First name,Last name,Preferred title,Overview,Position,Department,Individual
Karuppiah,Chockalingam,Research Assistant Professor,,Research Assistant Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n015218cf
James,Samuel,Regents Professor and Head,"Our laboratory works with the obligate intracellular bacterial pathogen, Coxiella burnetii, the etiologic agent of Q fever and a category B biothreat agent. The long-term goal of this research is to understand the molecular pathogenic mechanisms involved in the host-pathogen interaction. To accomplish this broad goal, project in the lab are designed to test the molecular mechanisms employed by both the host and pathogen. Current pathogen studies include 1) broad survey of proteins secreted via a type 4 secretion system (T4SS) followed by determination of essentiality of each substrate for virulence and detailed analysis of mechanism of host modulation 2) survey of essential virulence loci identified by specific mutant screens, and 3) definition of the relative virulence of phylogenetically distinct isolate groups.",Regents Professor and Head,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n01c3216f
Carolyn,Cannon,Associate Professor,"Our goal is to develop novel, non-toxic antimicrobial formualtions with efficacy against gram-positive and gram-negative multi-drug resistant pathogens.",Associate Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n0b3870aa
Erin,Van Schaik,Research Assistant Professor,,Research Assistant Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n0f17ac3a
Alistair,McGregor,Associate Professor,"Our lab studies various herpesviruses but the major focus of our research is on the study of cytomegalovirus (CMV) which is a common pathogen that establish a life long infection in a mainly latent state. CMV causes disease in transplant patients and is a leading cause of congenital disease in newborns where the virus crosses the placenta and infects the fetus in utero. Congenitally infected newborns can have severe disease that causes cognitive impairment, hearing loss and vision problems. There is no vaccine against congenital CMV and our research seeks to understand the disease and develop interventions strategies.",Associate Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n3de7f8e8
Jianxun,Song,Professor,T cell biology
T cell-based immunotherapy
Cell metabolism,Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n5b9879a8
A. Phillip,West,Assistant Professor,"Mitochondria are complex and dynamic organelles integral to many processes including energy generation, programmed cell death, signal transduction, and immunity. Research in my laboratory centers on understanding how mitochondria regulate innate immunity and inflammatory processes to influence human health and disease.",Assistant Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n739a434b
David,Huston,Professor,The overall goal of my laboratory is to understand mechanisms regulating inflammation and thereby develop strategies for modulating immune responses. One project focuses on the role of the cytokine thymic stromal lymphopoietin (TSLP) as the master switch in the pathobiology of allergic inflammation and asthma. The role of allergens and respiratory viruses on the induction of TSLP transcription by mast cells and epithelial cells is being studied in vitro and in human subjects.,Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/nbd68089f
Robert,Watson,Assistant Professor,"We are interested in the interface between intracellular bacterial pathogens and the hosts they infect. In particular, we study the notorious human pathogen, Mycbacterium tuberculosis, which remains a major global health threat. M. tuberculosis has evolved a variety of specific adaptations to not only survive but also replicate within the harsh environment inside a macrophage. We want to understand the mechanisms by which M. tuberculosis is able to modulate the innate immune response to establish an infection as well as how the host detects and responds to M. tuberculosis.",Assistant Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/nc0edc59a
Vernon,Tesh,Professor,,Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/nc2165f28
Zhilei,Chen,Associate Professor,"The Chen Medicinal Protein Lab aims to accelerate the discovery, development and clinical translation of protein therapeutics through innovative protein engineering research. We believe that better medicine enables a higher quality of living, and protein engineers are charged to create the better medicine for today and tomorrow. We are particularly interested in the creation and engineering of affordable protein therapeutics to prevent and treat infectious diseases and cancer.",Associate Professor,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/nc9a6c3ae
Julian,Leibowitz,Professor,We have two projects in my lab. The first project is focused on identifying evolutionarily conserved RNA secondary structures in the coronavirus RNA genome and functionally examining their role in viral replication through reverse genetic and biochemical approaches. We have previously done this for a number of RNA secondary structures contained within the 5? and 3? regions of the genome and shown that they function as cis-acting elements in replication. Studies in my laboratory have identified a structurally dynamic region of the 5'UTR that interacts with the 3'UTR to facilitate transcription.
A second project in my laboratory has been to develop a reverse genetic system for MHV-1. In collaboration with investigators in Toronto and Pennsylvania my laboratory has demonstrated that MHV-1 infection of susceptible mice provides a safe and convenient rodent model for severe coronavirus infections such as SARS and MERS. The development of a reverse genetic system will allow us to investigate the contributions of individual viral genes to the pathogenesis of the severe pulmonary disease caused by this virus.,Professor||Professor,Microbial Pathogenesis and Immunology||Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/ne2185aa0
Jeffrey,Cirillo,Professor,"Our laboratory is interested in the pathogenesis of bacterial lung infections particularly tuberculosis and Legionnaires' disease. We are examining the virulence mechanisms of bacteria using cellular, molecular and genetic techniques. Our primary research goal is to obtain a better understanding of the roles of the pathogen and host in disease. These studies should contribute to our understanding of host-pathogen interactions at the molecular and cellular level that can be used for prevention, treatment and diagnosis. We hope that through a better understanding of the mechanisms by which these organisms cause disease we can prevent some, if not all, of these infections in the future.",Professor||Director,Microbial Pathogenesis and Immunology||Center for Airborne Pathogen Research and Tuberculosis Imaging,https://scholars.library.tamu.edu/vivo/display/ne8bc1122