# positions[].organizations[].label
Institute of Genome Sciences and Society

# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# overview
Our laboratory uses the mouse as an experimental genetic model to investigate factors that contribute to inter-individual differences in health and disease. Ourcurrent research activities include the identification and functional characterization of alleles contributing to cancer susceptibility, the function of theErbbgenefamily in development and disease, and the role of genetic variation in response to environmental stimuli. To support these investigations, we also aredeveloping new genetic tools to support mammalian systems genetic approaches to phenotypes with complex genetic and environmental etiologies.

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
2.6 Resources And Infrastructure (aetiology)

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
Platelet Endothelial Cell Adhesion Molecule-1

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Clinical Trials And Supportive Activities

# keywords[]
Receptor, Transforming Growth Factor-beta Type I

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
Mechanistic Target Of Rapamycin Complex 2

# keywords[]
3102 Bioinformatics And Computational Biology

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Von Hippel-Lindau Tumor Suppressor Protein

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
3 Prevention Of Disease And Conditions, And Promotion Of Well-being

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Von Hippel-Lindau Tumor Suppressor Protein

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
Intracellular Signaling Peptides And Proteins

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Drug-Related Side Effects And Adverse Reactions

# keywords[]
Clustered Regularly Interspaced Short Palindromic Repeats

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
Intercellular Signaling Peptides And Proteins

# keywords[]
Theiler's Murine Encephalomyelitis Virus, (tmev)

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
2.2 Factors Relating To The Physical Environment

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Glp-2 (3-33), Glucagon-like Peptide 2 Antagonist

# keywords[]
Pcna, Proliferating Cell Nuclear Antigen

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Case Western Reserve University - (Cleveland, Ohio, United States)

# awardsAndHonors[].label
Individual National Research Service Award

# publications[].label
Progression of epidermal growth factor receptor (EGFR)-independent colorectal cancer

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research

# publications[].label
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor

# publications[].label
Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice

# publications[].label
Estrogen Protects Cardiac Function and Energy Metabolism in Dilated Cardiomyopathy Induced by Loss of Cardiac IRS1 and IRS2.

# publications[].label
Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice

# publications[].label
Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts

# publications[].label
Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel.

# publications[].label
Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice.

# publications[].label
Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment.

# publications[].label
Genetic analysis of hematological parameters in incipient lines of the collaborative cross.

# publications[].label
Sex and Diet Specific Differences In Bone Mass of 4 Mouse Strains: Can Mice Tell Us What to Eat for Bone Health?

# publications[].label
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.

# publications[].label
Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles.

# publications[].label
Differential expression of the full-length and truncated forms of the epidermal growth factor receptor in the preimplantation mouse uterus and blastocyst.

# publications[].label
Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.

# publications[].label
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Development of a systems genetics platform using the Collaborative Cross for diseases and therapies with complex etiologies

# publications[].label
Identification of MAGI-3 as a transforming growth factor- tail binding protein

# publications[].label
Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows

# publications[].label
The genome architecture of the collaborative cross mouse genetic reference population

# publications[].label
Gestational binge alcohol-induced alterations in maternal uterine artery transcriptome.

# publications[].label
Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms (vol 71, pg 1, 2001)

# publications[].label
Genetic support for a critical role EGF receptor signaling in intestinal neoplasia in ApcMin mice

# publications[].label
Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross.

# publications[].label
Case Report: Paucisymptomatic College-Age Population as a Reservoir for Potentially Neutralization-Resistant Severe Acute Respiratory Syndrome Coronavirus 2 Variants.

# publications[].publisher
American Society of Tropical Medicine and Hygiene

# publications[].label
Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.

# publications[].label
Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice.

# publications[].label
Modeling the cancer patient with genetically engineered mice: prediction of toxicity from molecule-targeted therapies.

# publications[].label
Assessment of genetic modifiers for phenotypic severity of beta ENaC transgenic mice

# publications[].label
Somatic cell mapping of bovine clathrin light chain genes: identification of a new bovine syntenic group.

