in sheep.

# publications[].label
Macrophage function in mammary glands of Brucella abortus-infected cows and cows that resisted infection after inoculation of Brucella abortus.

# publications[].label
Methods to improve the health of cattle in the tropics: immunisation and chemoprophylaxis against haemoparasitic infections.

# publications[].label
The role of lysosomes in the pathogenesis of copper-induced hepatotoxicity. II. Intracellular distribution of copper in hepatocytes.

# publications[].label
Natural Resistance Against Brucellosis: A Review

# publications[].label
Caprine abscess model of tulathromycin concentrations in interstitial fluid from tissue chambers inoculated with Corynebacterium pseudotuberculosis following subcutaneous or intrachamber administration.

# publications[].label
A 36-kilodalton Brucella abortus cell envelope protein is encoded by repeated sequences closely linked in the genomic DNA.

# publications[].label
Immunogenic and invasive properties of Brucella melitensis 16M outer membrane protein vaccine candidates identified via a reverse vaccinology approach.

# publications[].label
Recrudescence of Anaplasma marginale induced by immunosuppression with cyclophosphamide.

# publications[].label
Molecular fingerprinting confirms extensive cow-to-cow intra-herd transmission of a single Mycobacterium bovis strain.

# publications[].label
Identification of four genes of the Brucella melitensis ATP synthase operon F0 sector: relationship with the Rhodospirillaceae family.

# publications[].label
Brucella abortus and Pregnancy in Mice: Impact of Chronic Infection on Fertility and the Role of Regulatory T Cells in Tissue Colonization.

# publications[].label
A complex pattern of microsatellite polymorphism within the bovine NRAMP1 gene.

# publications[].label
Comparative analysis of the early transcriptome of Brucella abortus--infected monocyte-derived macrophages from cattle naturally resistant or susceptible to brucellosis.

# publications[].label
Monoclonal antibodies to the bovine immunoglobulin G2a allotypes A1 and A2.

# publications[].label
Brucella melitensis global gene expression study provides novel information on growth phase-specific gene regulation with potential insights for understanding Brucella:host initial interactions.

# publications[].label
Use of propofol, isoflurane and morphine for prolonged general anesthesia in calves

# publications[].label
Correlation of field strain exposure with new cases of brucellosis in six beef herds vaccinated with strain 19.

# publications[].label
Relationship of fetal age at conjunctival exposure of pregnant heifers and Brucella abortus isolation.

# publications[].label
Elucidating Mechanisms of Tolerance to Salmonella Typhimurium across Long-Term Infections Using the Collaborative Cross.

# publications[].label
Global Rsh-dependent transcription profile of Brucella suis during stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses.

# publications[].label
Experimental infection of captive axis deer with Brucella abortus.

# publications[].label
Induction of lymphocyte responsiveness by the outer membrane-peptidoglycan complex of rough strains of Brucella abortus.

# publications[].label
Special Issues around Veterinary Vaccines

# publications[].label
Clinicopathological aspects of imidocarb dipropionate toxicity in horses.

# publications[].label
Humoral and cell-mediated immune responses in chickens with infectious bursal disease.

# publications[].label
Brucella-induced abortions and infection in bottlenose dolphins (Tursiops truncatus).

# publications[].label
Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection.

# publications[].label
Effect of neonatal thymectomy and antilymphocyte globulin on non-specific mitogen stimulation in Holstein-Friesian calves.

# publications[].label
SdiA, an N-acylhomoserine lactone receptor, becomes active during the transit of Salmonella enterica through the gastrointestinal tract of turtles.

# publications[].label
The capsule encoding the viaB locus reduces interleukin-17 expression and mucosal innate responses in the bovine intestinal mucosa during infection with Salmonella enterica serotype Typhi.

# publications[].label
Correction: Correlative Gene Expression to Protective Seroconversion In Rift Valley Vaccinates.

# publications[].label
Genes associated with innate killing of Brucella abortus and Mycobacterium bovis by macrophages from genetically resistant cattle

# publications[].label
Association of serologic status for Neospora caninum with postweaning weight gain and carcass measurements in beef calves.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Characterization of the heat shock response in Brucella abortus and isolation of the genes encoding the GroE heat shock proteins.

