# keywords[]
Atp Binding Cassette Transporter, Subfamily B, Member 2

# keywords[]
Stem Cell Research - Nonembryonic - Human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
4009 Electronics, Sensors And Digital Hardware

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
Nadh, Nicotinamide Adenine Dinucleotide Reduced

# keywords[]
Kras, Kirsten Rat Sarcoma Viral Oncogene Homolog

# keywords[]
4.1 Discovery And Preclinical Testing Of Markers And Technologies

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
Machine Learning And Artificial Intelligence

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
4009 Electronics, Sensors And Digital Hardware

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
4009 Electronics, Sensors And Digital Hardware

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
Machine Learning And Artificial Intelligence

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Networking And Information Technology R&d (nitrd)

# keywords[]
Machine Learning And Artificial Intelligence

# keywords[]
Stem Cell Research - Nonembryonic - Non-human

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Cell Culture Techniques, Three Dimensional

# keywords[]
4009 Electronics, Sensors And Digital Hardware

# keywords[]
5102 Atomic, Molecular And Optical Physics

# keywords[]
30 Agricultural, Veterinary And Food Sciences

# keywords[]
Receptor, Transforming Growth Factor-beta Type Ii

# keywords[]
Receptors, Transforming Growth Factor Beta

# keywords[]
3214 Pharmacology And Pharmaceutical Sciences

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
Probability Theory, Stochastic Processes, And Statistics

# keywords[]
4.2 Evaluation Of Markers And Technologies

# keywords[]
1.1 Normal Biological Development And Functioning

# keywords[]
Squamous Cell Carcinoma Of Head And Neck

# keywords[]
Squamous Cell Carcinoma Of Head And Neck

# educationAndTraining[].organization.label
Vanderbilt University - (Nashville, Tennessee, United States)

# educationAndTraining[].organization.label
Vanderbilt University - (Nashville, Tennessee, United States)

# educationAndTraining[].organization.label
Vanderbilt University - (Nashville, Tennessee, United States)

# publications[].label
Fast autofluorescence imaging to evaluate dynamic changes in cell metabolism.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Carbomer-based adjuvant elicits CD8 T-cell immunity by inducing a distinct metabolic state in cross-presenting dendritic cells.

# publications[].label
Systems and methods for classifying activated T cells

# publications[].label
Polarization light-sheet microscopy and tomography (PLTo) for flow-based imaging of 3D microcarrier mesenchymal stem cell culture

# publications[].label
Evaluation of Cellpose segmentation with sequential thresholding for instance segmentation of cytoplasms within autofluorescence images.

# publications[].label
Quantitative analysis of label-free fluorescence lifetime images for single cell measurements of metabolism (Conference Presentation)

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
High-throughput measurements of the optical redox ratio using a commercial microplate reader.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Abstract P3-06-38: Optical metabolic imaging predicts therapeutic response in breast cancer tumors and organoids

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen.

# publications[].label
Single-cell analysis of autofluorescence lifetime images

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Differentiating quiescent cancer cell populations in heterogeneous samples with fluorescence lifetime imaging

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Decellularized organ biomatrices facilitate quantifiable in vitro 3D cancer metastasis models.

# publications[].label
In vivo fluorescence lifetime imaging captures metabolic changes in macrophages during wound responses in zebrafish

# publications[].label
Fluorescence lifetime imaging microscopy for metabolic analysis of LDHB inhibition in triple negative breast cancer.

# publications[].label
Propofol Treatment Alters the Metabolic State of MDA-MB-231 Breast Cancer Cells

# publications[].label
Optical metabolic imaging of live tissue cultures

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Design and Implementation of Privilege for Sale, a JEDI Activity for a Biomedical Engineering Introductory Course

# publications[].label
An automated image processing routine for segmentation of cell cytoplasms in high-resolution autofluorescence images

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Fluorescence intensity and lifetime redox ratios detect metabolic perturbations in T cells.

# publications[].label
Variation of fluorescence in tissue with temperature.

# publications[].label
Modeling key metabolic pathways of cancer cells using label-free fluorescence lifetime imaging

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Identification of rare cell populations in autofluorescence lifetime image data.

# publications[].label
Mutant KRAS Exosomes Alter the Metabolic StateofRecipient ColonicEpithelial Cells.

# publications[].label
Effects of pH on FAD autofluorescence lifetimes

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Perfusable Human Mesenchymal Stem Cell Patch Ameliorates Innate Immune Response

# publications[].label
A Novel Optical Metabolic Assay of Cancer Drug Efficacy in Primary 3D Tumor Cultures

# publications[].label
Identifying cancer cell metabolic states in autofluorescence lifetime images with machine learning

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Comparison of phasor analysis and biexponential decay curve fitting of autofluorescence lifetime imaging data for machine learning prediction of cellular phenotypes.

# publications[].label
Fluorescence Lifetime Imaging of Calcium Flux in Neurons in Response to Pulsed Infrared Light

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data.

# publications[].label
Short Infrared Laser Pulses Increase Cell Membrane Fluidity

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Systems and methods for sorting T cells by activation state

# publications[].label
Infrared light effects on coenzyme binding and cellular metabolism

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Seeing deep to map cell-biomaterial interactions via whole mount light sheet imaging and automated analytics in decellularized extracellular matrix models.

# publications[].label
In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment.

# publications[].label
Deconvolution of fluorescence lifetime imaging microscopy by a library of exponentials.

# publications[].label
Density-based clustering analyses to identify heterogeneous cellular sub-populations

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Classification of T-cell activation via autofluorescence lifetime imaging.

