First name,Last name,Preferred title,Overview,Position,Department,Individual
Benjamin,Neuman,Professor,,Professor,Biology,https://scholars.library.tamu.edu/vivo/display/n193ea580
Terry,Thomas,Professor,"My interests are evolutionarily broad and include animals, plants and fungi. A major focus of the lab is the genomic analysis of gene expression programs during plant gene expression programs, particularly during embryogenesis and seed development, and the underlying regulatory mechanisms required for the initiation and maintenance of these programs. This work has illustrated the combinatorial interactions of cis and trans -acting factors that result in specific gene regulatory events. We are also using genomics tools to study the interaction of the rice blast fungus, Magnaporthe grisea , with plant hosts; the circadian control of gene expression; and the development of the vertebrate retina. An additional focal area is the utilization of molecular and cellular approaches for crop improvement. As part of these research activities, we have developed or adapted high throughput genomics approaches to accelerate the gene discovery process and subsequent analysis of gene expression and function.",Professor,Biology,https://scholars.library.tamu.edu/vivo/display/n79201ac5
Michael,Manson,Professor,"Bacteria have a limited behavioral repertoire. Their most conspicuous behavior is chemotaxis - the pursuit of molecules that are favorable to acquire and the avoidance of chemicals that are best to avoid. The simplicity of bacterial motility and chemotaxis and the amenability of the model species Escherichia coli to genetic, biochemical and physiological manipulation have facilitated rapid advances in understanding the molecular mechanisms of biological energy conversion and signal transduction.
Our laboratory studies the inputs and outputs of chemotaxis. Ligands interact with the periplasmic receptor domain of a chemotactic signal transducer that spans the cell membrane. This interaction is converted into an intracellular signal that is communicated to the flagella. Molecules can be sensed either by binding directly to a receptor or by first interacting with a periplasmic binding protein, which then interacts with a receptor.",Professor||Professor,Biology||Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/ne190242a
Uel,Mcmahan,Professor,"McMahan and his research group provide one of the cornerstones for Texas A&M's new Interdisciplinary Life Sciences Building and its related teaching and research efforts. His work focuses on how the nervous system's synapses form in the embryo and function in the adult in various animal species. It relies on high-resolution imaging, chemical characterization and experimental manipulation of specific macromolecules and organelles, which altogether provide insights unobtainable via any other approach. The findings bear directly on the problems of understanding the molecular basis of human brain diseases and restoring brain function after trauma.",Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nfc3672e7
Matthew,Sachs,Professor,"Understanding the mechanisms by which upstream open reading frames (uORFs) in mRNA transcripts control gene expression is currently the major focus of my laboratory. A substantial component of this work is focused on the uORF-encoded fungal arginine attenuator peptide (AAP). The major goal of this work is to understand the mechanism by which a nascent peptide encoded by this uORF controls the movement of ribosomes on mRNA and regulates gene expression. Control mechanisms mediated by uORFs and nascent peptides exist in mammals, fungi, plants, viruses, and bacteria, but relatively little is known of the molecular details of such control. The AAP is encoded by a uORF in the 5?-leader regions of mRNAs specifying the first enzyme in fungal arginine (Arg) biosynthesis. Synthesis of the AAP rapidly reduces gene expression in response to Arg. AAP-mediated regulation is observed in vivo in both Neurospora crassa and Saccharomyces cerevisiae and in vitro, using fungal, plant and animal extracts. The nascent AAP causes the ribosome to stall when the concentration of Arg is high.",Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nfe74574c