First name,Last name,Preferred title,Overview,Position,Department,Individual
Vishal,Gohil,Associate Professor,"Despite the fundamental role of the mitochondrion in cellular energy production and its involvement in numerous human diseases, we still do not know the function of nearly 20% of the known mitochondrial proteins. My laboratory applies genomic, genetic, and biochemical tools to uncover the role of these uncharacterized proteins in the mitochondrial respiratory chain (MRC) biogenesis. MRC is the main site of cellular respiration and energy production and since the core components of the MRC are evolutionarily conserved, we reason that the assembly factors required to build the MRC should also be conserved. Therefore, we utilize multiple models systems, including yeast, zebrafish, and human cell lines, to determine the role of these conserved, uncharacterized mitochondrial proteins in bioenergetics, organismal development, and human disease pathogenesis.
Another poorly understood aspect of the mitochondrial energy metabolism is the role of phospholipids in maintaining the structural and functional integrity of the MRC. Although it is well known that the MRC is localized in the inner mitochondrial membrane, how the unique lipid milieu of the mitochondrial membrane influences the assembly and activity of the MRC is not fully understood. We have constructed yeast mutants with defined mitochondrial phospholipid compositions to systematically determine each lipid's role in MRC assembly and activity. Ultimately, defining the roles of mitochondrial proteins and phospholipids will allow us to develop better diagnostic and therapeutic options for human disorders resulting from mitochondrial dysfunction.",Faculty Affiliate||Assistant Professor,Energy Institute||Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n03100e49
J.,Heatley,Associate Professor,,Associate Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/n0473e208
Hongwei,Zhao,Professor,,Professor,Epidemiology and Biostatistics,https://scholars.library.tamu.edu/vivo/display/n0698bd50
Hubert,Amrein,Professor,"My broad research interests are concerned with the sensory perception of the external chemical world. The central questions investigated in our laboratory are concerned with how animals detect and discriminate among the thousands of different chemical signals that ""flood"" the olfactory and taste organs. Our laboratory uses Drosophila as a model to study these problems because the Drosophilachemosensory systems are structurally and functionally very similar to those of mammals, yet they are smaller and somewhat less complex, which makes them excellent models to investigate the molecular and neural basis of olfaction and taste.",Senior Associate Dean of Research||Professor||Professor,Cell Biology and Genetics||School of Medicine||Nutrition,https://scholars.library.tamu.edu/vivo/display/n0839ec95
John,Edwards,Professor,,Professor,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/n09bbd732
Rajesh,Miranda,Professor,"My research is focused on fetal brain development, stem cells, microRNAs, and teratology. Our laboratory is interested in understanding the biological steps that transform uncommitted stem cells into neurons or a glial cells, and identifying key microRNAs that control the transformation of stem cells into neurons. We are also currently investigating what role teratogen-sensitive microRNAs play in fetal brain growth, and the spatial patterning of the emerging forebrain.",Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n0b271ea8
Kenita,Rogers,Executive Associate Dean,,Executive Associate Dean||Director for Diversity & Inclusion,School of Veterinary Medicine and Biomedical Sciences||School of Veterinary Medicine and Biomedical Sciences,https://scholars.library.tamu.edu/vivo/display/n0ced62b6
Iman,Borazjani,Associate Professor,"My research interests are in developing advanced computational tools for biofluids and fluid-structure interaction problems, which we employ to advance knowledge and gain insights into the physics of important biological/engineering flows.",Associate Professor,Mechanical Engineering,https://scholars.library.tamu.edu/vivo/display/n12f81112
Anil,Reddy,Adjunct Assistant Professor,,Adjunct Assistant Professor,Pediatric Dentistry,https://scholars.library.tamu.edu/vivo/display/n13b6796b
Guoyao,Wu,Distinguished Professor,"Dr. Wu teaches graduate courses in protein metabolism and nutritional biochemistry. He conducts research in protein and amino acid metabolism at molecular, cellular, and whole body levels . The animal models used in his research include cattle, chicks, pigs, rats, sheep, fish, and shrimp. He has also conducted research on amino acid nutrition in humans.",Faculty Fellow||University Faculty Fellow||Distinguished Professor||Senior Faculty Fellow||Distinguished Professor,Veterinary Integrative Biosciences||Animal Science||Texas A&M AgriLife Research||Texas A&M AgriLife Research||Nutrition,https://scholars.library.tamu.edu/vivo/display/n169f9a74
Ping,Xiang,Professor,,Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/n1d2223c8
Xiuren,Zhang,Professor,"Our laboratory focuses on systemic analysis of biochemical, molecular and biological functions of AGO family proteins (AGOs-mics) in genetically tractable Arabidopsis and economically important crops (i.e. rice). We'd like to identify the small RNAs, mRNA targets and protein components which associate with these AGOs. We will study protein/RNA and protein/protein interactions in these RISC assembly events. Our goal is to understand how these AGOs are functionally specialized or redundant corresponding to endogenous development cues and external environmental stimuli. Particularly, we'd like to learn how plants reprogram their gene expression through the small RNAs and AGOs to construct a new cellular niche in responses to environmental challenges and biotic stresses.
