# overview
Dr Svoboda is a well-established senior principal investigator with a broad background in developmental biology and cellular biology. Her research focus is on the cell biology of whole embryonic tissues, including cornea, cartilage, palate. Her lab has been funded from NIH, March of Dimes, Foundations and Private Companies for 3 decades. As a postdoctoral fellow at Harvard Medical School, she carried out cell and molecular biology experiments on developing systems and worked with Dr. Elizabeth Hay when she developed her theories on cell-matrix interactions. As PI or co-Investigator on many previous university- and March of Dimes funded grants (over 30 years of continuous funding), she worked on how cell-matrix interactions change during development. In addition, she was a mentor on two training grants (T32 and KL2) and has successfully administered other NIH supported developmental and cell biology projects (e.g. staffing, research protections, and budget), collaborated with other researchers, and produced peer-reviewed publications from each project.

She has a new project that contributes evidence to the theory that periocular mesenchyme (POM) cells contribute to the development of the ciliary body, trabecular meshwork and the iridocorneal angle. The objective of this project is to determine if Gli1 positive cells contribute to the POM and anterior eye structures by using inducible Gli1-CreERT2; tdTomatoflox (Gli1-tdTomato) mouse model. Experiments were recently completed that demonstrated the Gli1 + cells were also positive for Pitx2, FOXC1, and FOXC2, known markers for periocular mesenchyme during anterior eye development.

She has successfully trained 40 Postdoctoral, Ph.D., M.S. graduate students, undergraduate, medical and dental predoctoral students, and college/high school summer research trainees.

# keywords[]
1.1 Normal Biological Development And Functioning

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3205 Medical Biochemistry And Metabolomics

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1.1 Normal Biological Development And Functioning

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Physical Injury - Accidents And Adverse Effects

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1.1 Normal Biological Development And Functioning

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Physical Injury - Accidents And Adverse Effects

# keywords[]
1.1 Normal Biological Development And Functioning

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1.1 Normal Biological Development And Functioning

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3205 Medical Biochemistry And Metabolomics

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Reverse Transcriptase Polymerase Chain Reaction

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1.1 Normal Biological Development And Functioning

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1.1 Normal Biological Development And Functioning

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1.1 Normal Biological Development And Functioning

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3214 Pharmacology And Pharmaceutical Sciences

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Physical Injury - Accidents And Adverse Effects

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Physical Injury - Accidents And Adverse Effects

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Reverse Transcriptase Polymerase Chain Reaction

# keywords[]
Physical Injury - Accidents And Adverse Effects

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4009 Electronics, Sensors And Digital Hardware

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5102 Atomic, Molecular And Optical Physics

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3205 Medical Biochemistry And Metabolomics

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Reverse Transcriptase Polymerase Chain Reaction

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Receptor Activator Of Nuclear Factor-kappa B

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1.1 Normal Biological Development And Functioning

# educationAndTraining[].organization.label
University of Nebraska Medical Center - (Omaha, Nebraska, United States)

# educationAndTraining[].organization.label
University of Nebraska Medical Center - (Omaha, Nebraska, United States)

# educationAndTraining[].organization.label
University of Nebraska at Omaha - (Omaha, Nebraska, United States)

# awardsAndHonors[].label
UNMC Graduate Studies Council Distinguished Alumnus Award

# awardsAndHonors[].label
Anatomical Record Service Award as the Publications Committee Chair and Advocate

# publications[].label
Collagen XXIV Null Mouse Bones Are Not Osteoporotic Due to an Insufficiency of Osteoblastogenesis Factors

# publications[].label
Instrumentation Grant Savvy - What's the Best Fit for Your Institution?

# publications[].label
An analysis of cell shape and the neuroepithelial basal lamina during optic vesicle formation in the mouse embryo.

# publications[].label
The NH2-terminal and COOH-terminal fragments of dentin matrix protein 1 (DMP1) localize differently in the compartments of dentin and growth plate of bone.