# publications[].label
Animal models of autism spectrum disorders: information for neurotoxicologists.

# publications[].label
Diallel analysis reveals Mx1-dependent and Mx1-independent effects on response to influenza A virus in mice

# publications[].label
Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation

# publications[].label
PKC tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

# publications[].label
Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK

# publications[].label
Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice.

# publications[].label
Quantitative comparison of protocols for DNA attachment and hybridization to glass

# publications[].label
The collaborative cross: a recombinant inbred mouse population for the systems genetic era.

# publications[].label
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors

# publications[].label
Molecular and genetic analysis of a carcinogen-based mouse model for hepatocarcinogenesis

# publications[].label
Developing gene drive technologies to eradicate invasive rodents from islands

# publications[].label
Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo

# publications[].label
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice.

# publications[].label
Synteny mapping of human chromosome 8 loci in cattle.

# publications[].label
Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains

# publications[].label
Fat Mass Gained Prior to Dietary Intervention Predicts Efficacy of Personalized Dietary Guidance in Mice

# publications[].label
Tyrosine phosphorylation of protein kinase C delta during calcium-induced keratinocyte differentiation involves activation of epidermal growth factor receptor.

# publications[].label
Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse.

# publications[].label
Genomic mapping within the albino-deletion complex using individual early postimplantation mouse embryos.

# publications[].label
Somatic cell mapping and restriction fragment length polymorphism analysis of bovine insulin-like growth factor I.

# publications[].label
Status and access to the Collaborative Cross population.

# publications[].label
Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling.

# publications[].label
Bayesian hierarchical modeling for time course microarray experiments.

# publications[].label
Metastatic potential as a heritable trait

# publications[].label
Synteny mapping in the bovine: genes from human chromosome 4.

# publications[].label
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype.

# publications[].label
The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: Implications for QTL discovery and systems genetics

# publications[].label
Down's syndrome: Paradox of a tumour repressor

# publications[].label
Development of novel, non-toxic rifamycins that reverse drug resistance

# publications[].label
Elucidating the Functional Consequences of the Trichloroethylene Associated Von-Hippel Lindau Tumor Suppressor Gene Mutation Using a Genetically Engineered Model System

# publications[].label
Host genetic background influences diverse neurological responses to viral infection in mice.

# publications[].label
Abstract 819: ERBB4 mediates IL10-induced growth of EGFR-independent colon tumors

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Genetic characterization of invasive house mouse populations on small islands

# publications[].label
Tissue Level Diet and Sex-by-Diet Interactions Reveal Unique Metabolite and Clustering Profiles Using Untargeted Liquid Chromatography-Mass Spectrometry on Adipose, Skeletal Muscle, and Liver Tissue in C57BL6/J Mice.

# publications[].label
Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response

# publications[].label
Parent-of-origin effects on cardiac response to pressure overload in mice

# publications[].label
Quantitative trait locus analysis of tumor morphology in a mouse model of human colorectal cancer

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer.

# publications[].label
Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice.

# publications[].label
TreeQA: quantitative genome wide association mapping using local perfect phylogeny trees.

# publications[].label
Differential expression of the full-length and truncated forms of the epidermal growth factor receptor in the preimplantation mouse uterus and blastocyst.

# publications[].label
The nature and identification of quantitative trait loci: A community's view

# publications[].label
Status and access to the Collaborative Cross population

# publications[].label
Targeted inactivation of EGF receptor inhibits renal collecting duct development and function

# publications[].label
Xenobiotic metabolism in a mouse model of non-alcoholic fatty liver disease: A case study of the ubiquitous environmental contaminant tetrachloroethylene

# publications[].label
Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse.

# publications[].label
The epidermal growth factor receptor critically regulates endometrial function during early pregnancy.

# publications[].label
Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice.

# publications[].label
Sex-specific genetic architecture in response to American and ketogenic diets.

# publications[].label
Stromal Cell and Colonocyte EGFR Are Required for Efficient Tumor Xenograft Growth of Colon Cancer Cells

# publications[].label
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

# publications[].label
Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles

# publications[].label
Masking in waved-2 mice: EGF receptor control of locomotion questioned.

# publications[].label
Epidermal ADAM17 maintains the skin barrier by regulating EGFR liganddependent terminal keratinocyte differentiation

# publications[].label
Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned.

# publications[].label
Identifying genetic modifiers of PTEN using the Collaborative Cross mouse panel

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Erratum: Microarray foray (Breast Cancer Research (2000) vol. 2 (8-9))

# publications[].label
Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes.

# publications[].label
Genotype x diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis

# publications[].label
gQTL: A Web Application for QTL Analysis Using the Collaborative Cross Mouse Genetic Reference Population.