Another aspect of our research involves host/virus interaction. Plants take advantage of RNA silencing pathways to defend themselves from exogenous nucleic acid invaders (i.e. viruses). As an anti-host defense mechanism, viruses encode suppressors that can block RNA silencing responses. We have recently demonstrated that CMV 2b disables AGO1 cleavage activity to inhibit RNA silencing and to counter host defense. We are now extending our study to suppressors of several other viruses and the molecular mechanisms of their suppression.",Associate Professor,Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n220933ad
Satish,Bukkapatnam,Professor,"Dr. Bukkapatnam's research addresses the harnessing of high-resolution nonlinear dynamic information, particularly from wireless MEMS sensors, to improve the monitoring and prognostics of real-world systems, including ultraprecision and nanomanufacturing processes and machines, and cardiorespiratory processes. His research has led to 185 peer-reviewed publications (115 published/ accepted in journals and 70 in conference proceedings), 1 granted and five pending patents, and has been the basis for 17 Ph.D. dissertations. His research has received support from federal agencies including National Science Foundation, Department of Energy, and Department of Defense, and the private sector including General Motors, Ford, National Instruments, and the Central Rural Electric Cooperative.",Faculty Affiliate||Professor,Energy Institute||Industrial and Systems Engineering,https://scholars.library.tamu.edu/vivo/display/n277d780c
Mariappan,Muthuchamy,Professor,"The main goal of our laboratory is to understand the molecular mechanisms of cardiac muscle dynamics in normal and diseased states. Particularly, our interests focus on the relationships between thin filament activation and crossbridge kinetics, and how the mechanotransduction signaling transmits to myofilament activation. We use multiple techniques, molecular, cellular, biochemistry, structural and biophysical, to obtain information on the fundamental regulatory mechanisms of cardiac muscle contraction.
Our lab group is also investigating the role of lymphatics in different tissue beds, including mesentery, skeletal muscle, and brain using various animal models.",Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/n2877399b
Lene,Petersen,Instructional Assistant Professor,"The main research focus of my lab is to understand how environmental (temperature, hypoxia, salinity) and anthropogenic (pharmaceuticals, contaminants) stressors affect animal physiology. In particular, we are interested in understanding cardiovascular, respiratory, reproductive and metabolic responses to stressors. We study effects of short (few hours/days) and long-term (weeks) stressors (individual or multiple) at all levels of biological organization (molecular, cellular, organ and whole-organism), and developmental stages (early life stage to adult). Understanding how perturbations in the animal's environment mechanistically affect survival is important in assisting conservation efforts. We are currently studying physiological responses in American alligators and local Gulf of Mexico fish species.",Instructional Assistant Professor,Marine Biology,https://scholars.library.tamu.edu/vivo/display/n2a4c4096
Xiaoning,Qian,Associate Professor,"Xiaoning Qian's research interests include machine learning and Bayesian experimental design as well as their applications in computational network biology, genomic signal processing, and biomedical signal and image analysis. He is affiliated with the Center for Bioinformatics and Genomic Systems Engineering and the Center for Translational Environmental Health Research at Texas A&M.",Associate Professor,Electrical and Computer Engineering,https://scholars.library.tamu.edu/vivo/display/n2c8e24e9
Shaodong,Guo,Professor and Presidential Impact Fellow,"The long-term goal of our research is to study the molecular mechanisms of insulin signal transduction, insulin resistance and associated cardiovascular dysfunction, aiming at nutritional and therapeutic intervention for control of metabolic and cardiovascular disorders. My laboratory is focused on the study of cellular signaling and gene transcriptional regulation of metabolic homeostasis that are governed by the PI3K->Akt->FoxO pathway, with the hope of understanding how dysregulation of this pathway in insulin/IGF-1 action causes liver damage, cardiovascular dysfunction, and pancreatic beta cell failure, resulting in diabetes, obesity, and organ failure.",Professor,Nutrition,https://scholars.library.tamu.edu/vivo/display/n2ef8f395
Bradley,Simon,Clinical Assistant Professor,,Clinical Assistant Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/n30b14599
Aaron,Morton,Assistant Professor,"My research focus centers around soft tissue regeneration and applied biomaterial applications. In particular, I have focused on a novel class of biocompatible ceramics, suitable for soft tissue implantation. To complement this work, I investigate Schwann cell and blood vessel interaction during regeneration and evaluate mitochondrial morphology through high-resolution imaging. My lab primarily uses murine models and is uniquely skilled at assisting rodent muscle function.",Assistant Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/n312f7efe
Randolph,Stewart,Clinical Professor,cardiovascular physiology; lymphatic function; microvascular physiology; interstitial and cavity fluid balance,Clinical Professor,Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/n332dadae
John,Criscione,Professor,,Professor,Biomedical Engineering,https://scholars.library.tamu.edu/vivo/display/n33d294c3
Jim,Ji,Professor,"Technological advances in magnetic resonance imaging (MRI) and magnetic resonance spectroscopic imaging (MRSI) provide unprecedented opportunities for revealing the anatomical, pathological, and functional information of biological systems and improving our understanding of the biological processes. During the last two decades, MR hardware and sequence design have been significantly improved, which make MRI and MRSI faster and finer than they have ever been. However, dynamic imaging of 3D objects, a beating heart or a working brain, for examples, is still a big challenge.
