# positions[].organizations[].parent[].label
Texas A&M University Naresh K. Vashisht College of Medicine

# overview
My lab has had a number of research projects focusing on the study of lymphatic structure and function. Each of these projects has, as one of their objectives, the evaluation of the mechanisms (molecular, cellular, mechanical and tissue-level) regulating different aspects of lymphatic function. These projects focus on the ionic/calcium, contractile/regulatory proteins, molecular pathways that regulate lymph transport, lymphatic muscle function, the role of lymphatic function in the generation and resolution of tissue inflammation and the interactions between immune cells and the lymphatic cells. To support this work we have established cultured cell lines of both endothelial and muscle isolated from microlymphatics, acute and cultured isolated microlymphatic tissues, methodologies to evaluate lymphatic function at the single vessel, whole tissue and animal levels, methodologies to target cell-specific gene manipulation in isolated lymphatic tissues, approaches to microscopically image and model lymphatic network structure and function in 3D in lab animals. We have also evaluated the effects of space flight, various inflammatory mediators and other immune activation processes on lymphatic contractile and transport function and how these affect immunity. Finally, we have evaluated different types of lymphatic pathology resulting in lymphedema, various inflammatory diseases and immune dysfunction.

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Calcium Release-activated Calcium Channel Protein 1 (orai1)

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Platelet Endothelial Cell Adhesion Molecule-1

# keywords[]
Platelet Endothelial Cell Adhesion Molecule-1

# keywords[]
Vascular Endothelial Growth Factor Receptor-3

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Receptors, Vascular Endothelial Growth Factor

# keywords[]
Vascular Endothelial Growth Factor Receptor-3

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Calcium Release Activated Calcium Channels

# keywords[]
Vascular Endothelial Growth Factor Receptor-3

# keywords[]
Single-Strand Specific DNA And RNA Endonucleases

# keywords[]
Pregnancy And Preeclamsia Marinobufagenin Angiogenic Factors

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Cyclic GMP-Dependent Protein Kinase Type I

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Atp Binding Cassette Transporter, Subfamily B

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
5 Development Of Treatments And Therapeutic Interventions

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Preterm, Low Birth Weight And Health Of The Newborn

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Clinical Trials And Supportive Activities

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# keywords[]
Snake Venom Cysteine-rich Secretory Protein (svcrisp)

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
Interleukin 1 Receptor Antagonist Protein

# keywords[]
Prorenin And Its Receptor Pregnancy Preeclamsia

# keywords[]
Vascular Endothelial Growth Factor Receptor-1

# keywords[]
Vascular Endothelial Growth Factor Receptor-1

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Perinatal Period - Conditions Originating In Perinatal Period

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

# educationAndTraining[].organization.label
Medical College of Wisconsin - (Milwaukee, Wisconsin, United States)

# educationAndTraining[].field
Biology, Chemistry and Population Dynamics

# awardsAndHonors[].label
Medicine in the Institute of Microcirculation

# publications[].label
Borrelia burgdorferi adhere to blood vessels in the dura mater and are associated with increased meningeal T cells during murine disseminated borreliosis.

# publications[].label
DSS-induced colitis produces inflammation-induced bone loss while irisin treatment mitigates the inflammatory state in both gut and bone.

# publications[].label
Part 1: New Tools for Lymphatic Investigation

# publications[].label
Suppression of aldosterone and progesterone in preeclampsia.

# publications[].label
Protein Kinase C-Dependent Calcium Sensitization of Permeabilized Rat Lymphatic Muscle

# publications[].label
CONTRACTILE PROPERTIES OF MESENTERIC COLLECTING LYMPHATICS DURING PERIODS OF ENHANCED LYMPH-FLOW

# publications[].label
Molecular and cellular basis of myocardial angiogenesis.

# publications[].label
Thermal effects of MR imaging: worst-case studies on sheep.

# publications[].label
HISTAMINE INCREASES CORONARY VENULAR PERMEABILITY BY PHOSPHOLIPASE C-DEPENDENT SYNTHESIS OF NITRIC-OXIDE

# publications[].label
B7-33 NORMALIZES BLOOD PRESSURE IN THE REDUCED UTERINE PERFUSION PRESSURE RAT MODEL OF PREECLAMPSIA

# publications[].label
Differential Effects of In Vitro Treatment with Cinobufotalin on Three Types of Ovarian Cancer Cells.

# publications[].label
Length-tension relationships of small arteries, veins, and lymphatics from the rat mesenteric microcirculation.

# publications[].label
Permeability to albumin in isolated coronary venules.

# publications[].label
Abstract P173: Serum Soluble and Placental (Pro)Renin Receptor in Normal and Preeclamptic Pregnancy

# publications[].label
Visualization and comparison of vascular endothelial growth factor receptors in human umbilical vein and rat mesenteric lymphatic endothelial cells.

# publications[].label
Imposed flow-dependent inhibition in rat thoracic duct is not dependent from on K channel blockade

# publications[].label
DEVELOPING COMPUTATIONAL FLOW MODELS FOR THE LYMPHATIC VASCULATURE

# publications[].label
Burn Injury-Associated MHCII+ Immune Cell Accumulation Around Lymphatic Vessels of the Mesentery and Increased Lymphatic Endothelial Permeability Are Blocked by Doxycycline Treatment.

# publications[].label
IL-1 reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E2.

# publications[].label
Macrophage alterations within the mesenteric lymphatic tissue are associated with impairment of lymphatic pump in metabolic syndrome.

# publications[].label
Engineered biomimetic nanovesicles show intrinsic anti-inflammatory properties for the treatment of inflammatory bowel diseases.

# publications[].label
Cardiotonic steroids cause monolayer hyperpermeability in lymphatic endothelial cells via nitric oxide dependent pathway

# publications[].label
The Morphological Mapping of Mesenteric Lymphatic Network

# publications[].label
Increased susceptibility of aging kidney to ischemic injury: identification of candidate genes changed during aging, but corrected by caloric restriction.

# publications[].label
COMPARISON OF CINOBUFATALIN INDUCED APOPTOTIC SIGNALING IN THREE DIFFERENT OVARIAN CANCER CELL LINES

# publications[].label
A RESIDENT POPULATION OF APC WITHIN THE MUSCULARIZED VESSEL WALLS OF THE RAT LYMPHATIC NETWORK

# publications[].label
Length-dependence of lymphatic phasic contractile activity under isometric and isobaric conditions.