# publications[].label
Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation.

# publications[].label
Legionnaires' Disease Mortality in Guinea Pigs Involves the p45 Mobile Genomic Element.

# publications[].label
Immunochemical studies on the binding properties of Brucella abortus lipopolysaccharides to bovine precipitating antibodies.

# publications[].label
Contribution of Salmonella typhimurium virulence factors to diarrheal disease in calves.

# publications[].label
Protection against Brucella abortus in mice with O-polysaccharide-specific monoclonal antibodies.

# publications[].label
The pathology of brucellosis reflects the outcome of the battle between the host genome and the Brucella genome.

# publications[].label
Upregulation of thymosin beta-10 by Mycobacterium bovis infection of bovine macrophages is associated with apoptosis.

# publications[].label
Natural disease resistance in domestic animals.

# publications[].label
Taxonomic and Metagenomic Analyses Define the Development of the Microbiota in the Chick.

# publications[].label
SDS-soluble and peptidoglycan-bound proteins in the outer membrane-peptidoglycan complex of Brucella abortus.

# publications[].label
Diagnosis of foot-and mouth disease by real time reverse transcription polymerase chain reaction under field conditions in Brazil.

# publications[].label
Evolution of host adaptation in Salmonella enterica.

# publications[].label
The Salmonella enterica serotype Typhi Vi capsular antigen is expressed after the bacterium enters the ileal mucosa.

# publications[].label
An antigenic and serologic comparison of two virulent strains and an attenuated strain of Anaplasma marginale.

# publications[].label
Multicopy Single-Stranded DNA Directs Intestinal Colonization of Enteric Pathogens.

# publications[].label
Nitric oxide not apoptosis mediates differential killing of Mycobacterium bovis in bovine macrophages.

# publications[].label
Ultrastructural renal lesions in goats given a lethal dose of imidocarb diproprionate.

# publications[].label
Safety and immunogenicity of recombinant Rift Valley fever MP-12 vaccine candidates in sheep.

# publications[].label
Babesia bigemina: immune response of cattle inoculated with irradiated parasites.

# publications[].label
Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300

# publications[].label
Vaccine comprising Brucella abortus which has O polysaccharide antigen absent

# publications[].label
Comparisons of the complement-fixation and indirect fluorescent antibody reactions in the detection of bovine babesiasis.

# publications[].label
A multiplex approach to molecular detection of Brucella abortus and/or Mycobacterium bovis infection in cattle.

# publications[].label
Comparison of C18-carboxypropylbetaine and glass bead DNA extraction methods for detection of Mycobacterium bovis in bovine milk samples and analysis of samples by PCR.

# publications[].label
Genetic background influences survival of infections with Salmonella enterica serovar Typhimurium in the Collaborative Cross.

# publications[].label
Influence of dexamethasone on the recrudescence of Anaplasma marginale in splenectomized calves.

# publications[].label
A study of the toxicity of imidocarb dipropionate in cattle.

# publications[].label
Failure to identify non-bovine reservoirs of Mycobacterium bovis in a region with a history of infected dairy-cattle herds.

# publications[].label
DIFFERENTIAL RECOGNITION OF BRUCELLAE BY BOVINE T-CELLS

# publications[].label
Ranch-management factors associated with antibody seropositivity for Neospora caninum in consignments of beef calves in Texas, USA.

# publications[].label
Role of SPI-1 secreted effectors in acute bovine response to Salmonella enterica Serovar Typhimurium: a systems biology analysis approach.

# publications[].label
Interspecific transmission of Brucella abortus from experimentally infected coyotes (Canis latrans) to parturient cattle.

# publications[].label
Immunological response to the Brucella abortus GroEL homolog.

# publications[].label
Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth.

# publications[].label
Chemoprophylaxis (Imidocarb) against Babesia bigemina and Babesia argentina infections.

# publications[].label
Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus x Bos indicus, sentinels near industrial facilities.

# publications[].label
Late-life dietary folate restriction reduces biosynthesis without compromising healthspan in mice.