The research in our group is to develop 3-D, real-time imaging capability to visualize biological events as they are happening, and advanced analysis techniques to extract the desired information from biological images automatically, accurately and consistently.",Professor||Professor,Electrical and Computer Engineering (Qatar)||Electrical and Computer Engineering,https://scholars.library.tamu.edu/vivo/display/n35d3773d
Everett,Bailey,Professor,,Professor,Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/n3659b74a
Keila,Ida,Clinical Assistant Professor,,Clinical Assistant Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/n36ce5081
Bradley,Weeks,Professor Emeritus,"Retired Professor, Veterinary Pathobiology Department. Collaborator as ACVP board-certified anatomic pathologist in research projects that include implanted medical devices inflammatory and neoplastic gastrointestinal diseases, and cardiovascular diseases.",Professor Emeritus,School of Veterinary Medicine and Biomedical Sciences,https://scholars.library.tamu.edu/vivo/display/n3d42a32c
Ryang,Lee,Associate Professor,"Our group specializes in determining the cellular and molecular mechanisms of beneficial effects of mesenchymal stem cells (MSCs) in diseases that include heart disease, diabetes, and peritonitis. The goal is to develop a cellular therapy for human diseases either (a) with adult stem/progenitor cells (MSCs), or (b) with therapeutic factors that MSCs produce in response to signals from injured tissues.",Associate Professor,Cell Biology and Genetics,https://scholars.library.tamu.edu/vivo/display/n3ffcdcc1
Travis,Hein,Professor,"My laboratory studies the regulation of microvascular function at the level of arterioles in the retinal and coronary circulations. Sufficient blood flow supply of oxygen and nutrients to tissues to maintain normal function is controlled in large part by changes in the diameter of arterioles. Vasoconstriction or vasodilation of these small arteries will decrease or increase blood flow and nutrient delivery to the tissue, respectively. Two key chemical factors that are produced within the endothelial cells of blood vessels to control their diameter are nitric oxide (NO), a vasodilator, and endothelin-1, a vasoconstrictor. An imbalance in the production and/or release of these vasoactive factors has been implicated in the early stages of several cardiovascular diseases, but the underlying mechanisms contributing to these pathophysiological changes remain unclear. To address this knowledge gap, our research focuses on identifying cellular and molecular mechanisms that contribute to the vasomotor responses of arterioles to NO and endothelin-1 under conditions of health and disease. Current approaches that we use to investigate these mechanisms in the microcirculation include isolated and perfused arterioles, cultured vascular endothelial and smooth muscle cells, biochemical and molecular techniques (for detection of NO, superoxide anion, protein, and mRNA in arterioles), pharmacological and silencing RNA (siRNA) treatments, and blood flow velocity assessment via Doppler ultrasound.",Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/n45051e1b
Sonya,Wesselowski,Assistant Professor,,Assistant Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/n45e117fa
Kenneth,Ramos,Professor and Executive Director,,Professor of Medicine||Professor and Executive Director||Executive Committee||Associate Vice President for Research||Assistant Vice Chancellor for Health Services,The Texas A&M University System||Institute of Biosciences and Technology||Global Institute for Hispanic Health||School of Medicine||Health Science Center,https://scholars.library.tamu.edu/vivo/display/n47de353a
Louisbruno,Ruest,Associate Professor,,Associate Professor,Biomedical Sciences,https://scholars.library.tamu.edu/vivo/display/n4ba9bf37
Candice,Brinkmeyer-Langford,Research Associate Professor,"My research focuses on the roles of genetic diversity on neurological conditions resulting from environmental agents, such as viral infections. We use Theiler's Murine Encephalomyelitis virus (TMEV), a neurotropic virus affecting mice, and the genetically diverse Collaborative Cross mouse resource, to study the mechanisms underlying neuropathological outcomes to infection.",Research Associate Professor,Veterinary Integrative Biosciences,https://scholars.library.tamu.edu/vivo/display/n55d547f4
Glen,Laine,Regents Professor,,"Director , Michael E BeBakey Institute||Professor",Michael E. DeBakey Institute||Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/n58440639
Linglin,Xie,Associate Professor,,Assistant Professor,Nutrition,https://scholars.library.tamu.edu/vivo/display/n5aa6a1af
Sonya,Gordon,Professor,,Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/n5ac1c075
Vinayak,Krishnamurthy,Assistant Professor,"I work at the interface of three disciplines: geometric modeling, human-computer interactions and design research. Broadly, I am interested in investigating the role of mixed-initiative interactions for augmenting human expression and creativity in product, industrial and engineering design. The central objective of my research is to enable expression of design intent for idea generation during early phase conceptual design. To this end, my work involves development of new techniques in computer-aided design (CAD), geometry & image processing, information visualization for conceptual design, mobile & wearable interfaces for creativity support, computer-aided ergonomics, and AR/VR (augmented and virtual reality) interfaces for design.",Assistant Professor,Mechanical Engineering,https://scholars.library.tamu.edu/vivo/display/n5c749413