# publications[].label
Intrinsic increase in lymphangion muscle contractility in response to elevated afterload.

# publications[].label
Spaceflight influences gene expression, photoreceptor integrity, and oxidative stress-related damage in the murine retina.

# publications[].label
HYPERGLYCEMIA INDUCES AN ANTI-ANGIOGENIC MILIEU IN FIRST TRIMESTER CYTOTROPHOBLAST CELL

# publications[].label
Methods for continuous monitoring of water, electrolyte and food balance in rats

# publications[].label
Altered rodent gait characteristics after ~35 days in orbit aboard the International Space Station.

# publications[].label
Lymph transport in rat mesenteric lymphatics experiencing edemagenic stress (LB851)

# publications[].label
Variations in rat mesenteric tissue thickness due to microvasculature.

# publications[].label
Stromal interaction molecule 1 (STIM1) and Orai1 mediate histamine-evoked calcium entry and nuclear factor of activated T-cells (NFAT) signaling in human umbilical vein endothelial cells.

# publications[].label
Effect of Cinobufotalin on Three Different Ovarian Cancer Cell Lines

# publications[].label
L-NAME ATTENUATES THE CARDIOTONIC STEROIDS-INDUCED MONOLAYER PERMEABILITY IN LYMPHATIC ENDOTHELIAL CELLS

# publications[].label
Differential effects of myosin light chain kinase inhibition on contractility, force development and myosin light chain 20 phosphorylation of rat cervical and thoracic duct lymphatics.

# publications[].label
Calcium entry, mobilization, and extrusion in postcapillary venular endothelium exposed to bradykinin.

# publications[].label
Molecular and functional analyses of the contractile apparatus in lymphatic muscle.

# publications[].label
Effects of substance P on mesenteric lymphatic contractility in the rat.

# publications[].label
Erratum to Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development [Tissue & Cell 35 (2) (2003) 133142]

# publications[].label
Histamine-mediated regulatory loop in mesenteric perilymphatic mast cells

# publications[].label
Differential Mechanism of Action of 3,4',7-O-trimethylquercetin in Three Types of Ovarian Cancer Cells.

# publications[].label
Influence of low density lipoprotein (LDL) and oxidized LDL (oxLDL) on rat mesenteric lymphatic pumping-

# publications[].label
Electrophysiological properties of rat mesenteric lymphatic vessels and their regulation by stretch.

# publications[].label
Inhibition of the active lymph pump in rat mesenteric lymphatics by hydrogen peroxide.

# publications[].label
Lymphatic valve lock in response to modest gravitational loads: a contributing mechanism to peripheral lymphedema?

# publications[].label
EFFECTS OF EDEMAGENIC STRESS ON LYMPH TRANSPORT IN THE RAT MESENTERY

# publications[].label
Characterization of intact mesenteric lymphatic pump and its responsiveness to acute edemagenic stress.

# publications[].label
Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations.

# publications[].label
Flow mediated inhibition of the lymph pump in isolated rat microlymphatics.

# publications[].label
L-NAME Attenuates the Cardiotonic Steroids-induced Monolayer Permeability in Lymphatic Endothelial Cells

# publications[].label
ANTI-MARINOBUFAGENIN ANTIBODY ATTENUATES THE PREECLAMPSIA SYNDROME IN DOCA MODEL OF PREECLAMPSIA

# publications[].label
Development and characterization of endothelial cells from rat microlymphatics.

# publications[].label
Stretch-induced increases in intracellular calcium of isolated vascular smooth muscle cells.

# publications[].label
Regional heterogeneity of length-tension relationships in rat lymph vessels.

# publications[].label
Abstract P088: Pravastatin Protects Against Glucose-induced Anti-proliferative, Anti-invasive and Anti-angiogenic Milieu in Cytotrophoblasts

# publications[].label
ID: 105: COMPARISON OF PLACENTAL AND PLASMA SOLUBLE (PRO)RENIN RECEPTOR IN NORMAL AND PREECLAMPTIC PREGNANCY

# publications[].label
Image correlation algorithm for measuring lymphocyte velocity and diameter changes in contracting microlymphatics.

# publications[].label
SUPPRESSION OF ALDOSTERONE AND PROGESTERONE IN PREECLAMPSIA: PATIENTS AND A RAT MODEL STUDIES

# publications[].label
Evaluation of rat lymphatic muscle cell transcriptome by comparative oligonucleoticle array analysis

# publications[].label
Cartiotonic steroids affect monolayer permeability in lymphatic endothelial cells.

# publications[].label
Mechanical feedback mechanisms in a multiscale sliding filament model of lymphatic muscle pumping

# publications[].label
Microlymphatic flow using fast video microscopy

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Lymphatic contractions: The role of distension mechanisms.

# publications[].label
A multiscale sliding filament model of lymphatic muscle pumping.

# publications[].label
Aqueous humor outflow: what do we know? Where will it lead us?

# publications[].publisher
Association for Research in Vision and Ophthalmology (ARVO)

# publications[].label
MicroRNA signature of inflamed lymphatic endothelium and role of miR-9 in lymphangiogenesis and inflammation.

# publications[].label
Passive pressure-diameter relationship and structural composition of rat mesenteric lymphangions.

# publications[].label
Integrated geometric and mechanical analysis of an image-based lymphatic valve.

# publications[].label
Shear stress-induced gene response in human microvascular lymphatic endothelial cells

# publications[].label
Impact of Dynamic Transmural Pressure on Lymph Propulsion in Lymphatic Vessels

# publications[].label
A bioreactor for in vitro studies of lymphatic endothelial cells with simultaneous fluid shear stress and membrane strain.

# publications[].label
Effect of the snake venom component crotamine on lymphatic endothelial cell responses and lymph transport.

# publications[].label
Application of 3D optical sectioning microscopy to the study of microvascular biology

# publications[].label
Immune cell mediated regulation of lymphatic contractility during inflammation

# publications[].label
LPS mediated decreases in immune cells recruitment on or near lymphatics impairs lymphatic contractility

# publications[].label
Modeling strategies for optimizing lymph flow

# publications[].label
IN VITRO ANTI-METASTATIC ACTIVITY OF CINOBUFOTALIN IN SK-OV-3, CRL-1978 AND CRL-11731 OVARIAN CANCER CELL LINES

# publications[].label
Molecular profile and proliferative responses of rat lymphatic endothelial cells in culture.

# publications[].label
Independent and interactive effects of preload and afterload on the pump function of the isolated lymphangion.