# publications[].label
Antioxidants Modulate Oral Fibroblasts Response to Reactive Oxygen Species Inducing Agents

# publications[].label
Characterization of a trinitrobenzene sulphonic acid (TNBS)-induced mouse model of Periodontitis

# publications[].label
Embryonic corneal mesenchymal cells required Rho for EGF stimulation.

# publications[].label
High-throughput assays for gingival fibroblast in vitro wounds treated with nicotine, and/or TGF1

# publications[].label
INTEGRIN SUBUNIT ANTIBODIES (BETA-1, ALPHA-2 AND ALPHA-3) INHIBIT TYPE-X COLLAGEN SECRETION AND INCREASE METALLOPROTEINASE INHIBITOR EXPRESSION IN SERUM-FREE CARTILAGE ORGAN

# publications[].label
Nicotine modulates nicotinic receptors and PI-3 kinase pathway in medial edge epithelia (MEE) during palate fusion

# publications[].label
ECM stimulated actin reorganization in corneal epithelia can be modulated by disruption of the Rho signaling pathway

# publications[].label
Cellular invasion and collagen type IX in the primary corneal stroma in vitro.

# publications[].label
Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells.

# publications[].label
ECM-stimulated actin bundle formation in embryonic corneal epithelia is tyrosine phosphorylation dependent

# publications[].label
Characterization of the sternal chondrocyte cell matrix attachment complex in situ.

# publications[].label
ECM-stimulated actin bundle formation in embryonic corneal epithelia is tyrosine phosphorylation dependent.

# publications[].label
Detecting early apoptosis in whole epithelial sheets with PhiPhiLux and confocal microscopy

# publications[].label
Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016.

# publications[].label
The twist protein is upregulated in MEE prior to EMT during palatal fusion

# publications[].label
Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells.

# publications[].label
Effect of ADAM17 on EMMPRIN Expression after Vesicant Injury to the Cornea

# publications[].label
AMMONIA PRODUCTION AGGREGATE WITH 1360 TONES PER DAY OUTPUT VAPOR REFORMING PRODUCTION UNIT INSPECTION

# publications[].label
Detecting Early Apoptosis in Whole Epithelial Sheets with a Caspase 3 Substrate, Phiphilux and Annexes V Using Confocal Microscopy

# publications[].label
Cell-Cell and -Matrix Interactions on Nanofibrous Scaffolds

# publications[].label
Histology of NeoMTA Plus and Quick-Set2 in Contact with Pulp and Periradicular Tissues in a Canine Model.

# publications[].label
Increased cell diameter precedes chondrocyte terminal differentiation, whereas cell-matrix attachment complex proteins appear constant

# publications[].label
Ephrin reverse signaling mediates palatal fusion and epithelial-to-mesenchymal transition independently of Tgf3.

# publications[].label
Antioxidant combinations protect oral fibroblasts against metal-induced toxicity.

# publications[].label
Efficacy of 38% silver diamine fluoride in reducing gingival inflammation and plaque accumulation in older adults living in retirement-homes: A randomized controlled pilot trial.

# publications[].label
Intracellular changes may precede specific hypertrophic markers in differentiating chondrocytes

# publications[].label
Vacuum-induced suction stimulates increased numbers of blood vessels in healthy dog gingiva

# publications[].label
FLUORESCENT INSITU HYBRIDIZATION FOR ACTIN MESSAGE IN THE CHICK COCHLEA ANALYZED WITH CONFOCAL MICROSCOPY

# publications[].label
Nicotine inhibits myofibroblasts differentiation in human gingival fibroblasts

# publications[].label
FOCAL ADHESION KINASE (FAK) AND OTHER PROTEINS ARE PHOSPHORYLATED IN CORNEAL EPITHELIA IN THE PRESENCE OF ECM

# publications[].label
Consequences of the loss of collagen XXIV in bone

# publications[].label
IN VITRO CAPILLARY ENDOTHELIAL TUBES AS A MODEL SYSTEM TO STUDY CYTOTOXICITY OF DIESEL PARTICLES

# publications[].label
Establishment of a whole-chick sternum model that recapitulates normal cartilage development.

# publications[].label
Nicotine inhibits human gingival fibroblast migration via modulation of Rac signalling pathways.

# publications[].label
Mustard injured skin: are matricellular proteins involved in the delay of wound repair?

# publications[].label
Reactive oxygen species and antioxidant defense mechanisms in the oral cavity: a literature review.

