First name,Last name,Preferred title,Overview,Position,Department,Individual
Raymond,Carroll,Distinguished Professor,,Distinguished Professor,Statistics,https://scholars.library.tamu.edu/vivo/display/n032647a0
John,Gladysz,Distinguished Professor,"My research has traditionally been centered around organometallic chemistry, and from this core area branches into catalysis, organic synthesis, enantioselective reactions, stereochemistry, mechanism, and materials chemistry. About half of my group is involved with catalysis projects. Areas receiving emphasis include (a) structurally novel new families of highly enantioselective catalysts, (b) metal-containing ""organocatalysts"" and (c) recoverable catalysts, particularly those with ""ponytails"" of the formula (CH2)m(CF2)nF; these can be recycled via ""fluorous"" liquid or solid phases, such as Teflon. The other half of my group synthesizes organometallic building blocks for molecular devices. These include (a) molecular wires composed of metal endgroups and linear (sp) carbon chains, including stable species with C28 bridges, (b) analogs in which the charge-transmitting bridges are insulated by a pair of polymethylene or (CH2)n chains that adopt a double-helical conformation, (c) polygons and multistranded molecular wires based upon such building blocks, and (d) molecular gyroscopes and compasses consisting of a rotating MLn fragment and an external cage (stator) that insulates the rotator from neighboring molecules, exactly as with the commercial gyroscopes used for aircraft and space-station navigation.",Faculty Affiliate||Distinguished Professor,Energy Institute||Chemistry,https://scholars.library.tamu.edu/vivo/display/n05e5403e
Donald,Darensbourg,Distinguished Professor,"The fundamentally interesting and challenging chemistry associated with carbon dioxide, coupled with its high potential as a source of chemical carbon, provides adequate justification for comprehensive investigations in this area. In our research program we have attempted to establish a clearer mechanistic view of carbon-hydrogen, carbon-carbon, and carbon-oxygen bond forming processes resulting from carbon dioxide insertion into M-H, M-C, and M-O bonds.
Relevant to the latter process our research has addressed the utilization of carbon dioxide in the development of improved synthetic routes for the production of polycarbonates. The hazardous and expensive production process currently in place industrially for these materials involves the interfacial polycondensation of phosgene and diols, accentuates the need for these studies. Although we and others have made significant advances in the synthesis of these useful thermoplastics from carbon dioxide and epoxides much of the fundamental knowledge concerning the reaction kinetics of these processes is lacking, due in part to the practical challenges associated with sampling and analyzing systems at elevated temperatures and pressures. This information is needed for making this process applicable to the synthesis of a variety of copolymers possessing a range of properties and uses. Our studies are examining in detail the mechanistic aspects of metal catalyzed carbon dioxide/epoxide coupling reactions employing in situ spectroscopy methods. For this purpose Fourier-transform infrared attenuated total refluctance (FTIR/ATR) spectroscopy is being utilized. Other related investigations involve the development of structural and reactivity models for the industrially prevalent double metal cyanide catalysts(DMC) used in polyethers and polycarbonate synthesis from epoxides or CO2/epoxides, respectively.",Distinguished Professor||Faculty Affiliate,Energy Institute||Chemistry,https://scholars.library.tamu.edu/vivo/display/n06bf3bf8
David,Lee,Distinguished Professor,"Liquid and Solid Helium, Spin Polarized Hydrogen Gas, Superconductivity, Magnetic Resonance, Impurity-Helium Solids, Solid Hydrogen.",Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/n0796fad3
John,Crompton,Distinguished Professor,,Distinguished Professor,"Hospitality, Hotel Management and Tourism",https://scholars.library.tamu.edu/vivo/display/n0cd50a6b
James,Womack,Distinguished Professor,"Comparative mammalian genomics with emphasis on bovids and laboratory animals. Study of evolution of gene families and genomic variation underlying disease resistance. Investigation of genetic mechanisms in innate immunity with focus on livestock, select agents, and agricultural biosecurity.",Distinguished Professor,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/n0e1a49e2
