# overview
Our long-term interest has been to understand the mechanisms of virus disease, specifically in potyviruses and potexviruses -- common families infecting a wide range of crops. We endeavor to use our understanding in engineering novel methods for crop disease control.

We have focused over the last decade on how virus proteins interact with cellular membranes in their host plants. We have uncovered genetic stress response machinery that appears to down-regulate virus infection, creating a tolerant state in the plant. When this stress response is compromised, the host plant becomes sick and necrotic. Our research aims to identify ways to increase plant vigor and yields in the face of virus infection, by empowering this cellular stress response machinery.

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European Mountain Ash Ringspot-associated Virus

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2.2 Factors Relating To The Physical Environment

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30 Agricultural, Veterinary And Food Sciences

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4.1 Discovery And Preclinical Testing Of Markers And Technologies

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30 Agricultural, Veterinary And Food Sciences

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4.1 Discovery And Preclinical Testing Of Markers And Technologies

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30 Agricultural, Veterinary And Food Sciences

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30 Agricultural, Veterinary And Food Sciences

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Reverse Transcriptase Polymerase Chain Reaction

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Bacilliform Dna Containing Plant Viruses

# educationAndTraining[].organization.label
Texas A&M University - (College Station, Texas, United States)

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Rutgers University - (New Brunswick, New Jersey, United States)

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Threat to control Canna Yellow Streak Virus; altered infectivity by associating with a Sub-viral element of novel Canna Yellow Mottle Virus

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Evidence for novel viruses by analysis of nucleic acids in virus-like particle fractions from Ambrosia psilostachya.

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Response of Hard Red Winter Wheat to Soilborne wheat mosaic virus Using Novel Inoculation Methods.

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Exploring the Host Range of Rose rosette Virus among Herbaceous Annual Plants.

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Multiple ER-to-nucleus stress signaling pathways are activated during Plantago asiatica mosaic virus and Turnip mosaic virus infection in Arabidopsis thaliana.

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Development of a Reverse Genetic System for Studying Rose Rosette Virus in Whole Plants.

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Comparative analysis of protein transport in the N. benthamiana vasculature reveals different destinations.

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When supply does not meet demand-ER stress and plant programmed cell death.

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Evidence that the potyvirus P1 proteinase functions in trans as an accessory factor for genome amplification.

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Subcellular targeting and interactions among the Potato virus X TGB proteins.

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Complete genome sequence of nine isolates of canna yellow streak virus reveals its relationship to the sugarcane mosaic virus (SCMV) subgroup of potyviruses.

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Complete genome sequences of nine isolates of Canna yellow streak virus reveal its relationship to Sugarcane mosaic virus subgroup of potyviruses, intraspecies genetic diversity and expands the natural host range of SCMV subgroup of potyviruses

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Potato virus X TGBp1 induces plasmodesmata gating and moves between cells in several host species whereas CP moves only in N. benthamiana leaves.

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Introduction to Special Issue of Molecular Plant Pathology - "Extracellular and intracellular perception of plant viruses".

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Cellular chaperones and folding enzymes are vital contributors to membrane bound replication and movement complexes during plant RNA virus infection.

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Cell-to-cell Movement of Potato Virus X Proteins in Different Plant Species

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Genetic diversity and molecular evolution of sugarcane mosaic virus, comparing whole genome and coat protein sequence phylogenies.

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Plant Virus Infection and the Ubiquitin Proteasome Machinery: Arms Race along the Endoplasmic Reticulum.

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Cell-to-cell movement of the 25K protein of potato virus X is regulated by three other viral proteins.

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Efficient silencing gene construct for resistance to multiple common bean (Phaseolus vulgaris L.) viruses.

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Genome-wide identification and characterization of Solanum tuberosum BiP genes reveal the role of the promoter architecture in BiP gene diversity.

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Soilborne wheat mosaic virus (SBWMV) 19K protein belongs to a class of cysteine rich proteins that suppress RNA silencing.

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Comprehensive Transcriptome Analysis Reveals Genome-Wide Changes Associated with Endoplasmic Reticulum (ER) Stress in Potato (Solanum tuberosum L.).

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A new cell-to-cell transport model for Potexviruses.

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Viruses Affecting Tropical and Subtropical Crops: Biology, Diversity, Management

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Magnetic virus-like nanoparticles in N. benthamiana plants: a new paradigm for environmental and agronomic biotechnological research.

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Potential of Greater Castanea Production in the United States

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Transcriptional Regulatory Networks Associate with Early Stages of Potato Virus X Infection of Solanum tuberosum.

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Debilitation of plant potyvirus infectivity by P1 proteinase-inactivating mutations and restoration by second-site modifications.

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Mutations in the region encoding the central domain of helper component-proteinase (HC-Pro) eliminate potato virus X/potyviral synergism.

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Phloem unloading of potato virus X movement proteins is regulated by virus and host factors.

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Reliable Detection for Bean yellow mosaic virus, Canna yellow streak virus, and Canna yellow mottle virus in Canna Varieties with Red Foliage.

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Beet necrotic yellow vein virus accumulates inside resting spores and zoosporangia of its vector Polymyxa betae BNYVV infects P. betae.

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The potato virus X TGBp2 protein association with the endoplasmic reticulum plays a role in but is not sufficient for viral cell-to-cell movement.

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SGT1 is induced by the potato virus X TGBp3 and enhances virus accumulation in Nicotiana benthamiana.

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Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts.

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The potato virus X TGBp2 movement protein associates with endoplasmic reticulum-derived vesicles during virus infection.

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Molecular characterization of two badnavirus genomes associated with Canna yellow mottle disease.