# publications[].label
TYPE-IX COLLAGEN DISTRIBUTION AND EXPRESSION IN THE EMBRYONIC AVIAN CORNEA

# publications[].label
ACTIN CYTOSKELETAL INVOLVEMENT IN EXTRACELLULAR-MATRIX (ECM) STIMULATION OF EPITHELIAL COLLAGEN PRODUCTION

# publications[].label
SM1997 downregulates mustard-induced enzymes that disrupt corneal epithelial attachment.

# publications[].label
Macrophage morphology and migration are influenced by ECM substrate

# publications[].label
30 years in 30 minutes: integrating imaging, cell and developmental biology with teaching and service

# publications[].label
TGF-3 induced EMT of the chicken palatal shelves is PI-3 kinase dependent

# publications[].label
Doxycycline, AminoPlex and a Retro Olvanil Hydroxamate Reduce pEGFR Levels after Mustard Exposure and Improve Corneal Wound Healing

# publications[].label
INTRACELLULAR LABELING OF BETA-ACTIN MESSENGER-RNA USING REVERSE-TRANSCRIPTASE INCORPORATED BIOTIN-DUTP INTO THE ACTIN CORTICAL MAT OF CORNEAL EPITHELIAL-CELLS

# publications[].label
Reactive oxygen species and antioxidant defense mechanisms in the oral cavity: a literature review.

# publications[].label
Evaluation of an automated dental unit water system's contamination control protocol.

# publications[].label
Erratum: Establishment of a whole-chick sternum model that recapitulates normal cartilage development (Biotechniques (April 1998) 24 (632-636))

# publications[].label
Growth Factors and Signaling Proteins in Craniofacial Development

# publications[].label
Activation of RANKL and MMP Production by Endothelin Signaling in Cultured Periodontal Fibroblasts

# publications[].label
N-terminal and C-terminal fragments of dentin matrix protein 1(DMP1) are distributed differently in bone, dentin and cells.

# publications[].label
Extracellular matrix protein expression in terminally differentiating chondrocytes is integrin mediated.

# publications[].label
Embryonic corneal epithelial interaction with exogenous laminin and basal lamina is F-actin dependent.

# publications[].label
Cell-cell and cell-matrix Interactions on Biomimetic 3D Scaffolds

# publications[].label
Upregulation of gamma-2 laminin-332 in the mouse ear vesicant wound model.

# publications[].label
Approaches to studying cellular signaling: a primer for morphologists.

# publications[].label
Quantitation of collagen and fibronectin binding to whole sheets of epithelia with confocal microscopy

# publications[].label
ABERRANT EXPRESSION OF KERATINS IN CORNEA AND SKIN OF BSK MICE

# publications[].label
Expression of Eph Receptors and their Ligands in Palate

# publications[].label
Zyxin and vinculin distribution at the cell-extracellular matrix attachment complex (CMAX) in corneal epithelial tissue are actin dependent.

# publications[].label
Distribution of F-actin, vinculin and integrin subunits (alpha 6 and beta 4) in response to corneal substrata.

# publications[].label
ACTIN MESSENGER-RNA HAS A POLARIZED DISTRIBUTION IN EMBRYONIC CORNEAL EPITHELIA

# publications[].label
Electroporation and transfection of GFP-actin plasmids into whole embryonic corneal epithelia

# publications[].label
Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts.

# publications[].label
Comparison and modulation of the Rho mediated signaling pathways in dermal and embryonic corneal fibroblasts.

# publications[].label
Primary osteoblasts colonize and mineralize 3D nanofibrous gelatin scaffolds in 14 days

# publications[].label
Integration of Active-Learning Activity Increased Short-Term and Long-Term Retention in a Self-Learning Setting

# publications[].label
Intracellular localization of types I and II collagen mRNA and endoplasmic reticulum in embryonic corneal epithelia.

# publications[].label
HEALING OF CORNEAL WOUNDS INDUCED BY VESICANTS

# publications[].label
Disrupting integrin mediated signal transduction pathways increases annexin V binding and caspase 3 activity in embryonic corneal epithelia

# publications[].label
The role of twist during palate development.

# publications[].label
Inhibition of twist expression blocks palatal fusion

# publications[].label
Expression of metalloproteinases and their inhibitors change when sternal cartilage is organ cultured with integrin antibodies.