Guoyao,Wu,Distinguished Professor,"Dr. Wu teaches graduate courses in protein metabolism and nutritional biochemistry. He conducts research in protein and amino acid metabolism at molecular, cellular, and whole body levels . The animal models used in his research include cattle, chicks, pigs, rats, sheep, fish, and shrimp. He has also conducted research on amino acid nutrition in humans.",Faculty Fellow||University Faculty Fellow||Distinguished Professor||Senior Faculty Fellow||Distinguished Professor,Veterinary Integrative Biosciences||Animal Science||Texas A&M AgriLife Research||Texas A&M AgriLife Research||Nutrition,https://scholars.library.tamu.edu/vivo/display/n169f9a74
Ricky,Griffin,Distinguished Professor,"My research interests include informal leadership, workplace aggression and violence, organizational security, and workplace culture.",Distinguished Professor,Management,https://scholars.library.tamu.edu/vivo/display/n23b10066
Jeffrey,Savell,Distinguished Professor,,Distinguished Professor,Animal Science,https://scholars.library.tamu.edu/vivo/display/n2a814ea8
Peter,Santschi,Distinguished Professor,"Research interests include a broad range of topics in Marine and Environmental Chemistry, including the role of natural nanoparticles in the biogeochemical cycling of trace substances, tracer applications using radioactive and stable isotopes, relationships between trace element and natural organic matter biogeochemistry, and the importance of exopolymeric substances and hydroxamate siderophores for trace element binding and removal from natural waters. That involves learning from new techniques, approaches and concepts that are used in related fields and applying them to solve questions in biogeochemistry and environmental science. Current themes of research are: Trace element speciation and cycling. Tracer applications in natural water systems using stable and radioactive isotopes. Sediment-water and particle-water interactions, with emphasis on colloids. Natural organic matter geochemistry. Metal-organic matter binding. Mobility of radioactive and toxic trace contaminants in surface waters, sediments and ground water. Applications of atomic force microscopy, accelerator, thermal ionization, and gas chromatography mass spectrometry in marine and environmental chemistry and geochemistry.",Distinguished Professor,Marine Sciences,https://scholars.library.tamu.edu/vivo/display/n2b3d402d
Olga,Kocharovskaya,Distinguished Professor,,Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/n3024ca95
Peter,Kuchment,Distinguished Professor,"Major research articles, books, surveys, and presentations around the world on inverse problems (with applications to medical and homeland security imaging), material science (photonic crystals, nanostructures), spectral theory 9with math physics applications), and quantum graphs.",Distinguished Professor,Mathematics,https://scholars.library.tamu.edu/vivo/display/n3d473146
Robert,Chapkin,Distinguished Professor,"Research in the Chapkin lab focuses on dietary/microbial modulators related to the prevention of cancer and chronic inflammatory diseases.
Our central goal is to (1) understand cancer chemoprevention at a fundamental level, and (2) to test pharmaceutical agents in combination with dietary/microbial (countermeasures to the Western diet) to more effectively improve gut health and reduce systemic chronic inflammation. Since diet influences gut microbiota composition and metabolite production, to unravel the interrelationships among gut health and the structure of the gut microbial ecosystem, we are in the process of evaluating (using transgenic mouse, Drosophila models and humans) how the gut microbiome modulates intestinal cells, innate immune cells and tumors. As part of this endeavor, we are modeling at the molecular level the dynamic relationship between diet and gut microbe-derived metabolites which modulate chronic inflammation and the hierarchical cellular organization of the intestine, e.g., stem cell niche.",Distinguished Professor||Professor,Biochemistry and Biophysics||Nutrition,https://scholars.library.tamu.edu/vivo/display/n3fbb59f8
Tadhg,Begley,Distinguished Professor,"The Begley Group is interested in the mechanistic chemistry and enzymology of complex organic transformations, particularly those found on the vitamin biosynthetic pathways. We are currently working on the biosynthesis of thiamin, molybdopterin, pyridoxal phosphate and menaquinone. Our research involves a combination of molecular biology, protein biochemistry, organic synthesis and structural studies and provides a strong training for students interested in understanding the organic chemistry of living systems and in pursuing careers in biotechnology, drug design or academia.