# publications[].label
Epithelial-specific ERBB3 deletion results in a genetic background-dependent increase in intestinal and colon polyps that is mediated by EGFR.

# publications[].label
Characterization of a set of variable number of tandem repeat markers conserved in bovidae.

# publications[].label
Modeling cancer patient populations in mice: complex genetic and environmental factors.

# publications[].label
Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice.

# publications[].label
Peanut butter as an alternative dose delivery method to prevent strain-dependent orogastric gavage-induced stress in mouse teratogenicity studies.

# publications[].label
Syntenic conservation between humans and cattle. II. Human chromosome 12.

# publications[].label
Genetic modifiers prevent left ventricular hypertrophy in the Epidermal Growth Factor Receptor (Egfr/ErbB1) waved-2 mouse model for aortic stenosis

# publications[].label
The EGFR is required for proper innervation to the skin.

# publications[].label
Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors.

# publications[].label
MicroRNA expression in the livers of inbred mice.

# publications[].label
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

# publications[].label
Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain

# publications[].label
Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross.

# publications[].label
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.

# publications[].label
ERBBs in the gastrointestinal tract: recent progress and new perspectives.

# publications[].label
Allele insertion mutagenesis at the EP3 receptor locus

# publications[].label
Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

# publications[].label
Toxicogenetics: Population-based testing of drug and chemical safety in mouse models

# publications[].label
A New Polygenic Model for Nonfamilial Colorectal Cancer Inheritance Based on the Genetic Architecture of the Azoxymethane-Induced Mouse Model.

# publications[].label
Modeling cancer patient populations in mice: complex genetic and environmental factors.

# publications[].label
Genetic analysis of complex traits in the emerging Collaborative Cross.

# publications[].label
Cardiac response to pressure-induced hypertrophy is genetic background dependent

# publications[].label
Population Variability and the Teratogenic Effects of Exposure to 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during Pregnancy.

# publications[].label
Modeling Host Genetic Regulation of Influenza Pathogenesis in the Collaborative Cross

# publications[].label
Demonstrating the Critical Role of Uterine Erbb Signaling in Fertility

# publications[].label
Architecture of energy balance traits in emerging lines of the Collaborative Cross.

# publications[].label
Mapping of bovine cytokeratin sequences to four different sites on three chromosomes.

# publications[].label
Abstract PL03-01: A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.

# publications[].label
Progression of colorectal cancer through epidermal growth factor receptor (EGFR)-independent mechanisms

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Impact of E-cig aerosol vaping on fetal and neonatal respiratory development and function.

# publications[].label
Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

# publications[].label
Systemic review of genetic and epigenetic factors underlying differential toxicity to environmental lead (Pb) exposure.

# publications[].label
Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice.

# publications[].label
Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary

# publications[].label
Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor

# publications[].label
Locally Fixed Alleles: A method to localize gene drive to island populations

# publications[].label
Gene, Sex and Diet Interact to Control the Tissue Metabolome

# publications[].label
Viral Clearance and Neuroinflammation in Acute TMEV Infection Vary by Host Genetic Background.

# publications[].label
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.

# publications[].label
A SYSTEMATIC EVALUATION OF AN F2 MOUSE CROSS PREDISPOSED TO OBESITY AND MAMMARY TUMOR DEVELOPMENT AND FED VARYING LEVELS OF DIETARY FAT

# publications[].label
Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis.

# publications[].label
SYNTENIC ASSIGNMENT OF HSA-9 AND HSA-12 HOMOLOGS IN THE BOVINE - PRELIMINARY EVIDENCE FOR THE ROLE OF FRAGILE SITES IN MAMMALIAN GENOME EVOLUTION

# publications[].label
Identification of a novel polymorphism in X-linked sterol-4-alpha-carboxylate 3-dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in I/LnJ mice.

# publications[].label
Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes.

# publications[].label
The Collaborative Cross at Oak Ridge National Laboratory: Developing a powerful resource for systems genetics

# publications[].label
Syntenic conservation between humans and cattle. I. Human chromosome 9.

# publications[].label
Regional localization of mouse Abl and Mos proto-oncogenes by in situ hybridization.

# publications[].label
The gastrointestinal microbiome: a malleable, third genome of mammals.

# publications[].label
Genetic background influences survival of infections with Salmonella enterica serovar Typhimurium in the Collaborative Cross.

