# positions[].organizations[].parent[].label
College of Veterinary Medicine and Biomedical Sciences

# positions[].organizations[].parent[].label
School of Veterinary Medicine and Biomedical Sciences

# overview
Comparative genomics and molecular cytogenetics of animals, birds and other vertebrates organization, function and evolution of sex chromosomes; equine genomics - genomics of genetic diseases and disorders of sexual development and reproduction; alpaca and camelid genomics.

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Sex Chromosome Disorders Of Sex Development

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Serotonin Plasma Membrane Transport Proteins

# keywords[]
Human Epidermal Growth Factor Receptor 2

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Nk Cell Lectin-like Receptor Subfamily C

# keywords[]
Nk Cell Lectin-like Receptor Subfamily D

# educationAndTraining[].organization.label
Swedish University of Agricultural Sciences - (Uppsala, Sweden)

# awardsAndHonors[].label
Montague Center for Teaching Excellence (CTE) Scholar

# publications[].label
Novel gene acquisition on carnivore Y chromosomes.

# publications[].label
Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era.

# publications[].label
Clinical and Histological Features of Ovarian Hypoplasia/Dysgenesis in Alpacas.

# publications[].label
Total RNA isolation from stallion sperm and testis biopsies.

# publications[].label
Ambiguous external genitalia in a 5-year-old intact miniature equid.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Identification of candidate proteins associated with impaired acrosomal exocytosis in Thoroughbred stallions using Data-Independent Acquisition mass spectrometry (DIA-MS)

# publications[].label
Comparison of horse chromosome 3 with donkey and human chromosomes by cross-species painting and heterologous FISH mapping.

# publications[].label
Comparative mapping in the pig: localization of 214 expressed sequence tags.

# publications[].label
Gene discovery and comparative analysis of X-degenerate genes from the domestic cat Y chromosome.

# publications[].label
Thirty-five new equine microsatellite loci assigned to genetic linkage and radiation hybrid maps.

# publications[].label
Chromosome-Level Alpaca Reference Genome VicPac3.1 Improves Genomic Insight Into the Biology of New World Camelids.

# publications[].label
Trio-binning of a hinny refines the comparative organization of the horse and donkey X chromosomes and reveals novel species-specific features.

# publications[].label
Potential applications of equine genomics in dissecting diseases and fertility.

# publications[].label
A high-resolution radiation hybrid map of the river buffalo major histocompatibility complex and comparison with BoLA.

# publications[].label
Sequence analysis in Bos taurus reveals pervasiveness of X-Y arms races in mammalian lineages.

# publications[].label
FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
XX/XY Blood Lymphocyte Chimerism in Heterosexual Dizygotic Twins from an American Bashkir Curly Horse. Case Report

# publications[].label
Towards generating a 1-Mb resolution map of the horse X chromosome

# publications[].label
Evolutionary conservation of Y Chromosome ampliconic gene families despite extensive structural variation.

# publications[].label
Analysis of genomic copy number variation in equine recurrent airway obstruction (heaves).

# publications[].label
A multi-platform draft de novo genome assembly and comparative analysis for the Scarlet Macaw (Ara macao).

# publications[].label
Theriogenology question of the month. Segmental aplasia of the uterine horn with mucometra.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Isolation, characterization and FISH assignments of horse BAC clones containing type I and II markers.

# publications[].label
The Second Case of Non-Mosaic Trisomy of Chromosome 26 with Homologous Fusion 26q;26q in the Horse.

# publications[].label
Low frequency of microsatellites in the avian genome.

# publications[].label
Cytogenetic and molecular characterization of Y isochromosome in a 63XO/64Xi(Yq) mosaic karyotype of an intersex horse.

# publications[].label
An 8.22 Mb Assembly and Annotation of the Alpaca (Vicugna pacos) Y Chromosome.

# publications[].label
The first physical map - RH and FISH - of the equine Y chromosome

# publications[].label
Horse Y chromosome assembly displays unique evolutionary features and putative stallion fertility genes.

# publications[].label
A detailed physical map of the horse Y chromosome.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Skeletal variation in Tennessee Walking Horses maps to the LCORL/NCAPG gene region.