# publications[].label
NOVEL PEPTIDE B7-33 AND RELAXIN HORMONES PROTECT CYTOTROPHOBLASTS FROM PREECLAMPSIA PHENOTYPE

# publications[].label
Sa1502  Knockout (KO) of the Melatonin Receptor, Mt2, Enhances Alcohol-Induced Ductular Reaction (DR), Biliary Senescence and Hepatic Fibrosis During Alcoholic Liver Disease (ALD)

# publications[].label
Evaluating the time-varying elastance concept for lymphangions

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
Lymphatic muscle: a review of contractile function.

# publications[].label
Hyperglycemia induces apoptotic signaling in first trimester cytotrophoblast cells (1010.6)

# publications[].label
Inhibition of myosin light chain phosphorylation decreases rat mesenteric lymphatic contractile activity.

# publications[].label
3,4 ',7-O-Trimethylquercetin as a Novel Agent to Inhibit in Vitro Ovarian Cancer Cell Migration and Invasion

# publications[].label
Abstract 066: Decoy Peptide Attenuates The Syndrome Of preeclampsia In A Rodent Model

# publications[].label
Lymph protein concentration in initial and collecting lymphatics of the rat.

# publications[].label
Specific inhibition of eNOS through protein transfection in intact Isolated microvessels

# publications[].label
Fast Imaging System and Algorithm for Monitoring Microlymphatics

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Hypoxia and extracellular matrix proteins influence angiogenesis and lymphangiogenesis in mouse embryoid bodies.

# publications[].label
RELAXIN LIKE PEPTIDE B7-33 AND IT'S DERIVATIVES DEMONSTRATE EFFICACY IN RODENT MODELS OF PREECLAMPSIA

# publications[].label
Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents.

# publications[].label
Effect of Cardiotonic Steroids on Monolayer Permeability and Junction Proteins in Lymphatic Endothelial Cells

# publications[].label
Analysis of Lymphatic Vessel Formation by Whole-Mount Immunofluorescence Staining.

# publications[].label
Progressive Collecting Liver Lymphatic Vessels Dysfunction over the Course of Extrahepatic Cholestasis

# publications[].label
Colonic Insult Impairs Lymph Flow, Increases Cellular Content of the Lymph, Alters Local Lymphatic Microenvironment, and Leads to Sustained Inflammation in the Rat Ileum.

# publications[].label
Aging-related changes in lymphatic collectors predispose to pathogen dissemination in tissues

# publications[].publisher
The American Association of Immunologists

# publications[].label
Construction of an optical bench microscope for intravital studies.

# publications[].label
Low density lipoprotein modulates rat mesenteric lymphatic pumping

# publications[].label
ENDOTHELIAL-CELL HETEROGENEITY AND CALCIUM AS MEASURED IN INTACT ISOLATED ARTERIOLES

# publications[].label
The Role of Lymphatics in Cholestasis: A Comprehensive Review.

# publications[].label
CINOBUFOTALIN HINDERS CYTOTROPHOBLASTS FUNCTION VIA CELL CYCLE ARREST

# publications[].label
CINOBUFOTALIN AS A NOVEL AGENT TO INHIBIT IN-VITRO EPITHELIAL OVARIAN CANCER CELL PROLIFERATION, MIGRATION AND INVASION

# publications[].label
Nitric Oxide Transport in Lymphatic Vessels

# publications[].label
Hydrodynamic regulation of lymphatic transport and the impact of aging.

# publications[].label
Modeling Lymph Flow and Fluid Exchange with Blood Vessels in Lymph Nodes.

# publications[].label
Effect of Rapamycin on Contractility of Lymphatic Vessel and Energy Metabolism of Lymphatic Muscle Cells

# publications[].label
MARINOBUFAGENIN-INDUCED ANTI-ANGIOGENIC MILIEU IN CYTOTROPHOBLASTS IS ATTENUATED BY NOVEL ANTI-MBG ANTIBODIES

# publications[].label
Development of siRNA strategy to knockdown the regulatory contractile proteins in lymphatic muscle

# publications[].label
Adenovirus-mediated gene transfection in the isolated lymphatic vessels.

# publications[].label
Contraction-initiated NO-dependent lymphatic relaxation: a self-regulatory mechanism in rat thoracic duct.

# publications[].label
Calcium measurement in isolated arterioles during myogenic and agonist stimulation.

# publications[].label
3,4',7-O-trimethylquercetin Inhibits Invasion and Migration of Ovarian Cancer Cells.

# publications[].label
Inflammatory state of lymphatic vessels and miRNA profiles associated with relapse in ovarian cancer patients

# publications[].label
A single-chain derivative of the relaxin hormone (b7-33) protects cytotrophoblasts from hyperglycemia-induced preeclampsia phenotype and induces the survival pathway

# publications[].label
A bufadienolide suppresses aldosterone availability in preeclampsia: a translational approach with in vivo, in vitro, and patient study

# publications[].label
A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Ca2+ release-activated Ca2+ channels are responsible for histamine-induced Ca2+ entry, permeability increase, and interleukin synthesis in lymphatic endothelial cells.

# publications[].label
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1.

# publications[].label
Venomotion modulates lymphatic pumping in the bat wing.

# publications[].label
CARDIOTONIC STEROIDS TRIGGER CYTOTROPHOBLAST DYSFUNCTION VIA CELL CYCLE ARREST AND APOPTOTIC SIGNALING

# publications[].label
Lipopolysaccharide modulates neutrophil recruitment and macrophage polarization on lymphatic vessels and impairs lymphatic function in rat mesentery.

# publications[].label
EFFECTS OF NG-MONOMETHYL-L-ARGININE ON THE CONTRACTILE ACTIVITY OF RAT MESENTERIC LYMPHATICS

# publications[].label
Upregulated expression of immune function genes in rat lymphatic vessels

# publications[].label
Changes in end-to-end interactions of tropomyosin affect mouse cardiac muscle dynamics.

# publications[].label
Phasic contractions of rat mesenteric lymphatics increase basal and phasic nitric oxide generation in vivo.