# publications[].label
SYSGENET: a meeting report from a new European network for systems genetics.

# publications[].label
Genetic dissection of complex and quantitative traits: From fantasy to reality via a community effort

# publications[].label
Replication and narrowing of gene expression quantitative trait loci using inbred mice.

# publications[].label
Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations.

# publications[].label
Animal models of autism spectrum disorders: Information for neurotoxicologists

# publications[].label
SSLPs to map genetic differences between the 129 inbred strains and closed-colony, random-bred CD-1 mice.

# publications[].label
The Collaborative Cross, a community resource for the genetic analysis of complex traits.

# publications[].label
Identification of a novel polymorphism in X-linked sterol-4-alpha-carboxylate 3-dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in i/LnJ mice

# publications[].label
A Whole Genome Assembly of the Horn Fly, Haematobia irritans, and Prediction of Genes with Roles in Metabolism and Sex Determination.

# publications[].label
Quantitative trait locus analysis using recombinant inbred intercrosses: Theoretical and empirical considerations

# publications[].label
Genome-level analysis of genetic regulation of liver gene expression networks.

# publications[].label
Localization of the murine methylmalonyl CoA mutase (Mut) locus on chromosome 17 by in situ hybridization.

# publications[].label
Genetic background-dependent effects of diet on health and production traits.

# publications[].label
Genetic analysis of hematological parameters in incipient lines of the collaborative cross

# publications[].label
Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism.

# publications[].label
Genetic and immunological contributors to virus-induced paralysis.

# publications[].label
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.

# publications[].label
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.

# publications[].label
Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene.

# publications[].label
Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes.

# publications[].label
SYNTENIC MAPPING OF 37 LOCI IN CATTLE - CHROMOSOMAL CONSERVATION WITH MOUSE AND MAN

# publications[].label
Genetic analysis of complex traits in the emerging Collaborative Cross

# publications[].label
Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel

# publications[].label
Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes

# publications[].label
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

# publications[].label
Stromal Cell EGFR Enhances Colon Cancer Cell Growth in Tumor Xenografts

# publications[].label
The untapped potential of genetically engineered mouse models in chemoprevention research: opportunities and challenges.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor.

# publications[].label
Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15

# publications[].label
Essential role of the EGF network in LH-induced ovulation

# publications[].label
Activation of Putative Compensatory Pathways upon Deletion of Erbb3 in Mutant EGFR-driven Lung Cancer

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

# publications[].label
Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctions.

# publications[].label
Parent-of-origin effects on cardiac response to pressure overload in mice.

# publications[].label
Elucidating Mechanisms of Tolerance to Salmonella Typhimurium Across Long-Term Infections Using the Collaborative Cross

# publications[].label
Constitutive WNT Signaling via CTNNB1 Stabilization in the Yolk Sac Epithelium Results in Embryonic Lethality in Mice

# publications[].label
Dietary fat alters body composition, mammary development, and cytochrome P450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive Aryl hydrocarbon receptors

# publications[].label
Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice

# publications[].label
Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage.

# publications[].label
Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene

# publications[].label
Demonstrating the Critical Role of Uterine Erbb Signaling in Fertility.

# publications[].label
Conditional inactivation of TNF-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones.

# publications[].label
Pharmaceutical and genetic reduction of epidermal growth factor receptor (EGFR/ERBB) signaling impairs cardiac function

# publications[].label
Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials.

# publications[].label
Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome.

# publications[].label
Human epithelial-specific response to pathogenic Campylobacter jejuni

# publications[].label
Gut microbiota and host genetics modulate the effect of diverse diet patterns on metabolic health.

# publications[].label
Borrelia and Other Zoonotic Pathogens in Ixodes ricinus and Dermacentor reticulatus Ticks Collected from the Chernobyl Exclusion Zone on the 30th Anniversary of the Nuclear Disaster.

# publications[].label
Chronic exposure to e-cig aerosols during early development causes vascular dysfunction and offspring growth deficits.

# publications[].label
Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms.

# publications[].label
Expression quantitative trait loci for extreme host response to influenza A in pre-collaborative cross mice

# publications[].label
The next generation of rodent eradications: Innovative technologies and tools to improve species specificity and increase their feasibility on islands

# publications[].label
The untapped potential of genetically engineered mouse models in chemoprevention research: Opportunities and challenges

# publications[].label
Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3.

# publications[].label
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.

# publications[].label
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice

# publications[].label
Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice.

# publications[].label
Extensive sex-specific and regional variations observed in the microbiome of Dermacentor reticulatus.

