# positions[].organizations[].parent[].label
College of Agriculture and Life Sciences

# overview
Dr. Ing's research interests focus on understanding how hormones regulate gene expression in animal tissues. Current research projects investigate the earliest days of pregnancy in the sheep uterus and the regulation of estrogen receptor gene expression, as well as stress hormone effects on gene expression in the stallion testes. Most recently, we have been studying the RNAs in sperm from stallions and honey bees in order to find a pattern consistent with high fertility.

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
Receptors, Vascular Endothelial Growth Factor

# keywords[]
Cyclic Nucleotide Phosphodiesterases, Type 3

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# educationAndTraining[].organization.label
University of Florida - (Gainesville, Florida, United States)

# educationAndTraining[].organization.label
University of Florida - (Gainesville, Florida, United States)

# educationAndTraining[].organization.label
University of Florida - (Gainesville, Florida, United States)

# awardsAndHonors[].label
Faculty Early Career Development (CAREER) Program

# awardsAndHonors[].label
College of Agriculture and Life Sciences Dean's Outstanding Achievement Award

# publications[].label
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).

# publications[].label
ESTROGEN UP-REGULATES EXPRESSION OF ITS RECEPTOR GENE IN SHEEP ENDOMETRIUM

# publications[].label
A progesterone-modulated, low-molecular-weight protein from the uterus of the sheep is associated with crystalline inclusion bodies in uterine epithelium and embryonic trophectoderm.

# publications[].label
Post-transcriptional effects of estrogens on gene expression: Messenger RNA stability and translation regulated by micrornas and other factors

# publications[].label
A rapid and sensitive reporter gene that uses green fluorescent protein expression to detect chemicals with estrogenic activity.

# publications[].label
Testicular germ cell apoptosis and formation of the sertoli cell barrier during the initiation of spermatogenesis in pubertal stallions

# publications[].label
Transcriptomic analysis of the honey bee (Apis mellifera) queen spermathecae reveals genes that may be involved in sperm storage after mating.

# publications[].label
Dexamethasone downregulates expression of several genes encoding orphan nuclear receptors that are important to steroidogenesis in stallion testes.

# publications[].label
Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAs.

# publications[].label
POST-TRANSCRIPTIONAL EFFECTS OF ESTROGENS ON GENE EXPRESSION: MESSENGER RNA STABILITY AND TRANSLATION REGULATED BY MICRORNAS AND OTHER FACTORS

# publications[].label
Oestradiol up-regulates oestrogen receptor, cyclophilin, and glyceraldehyde phosphate dehydrogenase mRNA concentrations in endometrium, but down-regulates them in liver.

# publications[].label
Glucocorticoids mediate the enhanced expression of intestinal type II arginase and argininosuccinate lyase in postweaning pigs.

# publications[].label
Myometrial effects of selective estrogen receptor modulators on estradiol-responsive gene expression are gene and cell-specific.

# publications[].label
Estradiol up-regulates estrogen receptor messenger ribonucleic acid in endometrial carcinoma (Ishikawa) cells by stabilizing the message.

# publications[].label
Temporal changes in histomorphology and gene expression in goat testes during postnatal development.

# publications[].label
Steroid hormones acutely regulate expression of a Nudix protein-encoding gene in the endometrial epithelium of sheep.

# publications[].label
Alpha(1-2)fucosyltransferase gene expression by caprine endometrial tissues obtained during the estrous cycle and early pregnancy.

# publications[].label
Estradiol up-regulates expression of a novel gene product involved in cell adhesion in the endometrial glands of sheep.

# publications[].label
The distribution of cells containing estrogen receptor-alpha (ERalpha) and ERbeta messenger ribonucleic acid in the preoptic area and hypothalamus of the sheep: comparison of males and females.

# publications[].label
Estrogen enhances endometrial estrogen receptor gene expression by a posttranscriptional mechanism in the ovariectomized ewe.

# publications[].label
AN EXPLANATION FOR THE ANTILUTEOLYTIC EFFECTS OF OVINE INTERFERON-TAU (0IFN-TAU)

# publications[].label
Multiple effects of transforming growth factor beta (TGF beta) on porcine trophectorderm adhesion.

# publications[].label
In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide.

# publications[].label
Cell-specific expression of estrogen-responsive genes in the uteri of cyclic, early pregnant and ovariectomized ewes.