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Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes.

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Cell-to-cell movement of the PVX 12K, 8K, or coat proteins may depend on the host, leaf developmental stage, and the PVX 25K protein.

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Reliable detection for bean yellow mosaic virus, Canna yellow streak virus, And canna yellow mottle virus in canna varieties with red foliage

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UPR signaling at the nexus of plant viral, bacterial, and fungal defenses.

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Varied movement strategies employed by triple gene block-encoding viruses.

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Potyvirus And Potexviruses Small Membrane Binding Proteins Regulate bZIP60, bZIP28 and bZIP17 and Programmed Cell Death.

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The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast.

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Long-distance movement factor: a transport function of the potyvirus helper component proteinase.

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Mutations in the central domain of potato virus X TGBp2 eliminate granular vesicles and virus cell-to-cell trafficking.

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The complete genome sequence of Canna yellow streak virus isolated from Oklahoma grown canna

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Evidence that the 37 kDa protein of Soil-borne wheat mosaic virus is a virus movement protein

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Multiple ER-to-nucleus stress signaling pathways become active during Plantago asiatica mosaic virus and Turnip mosaic virus infection in Arabidopsis thaliana

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Concurrent suppression of virus replication and rescue of movement-defective virus in transgenic plants expressing the coat protein of potato virus X.

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How does the stressed out ER find relief during virus infection?

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Genetic modification of alternative respiration in Nicotiana benthamiana affects basal and salicylic acid-induced resistance to potato virus X.

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TGBp3 triggers the unfolded protein response and SKP1-dependent programmed cell death.

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Production of discernible disease phenotypes in Canna by five plant viruses belonging to the genera Potyvirus, Cucumovirus and Badnavirus

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New Insights into Hop Latent Viroid Detection, Infectivity, Host Range, and Transmission

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Genetic Diversity among Rose Rosette Virus Isolates: A Roadmap towards Studies of Gene Function and Pathogenicity.

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The unfolded protein response is triggered by a plant viral movement protein.

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The 35-kDa protein from the N-terminus of the potyviral polyprotein functions as a third virus-encoded proteinase.

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Mutational analysis of PVX TGBp3 links subcellular accumulation and protein turnover.

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Evidence that the 37 kDa protein of Soil-borne wheat mosaic virus is a virus movement protein.

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Role of unfolded protein response in plant virus infection.

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The ER quality control and ER associated degradation machineries are vital for viral pathogenesis.

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Analysis of potato virus X replicase and TGBp3 subcellular locations.

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Advancing the Rose Rosette Virus Minireplicon and Encapsidation System by Incorporating GFP, Mutations, and the CMV 2b Silencing Suppressor.

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Effects of aphids, barley yellow dwarf, and grassy weeds on grazed winter wheat

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A Reliable and Rapid Multiplex RT-PCR Assay for Detection of Two Potyviruses and a Pararetrovirus Infecting Canna Plants.

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bZIP60 and Bax inhibitor 1 contribute IRE1-dependent and independent roles to potexvirus infection.

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ER Stress and Viral Defense: Advances and Future Perspectives on Plant Unfolded Protein Response in Pathogenesis.

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The Potato virus X TGBp3 protein associates with the ER network for virus cell-to-cell movement.

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Mutational analysis of the tobacco etch potyviral 35-kDa proteinase: identification of essential residues and requirements for autoproteolysis.

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Potato virus X             : A global potato‐infecting virus and type member of the             Potexvirus             genus

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Cytoplasmic streaming enables the distribution of molecules and vesicles in large plant cells.

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Insight into the bZIP Gene Family in Solanum tuberosum: Genome and Transcriptome Analysis to Understand the Roles of Gene Diversification in Spatiotemporal Gene Expression and Function.

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How does the stressed out ER find relief during virus infection?

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Family Level Phylogenies Reveal Relationships of Plant Viruses within the Order Bunyavirales.

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Evidence that soilborne wheat mosaic virus moves long distance through the xylem in wheat.

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Introduction to Special Issue of Plant Virus Emergence.

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The IRE1/bZIP60 Pathway and Bax Inhibitor 1 Suppress Systemic Accumulation of Potyviruses and Potexviruses in Arabidopsis and Nicotiana benthamiana Plants.

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Soilborne wheat mosaic virus movement protein and RNA and wheat spindle streak mosaic virus coat protein accumulate inside resting spores of their vector, Polymyxa graminis.

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Soilborne viruses: advances in virus movement, virus induced gene silencing, and engineered resistance

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BIP and the unfolded protein response are important for potyvirus and potexvirus infection.

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Wrapping membranes around plant virus infection.

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Chapter 9 FORWARD Oklahoma State University Building an Academic Toolkit for Women at a Land-Grant Institution

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Analysis of protein transport in the Brassica oleracea vasculature reveals protein-specific destinations.

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Plasmodesmata transport of GFP alone or fused to potato virus X TGBp1 is diffusion driven.

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Molecular biology of potexviruses: recent advances.

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The plant endoplasmic reticulum UPRome: A repository and pathway browser for genes involved in signaling networks linked to the endoplasmic reticulum.

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In vivo translation of the triple gene block of potato virus X requires two subgenomic mRNAs.

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Investigating how the cellular ER stress machinery regulates plant virus infection

# researcherOn[].awardedBy.label
National Science Foundation - (Arlington, Virginia, United States)

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Improving virus resistance in Texas potato

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National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States)

# streetAddress
498 Olsen Blvd; Institute Plant Genomics and Biotech; 498 Olsen Blvd, Institute Plant Genomics and Biotech, Texas A&M University