# publications[].label
Effect of the non-peptide blocker (+/-) CP 96,345 on the cellular mechanism involved in the response to NK1 receptor stimulation in human skin fibroblasts.

# publications[].label
Hydrodynamic regulation of lymphatic vessel transport function and the impact of aging

# publications[].label
Comparison of Urinary Levels of Marinobufagenin and Angiogenic Factors Between Preeclamptic and Normally Pregnant Patients

# publications[].label
Histamine-mediated autocrine signaling in mesenteric perilymphatic mast cells.

# publications[].label
Apoptotic and stress signaling markers are augmented in preeclamptic placenta and umbilical cord.

# publications[].label
Role of cinobufotalin in the pathogenesis of preeclampsia: in vivo and in vitro studies

# publications[].label
Liver fibrosis and biliary proliferation are enhanced in the rat model of inflammatory bowel disease

# publications[].label
Image correlation method for measuring flow and diameter changes in contracting mesenteric microlymphatics in situ

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Abstract 15945: Cdc42 is Required for Lymphatic Branching, Maturation and Valve Formation During Development

# publications[].label
Quantifying Lymphatic Endothelial Cell Morphological Changes in Response to Fluid Shear Stress, Cyclic Strain, or Combined Stress and Strain In Vitro

# publications[].label
Lymphangion-chip: a microphysiological system which supports co-culture and bidirectional signaling of lymphatic endothelial and muscle cells.

# publications[].label
Hyperglycemia down-regulates cGMP-dependent protein kinase I expression in first trimester cytotrophoblast cells.

# publications[].label
Interaction of neutrophils and endothelium in isolated coronary venules and arterioles.

# publications[].label
Microelectrophoresis of lymph and plasma from rat mesenteric microcirculation

# publications[].label
Impairments in the intrinsic contractility of mesenteric collecting lymphatics in a rat model of metabolic syndrome.

# publications[].label
ROLE OF CARDIOTONIC STEROIDS IN PREECLAMPSIA: A TRANSLATIONAL APPROACH WITH IN VIVO, IN VITRO, AND PATIENT STUDIES

# publications[].label
A CARDIOTONIC STEROID CAUSES CEREBRAL VASCULAR LEAK SYNDROME IN HYPERTENSION DURING PREGNANCY: A TRANSLATIONAL APPROACH

# publications[].label
PRAVASTATIN PROTECTS A SW-71 CYTOTROPHOBLAST CELL LINE FROM A HYPERGLYCEMIA-INDUCED PREECLAMPSIA PHENOTYPE

# publications[].label
Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance.

# publications[].label
DEVELOPING A MODEL FOR MASS TRANSPORT OF NITRIC OXIDE IN THE LYMPHATIC SYSTEM

# publications[].label
Reactive oxygen metabolites inhibit spontaneous lymphatic contractions.

# publications[].label
DIABETES AND PRE-ECLAMPSIA: A RETROSPECTIVE CROSS-SECTIONAL STUDY OF PREGNANCY OUTCOMES

# publications[].label
Lymph flow, shear stress, and lymphocyte velocity in rat mesenteric prenodal lymphatics.

# publications[].label
Dichotomous effects on lymphatic transport with loss of caveolae in mice.

# publications[].label
A moderately elevated soy protein diet mitigates inflammatory changes in gut and in bone turnover during chronic TNBS-induced inflammatory bowel disease.

# publications[].label
MECHANISM OF THE BRADYKININ-INDUCED [CA-2+]1 RESPONSE IN CORONARY VENULAR ENDOTHELIAL-CELLS

# publications[].label
Regulation of lymphatic contractility by myosin light chain phosphorylation

# publications[].label
Sensitivity of Mouse Small Intestinal Immune Tissue Architecture

# publications[].label
Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.

# publications[].label
A bufadienolide causes cerebral vascular leak syndrome in preeclampsia: in vivo and in vitro study

# publications[].label
Demonstration and Analysis of the Suction Effect for Pumping Lymph from Tissue Beds at Subatmospheric Pressure.

# publications[].label
Blunted flow-mediated responses and diminished nitric oxide synthase expression in lymphatic thoracic ducts of a rat model of metabolic syndrome.

# publications[].label
Molecular and cellular characterization of lymphatic muscle.

# publications[].label
The Morphological Mapping of Mesenteric Lymphatic Network

# publications[].label
Differential Muscle Cell Recruitments and Functions in Mouse Lymphatic Tissue Beds

# publications[].label
Shortening velocities of rat mesenteric lymphatics during spontaneous and agonist-induced contractions

# publications[].label
Relationship between cardiac protein tyrosine phosphorylation and myofibrillogenesis during axolotl heart development.

# publications[].label
Effect of Cinobufotalin on Three Different Ovarian Cancer Cell Lines

# publications[].label
Physiology and pathobiology of the microcirculation.

# publications[].label
EXOGENOUS NITRIC OXIDE (NO) MODULATES THE GPROTEIN COUPLED SIGNALING PROTEINS IN CULTURED LYMPHATIC SMOOTH MUSCLE CELLS

# publications[].label
Development of a cultured lymphatic muscle cell line from rat cervical duct

# publications[].label
Flow-mediated NO production in the endothelium is dependent on eNOS activity and shear

# publications[].label
Effects of Creactive protein on rat mesenteric lymphatic contractility

# publications[].label
Effects of dynamic shear and transmural pressure on wall shear stress sensitivity in collecting lymphatic vessels.

# publications[].label
Force-velocity relationships of rat mesenteric lymphatics and arteries

# publications[].label
Quantitative Profiling of the Lymph Node Clearance Capacity.

# publications[].label
Protein transfection of intact microvessels specifically modulates vasoreactivity and permeability.

# publications[].label
Inflammatory state of lymphatic vessels and miRNA profiles associated with relapse in ovarian cancer patients.

# publications[].label
Loss of Caveolin-1 Increases Macromolecule Transport Across Lymphatic Endothelium

# publications[].label
Network Scale Modeling of Lymph Transport and Its Effective Pumping Parameters.

# publications[].label
A Novel Computational Model Predicts Key Regulators of Chemokine Gradient Formation in Lymph Nodes and Site-Specific Roles for CCL19 and ACKR4

# publications[].label
DEVELOPMENT OF AN INVITRO MODEL OF CORONARY VENULAR EXCHANGE

# publications[].label
Pressure-volume relationships of rat mesenteric lymphatic vessels in response to controlled preload and afterload steps

# publications[].label
Junctional localization of occcludin and N-cadherin in rat mesenteric microlymphatic endothelial cells.