# publications[].label
Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution.

# publications[].label
Long-term expansion of primary equine keratinocytes that maintain the ability to differentiate into stratified epidermis.

# publications[].label
A gene catalogue of the euchromatic male-specific region of the horse Y chromosome: comparison with human and other mammals.

# publications[].label
Molecular characterization of the equine testis-specific protein 1 (TPX1) and acidic epididymal glycoprotein 2 (AEG2) genes encoding members of the cysteine-rich secretory protein (CRISP) family.

# publications[].label
Genetics of Sex-linked yellow in the Syrian hamster.

# publications[].label
The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins.

# publications[].label
Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions.

# publications[].label
Refining the evolutionary tree of the horse Y chromosome.

# publications[].label
A 4,103 marker integrated physical and comparative map of the horse genome.

# publications[].label
A Non-Reciprocal Autosomal Translocation 64,XX, t(4;10)(q21;p15) in an Arabian Mare with Repeated Early Embryonic Loss.

# publications[].label
Correspondence of human chromosomes 9, 12, 15, 16, 19 and 20 with donkey chromosomes refines homology between horse and donkey karyotypes.

# publications[].label
Clusters of overlapping BACs on the euchromatic region of the equine Y

# publications[].label
Conservation of gene order between horse and human X chromosomes as evidenced through radiation hybrid mapping (vol 79, pg 451, 2002)

# publications[].label
SNP detection and radiation hybrid mapping in horses of nine candidate genes for temperament.

# publications[].label
Cytogenetic Mapping of 35 New Markers in the Alpaca (Vicugna pacos).

# publications[].label
Zoo-FISH delineates conserved chromosomal segments in horse and man.

# publications[].label
Erratum: The first-generation whole-genome radiation hybrid map in the horse identifies conserved segments in human and mouse genomes (Genome Research (2003) vol. 13 (742-751))

# publications[].label
The pseudoautosomal region and sex chromosome aneuploidies in domestic species.

# publications[].label
Genetic mapping of GBE1 and its association with glycogen storage disease IV in American Quarter horses.

# publications[].label
A rare finding of double Barr bodies and X-monosomy/X-trisomy mosaicism in a dog with presumed idiopathic epilepsy.

# publications[].label
A 1.3-Mb interval map of equine homologs of HSA2.

# publications[].label
High-resolution RH map of horse chromosome 22 reveals a putative ancestral vertebrate chromosome.

# publications[].label
Development and Application of Molecular Tools for Camelid Cytogenetics

# publications[].label
Male horse meiosis: metaphase I chromosome configuration and chiasmata distribution.

# publications[].label
Novel Complex Unbalanced Dicentric X-Autosome Rearrangement in a Thoroughbred Mare with a Mild Effect on the Phenotype.

# publications[].label
Zoo-FISH with microdissected arm specific paints for HSA2, 5, 6, 16, and 19 refines known homology with pig and horse chromosomes.

# publications[].label
Blood chimerism confounds genetic relative susceptibility testing for classical scrapie in sheep.

# publications[].label
Repeated Early Embryonic Loss in a Thoroughbred Mare with a Chromosomal Translocation [64,XX,t(2;13)]

# publications[].label
Does inbreeding contribute to pregnancy loss in Thoroughbred horses?

# publications[].label
Molecular Cytogenetic and Y Copy Number Analysis of a Reciprocal ECAY-ECA13 Translocation in a Stallion with Complete Meiotic Arrest.

# publications[].label
Genetics of Equine Reproductive Diseases.

# publications[].label
The horse pseudoautosomal region (PAR): characterization and comparison with the human, chimp and mouse PARs.

# publications[].label
Copy number variation of horse Y chromosome genes in normal equine populations and in horses with abnormal sex development and subfertility: relationship of copy number variations with Y haplogroups.

# publications[].label
Thoroughbred stallion fertility is significantly associated with FKBP6 genotype but not with inbreeding or the contribution of a leading sire.