# publications[].label
STRUCTURAL AND IMMUNOCHEMICAL ASPECTS OF BRUCELLA-ABORTUS ENDOTOXINS

# publications[].label
Bovine natural resistance macrophage protein 1 (NRAMP1) gene

# publications[].label
Secreted effector proteins of Salmonella enterica serotype typhimurium elicit host-specific chemokine profiles in animal models of typhoid fever and enterocolitis.

# publications[].label
Modulation of the bovine trophoblastic innate immune response by Brucella abortus.

# publications[].label
Salmonella enterica serotype Typhimurium and its host-adapted variants.

# publications[].label
Multi-comparative systems biology analysis reveals time-course biosignatures of in vivo bovine pathway responses to B.melitensis, S.enterica Typhimurium and M.avium paratuberculosis.

# publications[].label
Comparison of results from five serologic methods used for detecting Brucella abortus antibody activity in coyote sera.

# publications[].label
Brucella abortus in coyotes. I. A serologic and bacteriologic survey in eastern Texas.

# publications[].label
Clinical, histologic, and histochemical study of imidocarb diproprionate toxicosis in goats.

# publications[].label
Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection.

# publications[].label
Salmonella uses energy taxis to benefit from intestinal inflammation.

# publications[].label
Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection.

# publications[].label
Diagnostic specificity of a real-time RT-PCR in cattle for foot-and-mouth disease and swine for foot-and-mouth disease and classical swine fever based on non-invasive specimen collection.

# publications[].label
Late-life dietary folate restriction reduces biosynthetic processes without compromising healthspan in mice.

# publications[].label
Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2.

# publications[].label
Response to neonatally thymectomized Holstein calves to bacille Calmette Gurin.

# publications[].label
Human Brucellosis and Adverse Pregnancy Outcomes.

# publications[].label
Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.

# publications[].label
Comparative efficacy of oxytetracycline and a dithiosemicarbazone in eliminating Anaplasma marginale infection in splenectomized calves.

# publications[].label
Vaginal Inoculation of Uropathogenic Escherichia coli during Estrus Leads to Genital and Renal Colonization.

# publications[].label
The attenuated sopB mutant of Salmonella enterica serovar Typhimurium has the same tissue distribution and host chemokine response as the wild type in bovine Peyer's patches.

# publications[].label
Improved variation calling via an iterative backbone remapping and local assembly method for bacterial genomes.

# publications[].label
Experimental induction of hemorrhagic-aplastic anemia in chickens. I. Etiology.

# publications[].label
Hematologic and serum biochemical changes in Salmonella ser Typhimurium-infected calves.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival.

# publications[].label
Conservation of germ plasm from bison infected with Brucella abortus.

# publications[].label
Effects of shipping and storage conditions of fecal samples on viability of Mycobacterium paratuberculosis.

# publications[].label
Salmonella enterica Typhimurium SipA induces CXC-chemokine expression through p38MAPK and JUN pathways.

# publications[].label
Structural and immunochemical aspects of Brucella abortus endotoxins.

# publications[].label
Identification of a polymorphic nucleotide in oxyR specific for Mycobacterium bovis.

# publications[].label
Differential diagnostic assay for brucellosis

# publications[].label
Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Selected examples of emerging and reemerging infectious diseases in animals - Three diseases have significance for both animals and humans

# publications[].label
DNA sequence and expression of the 36-kilodalton outer membrane protein gene of Brucella abortus.

# publications[].label
The myth of Brucella L-forms and possible involvement of Brucella penicillin binding proteins (PBPs) in pathogenicity.

# publications[].label
The chemotherapeutic efficacy of imidocarb dihydrochloride on concurrent bovine anaplasmosis and babesiosis. I. The effects of a single treatment.

# publications[].label
VirB12 is a serological marker of Brucella infection in experimental and natural hosts.

# publications[].label
Systems biology analysis of gene expression during in vivo Mycobacterium avium paratuberculosis enteric colonization reveals role for immune tolerance.

# publications[].label
Effect of dose of Brucella abortus strain 19 in yearling heifers on the relative risk of developing brucellosis from challenge exposure with strain 2308.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Failure to isolate Brucella abortus from embryos or ova from culture-positive superovulated cows.