# publications[].label
LOW-DOSES OF CYTOCHALASIN-D DO NOT AGGREGATE F-ACTIN AND DO STIMULATE COLLAGEN PRODUCTION IN EMBRYONIC AVIAN CORNEAL EPITHELIA

# publications[].label
Rho mediated signaling pathways in embryonic corneal fibroblasts and epithelia

# publications[].label
Dental Pulp Stem Cell Polarization: Effects of Biophysical Factors.

# publications[].label
Extracellular matrix: The proteins that function throughout the body.

# publications[].label
Treatment of gum diseases and gum disorders with TSG-6 protein

# publications[].label
Cleft lip and palate genetics and application in early embryological development

# publications[].label
ACTIN CYTOSKELETON ORGANIZATION IS SUBSTRATE-DEPENDENT IN WHOLE CORNEAL EPITHELIAL TISSUE

# publications[].label
TGF Signaling Regulates Decorin and Biglycan Expression and Distribution During Murine Palatal Fusion

# publications[].label
Regulation of epithelial-mesenchymal transition in palatal fusion.

# publications[].label
MEDIA VARIATIONS IN WHOLE EMBRYO CULTURE

# publications[].label
Analysis of Snail1 function and regulation by Twist1 in palatal fusion.

# publications[].label
Bioactive polyphenol antioxidants protect oral fibroblasts from ROS-inducing agents.

# publications[].label
Inhibiting ADAM17 after Ocular Mustard Exposure Reduces EMMPRIN Expression as well as MMP-9 Activation

# publications[].label
THE INTRACELLULAR-DISTRIBUTION OF VINCULIN AND ALPHA(2)-INTEGRIN IN EPITHELIAL-CELLS AND CHONDROCYTES

# publications[].label
Rho is required for EGF stimulation in avian embryonic corneal fibroblasts

# publications[].label
ECM stimulated actin reorganization in corneal epithelia involves phosphorylation of actin associated proteins

# publications[].label
METHANE VAPOR CONVERSION TUBE FURMANCE CALCULATION MODEL EXPERIMENTAL CONTROL

# publications[].label
Gli1+ Periodontal Mesenchymal Stem Cells in Periodontitis.

# publications[].label
Hyperbaric oxygen downregulates ICAM-1 expression induced by hypoxia and hypoglycemia: the role of NOS.

# publications[].label
Second harmonic signal analysis demonstrates that avian (E17) corneal collagen fibrils and keratocytes rotate 200 degrees in the anterior stroma

# publications[].label
CYTOSKELETON AND GENE-EXPRESSION IN THE CORNEA

# publications[].label
Cell polarization: From epithelial cells to odontoblasts.

# publications[].label
Nicotine inhibits palatal fusion and modulates nicotinic receptors and the PI3 kinase pathway in medial edge epithelia*

# publications[].label
Connexin 43 Antisense Therapy Modulates Connexin Expression and Wound Repair in Nitrogen Mustard Injured Mouse Skin

# publications[].label
CONFOCAL MICROSCOPY OF WHOLE-MOUNT EMBRYONIC CARTILAGE - INTRACELLULAR-LOCALIZATION OF F-ACTIN, CHICK PROLYL HYDROXYLASE AND TYPE-II COLLAGEN MESSENGER-RNA

# publications[].label
Managing a small core facility and maintaining your sanity

# publications[].label
Optic vesicle defects induced by vincristine sulfate: an in vivo and in vitro study in the mouse embryo.

# publications[].label
Tracking Periocular Mesenchyme (POM) Development with Gli1CreERT2; tdTomatoflox Labeled Cells in Mice

# publications[].label
[Penetrating laryngotracheal injury during a suicide attempt].

# publications[].label
CHARACTERIZATION OF EMBRYONIC AVIAN EPIDERMIS

# publications[].label
Disrupting the Rho signaling pathway in embryonic corneal epithlelia blocks ECM stimulated actin reorganization.

# publications[].label
In memoriam: Mark Alan Nathanson, 19472006

# publications[].label
Parathyroid hormone/parathyroid hormone-related peptide modulates growth of avian sternal cartilage via chondrocytic proliferation

# publications[].label
Terminal chondrocyte differentiation and type X collagen production is inhibited by parathyroid hormone (PTH) in cultured whole chick sterna

# publications[].label
Beta 1 integrin antibodies inhibit chondrocyte terminal differentiation in whole sterna.

# publications[].label
Method of Studying Palatal Fusion using Static Organ Culture.

# publications[].label
Cell fate mediators Notch and Twist in mouse mandibular condylar cartilage.

# publications[].label
DISTRIBUTION OF CYTOSKELETAL PROTEINS IN EMBRYONIC AVIAN EPIDERMIS

# publications[].label
ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium.

# publications[].label
An in vivo comparison of wound healing characteristics of two commercial acellular dermal matrices.

