# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# overview
My areas of interest include evidence-based practice and policy, and the application of advanced randomized trial, systematic review, meta-analysis and guideline recommendation methods to a wide range of applied health science topics, with a particular interest in nutrition and health behavior. As the Director and Co-founder of the EvidenceBasedNutrition.org program, I work with an international consortium of researchers, research trainees and educators to develop evidence-based nutrition learning resources, and to conduct high quality systematic reviews and nutritional/lifestyle guideline recommendations on major nutrition, food, dietary pattern and health behavior questions. As both first and senior author, my work has been published in the Journal of the American Medical Association (JAMA), British Medical Journal (BMJ), Annals of Internal Medicine and The Cochrane Library. My Google H-Index is 63, and my groups work has been cited over 22,000 times.

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3.1 Primary Prevention Interventions To Modify Behaviours Or Promote Wellbeing

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Grade, Grading Of Recommendation Assessment, Development, And Evaluation

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Quick Mild Cognitive Impairment (qmci) Screen

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3.1 Primary Prevention Interventions To Modify Behaviours Or Promote Wellbeing

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8.4 Research Design And Methodologies (health Services)

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8.3 Policy, Ethics, And Research Governance

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Randomized Controlled Trials As A Topic (mesh)

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Early Termination Of Clinical Trials (mesh)

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Preterm, Low Birth Weight And Health Of The Newborn

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Perinatal Period - Conditions Originating In Perinatal Period

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Drug-Related Side Effects And Adverse Reactions

# publications[].label
Similarities, reliability and gaps in assessing the quality of conduct of systematic reviews using AMSTAR-2 and ROBIS: systematic survey of nutrition reviews.

# publications[].label
Effect of standardized training on the reliability of the Cochrane risk of bias assessment tool: a prospective study.

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Reporting of IMMPACT-recommended core outcome domains among trials assessing opioids for chronic non-cancer pain.

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Limited responsiveness related to the minimal important difference of patient-reported outcomes in rare diseases.

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Opioids for chronic non-cancer pain: a protocol for a systematic review of randomized controlled trials.

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Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study).

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Microbiota signatures and mucosal healing in the use of enteral nutrition therapy v. corticosteroids for the treatment of children with Crohn's disease: a systematic review and meta-analysis.

# publications[].label
Prevention of Clostridium difficile Infection: A Systematic Survey of Clinical Practice Guidelines.

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Patterns of Red and Processed Meat Consumption and Risk for Cardiometabolic and Cancer Outcomes: A Systematic Review and Meta-analysis of Cohort Studies.

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Optimizing practice guidelines through incorporating patient and family values and preferences.

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Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid.

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Nutrition users' guides: systematic reviews part 1 -structured guide for methodological assessment, interpretation and application of systematic reviews and meta-analyses of non-randomised nutritional epidemiology studies.

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Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children.

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Impact of sodium intake on blood pressure, mortality and major cardiovascular events: an umbrella review of systematic reviews and meta-analyses.

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Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.

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Causal inference, interpreting and communicating results on red and processed meat.

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Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis.

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1016  Probiotics for the Prevention of Pediatric Antibioticassociated Diarrhea

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Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature.

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Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study.

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Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in extremely preterm infants: a clinical practice guideline incorporating family values and preferences.

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Systematic review: effect of probiotics on antibiotic-induced microbiomedisruption.

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Measurement of Treatment Effects Requires Instruments Responsive to Change Based on the Minimal Important Difference.

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Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review.

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Mo1924 - Probiotics for the Prevention of Clostridium-Difficile Associated Diarrhea in Adults and Children

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Water and sanitation infrastructure for health: The impact of foreign aid.

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The use of expertise-based randomized controlled trials to assess spinal manipulation and acupuncture for low back pain: a systematic review.

# publications[].label
Influence of unhealthy food and beverage marketing on children's dietary intake and preference: a systematic review and meta-analysis of randomized trials.

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Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis.

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Serious reporting deficiencies exist in minimal important difference studies: current state and suggestions for improvement.

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People's Values and Preferences about Meat Consumption in View of the Potential Environmental Impacts of Meat: A Mixed-methods Systematic Review.

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Poor quality patient reported outcome measures bias effect estimates in orthopaedic randomized studies.

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Combining follow-up and change data is valid in meta-analyses of continuous outcomes: a meta-epidemiological study.