# publications[].label
Report of the Third International Committee for the standardization of the domestic horse Karyotype, Davis, CA, USA, 1996. International system for cytogenetic nomenclature of the domestic horse

# publications[].label
Comparative FISH mapping of 32 loci reveals new homologous regions between donkey and horse karyotypes.

# publications[].label
Construction of a medium-density horse gene map.

# publications[].label
Molecular Genetic Testing and Karyotyping in the Horse

# publications[].label
Characterization of the bovine pseudoautosomal region and comparison with sheep, goat, and other mammalian pseudoautosomal regions.

# publications[].label
Stallion sperm transcriptome comprises functionally coherent coding and regulatory RNAs as revealed by microarray analysis and RNA-seq.

# publications[].label
Exceptional conservation of horse-human gene order on X chromosome revealed by high-resolution radiation hybrid mapping.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
FISH mapping of the IGF2 gene in horse and donkey-detection of homoeology with HSA11.

# publications[].label
Efficient correction of a deleterious point mutation in primary horse fibroblasts with CRISPR-Cas9.

# publications[].label
Sixty-seven new equine microsatellite loci assigned to the equine radiation hybrid map.

# publications[].label
Remarkable synteny conservation of melanocortin receptors in chicken, human, and other vertebrates.

# publications[].label
The horse genome derby: racing from map to whole genome sequence.

# publications[].label
Conservation genetic analysis of the Texas State Bison Herd

# publications[].label
Azoospermia and Y Chromosome-Autosome Translocation in aFriesian Stallion.

# publications[].label
A comprehensive whole-genome integrated cytogenetic map for the alpaca (Lama pacos).

# publications[].label
Development and application of camelid molecular cytogenetic tools.

# publications[].label
Interstitial telomeric sites and NORs in Hartmann's zebra (Equus zebra hartmannae) chromosomes.

# publications[].label
Mapping genomes at the chromosome level.

# publications[].label
Construction of chromosome-specific paints for meta- and submetacentric autosomes and the sex chromosomes in the horse and their use to detect homologous chromosomal segments in the donkey.

# publications[].label
Comparative analysis of mammalian Y chromosomes illuminates ancestral structure and lineage-specific evolution.

# publications[].label
An ordered BAC contig map of the equine major histocompatibility complex.

# publications[].label
Generation of a Biobank From Two Adult Thoroughbred Stallions for the Functional Annotation of Animal Genomes Initiative.

# publications[].label
A comprehensive gene catalog of the horse Y chromosome.

# publications[].label
Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD.

# publications[].label
Evaluation of culture systems for attachment and proliferation of epithelial cells cultured from ovine semen.

# publications[].label
Fertility Assessment in Sorraia Stallions by Sperm-Fish and Fkbp6 Genotyping.

# publications[].label
A high-resolution physical map of equine homologs of HSA19 shows divergent evolution compared with other mammals.

# publications[].label
Sequence, detection of polymorphisms and radiation hybrid mapping of the equine catechol-o-methyltransferase gene.

# publications[].label
A 1.4-Mb interval RH map of horse chromosome 17 provides detailed comparison with human and mouse homologues.

# publications[].label
The role of impaired acrosomal exocytosis (IAE) in stallion subfertility: A retrospective analysis of the clinical condition, and an update on its diagnosis by high throughput technologies.

# publications[].label
Array CGH Studies in Equine Disorders of Sexual Development - SRY-Positive Sex Reversal and Cryptorchidism

# publications[].label
Chromosome Aberrations and Fertility Disorders in Domestic Animals.

# publications[].label
Lethal variants of equine pregnancy: is it the placenta or foetus leading the conceptus in the wrong direction?

# publications[].label
Comparative mapping in equids: the asine X chromosome is rearranged compared to horse and Hartmann's mountain zebra.

# publications[].label
Validation of a candidate causative mutation for white spotting in donkeys.

# publications[].label
Polymorphism identification, RH mapping, and association analysis with the anxiety trait of the equine serotonin transporter (SLC6A4) gene.

# publications[].label
HSA4 and GGA4: remarkable conservation despite 300-Myr divergence.

# publications[].label
Emerging patterns of comparative genome organization in some mammalian species as revealed by Zoo-FISH.