# publications[].label
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis (vol 17, pg 1242, 2011)

# publications[].label
Syntenic assignment of human chromosome 1 homologous loci in the bovine.

# publications[].label
Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage

# publications[].label
Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.

# publications[].label
Genetic background influences survival of infections with Salmonella enterica serovar Typhimurium in the Collaborative Cross

# publications[].label
TREEQA: QUANTITATIVE GENOME WIDE ASSOCIATION MAPPING USING LOCAL PERFECT PHYLOGENY TREES

# publications[].label
Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice.

# publications[].label
Targeted disruption of EGFR impairs keratinocyte responses to the v-ras(Ha) oncogene in vitro and in vivo.

# publications[].label
Genetic dissection of mechanisms underlying epidermal growth factor receptor-independent colorectal cancer development

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Investigating gene function using mouse models.

# publications[].label
Bayesian hierarchical modeling for time course microarray experiments

# publications[].label
Status and access to the Collaborative Cross population (vol 23, pg 706, 2012)

# publications[].label
Meeting report for the 4th Annual Complex Trait Consortium Meeting: From QTLs to Systems Genetics

# publications[].label
Development of a quantitative, high throughput placental defect screen

# publications[].label
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: effects of dose, route, and diet.

# publications[].label
ERBBs in the gastrointestinal tract: Recent progress and new perspectives

# publications[].label
Abstract 410: Development of novel, non-toxic rifamycins that reverse drug resistance

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice.

# publications[].label
Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia.

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Derivation of stable embryonic stem cell-like, but transcriptionally heterogenous, induced pluripotent stem cells from non-permissive mouse strains.

# publications[].label
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype

# publications[].label
Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice.

# publications[].label
R2d2 Drives Selfish Sweeps in the House Mouse.

# publications[].label
Prevention of tumorigenesis in mice by exercise is dependent on strain background and timing relative to carcinogen exposure.

# publications[].label
Meeting report for the 4th annual Complex Trait Consortium meeting: from QTLs to systems genetics.

# publications[].label
Baseline Gait and Motor Function Predict Long-Term Severity of Neurological Outcomes of Viral Infection.

# publications[].label
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand- dependent terminal keratinocyte differentiation

# publications[].publisher
PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO.

# publications[].label
In vivo characterization of the role of Erbb3 in mutant EGFR-induced lung tumorigenesis

# publications[].label
Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis.

# publications[].label
Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis.

# publications[].label
MicroRNA expression in the livers of inbred mice

# publications[].label
Population structure and inbreeding in wild house mice (Mus musculus) at different geographic scales

# publications[].label
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation (vol 209, pg 1105, 2012)

# publications[].label
Replication and narrowing of gene expression quantitative trait loci using inbred mice

# publications[].label
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.

# publications[].label
Cross-talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification.

# publications[].label
Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain

# publications[].label
Staphylococcus epidermidis MSCRAMM SesJ Is Encoded in Composite Islands.

# publications[].label
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

# publications[].label
Genetic and pharmaceutical reduction of epidermal growth factor receptor (egfr/erbb1) signaling results in valvular and arterial calcification

# publications[].label
Overexpression of IGF-1 During Early Development Expands the Number of Mammary Stem Cells and Primes them for Transformation.

# publications[].label
Genetic support for a critical role EGF receptor signaling in intestinal neoplasia in ApcMin mice

# publications[].label
Quantitative PCR assays for mouse enteric flora reveal strain-dependent differences in composition that are influenced by the microenvironment

# publications[].label
Epidermal growth factor receptor null placentae consist of trophoblasts with aberrant cell cycles

# publications[].label
Epidermal EGFR signaling controls leukocyte infiltration in the skin and prevents systemic disease

# publications[].label
Host genetics and gut microbiota cooperatively contribute to azoxymethane-induced acute toxicity in Collaborative Cross mice.

# publications[].label
Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15.

# publications[].label
The EGFR is required for proper innervation to the skin

# publications[].label
EGFR signaling promotes TGF-dependent renal fibrosis.

# publications[].label
Genotype Sequence Segmentation: Handling Constraints and Noise

# publications[].label
Resilience in Long-Term Viral Infection: Genetic Determinants and Interactions.

# publications[].label
Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts.

# publications[].label
The nature and identification of quantitative trait loci: a community's view.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials.