Thiamin pyrophosphate plays a key role in the stabilization of the acyl carbanion synthon in carbohydrate and amino acid metabolism. The biosyntheses of the thiamin pyrimidine and thiazole are complex and are different from any of the characterized chemical or biochemical routes to these heterocycles. We are particularly interested in cellular physiology and the mechanistic enzymology of thiamin biosynthesis. As an example of one of the complex transformations on this pathway, the figure below shows the structure of the pyrimidine synthase catalyzing the complex rearrangement of aminoimidazole ribotide (left) to the thiamin pyrimidine (right).",Distinguished Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n498aa35b
Margaret,Ezell,Distinguished Professor,"My interests are late seventeenth and early eighteenth-century literary culture; early modern women writers; history of authorship, reading and handwritten culture; early modern social media and multi-modal literacy",John and Sara Lindsey Chair||Distinguished Professor,English||College of Liberal Arts,https://scholars.library.tamu.edu/vivo/display/n51a1a457
Thomas,Saving,Distinguished Professor,,Distinguished Professor,Economics,https://scholars.library.tamu.edu/vivo/display/n58e1f258
Gilles,Pisier,Distinguished Professor,,Distinguished Professor,Mathematics,https://scholars.library.tamu.edu/vivo/display/n5cb5907b
Chanan,Singh,Distinguished Professor,"My research focuses on reliability and security of electric power systems, theory and applications of system reliability, production costing, and power quality.",Faculty Affiliate||Distinguished Professor,Energy Institute||Electrical and Computer Engineering,https://scholars.library.tamu.edu/vivo/display/n5cf92600
Akhil,Dattagupta,Distinguished Professor,"I have research interests in rapid flow simulation techniques, reservoir optimization, large-scale parameter estimation via inverse methods and uncertainty quantification/ assessments.",Distinguished Professor,Petroleum Engineering,https://scholars.library.tamu.edu/vivo/display/n5e728236
Je-Chin,Han,Distinguished Professor,"My research focuses on thermal Fluid Sciences - heat transfer and cooling in gas turbines, heat transfer enhancement, heat transfer in rotating flows, film cooling in unsteady high turbulent flows, combustor-liner cooling, mini-channel heat transfer, advanced CFD and experimental methods.",Distinguished Professor||Faculty Affiliate,Mechanical Engineering||Energy Institute,https://scholars.library.tamu.edu/vivo/display/n66dced6c
Abraham,Clearfield,Distinguished Professor,"Our research interests are focused in solid state and materials chemistry and encompass a wide variety of projects. An important goal is the ability to design and synthesize new materials whose structure and properties can be predicted and controlled. Layered compounds are amenable to manipulation to produce new structures because of the weak forces between layers. We have learned how to separate the layers of several classes of compounds and are reconstituting them into novel materials. For example, we have prepared staged materials in which alternating layers are hydrophobic and hydrophilic.
The surfaces of our layered materials react with a variety of molecules to bond them to the surface. We are developing such materials for drug delivery, heterogeneous catalysis, and polymer-nanoparticle composites.
Single crystal X-ray diffraction has been the key tool in elucidating the structure of solids. For many compounds, single crystals are unavailable so that indirect methods need to be used. We pioneered the solution of crystal structures from X-ray powder data and have had considerable success. The methods need to be improved and extended to more complex systems such as poorly crystallized materials. Combined use of X-ray, neutron and synchrotron methods are in progress and extension to EXAFS and amorphous scattering techniques is contemplated.",Distinguished Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n6dc4bd81