# publications[].label
Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells.

# publications[].publisher
The American Association of Immunologists

# publications[].label
VALIDATION OF QUASI-STEADY ANALYSIS FOR LYMPHATIC FLUID FLOW AND MASS TRANSPORT

# publications[].label
Automated measurement of diameter and contraction waves of cannulated lymphatic microvessels.

# publications[].label
Abstract 314: Elevation of (pro)renin and Its Receptor in Preeclampsia: A Rat Model and Human Patients

# publications[].label
Heterogeneous production and influences of NO along the lymphatic endothelium

# publications[].label
Physiology of human lymphatic contractility: a historical perspective.

# publications[].label
Molecular Mechanism of Substance P Mediated Signaling in Lymphatic System

# publications[].label
Oxygen radicals, enzymes, and fluid transport through pericardial interstitium.

# publications[].label
Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis.

# publications[].label
P060 INFLAMMATION-ASSOCIATED COLONIC LYMPHATIC ARCHITECTURE DISRUPTION IS AMELIORATED BY IRISIN A CHRONIC RODENT MODEL OF IBD

# publications[].label
Hyperglycemia Hinders First Trimester Cytotrophoblast Migration and Induces Apoptosis

# publications[].label
Histological characteristics of mouse diaphragm lymphatics and their functional significance

# publications[].label
ESTRADIOL IMPEDES FIRST TRIMESTER CYTOTROPHOBLASTS FUNCTION VIA ANTI-ANGIOGENIC AND APOPTOTIC SIGNALING

# publications[].label
Pathogenesis of pre-eclampsia: marinobufagenin and angiogenic imbalance as biomarkers of the syndrome.

# publications[].label
Mechanical properties of rat mesenteric lymphatic and arterial smooth muscle

# publications[].label
Multiple Ionic Mechanisms Activated by Bradykinin in Coronary Venular Endothelial Cells

# publications[].label
COORDINATION OF LYMPHATIC PUMPING - A THEORETICAL-MODEL

# publications[].label
Calcium sensitivity and cooperativity of permeabilized rat mesenteric lymphatics.

# publications[].label
Ocular And Jugular Gravitational Dose-Response Curves During Hypovolemia: Preliminary Results

# publications[].label
Increased Lymphatic Permeability During Shock and Burn Trauma Alters Antigen Presenting Cell Recruitment to Mesenteric Lymph Vessels

# publications[].label
Confocal image-based computational modeling of nitric oxide transport in a rat mesenteric lymphatic vessel.

# publications[].label
CULTURE OF LYMPHATIC VESSELS AND DEVELOPMENT OF TRANSFECTION TECHNIQUES TO TARGET GENES INVOLVED IN REGULATION OF LYMPHATIC CONTRACTILITY

# publications[].label
Detection of transient receptor potential channel expression in rat lymphatic vessels

# publications[].label
HETEROGENEOUS INTERACTION BETWEEN NEUTROPHILS AND ENDOTHELIUM IN ISOLATED CORONARY ARTERIOLES AND VENULES

# publications[].label
Modulation of lymphatic muscle contractility by the neuropeptide substance P.

# publications[].label
Maximum shortening velocity of lymphatic muscle approaches that of striated muscle.

# publications[].label
Abstract P426: Novel Peptide B7-33 Demonstrates Efficacy In Rat Models Of Preeclampsia

# publications[].label
Abstract P3042: Novel Peptide B7-33 and It's Lipidated Derivative Protect Cytotrophoblasts From Preeclampsia Phenotype in a Cellular Model of the Syndrome

# publications[].label
Inflammatory Bowel Disease in a Rodent Model Alters Osteocyte Protein Levels Controlling Bone Turnover.

# publications[].label
Sa1521  Dysfunction of Collecting Liver Lymphatics During the Progression of Extrahepatic Cholestasis

# publications[].label
PATHOPHYSIOLOGICAL CONSEQUENCES OF ATHEROSCLEROSIS ON CORONARY EXCHANGE VESSELS

# publications[].label
TRANSPORT OF LYMPH: MECHANISMS AND POTENTIAL FOR CORRECTION

# publications[].label
Comparative Analysis of Gastrointestinal and Bone Inflammation in Hindlimb Unloading

# publications[].label
Venomotion propels lymph in the pallid bat wing

# publications[].label
Aging-associated alterations in lymphatic vessels and mast cells in perilymphatic tissues

# publications[].label
Gutassociated lymphoid tissue, T cell trafficking, and chronic intestinal inflammation

# publications[].label
Metabolism and Aging: From Molecular Physiology to Systems Biology.

# publications[].label
Nitric Oxide Production By Contracting Rat Mesenteric Lymphatic Vessels Is Primarily Within Valvular Regions

# publications[].label
Determining the combined effect of the lymphatic valve leaflets and sinus on resistance to forward flow.

# publications[].label
Role of phospholipase C, protein kinase C, and calcium in VEGF-induced venular hyperpermeability.

# publications[].label
Characterization of proliferative responses of rat lymphatic endothelial cells RMLEC in vitro

# publications[].label
Role of tropomyosin and myosin binding protein C in force frequency relationship of cardiac muscle

# publications[].label
Temporal Dynamics of the Rat Thoracic Duct Contractility in the Presence of Imposed Flow.

# publications[].label
Lymphatic filariasis: perspectives on lymphatic remodeling and contractile dysfunction in filarial disease pathogenesis.

# publications[].label
Cinobufotalin Inhibits Ovarian Cancer Cells Proliferation, Migration and Invasion

# publications[].label
Detection of integrins on rat mesenteric lymphatic endothelial cells

# publications[].label
Roles of phosphorylation of myosin binding protein-C and troponin I in mouse cardiac muscle twitch dynamics.

