# overview
We have yet to understand how embryonic brain development gives rise to brain function and how deficits in this process lead to brain disorders. To help improve this understanding, I'm interested in developing accessible microscopy, labeling, visualization, and bioimage informatics tools for creating multi-scale models of the emergence of brain structure and function.

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Stem Cell Research - Nonembryonic - Human

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
Cell Culture Techniques, Three Dimensional

# educationAndTraining[].organization.label
University of Edinburgh - (Edinburgh, United Kingdom)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# publications[].label
Image-Based Structural Modeling of the Early-Stage Zebrafish Embryo Brain

# publications[].label
Digitizing Vertebrate Brain Development with Ultrashort Pulse Microscopy

# publications[].label
Implementation of Bessel-like LP02 Mode from Higher Order Mode (HOM) Fiber to extend the Depth of Focus in Fourier Domain Optical Coherence Microscopy (FD-OCM)

# publications[].label
Modeling the Image Formation Process in Fourier Domain Optical Coherence Microscopy for a Bessel-like LP02 Mode from a Higher Order Mode Fiber

# publications[].label
Advances in nonlinear optical microscopy for visualizing dynamic tissue properties in culture.

# publications[].label
Combined lineage mapping and gene expression profiling of embryonic brain patterning using ultrashort pulse microscopy and image registration.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Compact spectrograph for hyperspectral imaging with overlapping fluorescent reporters

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Building a three-dimensional model of early-stage zebrafish embryo brain.

# publications[].label
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction

# publications[].label
Aberration correction of sub-10-fs pulse focusing with high-numerical-aperture microscope objective

# publications[].label
Imaging embryonic development with ultrashort pulse microscopy

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Loss of smooth muscle -actin effects on mechanosensing and cell-matrix adhesions.

# publications[].label
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction.

# publications[].label
Navigating the Light-Sheet Image Analysis Software Landscape: Concepts for Driving Cohesion From Data Acquisition to Analysis.

# publications[].label
Volumetric Imaging of Human Mesenchymal Stem Cells (hMSCs) for Non-Destructive Quantification of 3D Cell Culture Growth

# publications[].label
Passive pressure-diameter relationship and structural composition of rat mesenteric lymphangions.

# publications[].label
Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth.

# publications[].label
Nck deficiency is associated with delayed breast carcinoma progression and reduced metastasis.

# publications[].publisher
American Society for Cell Biology (ASCB)

# publications[].label
Midbrain-Hindbrain Boundary Morphogenesis: At the Intersection of Wnt and Fgf Signaling.

# publications[].label
Quantifiable Intravital Light Sheet Microscopy.

# publications[].label
Dynamic multicomponent engineered tissue reorganization and matrix deposition measured with an integrated nonlinear optical microscopy-optical coherence microscopy system.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Analysis of the wnt1 regulatory chromosomal landscape.

# publications[].label
Broad-Spectrum Amino Acid Transporters ClAAP3 and ClAAP6 Expressed in Watermelon Fruits.

# publications[].label
Regulation and feedback of cholesterol metabolism

# publications[].label
Pipeline for fluorescent imaging and volumetric analysis of neurons in cleared mouse spinal cords.

# publications[].label
Combined lineage mapping and fate specification profiling with NLOM-OCM using sub-10-fs pulses

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Extended focal depth Fourier domain optical coherence microscopy with a Bessel-beam - LP02 mode - from a higher order mode fiber.

# publications[].label
Custom Imaging Chamber for Multimodal Volumetric Microscopy

# publications[].label
Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries.

# publications[].label
Ten simple rules for women principal investigators during a pandemic.

# publications[].label
The Sterol Trafficking Pathway in Arabidopsis thaliana.

# researcherOn[].label
Imaging enhancer-promoter interaction dynamics during embryonic brain development

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Neurological Disorders and Stroke

# streetAddress
Texas A&M University; Microscopy and Imaging Center; 2257 TAMU