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Comparative effectiveness of single foods and food groups on body weight: a systematic review and network meta-analysis of 152 randomized controlled trials.

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Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data.

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Effect of Lower Versus Higher Red Meat Intake on Cardiometabolic and Cancer Outcomes: A Systematic Review of Randomized Trials.

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Early and frequent exposure to antibiotics in children and the risk of obesity: systematic review and meta-analysis of observational studies.

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Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics.

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Predictors of higher quality of systematic reviews on nutrition in cancer prevention

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GRADE guidelines 17: assessing the risk of bias associated with missing participant outcome data in a body of evidence.

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MNT Evidence Update: Comparative Effectiveness of Dietary Programs for Reducing Mortality and Cardiovascular Events in Adults with Increased Cardiovascular Risk.

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Probiotics for pediatric antibiotic-associated diarrhea: a meta-analysis of randomized placebo-controlled trials.

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Conceptual framework for health-related quality of life assessment in acute gastroenteritis.

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Probiotics for the prevention of antibiotic-associated adverse events in children  a systematic review to inform development of a core outcome set

# publications[].label
Prevalence, characteristics, and publication of discontinued randomized trials.

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Virtual reality simulation training in endoscopy: a Cochrane review and meta-analysis.

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Recent advances in patient and proxy-reported quality of life research.

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Evaluating adults health-related values and preferences about unprocessed red meat and processed meat consumption: protocol for a cross-sectional mixed-methods study

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The Scientific Basis of Guideline Recommendations on Sugar Intake.

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CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration.

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Credibility of claims of subgroup effects in randomised controlled trials: systematic review.

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Probiotics and the Prevention of Antibiotic-Associated Diarrhea in Infants and Children.

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Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium.

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The Philosophy of Evidence-Based Principles and Practice in Nutrition.

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Probiotics for the prevention of Clostridioides difficile-associated diarrhea in adults and children.

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Dietary interventions for multiple sclerosis-related outcomes: Summary of a cochrane review.

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N-acetylcysteine use among patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized trials.

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The Quick Mild Cognitive Impairment screen correlated with the Standardized Alzheimer's Disease Assessment Scale-cognitive section in clinical trials.

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Safety and tolerability of North American ginseng extract in the treatment of pediatric upper respiratory tract infection: a phase II randomized, controlled trial of 2 dosing schedules.

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Causal language use in systematic reviews of observational studies is often inconsistent with intent: a systematic survey.

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Nutrition Users Guides: an introduction to structured guides to evaluate the nutrition literature

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Erratum to GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profilescontinuous outcomes [J Clin Epidemiol 2013;66(2):173-183]

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Patient-reported outcomes in meta-analyses-part 2: methods for improving interpretability for decision-makers.

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Non-communicable disease risk associated with red and processed meat consumption-magnitude, certainty, and contextuality of risk?

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Pooling health-related quality of life outcomes in meta-analysis-a tutorial and review of methods for enhancing interpretability.

# publications[].label
Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.

# publications[].label
The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review.

# publications[].label
Probiotics for the prevention of Clostridium difficile-associated diarrhea: a systematic review and meta-analysis.

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Minimally important difference estimates and methods: a protocol.

# publications[].label
Saturated fat and human health: a protocol for a methodologically innovative systematic review and meta-analysis to inform public health nutrition guidelines.

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Herbal medications for anxiety, depression, pain, nausea and vomiting related to preoperative surgical patients: a systematic review and meta-analysis of randomised controlled trials.

# publications[].label
Microbial Preparations (Probiotics) for the Prevention of Clostridium difficile Infection in Adults and Children: An Individual Patient Data Meta-analysis of 6,851 Participants.

# publications[].label
Nutrition users' guides: RCTs part 1 - structured guide for assessing risk of bias in randomised controlled trials that address therapy or prevention questions.

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Evidence-Based Practice Competencies among Nutrition Professionals and Students: A Systematic Review

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Probiotics for the prevention of pediatric antibiotic-associated diarrhea.

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Health-Related Values and Preferences Regarding Meat Consumption: A Mixed-Methods Systematic Review.

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Red and Processed Meat Consumption and Risk for All-Cause Mortality and Cardiometabolic Outcomes.

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Incorporation of patient and family values and preferences for health-related outcomes in paediatric obesity management: A systematic review.

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Presentation approaches for enhancing interpretability of patient-reported outcomes (PROs) in meta-analysis: a protocol for a systematic survey of Cochrane reviews.