# publications[].label
CINOBUFOTALIN INHIBITS OVARIAN CANCER CELL METASTASIS VIA APOPTOTIC SIGNALING AND TARGETING THE mTOR PATHWAY

# publications[].label
EVALUATION OF CELLULAR MECHANISMS BY WHICH CINOBUFOTALIN INHIBITS OVARIAN CANCER CELL LINES FUNCTION

# publications[].label
Microparticle image velocimetry approach to flow measurements in isolated contracting lymphatic vessels.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Mechanical and contractile characteristics of rat thoracic duct and cervical lymphatics

# publications[].label
Determinants of valve gating in collecting lymphatic vessels from rat mesentery.

# publications[].label
Abstract P176: Maternal and Neonatal Outcomes in Normal and Preeclamptic Pregnancies - A Comparative Prospective Study

# publications[].label
Measuring microlymphatic flow using fast video microscopy.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
HYPOXIA INDUCES THE STRESS AND APOPTOTIC SIGNALING IN CULTURED RAT LUNG MICROVASCULAR ENDOTHELIAL CELLS

# publications[].label
Aging-associated alterations in lymphatic vessels and mast cells in perilymphatic tissues

# publications[].publisher
The American Association of Immunologists

# publications[].label
CALCIUM REGULATION IN LYMPHATIC ENDOTHELIAL CELLS UNDER FLOW

# publications[].label
Effects of f-Met-Leu-Phe-induced inflammation on intestinal lymph flow and lymphatic pump behavior.

# publications[].label
URINARY LEVELS OF MARINOBUFAGENIN AND ANGIOGENIC FACTORS IN PREECLAMPTIC PATIENTS

# publications[].label
P035 EXOGENOUS ADMINISTRATION OF IRISIN DURING CHRONIC TNBS-INDUCED GUT INFLAMMATION REVERSES INFLAMMATION-INDUCED ALTERATIONS IN BONE TURNOVER

# publications[].label
Progressive dysfunction of collecting liver lymphatics during the development of extrahepatic cholestasis

# publications[].label
Charged residue alterations in the inner-core domain and carboxy-terminus of alpha-tropomyosin differentially affect mouse cardiac muscle contractility.

# publications[].label
Texas A&M university system program for excellence in life sciences: A new paradigm for lymphatic vessel research

# publications[].label
PKC activation increases Ca sensitivity of permeabilized lymphatic muscle via myosin light chain 20 phosphorylation-dependent and -independent mechanisms.

# publications[].label
Nitric oxide (NO) dependent cellular signaling in cultured lymphatic smooth muscle cells

# publications[].label
Nitric oxide formation by lymphatic bulb and valves is a major regulatory component of lymphatic pumping.

# publications[].label
CARDIOTONIC STEROIDS ALTER THE MONOLAYER PERMEABILITY AND JUNCTIONAL PROTEINS IN LYMPHATIC ENDOTHELIAL CELLS

# publications[].label
Molecular regulation of lymphatic contractility.

# publications[].label
Effects of different growth factors on migration of rat microlymphatic endothelial cells

# publications[].label
The effects of inflammatory cytokines on lymphatic endothelial barrier function.

# publications[].label
Ca2+-related proteins associated with intracellular stores in rat lymphatics

# publications[].label
Estimation of shear stress in contracting microlymphatic vessels

# publications[].label
Impairment of lymphatic endothelial barrier function by X-ray irradiation.

# publications[].label
Inhibition of the active lymph pump by flow in rat mesenteric lymphatics and thoracic duct.

# publications[].label
Abstract P154: Plasma and Placental (Pro)Renin and Soluble (Pro)Renin Receptor are Upregulated in Preeclamptic Pregnancy

# publications[].label
Phasic contractions responsible for an NO-dependent relaxation in rat thoracic duct

# publications[].label
Isolation of Lymphatic Muscle Cells (LMCs ) from Rat Mesentery.

# publications[].label
Analysis of picogram quantities of protein in subnanoliter-size samples.

# publications[].label
The isolation and characterization of a new snake venom cysteine-rich secretory protein (svCRiSP) from the venom of the Southern Pacific rattlesnake and its effect on vascular permeability.

# publications[].label
Inhibition of active lymph pump by simulated microgravity in rats.

# publications[].label
Microarray analyis of molecular adaptation of lymphatic vessels to high flow conditions

# publications[].label
CINOBUFATALIN IMPAIRS FIRST TRIMESTER CYTOTROPHOBLAST FUNCTIONS VIA CELL CYCLE ARREST AND APOPTOTIC SIGNALING

# publications[].label
Cdc42 is required for lymphatic branching, maturation and valve formation during embryonic development

# publications[].label
P060 INFLAMMATION-ASSOCIATED COLONIC LYMPHATIC ARCHITECTURE DISRUPTION IS AMELIORATED BY IRISIN A CHRONIC RODENT MODEL OF IBD

# publications[].label
IL-1β reduces cardiac lymphatic muscle contraction via COX-2 and PGE2 induction: Potential role in myocarditis.

# publications[].label
Substance P activates both contractile and inflammatory pathways in lymphatics through the neurokinin receptors NK1R and NK3R.

# publications[].label
Lymphatic Endothelial Cell Response to XRay Irradiation

# publications[].label
Lymphatic smooth muscle: the motor unit of lymph drainage.

# publications[].label
Lymphatic biology and the microcirculation: past, present and future.

# publications[].label
The roles of rapid changes in lymph flow direction and NO release in flow-mediated lymphatic responses.

# publications[].label
Involvement of Pro(Renin) and Its Receptor Associated Novel Renin Angiotensin System in Pathogenesis of Preeclampsia

# publications[].label
Hyperglycemia impairs cytotrophoblast function via stress signaling.

# publications[].label
Lymphatic Cannulation for Lymph Sampling and Molecular Delivery.

# publications[].publisher
The American Association of Immunologists

# publications[].label
Pulmonary air embolization inhibits lung lymph flow by increasing lymphatic outflow pressure.

# publications[].label
Mo1470  Secretin/Secretin Receptor Signaling Modulates Biliary Immunobiology and Subsequent T Cell Migration in Early Stage Primary Biliary Cholangitis (PBC)

# publications[].label
THE ROLE OF NITRIC-OXIDE IN HISTAMINE-INDUCED PERMEABILITY CHANGES IN ISOLATED CORONARY VENULES

# publications[].label
Effects of reactive oxygen metabolites on lymphatic pumping function

# publications[].label
Distribution, propagation, and coordination of contractile activity in lymphatics.

# publications[].label
[Contractions of the lymphangion under low filling conditions and the absence of stretching stimuli. The possibility of the sucking effect].

