First name,Last name,Preferred title,Overview,Position,Department,Individual
Andy,Thomas,Assistant Professor,"Our primary research objective is to develop new methods by investigating and harnessing the reactivity of highly unstable intermediates. Essential to improving mechanistic understanding is the development of new strategies that allow us to monitor fleeting intermediates and manipulate their reactivity. To supplement our mechanism driven methodology development, we will develop a new rapid multiple injection NMR (RMI-NMR) system to monitor and control the reactivity of transient species. Representative areas of research interest include the development of new organic transformations; and the development of catalyst-transfer polymerization reactions.",Assistant Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n07836ca1
Daniel,Tabor,Assistant Professor,,Assistant Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n3fb1c10e
Quentin,Michaudel,Assistant Professor,,Assistant Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n83f25144
Matthew,Sheldon,Assistant Professor,"Our research considers fundamental questions of optical energy conversion relating to plasmonic and inorganic nanoscale materials. Our experiments are principally designed to identify and optimize unique nanoscale phenomena useful for solar energy conversion, as well as related opportunities at the intersection of nanophotonics and chemistry. We employ optical and electrical characterization techniques with high spatial and energy resolution to probe optical excitation and relaxation mechanisms in nanostructured metals and semiconductors.
The current world record solar cell operates at 44.4% power conversion efficiency. Thermodynamic analyses indicate that much higher efficiency is theoretically possible. Indeed, technical challenges, rather than laws of nature, limit current solar power convertors from achieving the maximum thermodynamic efficiency of 95%.
We seek to better understand how nanofabricated optoelectronic and plasmonic materials provide a route to achieve the maximum possible conversion efficiency with solid state and photoelectrochemical systems. We explore how nanostructuring materials enables systematic control of the thermodynamic parameters governing optical power conversion, enabling optimization that can shape, confine, and interconvert the energy and entropy of a radiation field. Additionally, the remarkable nanoscale tailorability of a variety of structural properties, such as electrochemical potential, can further enable novel photochemical systems with broad application beyond the scope solar energy conversion.
We seek students who are interested to gain expertise in inorganic synthesis of nanocrystals with tunable electrochemical and optical structures, nanofabrication, and comprehensive characterization and modeling of optoelectronic structures. Particular emphases are optical absorption and fluorescence spectroscopy, photovoltaic device physics, nanoscale electrical characterization, scanning probe techniques, and optical simula",Faculty Affiliate||Assistant Professor,Energy Institute||Chemistry,https://scholars.library.tamu.edu/vivo/display/nb887f9b0
Xin,Yan,Assistant Professor,"At the Yan lab, we seek to develop and apply novel mass spectrometric methodologies in disease diagnosis, reaction monitoring, and development of new synthetic methods. In particular, we are motivated by the possibility of enabling new technology for next-generation approaches to precision medicine, and sustainable synthesis.
Our research interests span a range of topics, including i) metabolomics in brain research: we couple dual imaging modality (mass spectrometry imaging and fluorescence imaging) with liquid chromatography mass spectrometry to discover biomarkers and elucidate their biological mechanism in brain aging and brain cancer research. ii) point-of-care diagnostics: we are interested in the development of ambient ionization for fast analysis of enzymatic biomarkers, as well as the design and development of the interface to mini-mass spectrometer (mini-MS) for point-of-care diagnosis. iii) microdroplet reaction: mass spectrometry is universally considered as an analytical tool, however, its new feature was discovered: its use as a unique tool in synthesis. The uniqueness represents in its capabilities of dramatical acceleration of organic reactions and the driving of reactions that cannot occur in bulk. We aim to develop microdroplet reactors for acceleration, explore new reactivity, and study fundamentals of microdroplet acceleration. iv) reaction mechanistic study: reaction mechanisms play an essential role in the study of organic chemistry. We aim to develop new online mass spectrometric reaction monitoring system to explore unknown reaction mechanism, capture short-lived intermediates, study kinetics of fast reactions, and control process of active pharmaceutical ingredient (API) synthesis. The central theme of all the topics above is about droplet chemistry.
This lab is a highly interdisciplinary research group. It provides students the opportunity to obtain hands-on experience in analytical, biological and synthetic chemistry.",Assistant Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/nc863cc6e
Jonathan,Sczepanski,Assistant Professor,"Our primary research goals are to develop and apply novel tools for studying DNA damage in the context of chromatin and to explore new avenues for RNA-based therapeutics and diagnostics. By combining expertise in chemical biology, molecular biology, and molecular evolution, our lab addresses challenges associated with studying and targeting noncoding RNAs from a unique perspective. In addition, we utilize modern chemical biology techniques to develop designer chromatin systems for studying DNA damage. We are seeking motivated individuals who wish to gain experience in chemical biology, molecular biology, and in vitro evolution techniques.",Assistant Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/ncc157d6e
Shiqing,Xu,Assistant Professor,"Our research aims to develop innovative synthetic methodologies and therapeutic approaches, and apply them to solving pressing problems of biological and medical importance. New synthetic methodologies and strategies (e.g. non-traditional disconnections and C-H functionalization) have great impacts on the discovery of transformational medicines by enabling the rapid and efficient synthesis of novel, diverse, and complex biologically active molecules. New therapeutic approaches (e.g. targeted covalent inhibition and targeted protein degradation) provide new opportunities to address traditionally ""undruggable"" disease targets.
We anticipate that the combination of the efforts in the development of novel synthetic methodologies and therapeutic approaches will advance drug discovery in diseases of unmet need, and achieve the research goal of identifying small-molecule probes and drug candidates that specifically remove/inhibit disease-causing proteins in cells and animal models and ultimately impact human health. Representative research directions include:
1. COVID-19 drug discovery via small-molecule-induced targeted protein inhibition and degradation
2. Late-stage functionalization of drugs and peptides & its applications in drug discovery
3. Organoboron chemistry and its medical applications",Assistant Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/ncd983c6e