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Understanding effect size: an international online survey among psychiatrists, psychologists, physicians from other medical specialities, dentists and other health professionals.

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Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials.

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Authors seldom report the most patient-important outcomes andabsoluteeffect measures in systematic review abstracts.

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Minimally Important Differences in Patient or Proxy-Reported Outcome Studies Relevant to Children: A Systematic Review.

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Low and very low carbohydrate diets for diabetes remission.

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Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.

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Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses.

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Handling trial participants with missing outcome data when conducting a meta-analysis: a systematic survey of proposed approaches.

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Using decision thresholds for ranking treatments in network meta-analysis results in more informative rankings.

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CONSORT extension for reporting N-of-1 trials (CENT) 2015: Explanation and elaboration.

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Are neonatal clinical practice guidelines truly evidence-based? A case for incorporating family values and preferences.

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LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact.

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Evidence-Based Practice Competencies among Nutrition Professionals and Students: A Systematic Review.

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Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children.

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PATIENT-REPORTED OUTCOMES IN RARE LYSOSOMAL STORAGE DISEASES: KEY INFORMANT INTERVIEWS AND A SYSTEMATIC REVIEW PROTOCOL.

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Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.

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Evidence Collection and Evaluation for the Development of Dietary Guidelines and Public Policy on Nutrition.

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Evaluation of Health-Related Values and Preferences of Adults Who Were Preterm Infants and Parents of Preterm Infants Concerning Use of Prophylactic Cyclooxygenase Inhibitor Drugs.

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Health Related Values and Preferences Regarding Meat Intake: A Cross-Sectional Mixed-Methods Study.

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Food-based dietary guidelines in Spain: an assessment of their methodological quality.

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Standard 5: selection, measurement, and reporting of outcomes in clinical trials in children.

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New methods can extend the use of minimal important difference units in meta-analyses of continuous outcome measures.

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Measurement issues in trials of pediatric acute diarrheal diseases: a systematic review.

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Methods fortrustworthy nutritional recommendations NutriRECS (Nutritional Recommendations and accessible Evidence summaries Composed of Systematic reviews): a protocol.

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Visual Analogue Scale has higher assay sensitivity than WOMAC pain in detecting between-group differences in treatment effects: a meta-epidemiological study.

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Evaluating the credibility of anchor based estimates of minimal important differences for patient reported outcomes: instrument development and reliability study.

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Addressing continuous data measured with different instruments for participants excluded from trial analysis: a guide for systematic reviewers.

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Human and Bovine Colostrum for Prevention of Necrotizing Enterocolitis: A Meta-analysis.

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A randomized controlled trial of amitriptyline versus gabapentin for complex regional pain syndrome type I and neuropathic pain in children.

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A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol.

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Safety and Efficacy of the Combination of Propofol and Ketamine for Procedural Sedation/Anesthesia in the Pediatric Population: A Systematic Review and Meta-analysis.

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Probiotics for the prevention of Clostridium difficile-associated diarrhea. In response.

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GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes.

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Probiotics and synbiotics for the prevention of postoperative infections following abdominal surgery: a systematic review and meta-analysis of randomized controlled trials.

# publications[].label
Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis.

# publications[].label
Reduction of Red and Processed Meat Intake and Cancer Mortality and Incidence: A Systematic Review and Meta-analysis of Cohort Studies.

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Unprocessed Red Meat and Processed Meat Consumption.

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Comparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis.

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Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers.

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Methods to convert continuous outcomes into odds ratios of treatment response and numbers needed to treat: meta-epidemiological study.

# publications[].label
Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study.

# publications[].label
Effectiveness of pharmacological interventions for managing obesity in children and adolescents: A systematic review and meta-analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline.

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Reporting missing participant data in randomised trials: systematic survey of the methodological literature and a proposed guide.

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Saturated fat, the estimated absolute risk and certainty of risk for mortality and major cancer and cardiometabolic outcomes: an overview of systematic reviews.

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Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial.

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Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units.

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Prophylactic cyclooxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network metaanalysis

# publications[].label
Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers.

# publications[].label
Although not consistently superior, the absolute approach to framing the minimally important difference has advantages over the relative approach.

# publications[].label
Patient-reported outcomes in meta-analyses--Part 1: assessing risk of bias and combining outcomes.

