First name,Last name,Preferred title,Overview,Position,Department,Individual
Rajesh,Miranda,Professor,"My research is focused on fetal brain development, stem cells, microRNAs, and teratology. Our laboratory is interested in understanding the biological steps that transform uncommitted stem cells into neurons or a glial cells, and identifying key microRNAs that control the transformation of stem cells into neurons. We are also currently investigating what role teratogen-sensitive microRNAs play in fetal brain growth, and the spatial patterning of the emerging forebrain.",Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n0b271ea8
Douglas,Baxter,Instructional Professor,,Instructional Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n3e6ac00a
David,Earnest,Professor,"Research in my laboratory employs multidisciplinary approaches to study the cellular and molecular neurobiology of cell-autonomous circadian clocks and the signal transduction pathway responsible for circadian photoentrainment. The aims of current projects are to study: 1) the role of microRNAs (miRNAs) and other signaling molecules in the local temporal coordination of cell- and tissue-specific circadian clocks; 2) mutual interactions between the circadian clock mechanism, inflammatory signaling and metabolism; and 3) the mechanisms linking circadian rhythm disruption with metabolic disorders such as obesity and diabetes, and with pathological changes in neuroprotective responses to stroke.",Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n640c528f
Farida,Sohrabji,University Distinguished Professor and Department Head,"My research interests lie at the intersection of neuroendocrinology, neuroinflammation and aging. For the last 10 years, my work has focused on ischemic stroke, specifically, to understand how the aging brain copes with stroke. In North America, stroke risk increases with age and in this aging demographic, women are more likely to sustain a stroke and more likely to have long term disability, poor quality of life and have more neuropsychiatric problems after stroke such as depression and cognitive impairment. This problem is compounded by the fact that few stroke therapies are available. Most stroke neuroprotectants have not been successfully translated from the bench to bedside. Using preclinical models, we have focused on acute pathological changes at the blood brain barrier and central and peripheral inflammation as well as long-term consequences, such as changes to reward pathways and post-stroke depression and dementia. I am also interested in developing novel stroke therapies for stroke in this population and our studies on epigenetic modifications such as histone methylation and non-coding (mi)RNA due to aging/stroke have provided several candidate molecules. Our recent work focuses on the role of the gut microbiome and gut metabolites on stroke recovery, and its potential for understanding the pathophysiology of stroke.
Related to my research goals, I am actively interested in promoting the inclusion of sex as a biological variable and attention to sex differences in medicine. Through medical and graduate coursework, research seminars and community talks, I am a vocal advocate for recognizing sex and gender differences in disease processes and drug therapies. I founded the Women's Health in Neuroscience program at Texas A&M University College of Medicine to create a community of researchers and foster collaboration on gender medicine and women's health, and to train new scholars in this area.",University Distinguished Professor and Department Headd,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n772c9962
Ursula,Winzer-Serhan,Associate Professor,"I am interested in studying how gene environmental interactions shape the brain during development. In particular, I am interested in how early life exposure to psychoactive drugs, like nicotine and alcohol, permanently shape the brain which could result in long-term cognitive impairments, anxiety, and anti-social behavior. My lab is currently focused on the effects of nicotine. Nicotine interacts with nicotinic acetylcholine receptors (nAChR) which are ligand-gated, pentameric cation channels.",Associate Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n7c166c20
Paul,Brandt,Associate Professor,"Understanding how the target cells ""interpret"" hormonal signals is the primary focus of our laboratory.Most of our research centers on regulation of steroid hormone-transduced signals. One area of study is the calcium-dependent regulation of glucocorticoid and androgen receptor-mediated transcription. A second major area of interest concerns glucocorticoid and steroid sex hormone regulation of nitric oxide (NO) production. Other areas of interest in our laboratory are: development of androgen-independence in prostate cancer; stress responses in PMCA1(-) cell lines; and the involvement of NO in dry eye syndrome.",Associate Dean for Academic Technology and Curriculum Innovation||Associate Professor,Neuroscience and Experimental Therapeutics||School of Medicine,https://scholars.library.tamu.edu/vivo/display/nd24a6df6