# publications[].label
Hydroxamates Inhibit EMMPRIN as well as ADAM17/TACE and MMPs

# publications[].label
Nicotine regulates Akt phosphorylation in medial edge epithelia and inhibits palatal fusion

# publications[].label
Chondrocyte survival and differentiation in situ are integrin mediated

# publications[].label
Mouse Genotype Alters Palatal Fusion Response to Nicotine

# publications[].label
Comparative studies of biorad and leica confocal laser scanning microscopes

# publications[].label
Effect of parathyroid hormone on the release of reactive oxygen species in developing cartilage.

# publications[].label
Parathyroid hormone/parathyroid hormone-related peptide modulates growth of avian sternal cartilage via chondrocytic proliferation.

# publications[].label
ECM stimulated reorganization of the actin cortical mat in epithelial tissues may involve tensin, paxillin and focal adhesion kinase

# publications[].label
Erk and PI-3 kinase are necessary for collagen binding and actin reorganization in corneal epithelia.

# publications[].label
Comparing dentinal tubule penetration of conventional and 'HiFlow' bioceramic sealers with resin-based sealer: An in vitro study.

# publications[].label
Periocular Mesenchyme (POM) Contributes to Anterior Eye Structures

# publications[].label
Transfection conditions for whole embryonic corneal epithelia

# publications[].label
Corneal epithelial actin reorganization and tyrosine phosphorylation are p160 ROCK kinase dependent.

# publications[].label
In vivo imaging of dendritic calcium dynamics

# publications[].label
Collagen expression and orientation in ocular tissues

# publications[].label
Type IV Collagenase Inhibitor, BiPS, Alters Matrix Metalloproteinase 9 Expression in Sulfur Mustard Exposed Mouse Skin

# publications[].label
Subject Specific Cross Word Puzzles Were Effective Active Learning Tools

# publications[].label
Ephrin reverse signaling induces mouse palatal fusion without TGF3 signaling (921.4)

# publications[].label
Gq pathway inhibition modulates PTH/PTHrP regulation of chondrogenic differentiation

# publications[].label
Increased cell diameter precedes chondrocyte terminal differentiation, whereas cell-matrix attachment complex proteins appear constant.

# publications[].label
The ''cell-matrix attachment complex'' (CMAX) in embryonic epithelia contains zyxin and vinculin.

# publications[].label
The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs.

# publications[].label
Comparison of Vibringe, EndoActivator, and needle irrigation on sealer penetration in extracted human teeth.

# publications[].label
Effects of hydrogen peroxide on dental unit biofilms and treatment water contamination.

# publications[].label
ELASTIC PROPERTIES OF EXTRACTED RED-BLOOD-CELL MEMBRANE SKELETONS

# publications[].label
Ephrin Reverse Signaling Induces Mouse Palatal Fusion and Epithelial To Mesenchymal Transition In Cultured Medial Edge Epithelia

# publications[].label
The effect of an antioxidant gel compared to chlorhexidine during the soft tissue healing process: An animal study.

# publications[].label
The Coalition of American Societies for Anatomy (CASA): Working together to improve opportunities

# publications[].label
The intracellular distribution of vinculin and alpha 2 integrin in epithelial cells and chondrocytes.

# publications[].label
Equivalent UVB-induced and NM-induced corneal injuries heal at different speeds over the course of 7 days post exposure

# publications[].label
SPARC and Hevin in Corneal Healing after Nitrogen Mustard and UVB Injury

# publications[].label
THE EFFECTS OF VINCRISTINE SULFATE ON MOUSE EMBRYO GROWTH, DEVELOPMENT, AND OPTIC VESICLE FORMATION

# publications[].label
Nicotinic receptors are expressed in medial edge epithelia during palate development and nicotine inhibits palate fusion in vitro

# publications[].label
Antioxidants Increased In Vitro Wound Healing of Nicotine-Treated Oral Fibroblasts

# publications[].label
Embryonic chick corneal epithelium: a model system for exploring cell-matrix interactions.

# publications[].label
Selected abstracts of the Seventeenth Annual Meeting of the East Coast Connective Tissue Society

# publications[].label
Map kinase signaling pathway are necessary for ACM reorganization in avian corneal epithelia.

# publications[].label
Sheets of embryonic epidermis can be isolated and cultured with or without the basal lamina.

# publications[].label
Vacuum-induced Suction Stimulates Increased Numbers of Blood Vessels in Healthy Dog Gingiva.

# publications[].label
Digital vs Paper Histology Lab Exams: Pros and Cons

# publications[].label
Effects of estrogen on chondrocyte proliferation and collagen synthesis in skeletally mature articular cartilage.