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Antibiotic-perturbed microbiota and the role of probiotics.

# publications[].label
Diverse criteria and methods are used to compare treatment effect estimates: a scoping review.

# publications[].label
Ketamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials.

# publications[].label
Minimal important difference estimates for patient-reported outcomes: A systematic survey.

# publications[].label
Red and Processed Meat Consumption and Risk for All-Cause Mortality and Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Cohort Studies.

# publications[].label
Meta-analyses of safety data: a comparison of exact versus asymptotic methods.

# publications[].label
Nutrition Users' Guides: RCTs Part 2 - structured guide for interpreting and applying study results from randomised controlled trials on therapy or prevention questions.

# publications[].label
Optimal Strategies for Reporting Pain in Clinical Trials and Systematic Reviews: Recommendations from an OMERACT 12 Workshop.

# publications[].label
Do clinicians understand the size of treatment effects? A randomized survey across 8 countries.

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Adverse events associated with pediatric spinal manipulation: a systematic review.

# publications[].label
Reconciling contrasting guideline recommendations on red and processed meat for health outcomes.

# publications[].label
Erratum to: A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol

# publications[].label
Dexamethasone as an adjuvant to peripheral nerve block

# publications[].label
The Scientific Basis of Guideline Recommendations on Sugar Intake: A Systematic Review.

# publications[].label
Evaluating adults' health-related values and preferences about unprocessed red meat and processed meat consumption: protocol for a cross-sectional mixed-methods study.

# publications[].label
Probiotics for the prevention of pediatric antibiotic-associated diarrhea.

# publications[].label
A survey of stakeholders' perceived importance of health indicators and subgroup analyses to inform the Canadian clinical practice guideline for managing paediatric obesity.

# publications[].label
Effect of standardized training on the reliability of the Cochrane risk of bias assessment tool: a study protocol.

# publications[].label
Reporting, handling and assessing the risk of bias associated with missing participant data in systematic reviews: a methodological survey.

# publications[].label
Probiotics for the prevention of pediatric antibiotic-associated diarrhea.

# publications[].label
Values and Preferences Related to Cancer Risk among Red and Processed Meat Eaters: A Pilot Cross-Sectional Study with Semi-Structured Interviews.

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Methods for the Selection of Covariates in Nutritional Epidemiology Studies: A Meta-Epidemiological Review.

# publications[].label
Effectiveness of surgical interventions for managing obesity in children and adolescents: A systematic review and meta-analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline.

# publications[].label
Values and preferences influencing willingness to change red and processed meat consumption in response to evidence-based information: a mixed methods study.

# publications[].label
Biofeedback for treatment of irritable bowel syndrome.

# publications[].label
Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials.

# publications[].label
Probiotics for the prevention of antibiotic-associated adverse events in children-A scoping review to inform development of a core outcome set.

# publications[].label
Challenges in applying the GRADE approach in public health guidelines and systematic reviews: a concept article from the GRADE Public Health Group.

# publications[].label
Are systematic reviews addressing nutrition for cancer prevention trustworthy? A systematic survey of quality and risk of bias.

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Microbial Preparations (Probiotics) for the Prevention of Clostridium difficile Infection in Adults and Children: An Individual Patient Data Meta-analysis of 6,851 Participants - CORRIGENDUM.

# researcherOn[].label
Evidence-based Nutrition Education and Research Guidance

# researcherOn[].awardedBy.label
National Institute of Diabetes and Digestive and Kidney Diseases - (Bethesda, Maryland, United States)

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Cross-Disciplinary Training in Evidence-Based Health Care for Applied Health Science Faculty

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Texas A&M University System - (College Station, Texas, United States)

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Unintended Consequences of Participating in Pediatric Obesity Interventions

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Canadian Institute of Child Health - (Ottawa, Ontario, Canada)

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Enhancing Critical Thinking and Appraisal Skills with Undergraduate Nutrition Students

# researcherOn[].awardedBy.label
Texas A&M University System - (College Station, Texas, United States)

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Disseminating Clinical Practice Guidelines for Managing Pediatric Obesity to Health Care Providers

# researcherOn[].awardedBy.label
Canadian Institute of Child Health - (Ottawa, Ontario, Canada)

# organizations[]
College of Agriculture and Life Sciences

# schools[]
College of Agriculture and Life Sciences

# inTheNews[].label
Evidence-based nutrition practice focus of half-day online workshops