Gladys,Ko,Professor,,Professor,Veterinary Integrative Biosciences,https://scholars.library.tamu.edu/vivo/display/n5e930c1f
Fred,Clubb,Clinical Professor,"Providing innovative, objective pathology support of the utmost quality to improve medical device technologies and subsequently, patients' lives and creating learning opportunities and new knowledge for students and the scientific community.",Clinical Professor,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/n62494da9
Jon,Skare,Regents Professor and Associate Head,"Jon Skare is Regents Professor and Associate Head of the Department of Microbial Pathogenesis and Immunology in the College of Medicine at Texas A&M University. He has been a faculty member at Texas A&M since 1996 and has led a research laboratory centered around the pathogenic mechanisms operative in Borrelia burgdorferi, the spirochetal bacterium that causes Lyme disease. He has published over 50 peer reviewed manuscript, reviews, and book chapters and been funded continuously by the NIH since 1999 with over $20 million dollars in total costs. Dr. Skare has trained ten graduate students, sixteen postdoctoral fellows, and numerous undergraduate students in his research group during his time at Texas A&M. The majority of his postdoctoral trainees and students have gone on to hold academic or industry positions in the medical sciences.
Research interests are focused on microbial pathogenesis with an emphasis in spirochetal infections, particularly Borrelia burgdorferi, the etiologic agent of Lyme disease. Broad training in the molecular biology, genetics, and biochemistry of prokaryotic systems is employed to answer research-related questions. Long-term interests in the lab are centered on understanding how B. burgdorferi promotes its pathogenic potential and persists in the disparate hosts it occupies in nature (e.g., both ticks and mammals). In this regard, the research program is aligned with: (i) regulatory pathways that contribute to the establishment of infection during the arthropod to mammalian transition; (ii) identifying and characterizing surface structures that contribute to the colonization and maintenance of infection via adherence mechanisms; and (iii) the ability of B. burgdorferi and relapsing fever Borrelia to persistently infect hosts in the face of a potent innate and adaptive immune response.",Professor and Associate Head,Microbial Pathogenesis and Immunology,https://scholars.library.tamu.edu/vivo/display/n638ae603
Adam,Case,Associate Professor,"Redox signaling is vital for proper immune system function, yet this area of research is understudied. My graduate career focused on the role of mitochondrial superoxide in T-lymphocyte development. I transitioned this expertise into my postdoctoral training where I examined the role of redox signaling in T-lymphocytes during the pathogenesis of cardiovascular disease. As an independent investigator, I have extended this work to identify the contribution of the immune system and redox signaling to different pathological states of psychological trauma and stress. With this, I am investigating the redox, metabolic, and epigenetic mechanisms that may affect immune cell function and potentiate psychological trauma-mediated inflammatory diseases.",Associate Professor||Associate Professor,Medical Physiology||Psychiatry and Behavioral Sciences,https://scholars.library.tamu.edu/vivo/display/n63d8248e
David,Earnest,Professor,"Research in my laboratory employs multidisciplinary approaches to study the cellular and molecular neurobiology of cell-autonomous circadian clocks and the signal transduction pathway responsible for circadian photoentrainment. The aims of current projects are to study: 1) the role of microRNAs (miRNAs) and other signaling molecules in the local temporal coordination of cell- and tissue-specific circadian clocks; 2) mutual interactions between the circadian clock mechanism, inflammatory signaling and metabolism; and 3) the mechanisms linking circadian rhythm disruption with metabolic disorders such as obesity and diabetes, and with pathological changes in neuroprotective responses to stroke.",Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/n640c528f
Mary,Mcdougall,Associate Professor,,Associate Professor,Biomedical Engineering,https://scholars.library.tamu.edu/vivo/display/n64af6396
Fatemehsadat,Tabei,TEES Researcher at West TAMU,,Assistant Professor||TEES Researcher at West TAMU,"TEES Regional Divisions||West Texas A&M University - (Canyon, Texas, United States)",https://scholars.library.tamu.edu/vivo/display/n69c14673
John,Lawler,Professor,,Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/n69cbc828
Ann,Kier,Professor Emerita,,Professor,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/n6c0ad160
Ling,Yu,Research Associate Professor,,Research Associate Professor,Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/n6fbf4093
Margaret,Glasner,Associate Professor,"Evolution is the organizing principle of biology and provides the cornerstone of our approach to understand the relationships between protein structure and function. We combine bioinformatics, biochemistry, and genetics to address fundamental questions about protein evolution, such as: What structural and mechanistic features of enzymes increase their capacity to evolve new functions? How do new metabolic pathways evolve? Are there multiple evolutionary pathways to evolve new enzyme activities?