# publications[].label
Abstract 546: L-NAME Attenuates the Cardiotonic Steroids-induced Monolayer Permeability in Lymphatic Endothelial Cells

# publications[].label
Peptide B7-33, a Single-Chain Derivative of the Relaxin Hormone Protects Cytotrophoblasts from Marinobufagenin-Induced Preeclampsia Phenotype

# publications[].label
MARINOBUFAGENIN AND ANGIOGENIC IMBALANCE ARE THE INDICATORS OF CEREBRALVASCULAR LEAK SYNDROME IN PREECLAMPSIA

# publications[].label
CINOBUFOTALIN INHIBITS OVARIAN CANCER CELLS PROLIFERATION, MIGRATION AND INVASION

# publications[].label
COMPARISON OF 3,4 ',7-O-TRIMETHYLQUERCETIN INDUCED APOPTOTIC SIGNALING IN THREE OVARIAN CANCER CELL LINES

# publications[].label
Hypoxia Modulates the Cellular Signaling in Cultured Rat Lung Microvascular Endothelial Cells

# publications[].label
Inflammation-induced lymphatic architecture and bone turnover changes are ameliorated by irisin treatment in chronic inflammatory bowel disease.

# publications[].label
Aging-associated chronic mast cell activation by aged mesenteric lymphatic vessels

# publications[].publisher
The American Association of Immunologists

# publications[].label
NOVEL PEPTIDE B7-33, A SINGLE-CHAIN DERIVATIVE OF THE RELAXIN HORMONE, PROTECTS CYTOTROPHOBLASTS FROM ANTI-ANGIOGENIC MILIEU IN CELLULAR MODELS OF PREECLAMPSIA

# publications[].label
Functional Status of Perilymphatic Mast Cells is Critical for Lymphatic and Immune Functions

# publications[].label
Signaling pathways mediating VEGF165-induced calcium transients and membrane depolarization in human endothelial cells.

# publications[].label
Cadherin and catenin protein expression on rat mesenteric lymphatic endothelial cells

# publications[].label
Histamine increases venular permeability via a phospholipase C-NO synthase-guanylate cyclase cascade.

# publications[].label
Intracellular calcium dynamics of lymphatic endothelial and muscle cells co-cultured in a Lymphangion-Chip under pulsatile flow.

# publications[].label
Diminished mesenteric vaso- and venoconstriction and elevated plasma ANP and BNP with simulated microgravity.

# publications[].label
Cyclic guanosine monophosphate and the dependent protein kinase regulate lymphatic contractility in rat thoracic duct.

# publications[].label
Cinobufotalin impedes Sw.71 cytotrophoblast cell line function via cell cycle arrest and apoptotic signaling.

# publications[].label
Electrophysiology of rat mesenteric lymphatic vessel contraction

# publications[].label
Sa1520  Knockdown of Stimulator of Interferon Genes (STING) Reduces Biliary Senescence and Liver Inflammation and Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis (PSC)

# publications[].label
Comparison of outcomes between normal and preeclamptic pregnancies: a prospective study

# publications[].label
Role of myosin binding protein C phosphorylation in force frequency relationship of the heart

# publications[].label
Anti-MBG antibodies attenuate MBG-induced anti-proliferative and anti-angiogenic milieu in cytotrophoblast cell model

# publications[].label
P035 EXOGENOUS ADMINISTRATION OF IRISIN DURING CHRONIC TNBS-INDUCED GUT INFLAMMATION REVERSES INFLAMMATION-INDUCED ALTERATIONS IN BONE TURNOVER

# publications[].label
Acute exposure to space flight results in evidence of reduced lymph Transport, tissue fluid Shifts, and immune alterations in the rat gastrointestinal system.

# publications[].label
Effect of Crotalus oreganus Derived Crotamine on Lymphatic Endothelial Cells and Lymph Transport

# publications[].label
Lymphatic system: a vital link between metabolic syndrome and inflammation.

# publications[].label
Contractile behavior of the uterine lymphatic vessels

# publications[].label
Measurement of shear stress-mediated intracellular calcium dynamics in human dermal lymphatic endothelial cells.

# publications[].label
Rat mesenteric lymphatics undergo remodeling and have altered contractility and calcium sensitivity in a model of metabolic syndrome

# publications[].label
Reduced mitochondrial buffering of voltage-gated calcium influx in aged rat basal forebrain neurons.

# publications[].label
Measurements of protein concentrations in rat mesenteric lymph vessels

# publications[].label
Differential expression of thin filament regulatory proteins in rat lymphatics

# publications[].label
Microarray analysis of VEGF-C responsive genes in human lymphatic endothelial cells.

# publications[].label
Attenuation of hyperglycemia-induced apoptotic signaling and anti-angiogenic milieu in cultured cytotrophoblast cells.

# publications[].label
The role of brain and C-type natriuretic peptide in rat mesenteric lymphatics.

# publications[].label
CARDIOTONIC STERIODS INDUCE STRESS SIGNALING IN PREECLAMSIA: A TRANSLATIONAL APPROACH WITH IN VIVO, IN VITRO, AND PATIENT STUDIES

# publications[].label
Oxidized low-density lipoprotein inhibits nitric oxide-mediated coronary arteriolar dilation by up-regulating endothelial arginase I.

# publications[].label
KP-17 INHIBITS METASTATIC ACTIVITY IN MULTIPLE CANCER CELLS

# publications[].label
Targeting Lymphangiogenesis and Lymph Node Metastasis in Liver Cancer.

# publications[].label
Measuring contraction propagation and localizing pacemaker cells using high speed video microscopy.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
994 MARINOBUFAGENIN CAUSES CEREBRAL VASCULAR LEAK SYNDROME IN PREECLAMPSIA

# publications[].label
Abstract 315: Supression of Aldosterone and Progesterone in Preeclampsia: Role of Marinobufagenin: A Translational Approach

# publications[].label
Applying the time-varying elastance concept to determine the optimum coordination of lymphangion contraction in a lymphatic vessel

# publications[].publisher
Institute of Electrical and Electronics Engineers (IEEE)

# publications[].label
An automated method to control preload by compensation for stress relaxation in spontaneously contracting, isometric rat mesenteric lymphatics.

