# overview
My research focuses on identifying novel cellular and molecular approaches to reconstruct spinal cord neural circuits and restore neurological function after spinal cord injury. We seek to answer fundamental biological questions about how transplanted neural progenitor cells interact with, and integrate into, the injured host nervous system. Our long-term goal is to generate knowledge that will be applied toward the engineering of therapeutically effective human cell therapies.

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Stem Cell Research - Nonembryonic - Non-human

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Stem Cell Research - Nonembryonic - Human

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5 Development Of Treatments And Therapeutic Interventions

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Machine Learning And Artificial Intelligence

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Physical Injury - Accidents And Adverse Effects

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4201 Allied Health And Rehabilitation Science

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Physical Injury - Accidents And Adverse Effects

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Reverse Transcriptase Polymerase Chain Reaction

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Atp Binding Cassette Transporter, Subfamily B

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Atp Binding Cassette Transporter, Subfamily B, Member 1

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Reverse Transcriptase Polymerase Chain Reaction

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Physical Injury - Accidents And Adverse Effects

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Stem Cell Research - Nonembryonic - Non-human

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1.1 Normal Biological Development And Functioning

# educationAndTraining[].organization.label
The University of Texas Health Science Center at Houston - (Houston, Texas, United States)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# publications[].label
Effects of biological sex mismatch on neural progenitor cell transplantation for spinal cord injury in mice.

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Bridging the injured spinal cord with neural stem cells.

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Developmental stage of transplanted neural progenitor cells influences anatomical and functional outcomes after spinal cord injury in mice.

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Tempo and Mode of Genome Structure Evolution in Insects.

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Chapter 15 Spinal interneurons and cell transplantation

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Transplanting neural progenitor cells to restore connectivity after spinal cord injury.

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The Importance of Undergraduate Research Experiences.

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Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.

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Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury.

# publications[].label
Transcription Factor Hb9 Is Expressed in Glial Cell Lineages in the Developing Mouse Spinal Cord.

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Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

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Biomimetic 3D-printed scaffolds for spinal cord injury repair.

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Intraspinal and Intracortical Delivery of AAV Vectors for Intersectional Circuit Tracing in Non-transgenic Species.

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The Emerging Role of Biological Sex in Cell Therapy for Spinal Cord Injury.

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Dorsal horn neuronal sparing predicts the development of at-level mechanical allodynia following cervical spinal cord injury in mice.

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Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury

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Systematic analysis of federal funding for spinal cord injury research.

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Fighting for recovery on multiple fronts: The past, present, and future of clinical trials for spinal cord injury.

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An Analysis of Variability in "CatWalk" Locomotor Measurements to Aid Experimental Design and Interpretation.

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In Memoriam: Ray Grill (1966-2018) OBITUARY

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An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation.

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Transcriptomic Approaches to Neural Repair.

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The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord.

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Editorial: Fighting for recovery on multiple fronts in spinal cord injury.

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Implications of regional identity for neural stem and progenitor cell transplantation in the injured or diseased nervous system

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Publisher Correction: Developmental stage of transplanted neural progenitor cells influences anatomical and functional outcomes after spinal cord injury in mice.

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Spinal cord injury causes sustained disruption of the blood-testis barrier in the rat.

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AxonTracer: a novel ImageJ plugin for automated quantification of axon regeneration in spinal cord tissue.

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Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts.

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Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration.

# publications[].label
Disruption of G3BP1 granules promotes mammalian CNS and PNS axon regeneration.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
Adult rat myelin enhances axonal outgrowth from neural stem cells.

# publications[].publisher
American Association for the Advancement of Science (AAAS)

# publications[].label
Functional synaptic connectivity of engrafted spinal cord neurons with locomotor circuitry in the injured spinal cord.

# publications[].label
Normobaric hyperoximia increases hypoxia-induced cerebral injury: DTI study in rats.

# publications[].label
EFFECTS OF DEVELOPMENTAL RESTRICTION ON NEURAL PROGENITOR GRAFT COMPOSITION AND RECOVERY OF FUNCTION FOLLOWING SPINAL CORD INJURY

# researcherOn[].label
Dissecting Connectivity and Function of Transplanted Interneurons in the Injured Spinal Cord

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

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Determination of Optimal Neural Progenitor Cell Sources for SCI Studies

# researcherOn[].awardedBy.label
Craig H Neilsen Foundation - (Los Angeles, California, United States)

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Neural Progenitor Cells for Mitigating Pain after Spinal Cord Injury

# researcherOn[].awardedBy.label
Craig H Neilsen Foundation - (Los Angeles, California, United States)

# researcherOn[].label
Corticospinal tract regeneration via NF-kB inhibition

# researcherOn[].awardedBy.label
Craig H Neilsen Foundation - (Los Angeles, California, United States)

# streetAddress
Texas A&M University; Biology; 3474 TAMU