# publications[].label
Stromal Cell and Colonocyte EGFR Are Required for Efficient Tumor Xenograft Growth of Colon Cancer Cells

# publications[].label
Corrigendum: analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance.

# publications[].label
Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary.

# publications[].label
Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression

# publications[].label
Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Bayesian multiple quantitative trait loci mapping for complex traits using markers of the entire genome

# publications[].label
Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response.

# publications[].label
Conditional inactivation of TNF-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones.

# publications[].label
Leveraging a natural murine meiotic drive to suppress invasive populations

# publications[].label
ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Metastatic potential as a heritable trait.

# publications[].label
The genome architecture of the Collaborative Cross mouse genetic reference population.

# publications[].label
Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression.

# publications[].label
Late-life dietary folate restriction reduces biosynthetic processes without compromising healthspan in mice.

# publications[].label
Hepatocyte ERBB3 and EGFR are required for maximal CCl4-induced liver fibrosis.

# publications[].label
Somatic cell mapping, polymorphism, and linkage analysis of bovine prolactin-related proteins and placental lactogen.

# publications[].label
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function.

# publications[].label
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: Temporal- and background-dependent development of concentric left ventricular hypertrophy

# publications[].label
Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: Roles of transforming growth factor- and PTGS2

# publications[].label
Analysis of strain, sex, and diet-dependent modulation of gut microbiota reveals candidate keystone organisms driving microbial diversity in response to American and ketogenic diets.

# publications[].label
Efficient Data-Mining Methods Enabling Genome-Wide Computing

# publications[].label
The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics.

# publications[].label
R2d2 drives selfish sweeps in the house mouse

# publications[].label
Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis

# publications[].label
A Ketogenic Diet In Mice Reduces Cardiac Protein Synthesis Compared to a Western Diet

# publications[].label
Genomic analysis of the major bovine milk protein genes.

# publications[].label
Role of von-Hippel Lindau Tumor Suppressor Gene Mutations in the Modulation of Susceptibility to Environmental Carcinogens

# publications[].label
EGFR signaling promotes TGF-dependent renal fibrosis

# publications[].label
Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2

# publications[].label
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.

# publications[].label
Sexual Dimorphism in Control of Heart Failure in Insulin Resistance

# publications[].label
Investigating Tissue Level Gene-by-diet Interactions with Metabolomics

# publications[].label
Genetic mapping of a Ptch1-associated rhabdomyosarcoma susceptibility locus on mouse chromosome 2.

# publications[].label
Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain.

# publications[].label
Adding robustness to rigor and reproducibility for the three Rs of improving translational medical research.

# publications[].publisher
American Society for Clinical Investigation

# publications[].label
Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta.

# publications[].label
Human epithelial-specific response to pathogenic Campylobacter jejuni.

# publications[].label
Genetic and metabolic links between the murine microbiome and memory.

# publications[].label
ERBB4 mediates IL10-induced growth of EGFR-independent colon tumors

# publications[].label
Toxicogenetics: population-based testing of drug and chemical safety in mouse models.

# publications[].label
Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research.

# publications[].label
Characterization of the invasive and inflammatory traits of oral Campylobacter rectus in a murine model of fetoplacental growth restriction and in trophoblast cultures.

# publications[].label
189 EGFR Is Required for Tumor Promotion By Dietary Fat in a Murine Model of Inflammation-Associated Colon Cancer

# publications[].label
Prophylactic vaccination targeting ERBB3 decreases polyp burden in a mouse model of human colorectal cancer.

# publications[].label
Antecedent presentation of neurological phenotypes in the Collaborative Cross reveals four classes with complex sex-dependencies.

# publications[].label
The First Immunocompetent Mouse Model of Strictly Human Pathogen, Borrelia recurrentis.

# publications[].label
EGF receptor is required for KRAS-induced pancreatic tumorigenesis.

# publications[].label
The gastrointestinal microbiome: A malleable, third genome of mammals

# publications[].label
Dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Leveraging a natural murine meiotic drive to suppress invasive populations.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.

# publications[].label
Modeling the cancer patient with genetically engineered mice

# publications[].label
Characterization of EGFR-independent signaling pathways in ApcMin tumors

# publications[].label
Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.

# publications[].label
An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat

# publications[].label
Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras.

# publications[].label
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.

# publications[].label
Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

# publications[].label
Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor inMouse Liver.

# publications[].label
EGFR regulates the expression of keratinocyte-derived granulocyte/macrophage colony-stimulating factor in vitro and in vivo.