# publications[].label
Chapter 4 Cell-Matrix Interactions and Signal Transduction

# publications[].label
Cleft lip and palate genetics and application in early embryological development.

# publications[].label
Bioactive Antioxidants Regulate RAC-GTP Expression at the Leading Edge of Migrating Oral Fibroblasts

# publications[].label
Ephrin reverse signaling induces mouse palatal fusion without TGF3 signaling

# publications[].label
Rac signaling pathway is involved in fibroblast migration

# publications[].label
ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure.

# publications[].publisher
Association for Research in Vision and Ophthalmology (ARVO)

# publications[].label
Murine Genotype Alters Palatal Tissue Response to Nicotine

# publications[].label
THE NORMAL DEVELOPMENT OF THE MAMMALIAN OPTIC VESICLE

# publications[].label
Nicotine effects on wound healing in human gingival fibroblasts.

# publications[].label
Characterization of Bsk mice: I. The Bsk mutation does not involve a recombination of cornea-specific keratin 12 and skin-specific hair keratin genes.

# publications[].label
TGF beta Signaling Regulates Decorin and Biglycan Expression and Distribution During Murine Palatal Fusion

# publications[].label
CORNEAL EPITHELIAL INTERACTION WITH BASEMENT-MEMBRANE IS ACTIN DEPENDENT

# publications[].label
Rho is present and phosphorylated in avian corneal epithelia cultured in the presence of ECM molecules.

# publications[].label
The intracellular distribution and modulation of zyxin in response to actin disruption in whole embryonic corneal epithelia

# publications[].label
Inhibition of ECM-stimulated ACM reorganization in avian corneal epithelia using a specific MAP kinase inhibitor (PD98059)

# publications[].label
Type IV Collagenase Inhibitor, BiPS, Alters Matrix Metalloproteinase 9 Expression in Sulfur Mustard Exposed Mouse Skin

# publications[].label
Anti-inflammatory protein tumor necrosis factor--stimulated protein 6 (TSG-6) promotes early gingival wound healing: an in vivo study.

# publications[].label
Analyzing Smooth muscle actin and E-cadherin in fibroblasts/carcinoma cells co-culture system

# publications[].label
A Short Review on PEGASOS Tissue Clearing Method and Deep Imaging of Oral and Craniofacial Tissues

# publications[].label
Tensin, paxillin and focal adhesion kinase may be involved in actin reorganization stimulated by ECM in corneal epithelia

# publications[].label
Chondrocyte survival and differentiation in situ are integrin mediated

# publications[].label
MICROTUBULES IN OPTIC VESICLE DEVELOPMENT - AN INVIVO AND INVITRO STUDY

# publications[].label
ACTIN AND ALPHA-ACTININ DISTRIBUTION IN EMBRYONIC AVIAN CORNEAL EPITHELIA

# publications[].label
Cell-Matrix Interactions and Signal Transduction

# publications[].label
Diesel exhaust particle exposure causes redistribution of endothelial tube VE-cadherin.

# publications[].label
Map kinase and PI3 kinase are downstream of Rho and Fak in the integrin mediated signaling cascade necessary for ACM reorganization in avian corneal epithelia

# publications[].label
Antioxidants Counteract Metal-Induced Toxicity in Oral Fibroblasts

# publications[].label
Precursors of macrophages in embryonic rat lungs fail to exhibit granulocyte-forming potential.

# publications[].label
Chondrocyte terminal differentiation, apoptosis, and type X collagen expression are downregulated by parathyroid hormone.

# publications[].label
The molecules in the corneal basement membrane zone affected by mustard exposure suggest potential therapies.