Our primary focus is on how catalytic promiscuity serves as the raw material for evolving new enzyme activities. Catalytic promiscuity is the ability to catalyze different chemical reactions using the same active site. Many enzymes in one branch of the protein family we are studying are catalytically promiscuous, and this activity has been incorporated into new metabolic pathways more than once. Comparing the sequences and structures of these proteins will identify characteristics that permitted them to evolve the second activity.
Our goal is to use results from our research to identify fundamental evolutionary principles that can can help decipher protein structure-function relationships, predict protein functions, and improve protein engineering methods.",Associate Professor,Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n721200c3
Xu,Peng,Associate Professor,"Our long-term goal is to explore and define novel genetic mechanisms that are involved in cardiovascular disease which can ultimately translate into potential strategies for its treatment. To achieve this goal, we will use a comprehensive approach including mouse genetics and molecular and cellular biology methods to explore the mechanisms involved in the regulation of cardiovascular development and disease.",Associate Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/n78b50f7c
Charles,Johnson,"Director, Genomics and Bioinformatics Service","Agrigenomics and bioinformatics research and technology development. Research focusing on high throughput next generation sequencing technologies and its application in agriculture. Building an ever growing collaborative network of spanning 62 departments across Texas A&M system, and a rapidly growing list of international collaborators ( 45 countries) and industrial partners. Founding Executive Director of the Center for Bioinformatics and Genomic Systems Engineering (CBGSE).",Director Institute,Texas A&M AgriLife Research,https://scholars.library.tamu.edu/vivo/display/n79e93fe9
Michael,Moreno,Director of Innovation for Engineering Medicine,"Dr. Moreno is the J. Mike Walker '66 Faculty Fellow in the Department of Mechanical Engineering, and serves as Director of Innovation for Engineering Medicine (EnMed). In addition, he has joint appointments in the Departments of Biomedical Engineering, Small Animal Clinical Sciences, Health and Kinesiology, and Medical Education at Texas A&M University. Dr. Moreno has over 20 years of experience developing enabling technologies in the fields of experimental biomechanics and medical research across multiple scales including cell, tissue, organ, and whole-body systems. His work has culminated in the development of therapeutic medical technologies and testing systems for medical technologies, including implantable medical devices and tissue engineered regenerative therapies. He currently holds 8 patents and an active provisional patent related to COVID technologies. He is director of the Biomechanical Environments Laboratory, which operates in accordance with the Food and Drug Administration (FDA) Quality System Regulation (QSR). He has designed custom mechanical testing systems and protocols for FDA Good Laboratory Practices (GLP) preclinical mechanical testing and animal safety studies. In addition, Dr. Moreno is a co-founder of Biomechanics Innovation Group (BIG) LLC and has worked previously as a consultant in developing experimental flow and mechanical testing systems and protocols for several major medical device companies (e.g. Boston Scientific, Medtronic, Cordis, Flowmedica, etc.). Dr. Moreno was the recipient of the 2016 Dean of Engineering Excellence Award and 2016 TEES Young Faculty Fellow Award. He was a 2012 recipient of the American Society of Mechanical Engineers Skalak Award for best paper. He is a recipient of the Student Led Award for Teaching Excellence (SLATE Award) and the Senator Phil Gramm Award for Excellence in Scholarly Research and Teaching. He has developed and taught courses in Medical Device Design, Bio-Inspired Engineering Design, Biofluid Mechanics, Biosolid Mechanics, Orthopedic Biomechanics, Motion Biomechanics, and Comparative Biomechanics. As a key curriculum developer for the new Engineering Medicine (EnMed) Program, he developed the Introduction to Engineering Innovation in Medicine, Innovation Immersion Experiences, and the Innovation in Clerkships courses. As Director of the Engineering World Health Summer Institute in Rwanda, an immersive service-learning study abroad program, he teaches Healthcare Technology in the Developing World. He is an active member of the American Society of Mechanical Engineers and currently serves as Chair of the Design, Dynamics, and Rehabilitation Committee. He is also a member of the Biomedical Engineering Society and the European Society of Biomechanics. Dr. Moreno is co-author of 40 peer-reviewed journal publications and 7 book chapters. He has received funding from the National Institutes of Health, National Science Foundation, Department of Defense, and Industry sponsors.",Associate Professor,Mechanical Engineering,https://scholars.library.tamu.edu/vivo/display/n7b729e4b