# publications[].label
Intracellular survival of Brucella abortus, Mycobacterium bovis BCG, Salmonella dublin, and Salmonella typhimurium in macrophages from cattle genetically resistant to Brucella abortus.

# publications[].label
Salmonella-induced cell death is not required for enteritis in calves.

# publications[].label
Morphologic and cytokine profile characterization of Salmonella enterica serovar typhimurium infection in calves with bovine leukocyte adhesion deficiency.

# publications[].label
CLONING THE GENES ENCODING THE MAJOR OUTER-MEMBRANE PROTEIN OMP III OF BRUCELLA-ABORTUS VACCINE AND VIRULENT-STRAINS

# publications[].label
Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosis.

# publications[].label
The use of flow cytometry to detect expression of subunits encoded by 11 Salmonella enterica serotype Typhimurium fimbrial operons.

# publications[].label
Controlled release vaccines and methods for treating Brucella diseases and disorders

# publications[].label
Viral particles associated with malignant catarrhal fever in deer.

# publications[].label
Comparison of genome diversity of Brucella spp. field isolates using Universal Bio-signature Detection Array and whole genome sequencing reveals limitations of current diagnostic methods.

# publications[].label
Phage mediated horizontal transfer of the sopE1 gene increases enteropathogenicity of Salmonella enterica serotype Typhimurium for calves.

# publications[].label
Influence of interferon in natural resistance of mice to Sendai virus pneumonia.

# publications[].label
A species independent universal bio-detection microarray for pathogen forensics and phylogenetic classification of unknown microorganisms.

# publications[].label
BOVINE BRUCELLOSIS RESEARCH - AN OVERVIEW OF THE TEXAS-AGRICULTURAL-EXPERIMENT-STATION PROGRAM

# publications[].label
Vaccination with attenuated Salmonella enterica Dublin expressing E coli O157:H7 outer membrane protein Intimin induces transient reduction of fecal shedding of E coli O157:H7 in cattle.

# publications[].label
Evaluation of novel Brucella melitensis unmarked deletion mutants for safety and efficacy in the goat model of brucellosis.

# publications[].label
High-throughput assay to phenotype Salmonella enterica Typhimurium association, invasion, and replication in macrophages.

# publications[].label
Relationship of days in gestation at exposure and development of brucellosis in strain 19-vaccinated heifers.

# publications[].label
Salmonella Pathogenicity Island 1 Is Expressed in the Chicken Intestine and Promotes Bacterial Proliferation.

# publications[].label
Immunochemical Analysis of Lipopolysaccharides with 2-D Gel Electrophoresis and Monoclonal Antibodies

# publications[].label
Immunogenicity of a recombinant Rift Valley fever MP-12-NSm deletion vaccine candidate in calves.

# publications[].label
Naturally occurring trypanosomiasis (Chagas' disease) in dogs.

# publications[].label
Serologic response in bottlenose dolphins Tursiops truncatus infected with Brucella sp. using a dolphin-specific indirect ELISA.

# publications[].label
Development of real-time diagnostic assays specific for Mycoplasma mycoides subspecies mycoides Small Colony.

# publications[].label
Altered host immune responses to membrane vesicles from Salmonella and Gram-negative pathogens.

# publications[].label
An experimental infection of Trypanosoma cruzi in striped skunks (Mephitis mephitis).

# publications[].label
Hemoparasitism, humoral immunodeficiency, and an IgG1 fragment in a cow.

# publications[].label
Immunogenicity of subcellular fractions of Brucella abortus: measurement by in vitro lymphocyte proliferative responses.

# publications[].label
Combination thin and thick blood films for the detection of Babesia parasitemia.

# publications[].label
The spv genes on the Salmonella dublin virulence plasmid are required for severe enteritis and systemic infection in the natural host.

# publications[].label
EARLY REMOVAL OF COWS WITH BRUCELLOSIS AND THE EFFECT IN STRAIN-19 VACCINATED CATTLE HERDS

# publications[].label
Borrelia burgdorferi engages mammalian type I interferon responses via the cGAS-STING pathway

# publications[].label
Survival of smooth, rough and transposon mutant strains of Brucella abortus in bovine mammary macrophages.