# publications[].label
Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

# publications[].label
EGFR regulates the expression of keratinocyte-derived granulocyte/ macrophage colony-stimulating factor in vitro and in vivo

# publications[].label
EGF Receptor Is Required for KRAS-Induced Pancreatic Tumorigenesis

# publications[].label
Mathematical methods for visualization and anomaly detection in telemetry datasets.

# publications[].label
Investigating gene function using mouse models

# publications[].label
Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation.

# publications[].label
Down's syndrome: paradox of a tumour repressor.

# publications[].label
New Zealand White Rabbits Effectively Clear Borrelia burgdorferi B31 despite the Bacterium's Functional vlsE Antigenic Variation System.

# publications[].label
Elucidating Mechanisms of Tolerance to Salmonella Typhimurium across Long-Term Infections Using the Collaborative Cross.

# publications[].label
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
ERBB3 independent activation of the PI3K pathway in EGFR mutant lung adenocarcinomas.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort.

# publications[].label
Proliferation defects in epidermal growth factor receptor null placentae can be rescued in the absence of cyclin-dependent kinase inhibitors.

# publications[].label
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.

# publications[].label
Altered hair follicle morphogenesis in epidermal growth factor receptor deficient mice.

# publications[].label
Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice

# publications[].label
Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor.

# publications[].label
Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence through induction of estrogen metabolizing genes CYP1B1 and COMT

# publications[].label
Hippocampal transcriptome reveals novel targets of FASD pathogenesis.

# publications[].label
Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage

# publications[].label
A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy.

# publications[].label
Quantitative Association Analysis Using Tree Hierarchies

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.

# publications[].label
Comparative transcriptome analysis of Peromyscus leucopus and C3H mice infected with the Lyme disease pathogen.

# publications[].label
Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice.

# publications[].publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)

# publications[].label
Targeted inactivation of EGF receptor inhibits renal collecting duct development and function.

# publications[].label
The Collaborative Cross, a community resource for the genetic analysis of complex traits

# publications[].label
Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men.

# publications[].label
EGFR is required for tumor promotion by dietary fat in a murine model of inflammation-associated colon cancer

# publications[].label
Qualitative trait loci analysis of liver fibrosis using CxB recombinant inbreds

# publications[].label
Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned

# publications[].label
Correction to: Genetic and metabolic links between the murine microbiome and memory.

# publications[].label
Genome-level analysis of genetic regulation of liver gene expression networks

# publications[].label
Epidermal Growth Factor Receptor Deficiency Results in Periimplantation Lethality in Mouse

# publications[].label
Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor.

# publications[].label
Improving Metabolic Health Through Precision Dietetics in Mice.

# publications[].label
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy.

# publications[].label
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

# publications[].label
Using the emerging Collaborative Cross to probe the immune system.

# publications[].label
Using the Collaborative Cross to identify the role of host genetics in defining the murine gut microbiome

# publications[].label
Identifying resistance modifiers of azoxymethane induced colon cancer.

# publications[].label
The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle.

# publications[].label
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

# publications[].label
Quantitative comparison of DNA attachment chemistries as assessed by hybridization to DNA microarrays

# publications[].label
Characterizing Serpinb2 as a Modulator of TCDD-Induced Suppression of the B Cell.

# publications[].label
Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross.

# publications[].label
CHROMOSOMAL ASSIGNMENT OF BOVINE SYNTENIC GROUPS

# publications[].label
Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis.

# publications[].label
Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer

# publications[].label
Chimeric analysis of epidermal growth factor receptor null cells during embryogenesis.

# publications[].label
Serum Cytokines Predict Neurological Damage in Genetically Diverse Mouse Models.

# publications[].label
Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.

# publications[].label
Profiling proteins from azoxymethane-induced colon tumors at the molecular level by matrix-assisted laser desorption/ionization mass spectrometry.

# publications[].label
Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice.

# publications[].label
Identifying modifiers of placental development in EGFR deficient mice.

# publications[].label
Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross.

# publications[].label
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: Effects of dose, route, and diet

# publications[].label
Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus musculus.

# publications[].label
The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice.

# publications[].label
Strain, Sex, and Diet Dependent Responses to American and Ketogenic Diets in Mice

# publications[].label
Locally Fixed Alleles: A method to localize gene drive to island populations.

# publications[].label
Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: roles of transforming growth factor-{alpha} and PTGS2.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Architecture of energy balance traits in emerging lines of the Collaborative Cross

# publications[].label
Physical mapping of the lysozyme gene family in cattle.

# publications[].label
Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation.

# publications[].label
Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.

# publications[].label
Inferring missing genotypes in large SNP panels using fast nearest-neighbor searches over sliding windows.