# publications[].label
Substance P activates both inflammatory and contractile signaling pathways in the lymphatics through neurokinin receptors

# publications[].label
FLOW MODULATES VENULAR PERMEABILITY BY A NITRIC OXIDE-RELATED MECHANISM

# publications[].label
Effects of hindlimb suspension on active pumping of rat thoracic duct and mesenteric lymphatics

# publications[].label
Flow modulates coronary venular permeability by a nitric oxide-related mechanism.

# publications[].label
Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices.

# publications[].label
783 UPREGULATION OF (PRO)RENIN AND ITS RECEPTOR IN PREECLAMPSIA

# publications[].label
Abstract P104: Neutralization Of Marinobufagenin Demonstrates Efficacy In Vitro And In Vivo In Models Of Preeclampsia

# publications[].label
PRE-CLINICAL EVALUATION OF CINOBUFOTALIN AS A POTENTIAL ANTI-OVARIAN CANCER AGENT

# publications[].label
Junctional molecule expression on rat microlymphatic endothelial cells

# publications[].label
Inhibition of myosin light chain phosphorylation decreases rat mesenteric lymphatic pump function

# publications[].label
An immunological fingerprint differentiates muscular lymphatics from arteries and veins.

# publications[].label
Rate-sensitive contractile responses of rat mesenteric lymphatics to circumferential stretch

# publications[].label
LPS induced changes in immune cell recruitment and impairment of lymphatic contractility during inflammation

# publications[].label
A METHYLQUERCETIN INHIBITS THE MIGRATION AND INVASION OF OVARIAN CANCER CELL

# publications[].label
Lymph transport in rat mesenteric lymphatics experiencing edemagenic stress.

# publications[].label
Quantification of the Whole Lymph Node Vasculature Based on Tomography of the Vessel Corrosion Casts.

# publications[].label
Characteristics of the active lymph pump in bovine prenodal mesenteric lymphatics.

# publications[].label
Intrinsic pump-conduit behavior of lymphangions.

# publications[].label
Mast Cells-Dependent Compromised Response of Aged Mesenteric Lymphatic Vessels and Surrounding Tissues to the Acute Inflammatory Challenge

# publications[].label
FLOW MODULATES CORONARY VENULAR PERMEABILITY BY A NITRIC OXIDE-RELATED MECHANISM

# publications[].label
Measurement of relative protein concentrations in rat mesentery lymphatics by UV absorbance photometry

# publications[].label
Prolonged intake of desloratadine: mesenteric lymphatic vessel dysfunction and development of obesity/metabolic syndrome.

# publications[].label
Chapter 4 Hydrodynamic regulation of lymphatic vessel transport function and the impact of aging

# publications[].label
Methods for lymphatic vessel culture and gene transfection.

# publications[].label
Mo1431  Inflammatory Bowel Disease (IBD) Induces Biliary Damage and Liver Fibrosis in an IBD Rat Model

# publications[].label
(PRO)RENIN AND ITS RECEPTOR DURING PREGNANCY AND PREECLAMSIA: A TRANSLATIONAL APPROACH WITH PATIENTS, A RAT MODEL AND IN VITRO STUDIES

# publications[].label
The effect of salt availability on salt intake in Dahl rats

# publications[].label
Regional variations of contractile activity in isolated rat lymphatics.

# publications[].label
Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation.

# publications[].label
TUBE FORMATION BY CORONARY VENULAR ENDOTHELIAL-CELLS SEEDED ON MATRIGEL IS MEDIATED BY AN FGF RECEPTOR PHOSPHOLIPASE-C PROTEIN-KINASE SIGNALING CASCADE

# publications[].label
Tu1737 IL-1 Inhibits Contraction of Intestinal Lymphatic Smooth Muscle -Implications for Chronic Gut Inflammation

# publications[].label
Alterations in Nitric Oxide-Mediated Signals in Coronary Arteries Following Spaceflight

# publications[].label
Abstract P423: INCREASED LEVELS OF URINARY ANGIOGENIC FACTORS AND MARINOBUFAGENIN IN PREECLAMPSIA PATEINT

# researcherOn[].label
Mast cell/histamine-mediated inflammation and subsequent decrease of lymphatic amyloid beta clearance accelerate progression of Alzheimer's disease

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Mast cell/histamine-mediated inflammation and subsequent decrease of lymphatic amyloid beta clearance accelerate progression of Alzheimer's disease

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Fluid Shift Associated Lymphostasis of the Gut Induces Inflammation and Microbial Intolerance (Postdoctoral Fellowship)

# researcherOn[].awardedBy.label
National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Lymphatic Fluid Flow Modeling with Active Network Components

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Heart, Lung, and Blood Institute

# researcherOn[].label
Role of renal lymphatics in blood pressure regulation

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Effects of Microgravity on Cerebral Arterial, Venous, and Lymphatic Function: Implications for Elevated Intracranial Pressure--NNX16AC28G

# researcherOn[].awardedBy.label
National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Markers of Vascular Risks Associated with Spaceflight Associated Neuro-ocular Syndrome

# researcherOn[].awardedBy.label
National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Effects of microgravity on lymphatic structure and function

# researcherOn[].awardedBy.label
National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Mast cell/histamine-mediated inflammation and subsequent decrease of lymphatic amyloid beta clearance accelerate progression of Alzheimer's disease

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].label
Role of mesenteric lymphatics and dietary endotoxin in metabolic syndrome

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Diabetes and Digestive and Kidney Disorders

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Heart, Lung, and Blood Institute

# researcherOn[].label
Effects of Microgravity on Ocular Vascular Hydrodynamics

# researcherOn[].awardedBy.label
National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States)

# researcherOn[].label
Transport Phenomena in the Lymphatic System

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Heart, Lung, and Blood Institute

# researcherOn[].label
Temporal impact of simulated microgravity on ocular vascular hydrodynamics

# researcherOn[].awardedBy.label
Ames Research Center - (Mountain View, California, United States)

# streetAddress
Medical Research & Education Building 2, Rm 1341; 8447 Riverside Parkway; 

# organizations[]
Texas A&M University Naresh K. Vashisht College of Medicine

# schools[]
Texas A&M University Naresh K. Vashisht College of Medicine