# publications[].label
COLLAGEN-SYNTHESIS BY CORNEAL EPITHELIA WITH OR WITHOUT A BASAL LAMINA IN THE PRESENCE OF CYTOCHALASIN-D

# publications[].label
THE EFFECTS OF VINCRISTINE SULFATE ON OPTIC VESICLE FORMATION IN THE MOUSE EMBRYO

# publications[].label
Doxycycline hydrogels as a potential therapy for ocular vesicant injury.

# publications[].label
The biological function of type I receptors of bone morphogenetic protein in bone.

# publications[].label
Second Harmonic Signal Analysis of Whole Embryonic Avian Corneas

# publications[].label
Cell-matrix and cell-cell interactions of human gingival fibroblasts on three-dimensional nanofibrous gelatin scaffolds.

# publications[].label
ZYXIN AND VINCULIN ARE LOCALIZED IN CELL-MATRIX ATTACHMENT COMPLEXES (CMAX) IN EMBRYONIC CORNEAL EPITHELIA

# publications[].label
Fibronectin stimulated actin reorganization in corneal epithelial sheets is Rho but not Raf dependent.

# publications[].label
Analyzing epithelial-mesenchymal transition regulators in human oral cancer and precancerous lesions

# publications[].label
INTRACELLULAR-LOCALIZATION OF VINCULIN AND GELSOLIN IN EMBRYONIC AVIAN CORNEAL EPITHELIA

# publications[].label
Pharmacological targeting of the IL-6 signalling pathway in human melanoma cells of different stages

# publications[].label
Embryonic corneal epithelial actin alters distribution in response to laminin.

# publications[].label
Method of Studying Palatal Fusion using Static Organ Culture

# publications[].label
Nicotine inhibits myofibroblast differentiation in human gingival fibroblasts.

# publications[].label
Nitrogen mustard exposure of the cornea induces erk activation of adam17 within minutes

# publications[].label
Signal transduction pathways involved in epithelial-mesenchymal transition in oral cancer compared with other cancers.

# publications[].label
How may paths exist from the membrane to the nucleus?

# publications[].label
PI3 kinase and map kinase mediate actin reorganization and collagen binding in avian corneal epithelia.

# publications[].label
Spatial and Temporal Similarities between Laminin-332 and Keratin-5 during Wound Repair

# publications[].label
Parathyroid hormone (PTH) inhibits terminal chondrocyte differentiation and type X collagen production in cultured whole chick sterna.

# publications[].label
Nicotine inhibits myofibroblasts differentiation and down-regulates TGF-1-induced p38 MAPK activity in human gingival fibroblasts

# publications[].label
Chondrocyte survival and differentiation in situ are integrin mediated.

# publications[].label
PI-3 kinase activity is required for epithelial-mesenchymal transformation during palate fusion.

# publications[].label
Embryonic chicken cornea and cartilage synthesize type IX collagen molecules with different amino-terminal domains.

# publications[].publisher
Proceedings of the National Academy of Sciences

# publications[].label
ULTRASTRUCTURE OF NEURAL FOLD FUSION IN THE SACRAL REGION OF THE MOUSE EMBRYO

# publications[].label
Ephrin reverse signaling controls palate fusion via a PI3 kinase-dependent mechanism.

# publications[].label
FLUORESCENT INSITU HYBRIDIZATION (FISH) IN WHOLE MOUNT EMBRYONIC AVIAN CORNEA

# publications[].label
Tracking Periocular Mesenchyme (POM) Development with Gli1-CreERT2; tdTomatoflox Labeled Cells in Mice

# publications[].label
Effect of ADAM17 on EMMPRIN Expression after Vesicant Injury to the Cornea

# publications[].label
Ephrin reverse signaling controls palate fusion through a PI3 Kinase dependant mechanism

# publications[].label
Modulation of the Rho mediated signaling pathways in embryonic corneal fibroblasts

# publications[].label
Collagen, fibronectin and lysophosphatidic acid decreased caspase-3 activity while inhibiting ROCK (Y27632) increased caspase-3 activity in whole epithelial sheets

# publications[].label
CHARACTERIZATION OF EMBRYONIC AVIAN EPIDERMIS

# publications[].label
Student Survey Results on the Integration of Active Learning Exercises in a Dental Education Self-Learning Setting

# publications[].label
Intracellular distribution of type II collagen mRNA and prolyl 4-hydroxylase in embryonic avian corneal epithelia.