Stephen,Crouse,Professor,"My research focus is in the general area of Exercise as Medicine. My specific health-related research aims have been targeted toward the study of the effects of exercise on blood lipid metabolism, and on other accepted heart and cardiovascular disease risk factors in men and women, young and old. Current research in exercise physiology is focused on the adaptive response of the cardiovascular and musculoskeletal system to exercise, nutrition, and physical training using aquatic, endurance, and resistance modalities of exercise. In progress are research projects in sports physiology to profile elite athletes and study factors that contribute to the health of athletes, including nutritional supplements.",Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/n7e212aee
J Timothy,Lightfoot,Professor,"My research focuses on on the genetics of daily physical activity and exercise endurance, as well as the physiological response to high-G exposure and hemorrhage, and the genetics of physical activity. My lab also has a unique interest in the physiological responses of athletes in a variety of non-traditional venues such as auto racing and in musicians.",Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/n7ec5bc99
Peter,Davies,Professor,,Interim Department Head||Professor and Director,Center for Translational Cancer Research||Translational Medical Sciences,https://scholars.library.tamu.edu/vivo/display/n83f40a4a
Kamlesh,Yadav,Instructional Associate Professor,"Dr. Yadav's primary interest is in translational research, specifically biomarker discoveries and novel therapeutics in cancer (especially prostate) through a combination of biochemistry and genomics. He is also interested in mining EMRs for personalized diagnosis, prognosis and therapeutics using real worlds evidence (RWE) data coupled with machine-learning/AI-algorithms.",Instructional Associate Professor,School of Medicine,https://scholars.library.tamu.edu/vivo/display/n855387b4
Rosemary,Walzem,Professor,"Dr. Walzem's core research focus within the laboratory is directed towards understanding how the structure of triglyceride-rich lipoproteins influences their ability to carry out specific nutrient delivery tasks. Her studies include identification of mechanisms and regulatory processes that control the assembly of trigylceride-rich lipoproteins in issues, structural studies of lipoproteins themselves and physiological studies to determine substrate properties and metabolic fates of different types of lipoproteins. Diet can significantly alter lipoprotein physiology through multiple mechanisms, and studies of diet effects provides a significant sub-theme to the research program. A variety of species are used to address specific questions, however, avian and human lipoprotein metabolism as it relates to egg production and atherogenesis, respectively, are emphasized.",Professor,Poultry Science,https://scholars.library.tamu.edu/vivo/display/n85cd191f
Alex,Keene,Professor and Department Head,,Professor and Department Head,Biology,https://scholars.library.tamu.edu/vivo/display/n8650c3cf
Mariana,Janini Gomes,Assistant Professor,,Assistant Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/n8e75a22c
David,Threadgill,Professor,"Our laboratory uses the mouse as an experimental genetic model to investigate factors that contribute to inter-individual differences in health and disease. Ourcurrent research activities include the identification and functional characterization of alleles contributing to cancer susceptibility, the function of theErbbgenefamily in development and disease, and the role of genetic variation in response to environmental stimuli. To support these investigations, we also aredeveloping new genetic tools to support mammalian systems genetic approaches to phenotypes with complex genetic and environmental etiologies.",Director||Professor||Professor||Professor,Cell Biology and Genetics||Institute of Genome Sciences and Society||Biochemistry and Biophysics||Nutrition,https://scholars.library.tamu.edu/vivo/display/n8ee0b54f
Mary,Meagher,Professor,,"Professor||Faculty Fellow||Claude H. Everett, Jr. ’47 Chair of Liberal Arts||Professor",Center for Health Systems and Design||Texas A&M Institute for Neuroscience,https://scholars.library.tamu.edu/vivo/display/n8fa87422
James,Sacchettini,Professor,"My lab uses X-ray crystallography to better understand the relationship between proteins and ligands. Tiny differences in the structure of a molecule can radically change the interaction between a protein and ligand and we are only begining to understand how many factors play a role in this interaction. By manipulating the individual components of a compound it is possible to create a chemical that binds to the protein better than the natural substrate, and prevent the natural reaction from occurring. This is the basis for rational drug design. Our efforts have lead us to collaborations with other labs and scientists in many disciplines as our approach to directed compound design has applications not only in basic research but also in pesticide development, health research and clinical research.",Professor,Biochemistry and Biophysics,https://scholars.library.tamu.edu/vivo/display/n90385563