# publications[].label
The chemotherapeutic efficacy of imidocarb dihydrochloride on concurrent bovine anaplasmosis and babesiosis. II. The effects of multiple treatments.

# publications[].label
Survival of rough and smooth strains of Brucella abortus in bovine mammary gland macrophages.

# publications[].label
Genetic resistance to bacterial diseases of animals.

# publications[].publisher
O.I.E (World Organisation for Animal Health)

# publications[].label
Systems biology analysis of Brucella infected Peyer's patch reveals rapid invasion with modest transient perturbations of the host transcriptome.

# publications[].label
Sensitivity of serological methods for detecting antibody in vaccinated and non-vaccinated Brucella-infected cows.

# publications[].label
Pathologic findings and association of Mycobacterium bovis infection with the bovine NRAMP1 gene in cattle from herds with naturally occurring tuberculosis.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Salmonella enterica serovar Typhimurium-induced internalization and IL-8 expression in HeLa cells does not have a direct relationship with intracellular Ca(2+) levels.

# publications[].label
Babesia bigemina, Babesia argentina, and Anaplasma marginale: Coinfectious immunity in bovines.

# publications[].label
Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC.

# publications[].label
RESPONSE TO THE CRITIQUE OF BRUCELLOSIS IN CAPTIVE BISON

# publications[].label
Molecular epidemiology of Mycobacterium bovis in Texas and Mexico.

# publications[].label
A school-based intervention for diabetes risk reduction.

# publications[].label
Transcriptome analysis of HeLa cells response to Brucella melitensis infection: a molecular approach to understand the role of the mucosal epithelium in the onset of the Brucella pathogenesis.

# publications[].label
Selective amplification of Brucella melitensis mRNA from a mixed host-pathogen total RNA.

# publications[].label
Rapid and sensitive detection of Mycobacterium avium subsp. paratuberculosis in bovine milk and feces by a combination of immunomagnetic bead separation-conventional PCR and real-time PCR.

# publications[].label
A fiber optic-nanophotonic approach to the detection of antibodies and viral particles of COVID-19

# publications[].label
Impairment of D-alanine biosynthesis in Mycobacterium smegmatis determines decreased intracellular survival in human macrophages.

# publications[].label
Host restriction of Salmonella enterica serotype Typhi is not caused by functional alteration of SipA, SopB, or SopD.

# publications[].label
Global Analysis of the Mycobacterium Avium Subsp. Paratuberculosis Genome and Model Systems Exploring Hostagent Interactions

# publications[].label
Effects of cyclophosphamide on the lymphoid tissues and humoral and cellular immune responsiveness of young calves.

# publications[].label
Ability of mononuclear phagocytes from cattle naturally resistant or susceptible to brucellosis to control in vitro intracellular survival of Brucella abortus.

# publications[].label
Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300.

# publications[].label
Rescuing valuable genomes by animal cloning: a case for natural disease resistance in cattle.

# publications[].label
Chapter 16 Special Issues around Veterinary Vaccines

# publications[].label
Genetic background influences survival of infections with Salmonella enterica serovar Typhimurium in the Collaborative Cross

# publications[].label
virB-Mediated survival of Brucella abortus in mice and macrophages is independent of a functional inducible nitric oxide synthase or NADPH oxidase in macrophages.

# publications[].label
Amplified fragment length polymorphism reveals genomic variability among Mycobacterium avium subsp. paratuberculosis isolates.

# publications[].label
Hepatic fatty cirrhosis in ruminants from western Texas.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Modulation of the intracellular survival of Brucella abortus by tuftsin and muramyl dipeptide.

# publications[].label
Differential reactivity of bovine lymphocytes to species of Brucella.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
In vivo and in vitro diagnosis of Mycobacterium bovis infection.

# publications[].publisher
O.I.E (World Organisation for Animal Health)

# publications[].label
Salmonella enterica serovar typhimurium induces cell death in bovine monocyte-derived macrophages by early sipB-dependent and delayed sipB-independent mechanisms.