# publications[].label
Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor

# publications[].label
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains.

# publications[].label
Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.

# publications[].label
Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain.

# publications[].label
Population structure and inbreeding in wild house mice (Mus musculus) at different geographic scales.

# publications[].label
Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo.

# publications[].label
S2051 Stromal Cell EGFR Enhances Colon Cancer Cell Growth in Tumor Xenografts

# publications[].label
Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos.

# publications[].label
Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler's Murine Encephalomyelitis Virus (TMEV) infection.

# researcherOn[].awardedBy.label
Environmental Protection Agency - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Tolerance Mechanisms Through Innovative Population Analysis

# researcherOn[].awardedBy.label
United States Department of Defense - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Epigenetic Signatures of Developmental Reprogramming in Target and Surrogate Tissues

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Chromatin regions, genes and pathways that confer susceptibility to chemical-induced DNA damage

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
Modeling Heterogeneity for Safe Cancer Prevention and Detection

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Targeting Insulin Resistance by Estrogen Receptor in Control of Type 2 Diabetes Mellitus

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Diabetes and Digestive and Kidney Disorders

# researcherOn[].label
IMSD at Texas A&M University:  Initiative for Maximizing Student Diversity in Biomedical Sciences

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of General Medical Science

# researcherOn[].label
Texas A&M Center for Environmental Health Research

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
Host Genetic Determinants of Diversity in Viral-Induced Neuropathology

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Neurological Disorders and Stroke

# researcherOn[].label
Center for Translational Environmental Health Research

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
A New Paradigm for Ovarian Sex Cord-Stromal Tumor Development

# researcherOn[].awardedBy.label
United States Army - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
DOD-Army-Medical Research and Materiel Command

# researcherOn[].label
Diverse Predoctoral Training in Genetics

# researcherOn[].awardedBy.label
National Institute of General Medical Sciences - (Bethesda, Maryland, United States)

# researcherOn[].label
Development of murine model of neuroborreliosis

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Allergy and Infectious Diseases

# researcherOn[].label
Comprehensive Tools and Models for Addressing Exposure to Mixtures During Environmental Emergency-Related Contamination Events

# researcherOn[].awardedBy.label
National Institute of Environmental Health Sciences - (Durham, North Carolina, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Environmental Health Sciences

# researcherOn[].label
Veterinary Pest Genome and Transcriptome Bioinformatic Analysis

# researcherOn[].awardedBy.label
Agricultural Research Service - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Cardiotoxicity Adverse Outcome Pathway Center: Organotypic Culture Model and In Vitro-to-In Vivo Extrapolation for High-Throughput Hazard, Dose-Response and Variability Assessments

# researcherOn[].awardedBy.label
Environmental Protection Agency - (Washington D.C., District of Columbia, United States)

# streetAddress
Texas A&M University; Vet Med Pathobiology; 4467 TAMU

# organizations[]
Institute of Genome Sciences and Society

# schools[]
College of Agriculture and Life Sciences

# inTheNews[].label
Texas A&M AgriLife's newest Regents Professors, Fellows

# inTheNews[].label
Texas A&M System Regents Approve 14 Texas A&M University Regents Professors And Regents Fellows

# etdChairOf[].label
Warren, Melanie Renai (2019-04). Population Variability and the Teratogenic Effects of Dioxin During Pregnancy. Doctoral Dissertation.

# etdChairOf[].label
Howe, Selene Yelaine Fernandez (2018-12). Chemopreventative and Cardiotoxic Effects from Long-Term EGFR Pharmaceutical Inhibition. Doctoral Dissertation.

# etdChairOf[].label
Perry, Amie Lynn (2019-02). Renal Health Effects in Trichloroethylene and Arsenic Co-Exposed Mice. Doctoral Dissertation.

# etdChairOf[].label
Mantilla Rojas, Carolina (2019-11). Implications of ERBB Receptor Tyrosine Kinase Signaling in Resistance to EGRF-Targeted Therapies in Colorectal Cancer. Doctoral Dissertation.