Marielle,Engelen,Professor,"My research focuses on the metabolic alterations underlying involuntary weight loss and muscle wasting in chronic inflammatory diseases, involving the use of stable isotope methodologies, and the effects of dietary modulation and exercise intervention to restore metabolism and physical performance in these patients.",Professor||Professor,Kinesiology and Sport Management||Center for Translational Research in Aging and Longevity,https://scholars.library.tamu.edu/vivo/display/n90a05e0d
Erma,Eades,Professor and Head,,Professor and Head,Large Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/n9271bd37
Timothy,Phillips,Professor,food safety; molecular toxicology; elucidation of fundamental chemical mechanisms of toxic action/interaction of food-borne carcinogens; mutagens; and developmental toxicants; and development of methods to detect and detoxify foodborne and environmental toxins.,Professor,Veterinary Integrative Biosciences,https://scholars.library.tamu.edu/vivo/display/n94eef946
Thomas,Peterson,Instructional Professor,,Instructional Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/n95a0c035
Shenyuan,Zhang,Associate Professor,,Associate Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/n95b01f7e
Ahmed,Abdel-Wahab,Professor,"Dr. Abdel-Wahab's primary focus is on chemical, electrochemical, and physical processes associated with treatment of water and wastewater, carbon dioxide conversion, and green hydrogen production from water splitting. This research has attracted significant external funding totaling more than $12M as the lead principal investigator and more than $6M as co-investigator. Abdel-Wahab's research has led to publication of more than 130 peer-reviewed articles in leading research journals, 9 book chapters, and more than 80 refereed conference publications/presentations. He is an editorial board member of the Journal of Water Process Engineering (Elsevier) and an associate editor of Emergent Materials Journal (Springer).","Technical Director, QWE||Faculty Affiliate||Professor||Professor",Civil Engineering||Texas A&M University at Qatar||Energy Institute||Chemical Engineering (Qatar),https://scholars.library.tamu.edu/vivo/display/n96a2a261
Fei,Liu,Associate Professor,"Our laboratory conducts research in:
1. The characterization and application of standardized mesenchymal stem cells (MSCs) derived from iPS cells and their extracellular vesicles (EVs). Current application focuses on treating diseases caused by over-activation of immune system, such as Sjogren's syndrome, an autoimmune disease causing dry eyes and dry mouth, and cytokine storm caused by infections.
2. Roles of tissue-resident macrophages in the development, homeostasis, and regeneration of salivary glands damaged by radiation therapy for cancer.",Associate Professor,Cell Biology and Genetics,https://scholars.library.tamu.edu/vivo/display/n9732f08e
Vincent,VanBuren,Assistant Professor,,Instructional Assistant Professor,School of Medicine,https://scholars.library.tamu.edu/vivo/display/n98068f16
Ke,Zhang,Associate Professor,"Dr. Zhang's long-term goal is to decode genetic events and molecular interactions of biological processes, and rigorously represent the complex molecular behaviors with mathematical models. We use advanced high-throughput technology and robust stochastic models to obtain the systematic picture of a biological process. Multiple types of omics data, such as microarray, RNA-seq, ChIP-seq, lipidomics and proteomics are collected through innovative study designs in animals and humans, and are modeled for integrative analysis. Using embryonic mouse as a model system, one of our current focuses is to untangle the spatial and dynamic gene-gene interaction networks during heart development, and illustrate how environmental factors introduce adverse molecular changes and morphological defects. We are also investigating the transgenerational epigenetic variations carried from overweight mother to the offspring, and how the change of lifestyles would prevent childhood obesity.",Associate Professor||Associate Professor,Institute of Biosciences and Technology||Nutrition,https://scholars.library.tamu.edu/vivo/display/n9d8b0bca
Masako,Suzuki,Assistant Professor,,Assistant Professor,Nutrition,https://scholars.library.tamu.edu/vivo/display/n9fd0c6a8
Chaodong,Wu,Professor and Presidential Impact Fellow,"The long-term goal of Dr. Wu's research program is to elucidate the mechanisms underlying the pathogenesis of obesity and overnutrition-associated metabolic diseases including insulin resistance, diabetes, and fatty liver disease so that novel dietary and/or pharmacological approaches can be developed for preventing and/or treating metabolic diseases. Using molecular, cellular, and integrative approaches, the Wu lab is focused on investigating the interaction between metabolism and inflammation.",Professor||Professor,Texas A&M AgriLife Research||Nutrition,https://scholars.library.tamu.edu/vivo/display/na24a9d43
Marlan,Scully,Distinguished Professor,,Distinguished Professor||Faculty Affiliate,Physics and Astronomy||Energy Institute,https://scholars.library.tamu.edu/vivo/display/na2a37577