# publications[].label
A tribute to Elizabeth D. Hay, 1927-2007.

# publications[].label
LAMININ STIMULATED ACTIN CORTICAL MAT REORGANIZATION IS TYROSINE PHOSPHORYLATION-DEPENDENT IN EMBRYONIC AVIAN CORNEAL EPITHELIA

# publications[].label
ECM-stimulated signaling and actin reorganization in embryonic corneal epithelia are Rho dependent.

# publications[].label
Intracellular distribution of beta-actin mRNA is polarized in embryonic corneal epithelia.

# publications[].label
Extracellular Matrix in Secondary Palate Development.

# publications[].label
INTRACELLULAR-LOCALIZATION OF CHICK PROLYL HYDROXYLASE AND COLLAGEN MESSENGER-RNA IN EMBRYONIC AVIAN CORNEA

# publications[].label
Timed Induction of Gli1 (P3 To P30) Was Expressed In Mouse Trabecular Meshwork

# publications[].label
Biglycan and Decorin Expression and Distribution in Palatal Adhesion.

# publications[].label
CHONDROCYTES PROVIDE A MODEL FOR IN-SITU CONFOCAL MICROSCOPY AND 3D RECONSTRUCTIONS

# publications[].publisher
SPIE, the international society for optics and photonics

# publications[].label
Collagen Macrostructure and Corneal Shape: Lessons from Different Species

# publications[].label
Ephrin Reverse Signaling Mediates Palatal Fusion and Epithelial-to-Mesenchymal Transition Independently of Tgfss3.

# publications[].label
Bioactive Polyphenol Antioxidants Protect Oral Fibroblasts From ROS Inducing Agents

# publications[].label
Expression of Collagen Types I, II, IX, and X in the Mineralizing Turkey Gastrocnemius Tendon.

# publications[].label
Tracking Mesenchyme Primordial Cells with Gli1 Labeled the Optic Nerve Head and Periocular Mesenchyme

# publications[].label
Twist and E47 regulate Snail promoter activity in palatogenesis

# publications[].label
PTH stimulated growth and decreased Col-X deposition are phosphotidylinositol-3,4,5 triphosphate kinase and mitogen activating protein kinase dependent in avian sterna.

# publications[].label
Attenuating Ocular Sulfur Mustard Injury with Restasis

# publications[].label
Activation of Receptor Activator of Nuclear Factor-B Ligand and Matrix Metalloproteinase Production in Periodontal Fibroblasts by Endothelin Signaling.

# publications[].label
THE TERATOGENETIC EFFECTS OF VINCRISTINE SULFATE ON GROWTH, DEVELOPMENT, AND OPTIC VESICLE FORMATION IN THE EARLY SOMITE MOUSE EMBRYO

# publications[].label
ECM stimulated actin reorganization in corneal epithelia is PI3 kinase, MAP kinase, Rho and p160 ROCK dependent.

# publications[].label
Zyxin and vinculin distribution at the cell-extracellular matrix attachment complex (CMAX) in corneal epithelial tissue are actin dependent

# publications[].label
Consequences of the loss of collagen XXIV in bone (922.7)

# publications[].label
Cardiolipids dysregulate the human monocyte response to P-gingivalis LPS

# publications[].label
The rho signaling pathway is involved in embryonic corneal epithelia ECM stimulated actin reorganization

# publications[].label
Epithelial-mesenchymal transformation during palate fusion requires PI3 kinase activity

# publications[].label
Sulfur mustard induces an endoplasmic reticulum stress response in the mouse ear vesicant model.

# publications[].label
Signal transduction pathways interrupted by nicotine may lead to delayed wound healing

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Corneal Wound Healing is Facilitated by Hydroxamates that Reduce EMMPRIN Expression

# publications[].label
Intracellular relationship between actin and alpha-actinin in a whole corneal epithelial tissue.

# researcherOn[].label
Mechanism of Ephrin Signaling in Mammalian Palatal Fusion

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.preferredLabel
DHHS-NIH-National Institute of Dental and Craniofacial Research

# researcherOn[].label
R01DE032540 - Regulation of dental pulp stem cell polarization for tubular dentin regeneration

# researcherOn[].awardedBy.label
National Institutes of Health - (Bethesda, Maryland, United States)

# researcherOn[].awardedBy.label
National Institute of Dental and Craniofacial Research - (Bethesda, Maryland, United States)

# streetAddress
3302 Gaston Ave; Biomedical Sciences; 3302 Gaston Avenue