Marcetta,Darensbourg,Distinguished Professor,"Bio-inspired Catalysts for Hydrogen Production: The ultimate, home-run, goal of our work is to synthesize and develop a robust, highly active hydrogen-producing catalyst comprised of earth-abundant transition metals within a ligand environment that is inspired by the biological Figure 3hydrogenase (H2ase) enzyme active sites. Progress in precise structural modeling of the illusive ""rotated"" structure displayed in the as-isolated, mixed-valent FeIIFe state in the past decade has permitted in depth analysis of electronic structure by Mo ssbauer, EPR (ENDOR), and computational chemistry. New electrocatalysts for hydrogen production: The connection between the Fe(NO)2 unit and the Fe(CX)3 (X = O or N) unit found in hydrogenase enzyme active sites offers opportunity for design of new catalysts, one of which is shown. In this regard we explore the ability of N2S2 metal complexes to bind as metallodithiolate ligands to various metal acceptors. The properties of such complexes vary The connection of these to light harvesting molecules for dye sensitized, sacrificial electron donor, hydrogen production is also of interest. When Iron Meets Nitric Oxide: Good Chemistry, Intriguing Biology. The affinity of iron for diatomic molecules, O2, CO, N2, and NO, is central to the most important of life processes, including those of human physiology. Figure 6In this research area we target synthetic chemistry involving dinitrosyl iron complexes (DNICs) that serve as biomimetics of products of FeS cluster degradation by excesses of NO, or as derived from the chelatable iron pool (CIP) in cells. The electronic ambivalence of the DNIC unit is expressed in the ease with which it interconverts between oxidized and reduced forms, {Fe(NO)2}9 and {Fe(NO)2}10, respectively (Enemark/Feltham notation), and serves as impetus to explore analogous reactions known to involve the CuII/CuI redox couple. The accessory ligands which stabilize one redox level over the other, including N-heterocyclic carb",Distinguished Professor||Faculty Affiliate,Energy Institute||Chemistry,https://scholars.library.tamu.edu/vivo/display/n6f445741
Ignacio,Rodriguez-Iturbe,Distinguished Professor,"My research focuses on coastal ecosystems, hydrogeomorphology, ecohydrology, river basin functioning and organization, and stochastic modelling of natural phenomena.",Distinguished Research Professor||Distinguished Professor,Texas A&M Engineering Experiment Station (TEES)||Ocean Engineering,https://scholars.library.tamu.edu/vivo/display/n74fab617
Roderick,Dashwood,University Distinguished Professor,"Research integrates multiomic, genetic, epigenetic and immune approaches for precision oncology. Epigenetic readers, writers and erasers that reversibly regulate immune players in the antigen presentation pathway are of current mechanistic interest. Molecular and cell-based assays are combined with preclinical models coupled to polypectomy. Clinical specimens and organoids from patients undergoing colectomy provide for human translation. Supported by the NCI, NINDS/NIA, and the John S. Dunn Foundation.",John S. Dunn Chair in Disease Prevention||Distinguished Professor||Director,Institute of Biosciences and Technology||Center for Epigenetics and Disease Prevention||School of Medicine,https://scholars.library.tamu.edu/vivo/display/n7a63dbe7
Fuller,Bazer,Distinguished Professor,"Dr. Bazer's research in reproductive biology focuses on uterine biology and pregnancy, particularly pregnancy recognition signaling from the conceptus to the maternal uterus by interferon tau and estrogen from ruminant and pig conceptuses, respectively. The roles of uterine secretions as transport proteins, regulatory molecules, growth factors and enzymes and endocrine regulation of their secretion is another major research interest. The endocrinology of pregnancy, especially the roles of lactogenic and growth hormones in fetal-placental development and uterine functions are being studied. The mechanism(s) of action and potential therapeutic value of conceptus interferons and uterine-derived hematopoietic growth factors are areas of research with both pigs and sheep as models for human disease.",Distinguished Professor,Animal Science,https://scholars.library.tamu.edu/vivo/display/n7ad91d50
Ronald,Devore,Distinguished Professor,,Distinguished Professor,Mathematics,https://scholars.library.tamu.edu/vivo/display/n7bb081e2