# publications[].label
Linkage and comparative mapping of the locus controlling susceptibility towards E. COLI F4ab/ac diarrhoea in pigs.

# publications[].label
Ancient segmentally duplicated LCORL retrocopies in equids.

# publications[].label
PROFILING OF STRUCTURAL GENOMIC VARIANTS IN PLACENTAE FROM MARES THAT SUFFER EARLY PREGNANCY LOSS

# publications[].label
Whole genome analysis reveals aneuploidies in early pregnancy loss in the horse.

# publications[].label
Comparative FISH-Mapping of MC1R, ASIP, and TYRP1 in New and Old World Camelids and Association Analysis With Coat Color Phenotypes in the Dromedary (Camelus dromedarius).

# publications[].label
Assignment of six genes to bovine chromosomes 5 and 16 by fluorescence in situ hybridization, radiation hybrid mapping and genetic linkage analysis.

# publications[].label
Genome sequence, comparative analysis, and population genetics of the domestic horse.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Microdissection of pig chromosomes: dissection of whole chromosomes, arms and bands for construction of paints and libraries.

# publications[].label
Comparative Chromosome Painting in Genets (Carnivora, Viverridae, Genetta), the Only Known Feliforms with a Highly Rearranged Karyotype.

# publications[].label
Construction of a 5000(rad) whole-genome radiation hybrid panel in the horse and generation of a comprehensive and comparative map for ECA11.

# publications[].label
The horse Y chromosome as an informative marker for tracing sire lines.

# publications[].label
A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae.

# publications[].label
Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Population Genetic Analysis of the Estonian Native Horse Suggests Diverse and Distinct Genetics, Ancient Origin and Contribution from Unique Patrilines.

# publications[].label
Comparative organization and gene expression profiles of the porcine pseudoautosomal region.

# publications[].label
Identification and Expression Analysis of the Pig Pseudoautosomal Region Using Molecular Cytogenetics Approach

# publications[].label
Ovarian dysgenesis in an alpaca with a minute chromosome 36.

# publications[].label
HER2 Overexpression and Amplification in Feline Pulmonary Carcinoma.

# publications[].label
Cytogenetics of donkey chromosomes: nomenclature proposal based on GTG-banded chromosomes and depiction of NORs and telomeric sites.

# publications[].label
Two Novel Cases of Autosomal Translocations in the Horse: Warmblood Family Segregating t(4;30) and a Cloned Arabian with a de novo t(12;25).

# publications[].label
Evolutionary movement of centromeres in horse, donkey, and zebra.

# publications[].label
Molecular heterogeneity of XY sex reversal in horses.

# publications[].label
Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution.

# publications[].label
An Autosomal Translocation 73,XY,t(12;20)(q11;q11) in an Infertile Male Llama (Lama glama) With Teratozoospermia.

# publications[].label
High-resolution gene maps of horse chromosomes 14 and 21: additional insights into evolution and rearrangements of HSA5 homologs in mammals.

# publications[].label
Comparative Cytogenetics of the Congo African Grey Parrot (Psittacus erithacus).

# publications[].label
Single linkage group per chromosome genetic linkage map for the horse, based on two three-generation, full-sibling, crossbred horse reference families.

# publications[].label
Cytogenetic analysis of California condor (Gymnogyps californianus) chromosomes: comparison with chicken (Gallus gallus) macrochromosomes.

# publications[].label
Chicken CD69 and CD94/NKG2-like genes in a chromosomal region syntenic to mammalian natural killer gene complex.

# publications[].label
Establishment, characterization, and toxicological application of loggerhead sea turtle (Caretta caretta) primary skin fibroblast cell cultures.

# publications[].label
Chromosomal distribution, localization and expression of the human endogenous retrovirus ERV9.

# publications[].label
A BAC contig map over the proximal approximately 3.3 Mb region of horse chromosome 21.

# publications[].label
The first-generation whole-genome radiation hybrid map in the horse identifies conserved segments in human and mouse genomes.

