# positions[].organizations[].parent[].label
College of Veterinary Medicine and Biomedical Sciences

# positions[].organizations[].parent[].label
School of Veterinary Medicine and Biomedical Sciences

# overview
My lab is focused on understanding epimorphic and tissue regeneration in mammals.

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
Receptor, Transforming Growth Factor-beta Type I

# keywords[]
Platelet Endothelial Cell Adhesion Molecule-1

# keywords[]
1.1 Normal Biological Development And Functioning

# educationAndTraining[].organization.label
Humboldt State University - (Arcata, California, United States)

# educationAndTraining[].organization.label
University of California, Irvine - (Irvine, California, United States)

# educationAndTraining[].organization.label
University of California, Irvine - (Irvine, California, United States)

# publications[].label
Limb Regrowth and Tissue Engineering Alternatives

# publications[].label
Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton.

# publications[].label
Cellular contribution from dermis and cartilage to the regenerating limb blastema in axolotls.

# publications[].label
Macrophages are required to coordinate mouse digit tip regeneration.

# publications[].label
BMP signaling induces digit regeneration in neonatal mice.

# publications[].label
Angiogenesis is inhibitory for mammalian digit regeneration.

# publications[].label
3T3 cell integration and differentiative potential during limb development in the mouse.

# publications[].label
Improved techniques for use of the triploid cell marker in the axolotl, Ambystoma mexicanum.

# publications[].label
Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine.

# publications[].label
A quantitative analysis of regeneration from chimaeric limb stumps in the axolotl.

# publications[].label
A new method for mechanical dechorionation of ascidian eggs.

# publications[].label
Analogous cellular contribution and healing mechanisms following digit amputation and phalangeal fracture in mice.

# publications[].label
Digit regeneration is regulated by Msx1 and BMP4 in fetal mice.

# publications[].label
Cell migration and chick limb development: chemotactic action of FGF-4 and the AER.

# publications[].label
FGF-2 induces regeneration of the chick limb bud.

# publications[].label
Position specific growth regulation of 3T3 cells in vivo.

# publications[].label
Mouse embryonic diastema region is an ideal site for the development of ectopically transplanted tooth germ.

# publications[].label
Novel explant culture model for evaluation of oxygen signaling during mammalian digit regeneration

# publications[].label
Positional information in axolotl and mouse limb extracellular matrix is mediated via heparan sulfate and fibroblast growth factor during limb regeneration in the axolotl (Ambystoma mexicanum).

# publications[].label
Intrinsic control of regenerative loss in Xenopus laevis limbs.

# publications[].label
Regeneration from discontinuous circumferences in axolotl limbs.

# publications[].label
Conversion by retinoic acid of anterior cells into ZPA cells in the chick wing bud.

# publications[].label
Limb regeneration in higher vertebrates: developing a roadmap.

# publications[].label
Embryonic chicken model of joint regeneration recapitulates joint development

# publications[].label
In utero and exo utero surgery on rodent embryos.

# publications[].label
FGF-2 influences cell movements and gene expression during limb development.

# publications[].label
Maintenance of ZPA signaling in cultured mouse limb bud cells.

# publications[].label
Cellular contribution to supernumerary limbs resulting from the interaction between developing and regenerating tissues in the axolotl.

# publications[].label
Endogenous Bone Regeneration Is Dependent Upon a Dynamic Oxygen Event

# publications[].label
MPLB-2: a posterior signaling cell line derived from the mouse limb bud.

# publications[].label
Epidermal closure regulates histolysis during mammalian (Mus) digit regeneration.

# publications[].label
BMP2 induces segment-specific skeletal regeneration from digit and limb amputations by establishing a new endochondral ossification center.

# publications[].label
Influence of FGF4 on digit morphogenesis during limb development in the mouse.

# publications[].label
Differential cell affinity and sorting of anterior and posterior cells during outgrowth of recombinant avian limb buds.

# publications[].label
Dlx5 and Msx2 regulate mouse anterior neural tube closure through ephrinA5-EphA7.

# publications[].label
Appositional bone growth and digit regeneration in mice and humans.

# publications[].label
Pattern discontinuity, polarity and directional intercalation in axolotl limbs.

# publications[].label
The migration of dermal cells during blastema formation in axolotls.

# publications[].label
BMP9 stimulates joint regeneration at digit amputation wounds in mice.

# publications[].label
Sirtuin 3 deficiency does not impede digit regeneration in mice.

# publications[].label
Evidence for regulation following amputation and tissue grafting in the developing mouse limb.

# publications[].label
SDF-1/CXCR4 signaling mediates digit tip regeneration promoted by BMP-2.

# publications[].label
Regenerative phenotype in mice with a point mutation in transforming growth factor beta type I receptor (TGFBR1).