Karen,Wooley,Distinguished Professor,"Our research activities combine organic syntheses, polymerization strategies and polymer modification reactions in creative ways to afford unique macromolecular structures, which have been designed as functional nanostructures, polymer systems having unique macromolecular architectures, and/or degradable polymers. The emphasis is upon the incorporation of functions and functionalities into selective regions of polymer frameworks. In some cases, the function is added at the small molecule, monomer, stage, prior to polymerization, whereas, in other cases, chemical modifications are performed upon polymers or at the nanostructure level; each requires a strategic balance of chemical reactivity and the ultimate composition and structure.",Distinguished Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/n7d5d2fbd
Kumbakonam,Rajagopal,Distinguished Professor,My research focuses on Continuum mechanics and its applications to Non-linear materials.,Distinguished Professor,Mechanical Engineering,https://scholars.library.tamu.edu/vivo/display/n7e7a53ce
Christopher,Pope,Distinguished Professor,"Dr. Pope's research interests include:theoretical high-energy particle physics; unification of the fundamental interactions in nature; general relativity, quantum gravity, supergravity; superstring theories; conformal field theory; extended higher-spin theories; applications of differential geometry and topology in physics.",Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/n7fbdaa30
Murray,Barrick,Distinguished Professor,My research focuses on the impact individual differences in behavior and personality have on job performance and on methods of measuring and predicting such differences.,Distinguished Professor,Management,https://scholars.library.tamu.edu/vivo/display/n84e4299a
William,Saric,Distinguished Professor,,Distinguished Professor,Aerospace Engineering,https://scholars.library.tamu.edu/vivo/display/n86d8d0f1
John,Hardy,Distinguished Professor,,Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/n9205043b
Bruce,Mccarl,Distinguished Professor,"Dr. McCarl's recent research efforts have largely involved policy analysis (mainly in climate change, climate change mitigation, water economics, and biosecurity) as well as the proper application of quantitative methods to such analyses. He teaches graduate courses in applied mathematical programming and applied risk analysis. He was part of the 2007 Nobel Peace Prize winning Intergovernmental Panel on Climate Change.",Faculty Affiliate||Distinguished Professor,Energy Institute||Agricultural Economics,https://scholars.library.tamu.edu/vivo/display/n9596bd48
Rostislav,Grigorchuk,Distinguished Professor,"My research focuses on Group Theory, Dynamical Systems, Low dimensional Topology, Discrete Mathematics, Abstract Harmonic Analysis, Random Walks, Invariant Means, Bounded Cohomology, and L2-invariants.",Distinguished Professor,Mathematics,https://scholars.library.tamu.edu/vivo/display/n9b548597
Marlan,Scully,Distinguished Professor,,Distinguished Professor||Faculty Affiliate,Physics and Astronomy||Energy Institute,https://scholars.library.tamu.edu/vivo/display/na2a37577
Bani,Mallick,Distinguished Professor,"Bayesian hierarchical Modeling, Nonparametric Regression and classification, Bioinformatics, Spatio-temporal Modeling, Machine learning, Functional Data analysis, Bayesian nonparametrics, Petroleum reservoir characterization, Uncertainty analysis of Computer Model outputs",Distinguished Professor,Statistics,https://scholars.library.tamu.edu/vivo/display/na73654e3
Dimitri,Nanopoulos,Distinguished Professor,,Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/na8423a0a
Frank,Raushel,Distinguished Professor,"Enzymes catalyze a remarkable variety of chemical reactions with extremely high rate enhancements and very selective substrate specificity. The research efforts in our laboratory are directed towards a more complete understanding of the fundamental principles involved in enzyme-catalyzed chemistry and the dependence on protein structure. The pursuit of this information will provide the framework for the rational and combinatorial redesign of these complex molecules in an effort to exploit and develop the properties of enzyme active sites for a variety of chemical, biological, and medicinal uses. The techniques that we are using to solve these problems include steady-state and stopped-flow kinetics, NMR and EPR spectroscopy, X-ray crystallography, and the synthesis of inhibitors and suicide substrates. We are also using recombinant DNA methods to construct new proteins with novel catalytic properties. These efforts are currently being directed to the reactions catalyzed by phosphotriesterase and enzymes involves in the degradation of lignin and the metabolism of novel carbohydrates from the human gut microbiome.