# publications[].label
Chromosomal Localization of Candidate Genes for Fiber Growth and Color in Alpaca (Vicugna pacos).

# publications[].label
A cytogenetic and comparative map of camelid chromosome 36 and the minute in alpacas.

# publications[].publisher
American Veterinary Medical Association (AVMA)

# publications[].label
Copy number variation in the horse genome.

# publications[].label
Evolution of the avian sex chromosomes from an ancestral pair of autosomes.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Radiation hybrid mapping of 75 previously unreported equine microsatellite loci.

# publications[].label
Horse Clinical Cytogenetics: Recurrent Themes and Novel Findings.

# publications[].label
A high resolution RH map of the bovine major histocompatibility complex.

# publications[].label
Case Report: Disorder of Sexual Development in a Chinese Crested Dog With XX/XY Leukocyte Chimerism and Mixed Cell Testicular Tumors.

# publications[].label
Large Deletions at the SHOX Locus in the Pseudoautosomal Region Are Associated with Skeletal Atavism in Shetland Ponies.

# publications[].label
Characterization of A Homozygous Deletion of Steroid Hormone Biosynthesis Genes in Horse Chromosome 29 as A Risk Factor for Disorders of Sex Development and Reproduction.

# publications[].label
The 450-band resolution G- and R-banded standard karyotype of the donkey (Equus asinus, 2n = 62).

# publications[].label
International system for cytogenetic nomenclature of the domestic horse. Report of the Third International Committee for the Standardization of the domestic horse karyotype, Davis, CA, USA, 1996.

# publications[].label
Radiation hybrid mapping of 63 previously unreported equine microsatellite loci.

# publications[].label
Diagnosis of XX/XY Blood Cell Chimerism at a Low Percentage in Horses

# publications[].label
Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns.

# publications[].label
Natural killer cell receptors in the horse: evidence for the existence of multiple transcribed LY49 genes.

# publications[].label
Chromosome-level reference genome for North American bison (Bison bison) and variant database aids in identifying albino mutation.

# publications[].label
Case Study: Polymelia in a Holstein calf

# publications[].publisher
American Registry of Professional Animal Scientists

# publications[].label
Conservation of gene order between horse and human X chromosomes as evidenced through radiation hybrid mapping.

# publications[].label
Generation of an equine biobank to be used for Functional Annotation of Animal Genomes project.

# publications[].label
Chromosome painting in farm, pet and wild animal species.

# publications[].label
Chromosomal assignments for the equine AMPK family genes.

# publications[].label
Repetitive exon 45/46-related sequences of human Ca2+ channel alpha1C subunit gene.

# researcherOn[].label
Sequencing and Functional Analysis of the Horse Y Chromosome

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# researcherOn[].label
Refining the sequence and annotation of complex regions in the horse sex chromosomes to enhance knowledge of functionally important genes

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# streetAddress
Texas A&M University; Veterinary Integrative Biosciences; 4458 TAMU

# organizations[]
College of Veterinary Medicine and Biomedical Sciences

# organizations[]
School of Veterinary Medicine and Biomedical Sciences

# schools[]
College of Veterinary Medicine and Biomedical Sciences

# schools[]
School of Veterinary Medicine and Biomedical Sciences

# inTheNews[].label
Important cause of early pregnancy losses in mares pinpointed

# inTheNews[].label
The bull Y chromosome has evolved to bully its way into gametes

# etdChairOf[].label
Jevit, Matthew John (2022-12). Dissecting the Most Complex Regions of the Mammalian Genome; the Sex Chromosomes. Doctoral Dissertation.

# etdChairOf[].label
Hernandez Aviles, Juan Camilo (2022-08). Studies on the Acrosomal Function of Sperm from Fertile and Subfertile Stallions. Doctoral Dissertation.

# etdChairOf[].label
Alshanbari, Fahad (2019-12). Genomic Studies in the Dromedary (Camelus dromedarius). Doctoral Dissertation.

# etdChairOf[].label
Castaneda, Caitlin Patricia (2022-08). Dissecting Genomic Factors of Stallion Fertility. Doctoral Dissertation.

# etdChairOf[].label
Fagundes De Avila, Felipe (2014-08). Comparative Mapping of the Alpaca Genome. Doctoral Dissertation.