# publications[].label
Blind deconvolution estimation of fluorescence measurements through quadratic programming.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Effects of temperature on fluorescence in human tissue

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Optical imaging of zebrafish xenograft tumors for a high throughput drugs screen

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Label-free Detection and Characterization of Metabolism in Fresh and Cryopreserved Macrophages.

# publications[].label
Classifying T cell activity in autofluorescence intensity images with convolutional neural networks

# publications[].label
Comparison of polystyrene and hydrogel microcarriers for optical imaging of adherent cells.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Development of spectral markers for the discrimination of ulcerative colitis and Crohn's disease using Raman spectroscopy.

# publications[].label
Abstract 384: NADH oxidase, Enox1 activity, is required for vasculogenesis in Zebrafish.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
The effect of temperature on the autofluorescence of scattering and non-scattering tissue.

# publications[].label
Timelapse and volumetric imaging of mitochondrial networking using NAD(P)H autofluorescence via 2-photon microscopy

# publications[].label
Extracellular pH affects the fluorescence lifetimes of metabolic co-factors.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Osr1 Regulates Macrophage-mediated Liver Inflammation in Nonalcoholic Fatty Liver Disease Progression.

# publications[].label
Temporal and spatial binning of TCSPC data to improve signal-to-noise ratio and imaging speed

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response.

# publications[].label
The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Drug response in organoids generated from frozen primary tumor tissues.

# publications[].label
Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level.

# publications[].label
In vivo hyperspectral imaging of microvessel response to trastuzumab treatment in breast cancer xenografts.

# publications[].label
Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Zebrafish xenograft breast cancer models for high-throughput drug response screening

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Machine learning prediction of cancer cell metabolism from autofluorescence lifetime images

# publications[].label
Autofluorescence Imaging Resolves Early Cancer Treatment Response In Vivo

# publications[].label
Autofluorescence Imaging to Evaluate Cellular Metabolism

# publications[].label
Label-free spatially maintained measurements of metabolic phenotypes in cells.

# publications[].label
The effects of varying glucose concentrations on cellular glycolytic rates

# publications[].label
Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
150 Mutant KRAS-Dependent Changes in Exosomes and Recipient Cell Metabolism

# publications[].label
Autofluorescence is a biomarker of neural stem cell activation state

# publications[].label
Simulation and Analysis of Fluorescence Lifetime Image (FLIM) Data to Identify Rare Cells

# publications[].label
Fluorescence lifetime imaging of metabolic co-enzymes to determine cell type and function

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Widefield frequency-domain autofluorescence lifetime imaging for detecting breast cancer in murine xenograft tumor tissues.

# publications[].label
Label-free classification of T cell activation (Conference Presentation)

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth.

# publications[].label
The effect of temperature of fluorescence: an animal study

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
The novel antiangiogenic VJ115 inhibits the NADH oxidase ENOX1 and cytoskeleton-remodeling proteins.

# publications[].label
Optical imaging of metabolism in HER2 overexpressing breast cancer cells.

# publications[].label
Characterization of a multispectral visible imaging system for monitoring perfusion changes in dogs under anesthesia

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Comparison of polystyrene and hydrogel microcarriers for optical imaging of adherent cells

# publications[].label
Label-free optical imaging of cell function and collagen structure for cell-based therapies.

# publications[].label
Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

# publications[].label
Author Correction: Drug response in organoids generated from frozen primary tumor tissues.

# publications[].label
Abstract P5-01-01: Personalized neoadjuvant treatment planning using optical metabolic imaging

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
POSEA: A novel algorithm to evaluate the performance of multi-object instance image segmentation.

# publications[].label
Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype.

# publications[].label
Quantitative Autofluorescence Imaging Measures Early Response to Head and Neck Cancer Treatment In Vivo

# publications[].label
Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating features of native capillary network.

# publications[].label
Short Infrared Laser Pulses Block Action Potentials in Neurons

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Metabolic perturbations of macrophages on engineered collagen scaffolds with label-free fluorescence lifetime imaging (Conference Presentation)

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Optical metabolic imaging quantifies heterogeneous cell populations.

# publications[].label
Optical metabolic imaging identifies metabolic shifts and mitochondria heterogeneity in POLG mutator macrophages.

# publications[].label
Quantitative optical imaging of vascular response in vivo in a model of peripheral arterial disease.

# publications[].label
Abstract 4241: Predicting clinical response in breast cancer using cellular-resolution optical metabolic imaging

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Autofluorescence Imaging is Sensitive to CD4+ T cell Subtypes and Microenvironment

# publications[].label
Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed.

# publications[].label
Fluorescence lifetime image analysis code and example data of NADH and FAD images

# publications[].label
In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish.

# publications[].label
Autofluorescence is a biomarker of neural stem cell activation state.

# publications[].label
Carbomer-based Nano-Emulsion Adjuvant Enhances Dendritic Cell Cross-presentation via Lipid Body Formation Independent of Glycolysis

# publications[].label
Fluorescence Lifetime Measurements of NAD(P)H in Live Cells and Tissue

# publications[].label
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state.

# publications[].label
Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Classifying T cell activity in autofluorescence intensity images with convolutional neural networks.

# publications[].label
All Optical Experimental Design for Neuron Excitation, Inhibition, and Action Potential Detection

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer.

# publications[].publisher
American Association for Cancer Research (AACR)

# publications[].label
Action potential block in neurons by infrared light.

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma.

# publications[].label
Autofluorescence Imaging to Evaluate Cellular Metabolism.

# publications[].label
Label-free Method for Classification of T cell Activation

# publications[].label
Autofluorescence Imaging of T cell Activation

# publications[].label
Imaging Cellular Metabolic Heterogeneity in Cancer