First name,Last name,Preferred title,Overview,Position,Department,Individual
Praveena,Kanchupati,Lecturer,,Lecturer,Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n40015256
Geoffrey,Kapler,Professor and Chair,"Dr. Kapler's broad research interests are concerned with the replication and transmission of eukaryotic chromosomes. The failure to completely replicate the genome during S phase or partially re-replicate chromosomes leads to genome instability- a hallmark of cancer cells. The central questions investigated in the laboratory are concerned with how replication initiation sites are established in chromosomes and how they are regulated during conventional (G1/S/G2/M) and alternative cell cycles, including endoreplication (gap-S-gap-S...) and locus-specific gene amplification. The current focus of the lab is to use high throughput (nascent strand) DNA sequencing to generate a comprehensive map of replication initiation sites under different physiological conditions.",Professor and Chair||Professor,Cell Biology and Genetics||Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n4128afa1
Dzmitry,Kurouski,Assistant Professor,"My laboratory is broadly interested in elucidation of structural organization of amyloid oligomers using Tip-Enhanced Raman Spectroscopy (TERS).
The ultimate objective of our studies is to unravel structural elements on surfaces of amyloid oligomers that are responsible for their toxicity and propensity to propagate into amyloid fibrils. These findings will help to guide pharmaceutical drug screening efforts towards finding selective blockaders of amyloid fibrillation at the stage where their aggregates are minimally toxic. Finally, resolving the structure of amyloid oligomers will give an inside how to cure Alzheimer's and Parkinson's diseases and dementia.",Assistant Professor,Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n43453d43
Gary,Kunkel,Associate Professor,"An important step to control the amount of RNA or protein in particular types of cells is at the level of transcription of genes. Our lab studies a multifunctional vertebrate transcriptional activator protein known as SBF/Staf/ZNF143. This protein binds to SPH sites within promoters of many genes that produce small stable RNAs (e.g., snRNAs and others) PLUS probably over 2000 promoters of genes that produce mRNAs. Two separate activation domains in this protein direct its action at small RNA vs. mRNA gene promoters. We are using zebrafish as a vertebrate model organism to study the roles of SBF/Staf during development. In vivo studies are coupled with biochemical and molecular biology methods to decipher the mechanisms by which this protein stimulates transcription of various types of genes.",Associate Professor,Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n638b96b2