The phosphotriesterase enzyme catalyzes the hydrolysis of organophosphate insecticides and other toxic organophosphate nerve agents. We have discovered that the active site of this protein consists of a unique binuclear metal center for the activation of water. We are now investigating the structure and properties of this metal center as a model system for the evolution of enzyme structure and function. Toward this end we have mutated the active site of this enzyme in a research project to create novel enzymes with the ability to detect, destroy, and detoxify various chemical warfare agents such as sarin, soman, and VX. The Raushel laboratory is also engaged in a large scale research project that is focused on the development of novel strategies for the discovery of new enzymes.",Distinguished Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/na84f2fec
M. Katherine,Banks,President,,President||Distinguished Professor,Civil Engineering||Office of the President,https://scholars.library.tamu.edu/vivo/display/na92cc165
Kenneth,Meier,Distinguished Professor,,Distinguished Professor,Political Science,https://scholars.library.tamu.edu/vivo/display/nb1d7a363
Stephen,Safe,Distinguished Professor,The aryl hydrocarbon receptor (AhR) is a nuclear helix-loop-helix transcription factor which forms a ligand-induced nuclear heterodimer with the AhR nuclear translocator (Arnt) protein. Research in this laboratory is focused on the molecular mechanism of crosstalk between the AhR and estrogen receptor (ER) signaling pathways in which the AhR inhibits estrogen-induced gene expression. The antiestrogenic activities of some AhR agonists are also being developed as drugs for clinical treatment of breast and endometrial cancers in women. Research on estrogen-dependent gene expression in various cancer cell lines is focused on analysis of several gene promoters to determine the mechanisms of ERa and ERb action. This includes several genes that are activated through interactions of the ER with Sp1 protein and other DNA-bound transcription factors.,Distinguished Professor||Distinguished Professor||Syd Kyle Chair,School of Veterinary Medicine and Biomedical Sciences||Biochemistry and Biophysics||Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/nb20fdbd9
George,Edwards,Distinguished Professor,,Distinguished Professor,Political Science,https://scholars.library.tamu.edu/vivo/display/nb7a2dc96
B. Don,Russell,Distinguished Professor,"My research interests include electric power engineering, power system protection, control and automation of power systems, power systems diagnostics and waveform analytics, forensic engineering, engineering ethics, and engineering professionalism.",Faculty Affiliate||Distinguished Professor,Energy Institute||Electrical and Computer Engineering,https://scholars.library.tamu.edu/vivo/display/nc3a5baa9
Edward,Fry,Distinguished Professor,,Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/nc6032fda
Valery,Pokrovsky,Distinguished Professor,,Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/ncd49eb9c
Panganamala,Kumar,Distinguished Professor,"I have worked on problems in game theory, adaptive control, stochastic systems, simulated annealing, neural networks, machine learning, queueing networks, manufacturing systems, scheduling, wafer fabrication plants and information theory. My research is currently focused on energy systems, wireless networks, secure networking, automated transportation, and cyberphysical systems.",Distinguished Professor,Electrical and Computer Engineering,https://scholars.library.tamu.edu/vivo/display/nd0f11408
Rajan,Varadarajan,Distinguished Professor,"My primary teaching and research interests are in the areas of marketing strategy, innovation, international marketing and environmental sustainability.",Distinguished Professor,Marketing,https://scholars.library.tamu.edu/vivo/display/nd16e4c71
Robert,Tribble,Distinguished Professor,,Distinguished Professor,Physics and Astronomy,https://scholars.library.tamu.edu/vivo/display/nd86adc93
Kim,Dunbar,Distinguished Professor,"Research in the Dunbar group spans topics in synthetic, structural and physical inorganic and bioinorganic chemistry. The use of a range of tools including spectroscopy, X-ray crystallography, magnetometry, electron microscopy, mass spectrometry and electrochemistry reflect the breadth of problems under investigation.",Distinguished Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/ndd473437
Larry,Reynolds,University Distinguished Professor,"My name is Larry J. Reynolds, and my work is focused on Nineteenth-Century American Literature and Culture. My books may be found at:
https://www.amazon.com/kindle-dbs/entity/author/B001HD3GJQ?_encoding=UTF8&node=283155&offset=0&pageSize=12&searchAlias=stripbooks&sort=author-sidecar-rank&page=1&langFilter=default#formatSelectorHeader",Distinguished Professor,English,https://scholars.library.tamu.edu/vivo/display/ne0d2f5f7
Robert,Ireland,University Distinguished Professor and Executive Associate Dean,,Distinguished Professor||Executive Associate Dean,Management||Mays Business School,https://scholars.library.tamu.edu/vivo/display/nef426b3a
Paul,Hardin,Distinguished Professor,"A diverse array of organisms including prokaryotic and eukaryotic microbes, plants, and animals display daily rhythms in physiology, metabolism and/or behavior. These rhythms are not passively driven by environmental cycles of light and temperature, but are actively controlled by endogenous circadian clocks that are set by environmental cycles, keep time in the absence of environmental cues, and activate overt physiological, metabolic and behavioral rhythms at the appropriate time of day. This remarkable conservation of circadian clock function through evolution suggests that maintaining synchrony with the environment is of fundamental importance. Our understanding of the circadian clock is particularly important for human health and well-being. The clearest examples of circadian clock dysfunction are those that result in abnormal sleep-wake cycles, but clock disturbances are also associated with other ailments including epilepsy, cerebrovascular disease, depression, and seasonal affective disorder. The realization that disorders of the sleep-wake cycle such as Familial Advanced Sleep Phase Syndrome can result from alterations in clock gene function underscores the clinical importance of understanding the molecular organization of the circadian system.
