First name,Last name,Preferred title,Overview,Position,Department,Individual
Maria,King,Research Associate Professor,"My interdisciplinary studies focus on the development of the wetted wall cyclone aerosol collector technology to monitor potential health hazards and improve surveillance efforts by collecting aerosols released from agricultural and industrial facilities and modeling particle dispersion. Within a coal mining industry study we aim to determine the influence of particle size distribution, chemical composition and morphology of airborne respirable mine dusts and diesel particulates on lung disease. My projects involve fluid mechanics, computational flow modeling and metagenomics to study biofilms in oil fields and nuclear reactors and mitigate microbial contamination in drilling equipment, hydraulic fracturing water and cooling systems.",Assistant Professor||Faculty Affiliate||Faculty Affiliate,Biological and Agricultural Engineering||Energy Institute||Institute for Engineering Education and Innovation,https://scholars.library.tamu.edu/vivo/display/n44870816
Tadhg,Begley,Distinguished Professor,"The Begley Group is interested in the mechanistic chemistry and enzymology of complex organic transformations, particularly those found on the vitamin biosynthetic pathways. We are currently working on the biosynthesis of thiamin, molybdopterin, pyridoxal phosphate and menaquinone. Our research involves a combination of molecular biology, protein biochemistry, organic synthesis and structural studies and provides a strong training for students interested in understanding the organic chemistry of living systems and in pursuing careers in biotechnology, drug design or academia.
Thiamin pyrophosphate plays a key role in the stabilization of the acyl carbanion synthon in carbohydrate and amino acid metabolism. The biosyntheses of the thiamin pyrimidine and thiazole are complex and are different from any of the characterized chemical or biochemical routes to these heterocycles. We are particularly interested in cellular physiology and the mechanistic enzymology of thiamin biosynthesis. As an example of one of the complex transformations on this pathway, the figure below shows the structure of the pyrimidine synthase catalyzing the complex rearrangement of aminoimidazole ribotide (left) to the thiamin pyrimidine (right).",Distinguished Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n498aa35b