# publications[].label
Characterization of sperm and androgen production by testes from control and ponazuril-treated stallions

# publications[].label
Post-transcriptional Regulation of Steroid Hormone Receptors

# publications[].label
Progesterone induction of the uterine milk proteins: major secretory proteins of sheep endometrium.

# publications[].label
Progestin exposure from birth: Epigenetic induction of a unique adult uterine phenotype in sheep - A glandless endometrium.

# publications[].label
Estradiol stabilizes estrogen receptor messenger ribonucleic acid in sheep endometrium via discrete sequence elements in its 3'-untranslated region.

# publications[].label
Effects of novel antiestrogens on expression of estrogen-responsive genes in the endometrium of the ovariectomized ewes.

# publications[].label
OVINE INTERFERON-TAU (OIFN-TAU) REGULATES ENDOMETRIAL ESTROGEN-RECEPTOR (ER) AND OXYTOCIN RECEPTOR (OTR) GENE-TRANSCRIPTION

# publications[].label
Beta transforming growth factors (TGFss) at the porcine conceptus-maternal interface. Part I: expression of TGFbeta1, TGFbeta2, and TGFbeta3 messenger ribonucleic acids.

# publications[].label
Estradiol up-regulates estrogen receptor and progesterone receptor gene expression in specific ovine uterine cells.

# publications[].label
Estradiol up-regulates estrogen receptor-alpha messenger ribonucleic acid in sheep endometrium by increasing its stability.

# publications[].label
ICI 182,780 acts as a partial agonist and antagonist of estradiol effects in specific cells of the sheep uterus.

# publications[].label
Estradiol up-regulates expression of the A + U-rich binding factor 1 (AUF1) gene in the sheep uterus.

# publications[].label
Biochemical characterization and biosynthesis of the uterine milk proteins of the pregnant sheep uterus.

# publications[].label
Endometrial effects of selective estrogen receptor modulators (SERMs) on estradiol-responsive gene expression are gene and cell-specific.

# publications[].label
Enhanced mRNA levels for intestinal type II arginase (ARG II), argininosuccinate synthase (ASS) and lyase (ASL) in postweaning pigs.

# publications[].label
Estradiol stabilizes estrogen receptor messenger RNA in sheep endometrium via discrete sequence elements in its 3 ' untranslated region.

# publications[].label
Temporal changes in histomorphology and gene expression in goat testes during postnatal development

# publications[].label
Three splice variants of keratinocyte growth factor receptor (KGFR) mRNA are expressed in the pig endometrium and fetal skin.

# publications[].label
CatSper and the relationship of hyperactivated motility to intracellular calcium and pH kinetics in equine sperm.

# publications[].label
The major progesterone-modulated proteins secreted into the sheep uterus are members of the serpin superfamily of serine protease inhibitors.

# publications[].label
Upregulation of antioxidant genes in the spermathecae of honey bee (Apis mellifera) queens after mating

# publications[].label
Anatomy and Physiology of the Male Reproductive System and Potential Targets of Toxicants

# publications[].label
Estradiol stabilizes estrogen receptor messenger RNA in sheep endometrium.

# publications[].label
Induction of c-fos, and cytochrome c oxidase subunits I and II by gossypol acetic acid in rat liver cells.

# publications[].label
Heat shock protein 70 gene expression in equine blastocysts after exposure of oocytes to high temperatures in vitro or in vivo after exercise of donor mares.

# publications[].label
Elevated Mating Frequency in Honey Bee (Hymenoptera: Apidae) Queens Exposed to the Miticide Amitraz During Development

# publications[].label
Transforming growth factor beta (TGFB) signaling is activated during porcine implantation: proposed role for latency-associated peptide interactions with integrins at the conceptus-maternal interface.

# publications[].label
Estradiol and a selective estrogen receptor modulator affect steroid hormone receptor messenger RNA levels and turnover in explant cultures of sheep endometrium.

# publications[].label
Identification and quantification of coding and long non-coding RNAs in stallion spermatozoa separated by density.

# publications[].label
Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat.

# publications[].label
Functional effects of transforming growth factor beta on adhesive properties of porcine trophectoderm.