Work in my laboratory focuses on defining the molecular mechanisms that drive circadian clock function in the fruit fly, Drosophila melanogaster. We previously found that the core timekeeping mechanism is based on core and interlocked transcriptional feedback loops. Our studies currently focus on (1) defining post-translational regulatory mechanisms that operate in the core loop to set the 24 hour period, (2) determining whether interlocked loops are important for circadian timekeeping and/or output, (3) understanding how circadian oscillator cells are determined during development, and (4) defining mechanisms that control rhythms in olfactory and gustatory physiology and behavior.",Distinguished Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nf27056c4
Junuthula,Reddy,Distinguished Professor and O'Donnell Foundation Chair IV,"The current research of Dr. Reddy and his group deals with refined shell theories and associated robust shell finite elements which are free of all types of locking, and nonlocal beam and plate theories using the ideas of Eringen, Mindlin, Koiter, and others (in collaboration with colleagues from China, Finland, France, India, Singapore, Spain). He and his group has developed a thermodynamically based strain gradient elasticity theory that contains Mindlin's model as a special case. They also conceived a transformative non-parametric network based methodology to study damage and fracture in solids (GraFEA), which yields mesh independent results for fracture and its propagation and it does not require user input about the possible fracture initiation and propagation. His works on nonlocal mechanics ideas and their incorporation into structural theories to predict the bending, buckling, and vibration response (the main idea is to embed micropolarity, which brings an additional layer of kinematics through the micro-rotation degrees of freedom within a continuum model to account for the microstructural effects during deformation to study architected materials and structures) and graph-based finite elements to predict damage and fracture are receiving attention of fellow researchers around the world. His shear deformation plate and shell theories and their finite element models and the penalty finite element models of non-Newtonian fluids have been implemented into commercial finite element computer programs like ABAQUS, NISA, and HyperXtrude.",Regents Professor||Distinguished Professor||Faculty Affiliate,The Texas A&M University System||Mechanical Engineering||Energy Institute,https://scholars.library.tamu.edu/vivo/display/nf2ea2ce4
William,Johnson,Distinguished Professor,,Distinguished Professor,Mathematics,https://scholars.library.tamu.edu/vivo/display/nf383dcb8
Richard,Gomer,Distinguished Professor,"Our laboratory is working on three areas of biomedicine, trying to move observations from basic research into the clinic. First, we are studying how the sizes of tissues and tumors are regulated, and how this can be manipulated for therapeutic purposes. As a model system, we are using the simple eukaryote Dictyostelium discoideum, which allows us to combine techniques such as biochemistry, genetics, computer modeling, and cell biology to study tissue size regulation. We have found that a secreted protein as well as the unusual molecule polyphosphate are signals in negative feedback loops that inhibit Dictyostelium cell proliferation, and we are studying the signal transduction pathway to understand similar mechanisms in humans.
Second, we are studying how some secreted proteins can make cells move away from the source of the signal. We found such a signal (called a chemorepellent) in Dictyostelium, and then found a similar signal in humans. We are working to understand the signal transduction pathway for both. The human signal repels neutrophils, and we found that this can be used therapeutically in mouse models of neutrophil-driven diseases such as rheumatoid arthritis and acute respiratory distress syndrome.
Third, we have found that a human blood protein called Serum Amyloid P (SAP) regulates a key step in the formation of scar tissue as well as the formation of the scar-like lesions in fibrosing diseases such as congestive heart failure and pulmonary fibrosis. We are studying this mechanism, and a biotech company (Promedior, now sold to Roche) we co-founded is testing SAP as a therapy for fibrosis in patients in a Phase 3 trials.",Distinguished Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nf41f3898
Edward,Dougherty,Distinguished Professor,My research focuses on genomic signal processing and image analysis.,Distinguished Professor,Electrical and Computer Engineering,https://scholars.library.tamu.edu/vivo/display/nf4ef0ac5