# publications[].label
The long-term culture of bovine monocyte-derived macrophages and their use in the study of intracellular proliferation of Brucella abortus.

# publications[].label
The isolation, separation and preservation of Babesia bigemina.

# publications[].label
Molecular Epidemiologic and Geographic Information System Analyses of Mycobacterium bovis Isolates from North America

# publications[].label
Evaluation of the indirect fluorescent antibody test for detecting Trypanosoma vivax in South American cattle.

# publications[].label
In vitro and in vivo immune responses in neonatally thymectomized Holstein-Friesian calves exposed to bovine viral diarrhea virus.

# publications[].label
Of mice, calves, and men. Comparison of the mouse typhoid model with other Salmonella infections.

# publications[].label
Effects of stage of gestation and breed on bovine responses to vaccination with Brucella abortus strain 19.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Bovine T-lymphocyte lines reactive with Brucella abortus.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
SipA, SopA, SopB, SopD, and SopE2 contribute to Salmonella enterica serotype typhimurium invasion of epithelial cells.

# publications[].label
Host-derived nitrate boosts growth of E. coli in the inflamed gut.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Brucella abortus in captive bison. I. Serology, bacteriology, pathogenesis, and transmission to cattle.

# publications[].label
Supplementation with Abscisic Acid Reduces Malaria Disease Severity and Parasite Transmission.

# publications[].publisher
American Society of Tropical Medicine and Hygiene

# publications[].label
Bovine natural resistance associated macrophage protein 1 (Nramp1) gene.

# publications[].label
Effect of stage of gestation on efficacy of Brucella abortus strain-19 vaccination in cattle.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Gut inflammation provides a respiratory electron acceptor for Salmonella.

# publications[].label
The pathogenicity of Brucella suis biovar 4 for bison.

# publications[].label
VALUE OF SEROLOGIC REACTIONS AT 2 MONTHS FOLLOWING STRAIN-19 VACCINATION OF CATTLE HERDS WITH BRUCELLOSIS

# publications[].label
Evaluation of an in vitro technique for quantitative assay of adrenocortical secretion in the California ground squirrel.

# publications[].label
Complete genome sequence of Brucella suis VBI22, isolated from bovine milk.

# publications[].label
CsgA is a pathogen-associated molecular pattern of Salmonella enterica serotype Typhimurium that is recognized by Toll-like receptor 2.

# publications[].label
PREVENTION OF BRUCELLOSIS IN BEEF-CATTLE

# publications[].label
Immune responsiveness and lymphoreticular morphology in cattle fed hypo- and hyperalimentative diets.

# publications[].label
Host-Brucella interactions and the Brucella genome as tools for subunit antigen discovery and immunization against brucellosis.

# publications[].label
Systems Analysis of Early Host Gene Expression Provides Clues for Transient Mycobacterium avium ssp avium vs. Persistent Mycobacterium avium ssp paratuberculosis Intestinal Infections.

# publications[].label
Enhancing the role of veterinary vaccines reducing zoonotic diseases of humans: linking systems biology with vaccine development.

# publications[].label
Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine.

# publications[].label
Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice.

# publications[].label
Characterization of a phosphomonoesterase from Brucella abortus.

# publications[].label
Pathogenesis and immunobiology of brucellosis: review of Brucella-host interactions.

# publications[].label
Salmonella enterica serotype Typhimurium ShdA is an outer membrane fibronectin-binding protein that is expressed in the intestine.

# publications[].label
Morphologic and molecular characterization of Salmonella typhimurium infection in neonatal calves.

# publications[].label
Impact of Horizontal Gene Transfer on the Evolution of Salmonella Pathogenesis

# publications[].label
Spatial associations among density of cattle, abundance of wild canids, and seroprevalence to Neospora caninum in a population of beef calves.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Hyperglucosuria induced by dapagliflozin augments bacterial colonization in the murine urinary tract.