# publications[].label
Marinobufagenin regulates permeability and gene expression of brain endothelial cells.

# publications[].label
Regulation of endometrial connexin43 by estrogen and progesterone in mares.

# publications[].label
Integrated analysis of microRNA expression and mRNA transcriptome in lungs of avian influenza virus infected broilers.

# publications[].label
Production and characterization of agonistic monoclonal antibodies against chicken CD40.

# publications[].label
DNA microarray analysis of gene expression in testicular tissue of stallions

# publications[].label
Characterization of equine GST A3-3 as a steroid isomerase.

# publications[].label
Synergism between steroid response and promoter elements during cell-free transcription.

# publications[].label
The COUP-TFs compose a family of functionally related transcription factors.

# publications[].label
The effects of estradiol and selective estrogen receptor modulators on gene expression and messenger RNA stability in immortalized sheep endometrial stromal cells and human endometrial adenocarcinoma cells.

# publications[].label
In vitro culture of precision-cut testicular tissue as a novel tool for the study of responses to LH.

# publications[].label
Gene expression in the spermatogenically inactive "dark" and maturing "light" testicular tissues of the prepubertal colt.

# publications[].label
Post-transcriptional effects of estrogens on gene expression: Messenger RNA stability and translation regulated by micrornas and other factors

# publications[].label
Fucosyltransferase gene expression in goat endometrium during the estrous cycle and early pregnancy.

# publications[].label
Tamoxifen up-regulates oestrogen receptor-alpha, c-fos and glyceraldehyde 3-phosphate-dehydrogenase mRNAs in ovine endometrium.

# publications[].label
Expression of beta transforming growth factors (TGF beta s) in the porcine peri-implantation uterus.

# publications[].label
Intrauterine infusion of latency-associated peptide (LAP) during early porcine pregnancy affects conceptus elongation and placental size.

# publications[].label
Dexamethasone acutely regulates endocrine parameters in stallions and subsequently affects gene expression in testicular germ cells.

# publications[].label
Intrauterine injection of ovine interferon-tau alters oestrogen receptor and oxytocin receptor expression in the endometrium of cyclic ewes.

# publications[].label
The distribution of progesterone receptor immunoreactivity and mRNA in the preoptic area and hypothalamus of the ewe: upregulation of progesterone receptor mRNA in the mediobasal hypothalamus by oestrogen.

# publications[].label
Estradiol up-regulates AUF1p45 binding to stabilizing regions within the 3'-untranslated region of estrogen receptor alpha mRNA.

# publications[].label
Dexamethasone acutely down-regulates genes involved in steroidogenesis in stallion testes.

# publications[].label
Dense spermatozoa in stallion ejaculates contain lower concentrations of mRNAs encoding the sperm specific calcium channel 1, ornithine decarboxylase antizyme 3, aromatase, and estrogen receptor alpha than less dense spermatozoa.

# publications[].label
Estrogen receptor alpha levels in rats consuming wheat bran and injected with azoxymethane

# publications[].label
Estrogen and progesterone receptors in peri-implantation porcine conceptuses.

# publications[].label
Pesticide Exposure During Development Does Not Affect the Larval Pheromones, Feeding Rates, or Morphology of Adult Honey Bee (Apis mellifera) Queens

# publications[].label
Effect of dexamethasone on serum and testicular concentrations of testosterone in stallions

# researcherOn[].label
Gene Expression Pathways in Reproductive Tissues

# researcherOn[].awardedBy.label
National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Queen Superedure in Honey Bees: How Do Agricultural Pesticides Impair Fertility in Queens and Drones?

# researcherOn[].awardedBy.label
United States Department of Agriculture - (Washington D.C., District of Columbia, United States)

# researcherOn[].awardedBy.preferredLabel
USDA-National Institute of Food And Agriculture

# streetAddress
Texas A&M University; Animal Science; 2471 TAMU

# schools[]
College of Agriculture and Life Sciences

# etdChairOf[].label
Laughlin, Andy M. (2011-08). Gene Expression in the Stallion Testes. Doctoral Dissertation.

# etdChairOf[].label
Faucette, Azure (2012-07). Changes in Gene Expression of Goat Developing Testes and Sperm During Breeding and Non-breeding Season. Doctoral Dissertation.

# etdChairOf[].label
Peer, Shawna Marie (2015-05). Characterization of GSTA3 Gene Products in Multiple Species and Demonstration of their Conservation in Divergent Species. Master's Thesis.