# positions[].organizations[].parent[].label
School of Veterinary Medicine and Biomedical Sciences

# overview
Transcriptional control of the Ah receptor-regulated gene expression. Interaction between the Ah receptor and NF-kB signal transduction pathways. lncRNAs and their role in regulation of gene expression

# keywords[]
Positive Transcriptional Elongation Factor B

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Growth Hormone Secretagogue Receptor (ghs-r)

# keywords[]
Networking And Information Technology R&d

# keywords[]
Atp Binding Cassette Transporter, Subfamily B, Member 1

# educationAndTraining[].organization.label
South China Agricultural University - (Guangzhou, China)

# educationAndTraining[].organization.label
South China Agricultural University - (Guangzhou, China)

# educationAndTraining[].organization.label
Rutgers University - (New Brunswick, New Jersey, United States)

# publications[].label
Effects of induced stress from the live LaSota Newcastle disease vaccination on the growth performance and immune function in broiler chickens.

# publications[].label
Diversity and distribution of CYP gene family in Bactrian camel.

# publications[].label
The aldo-keto reductase Akr1b7 gene is a common transcriptional target of xenobiotic receptors pregnane X receptor and constitutive androstane receptor.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
Epigenetic sensitization of pregnane X receptor-regulated gene expression by dimethyl sulfoxide.

# publications[].label
Bayesian modeling of ChIP-chip data using latent variables.

# publications[].label
Ah receptor and NF-kappaB interplay on the stage of epigenome.

# publications[].label
Regulation of estrogen receptor mRNA by 2,3,7,8-tetrachlorodibenzo-p-dioxin as measured by competitive RT-PCR.

# publications[].label
A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals.

# publications[].label
Pregnane X receptor as the "sensor and effector" in regulating epigenome.

# publications[].label
Functions of pregnane X receptor in self-detoxification.

# publications[].label
Aconitine induces cell apoptosis via mitochondria and death receptor signaling pathways in hippocampus cell line.

# publications[].label
Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1.

# publications[].label
A cell-based assay for screening inducers of cytochrome P450 3A4 and analyzing transcriptional regulation by pregane X receptor (PXR).

# publications[].label
EZH2 and Endometrial Cancer Development: Insights from a Mouse Model.

# publications[].label
Epigenetic regulation of transcriptional activity of pregnane X receptor by protein arginine methyltransferase 1.

# publications[].label
Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.

# publications[].label
The PI3K/Akt/mTOR signaling pathway plays a role in regulating aconitine-induced autophagy in mouse liver.

# publications[].label
Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action

# publications[].label
Interactions between the aryl hydrocarbon receptor and P-TEFb. Sequential recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoter.

# publications[].label
Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice.

# publications[].label
Xenobiotic receptor meets NF-kappaB, a collision in the small bowel.

# publications[].label
Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice.

# publications[].label
Betulinic acid attenuates dexamethasone-induced oxidative damage through the JNK-P38 MAPK signaling pathway in mice.

# publications[].label
Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action.

# publications[].label
Pregnane X receptor protects HepG2 cells from BaP-induced DNA damage.

# publications[].label
Air pollution and children's health-a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter.

# publications[].label
Histopathology and the detection of avian bornavirus in the nervous system of birds diagnosed with proventricular dilatation disease.

# publications[].label
Procyanidins B2 reverses the T-2 toxin-induced mitochondrial apoptosis in TM3 Leydig cells

# publications[].label
Mice lacking adenosine 2A receptor reveal increased severity of MCD-induced NASH.

# publications[].label
Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome.

# publications[].label
scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation.

# publications[].label
scTenifoldKnk: An Efficient Virtual Knockout Tool for Gene Function Predictions via Single-Cell Gene Regulatory Network Perturbation

# publications[].label
Alpha-ketoglutarate suppresses the NF-B-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway.

# publications[].label
Swainsonine induces autophagy via PI3K/AKT/mTOR signaling pathway to injure the renal tubular epithelial cells.

# publications[].label
Cell GHS-R Regulates Insulin Secretion and Sensitivity.

# publications[].label
Epigenetic regulation of pregnane X receptor activity.

# publications[].label
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[]-pyrene-induced DNA damage.

# publications[].label
scTenifoldKnk: an efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation

# publications[].label
Mechanism of suppression of cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide.

# publications[].label
Regulation of CYF1A1 transcription elongation by aft receptor through interaction with P-TEF B.

# publications[].label
Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.

# publications[].label
Ah receptor and NF-kappaB interactions: mechanisms and physiological implications.

# publications[].label
Interaction between Microbes and Host Intestinal Health: Modulation by Dietary Nutrients and Gut-Brain-Endocrine-Immune Axis

# publications[].label
Ah receptor and NF-kappaB interactions, a potential mechanism for dioxin toxicity.

# publications[].label
Development of High Capacity Enterosorbents for Aflatoxin B1 and Other Hazardous Chemicals.

# publications[].label
Long noncoding RNA MALAT1 regulates generation of reactive oxygen species and the insulin responses in male mice.

# publications[].label
Contributions of the Interaction Between Dietary Protein and Gut Microbiota to Intestinal Health.

# publications[].label
T-2 toxin regulates steroid hormone secretion of rat ovarian granulosa cells through cAMP-PKA pathway.

# publications[].label
Does ATP promote or protect cells from apoptosis?

# publications[].label
Regulation of Xenobiotic Sensor PXR and AhR by NF-kappa B and Its Roles in Xenobiotic Detoxification and Inflammation-Associated Carcinogenesis

# publications[].label
Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance.

# publications[].label
Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells.

# publications[].label
CRISPR/Cas9 genome editing technology in filamentous fungi: progress and perspective.

# researcherOn[].label
Long noncoding RNA MALAT1 ablation reverses sepsis in mouse: epitranscriptomic mechanisms and therapeutic application

# researcherOn[].awardedBy.label
National Institute of Allergy and Infectious Diseases - (Bethesda, Maryland, United States)

# streetAddress
Texas A&M University; Vet Med - Physiology & Pharmacology; 4466 TAMU

# schools[]
School of Veterinary Medicine and Biomedical Sciences