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
The periosteal requirement and temporal dynamics of BMP2-induced middle phalanx regeneration in the adult mouse.

# publications[].label
Induced regeneration of articular cartilage - identification of a dormant regeneration program for a non-regenerative tissue.

# publications[].label
The blastema and epimorphic regeneration in mammals.

# publications[].label
In vitro maintenance of posterior (ZPA) signaling in mouse limb bud cells.

# publications[].label
Blastema formation and periosteal ossification in the regenerating adult mouse digit.

# publications[].label
Mouse digit regeneration: a new model to study age-related regenerative decline.

# publications[].label
Molecular aspects of regeneration in developing vertebrate limbs.

# publications[].label
Do chick limb bud cells have positional information?

# publications[].label
Gene expression during the first 28 days of axolotl limb regeneration I: Experimental design and global analysis of gene expression.

# publications[].label
The mammalian blastema: regeneration at our fingertips.

# publications[].label
Digit Tip Regeneration: Merging Regeneration Biology with Regenerative Medicine.

# publications[].label
The mouse digit tip: from wound healing to regeneration.

# publications[].label
Wound healing and blastema formation in regenerating digit tips of adult mice.

# publications[].label
Male Down syndrome Ts65Dn mice have impaired bone regeneration.

# publications[].label
Regeneration in higher vertebrates: limb buds and digit tips.

# publications[].label
Connective tissue fibroblast properties are position-dependent during mouse digit tip regeneration.

# publications[].label
Axonal regrowth is impaired during digit tip regeneration in mice.

# publications[].label
Increased oxygen enhances bone degradation and promotes bone regeneration after digit amputation in mice

# publications[].label
Mouse embryos develop normally exo utero.

# publications[].label
Development and regeneration of the neonatal digit tip in mice.

# publications[].label
Position-specific growth of mouse limb bud cells in vitro.

# publications[].label
Inhibition of polarizing activity in the anterior limb bud is regulated by extracellular factors.

# publications[].label
Mapping the early development of projections from the entorhinal cortex in the embryonic mouse using prenatal surgery techniques.

# publications[].label
Intercalation and the cellular origin of supernumerary limbs in Xenopus.

# publications[].label
The role of Msx1 and Bmp4 in digit tip regeneration of mice.

# publications[].label
Conversion of anterior limb bud cells to ZPA signaling cells in vitro and in vivo.

# publications[].label
Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice.

# publications[].label
Fibroblast reticular cells engineer a blastema extracellular network during digit tip regeneration in mice.

# publications[].label
Adult Mouse Digit Amputation and Regeneration: A Simple Model to Investigate Mammalian Blastema Formation and Intramembranous Ossification.

# publications[].label
Hindlimb Unloading (HU) Inhibits Regeneration of the Mouse Digit Tip.

# publications[].label
VIEWS OF LIMB DEVELOPMENT AND REGENERATION

# publications[].label
Mammalian limb bud development: in situ fate maps of early hindlimb buds.

# publications[].label
A staging system for mouse limb development.

# publications[].label
Cellular contribution to supernumerary limbs in the axolotl, Ambystoma mexicanum.

# publications[].label
Evidence that patterning mechanisms in developing and regenerating limbs are the same.

# publications[].label
Physiological aspects of blastema formation in mice

# publications[].label
Regeneration of the elbow joint in the developing chick embryo recapitulates development.

# publications[].label
Periosteal chondrogenesis and temporal dynamics of BMP2-induced middle phalanx regeneration in the adult mouse.

# publications[].label
The Impact of Aging on Mechanisms of Mammalian Epimorphic Regeneration.

# publications[].label
The mouse digit tip: From wound healing to regeneration

# publications[].label
Endogenous bone regeneration is dependent upon a dynamic oxygen event.

# publications[].label
Regeneration of HoxD expression domains during pattern regulation in chick wing buds.

# streetAddress
Texas A&M University; Vet Med - Physiology & Pharmacology; 4466 TAMU

# organizations[]
College of Veterinary Medicine and Biomedical Sciences

# organizations[]
School of Veterinary Medicine and Biomedical Sciences

# schools[]
College of Veterinary Medicine and Biomedical Sciences

# schools[]
School of Veterinary Medicine and Biomedical Sciences