# publications[].label
Methods to improve the health of cattle in the tropics: conclusions and economic appraisal.

# publications[].label
Brucella attenuation and relevance to vaccine properties

# publications[].label
Hepatic fatty cirrhosis in Texas white-tailed deer.

# publications[].label
Mechanisms of binding of Brucella abortus to mononuclear phagocytes from cows naturally resistant or susceptible to brucellosis.

# publications[].label
Serum complement and blood platelet adhesiveness in acute canine ehrlichiosis.

# publications[].label
Life in the inflamed intestine, Salmonella style.

# publications[].label
Salmonella typhimurium leucine-rich repeat proteins are targeted to the SPI1 and SPI2 type III secretion systems.

# publications[].label
Host restriction of Salmonella enterica serotype Typhimurium pigeon isolates does not correlate with loss of discrete genes.

# publications[].label
Brucella abortus in Bison. II. Evaluation of strain 19 vaccination of pregnant cows.

# publications[].label
SIZE, CHARGE AND STRUCTURAL HETEROGENEITY OF BRUCELLA-ABORTUS LIPOPOLYSACCHARIDES DEMONSTRATED BY 2-D GEL-ELECTROPHORESIS

# publications[].label
Putting together a scientific team: collaborative science.

# publications[].label
Cystitis and ataxia associated with sorghum ingestion by horses.

# researcherOn[].label
Veterinary Medical Student Research Training

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Small Animal Model Vaccines and Pathogenesis - BA 23-1171

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Allergy and Infectious Diseases

# researcherOn[].label
The National Center of Excellence for Zoonotic and Animal Disease Defense

# researcherOn[].awardedBy.label
United States Department of Homeland Security - (New York, New York, United States)

# researcherOn[].label
From the Bench to the Shop: Creation and Implementation of a Scientific Business Development Management Program to Transition High Consequence Livestock Disease Research and Development Technology for Commercialization

# researcherOn[].awardedBy.label
United States Department of Homeland Security - (New York, New York, United States)

# streetAddress
Texas A&M University; Vet Med Pathobiology; 4467 TAMU

# organizations[]
College of Veterinary Medicine and Biomedical Sciences

# organizations[]
"College of Veterinary Medicine and Biomedical Sciences"@en-US

# schools[]
College of Veterinary Medicine and Biomedical Sciences

# schools[]
"College of Veterinary Medicine and Biomedical Sciences"@en-US

# etdChairOf[].label
Lozano Alarcon, Fernando (1979-03). A morphologic and immunologic study of Babesia bigemina infected cattle. Doctoral Dissertation.

# etdChairOf[].label
Bissett, Wesley Thurlow, Jr. (2007-12). Ecosystem health at the texas coastal bend: a spatial analysis of exposure and response. Doctoral Dissertation.

# etdChairOf[].label
Figueiredo, Josely Ferreira (2007-05). Molecular pathogenesis of Salmonella enterica serotype Typhimurium-induced inflammatory responses. Doctoral Dissertation.

# etdChairOf[].label
Tran, Quynh Tien-Ngoc (2009-08). The Regulation of Salmonella Typhi Vi Capsular Antigen Expression in Intestinal Model Epithelia and the Bovine Ligated-Ileal Loop Model. Doctoral Dissertation.

# etdChairOf[].label
Rossetti, Carlos Alberto (2007-08). Host and pathogen transcriptional profiles of acute Brucella melitensis infection. Doctoral Dissertation.

# etdChairOf[].label
Gull, Tamara Brownsey (2007-12). In vivo infection biology of contagious bovine pleuropneumonia. Doctoral Dissertation.

# etdChairOf[].label
Gomez, Gabriel (2013-05). Identification and Evaluation of Brucella Recombinant Outer Membrane Proteins as Subunit Vaccinogen Candidates in the Mouse Model of Brucellosis. Doctoral Dissertation.

# etdChairOf[].label
Sivula, Christine Patricia (2008-08). Comparison of cecal colonization of Salmonella enterica serotype Typhimurium in white leghorn chicks and Salmonella-resistant mice. Master's Thesis.

# etdChairOf[].label
Nunes, Jairo Santos (2007-12). The role of neutrophil recruitment in the pathogenesis of salmonella enterica serotype typhimurium-induced enteritis in calves. Doctoral Dissertation.