Jeremy,Wasser,Associate Professor,,Associate Professor,Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/na2c152a7
Xin,Wu,Research Assistant Professor,"Mechanical forces are known to stimulate a number of cell signaling pathways, including those initiated by or resulting in ion channel activation. My recent research in cardiovascular and neuronal systems focuses on: (1) Which ion channels are activated by mechanical stress; (2) Which ion channels are modulated by integrins; (3) How integrin-mediated signaling pathways modulate ion channel function and mechanotransduction in physiological and pathological conditions; (4) Epilepsy study, Neurosteroids and New Drug Development.",Research Assistant Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/na48dc2f9
Saurabh,Biswas,"Executive Director, Technology Transition & Professor of Practice",,"Executive Director, Commercialization & Entrepreneurship||Associate Professor of Practice, Biomedical Engineering",Texas A&M Engineering Experiment Station (TEES)||Biomedical Engineering,https://scholars.library.tamu.edu/vivo/display/na7af81ca
Jerome,Trzeciakowski,Professor and Associate Department Head,,Professor and Associate Department Head,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/na90a7aab
Samba,Reddy,Professor,"My major research goals are to understand the molecular pathophysiology and develop novel therapeutic strategies for epilepsy, with an emphasis on neurosteroids and GABA inhibition in the brain. Neurosteroids are steroids synthesized locally within the brain that rapidly change neural excitability by non-genomic mechanisms, principally via postsynaptic GABAA receptors that play critical role in epilepsy. Current work in his lab is focused on uncovering molecular mechanisms of neurosteroids in epilepsy and brain disorders, and testing the efficacy of mechanism-based, rationale therapeutic strategies for epilepsy and epileptogenesis. Reddy lab is utilizing multidisciplinary approaches such as pharmacological, molecular, electrophysiological (patch-clamp), mass spectrometry, and transgenic mouse models in research projects.",Professor,Neuroscience and Experimental Therapeutics,https://scholars.library.tamu.edu/vivo/display/na96b32aa
Karen,Snowden,Professor and Associate Department Head,"Parasites of public health importance, host-parasite interactions, development of animal models for the study of parasitologic diseases and treatments, and development of molecular and immunologic methods for parasitologic diagnosis.",Professor and Associate Department Head,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/naab1ec85
David,Zawieja,Regents Professor and Department Head,"My lab has had a number of research projects focusing on the study of lymphatic structure and function. Each of these projects has, as one of their objectives, the evaluation of the mechanisms (molecular, cellular, mechanical and tissue-level) regulating different aspects of lymphatic function. These projects focus on the ionic/calcium, contractile/regulatory proteins, molecular pathways that regulate lymph transport, lymphatic muscle function, the role of lymphatic function in the generation and resolution of tissue inflammation and the interactions between immune cells and the lymphatic cells. To support this work we have established cultured cell lines of both endothelial and muscle isolated from microlymphatics, acute and cultured isolated microlymphatic tissues, methodologies to evaluate lymphatic function at the single vessel, whole tissue and animal levels, methodologies to target cell-specific gene manipulation in isolated lymphatic tissues, approaches to microscopically image and model lymphatic network structure and function in 3D in lab animals. We have also evaluated the effects of space flight, various inflammatory mediators and other immune activation processes on lymphatic contractile and transport function and how these affect immunity. Finally, we have evaluated different types of lymphatic pathology resulting in lymphedema, various inflammatory diseases and immune dysfunction.",Regents Professor and Head||Professor and Associate Department Head,The Texas A&M University System||Medical Physiology,https://scholars.library.tamu.edu/vivo/display/nad1e71e4
Ian,Tizard,Dr.,"Immunology with an emphasis on innovative vaccine technology and on the immunology of domestic mammals.Avian diseases with an emphasis on diseases of psittacines, Paleovirology,Genomics with an emphasis on whole avian genomes.The intestinal microbiome and its role in immunity.",University Distinguished Professor,School of Veterinary Medicine and Biomedical Sciences,https://scholars.library.tamu.edu/vivo/display/naefbabcf
Srinath,Palakurthi,Professor,,Professor,Pharmacy Practice,https://scholars.library.tamu.edu/vivo/display/nafb53cb2
Brandon,Schmeichel,Professor,"I have broad interests in social and personality psychology, particularly the human capacity for self-control. My research examines willpower, choice, memory, motivation, emotion, and emotion regulation.",Professor,,https://scholars.library.tamu.edu/vivo/display/nb08afaf3
Reza,Avazmohammadi,Assistant Professor,,Assistant Professor,Biomedical Engineering,https://scholars.library.tamu.edu/vivo/display/nb090186f
Katie,Tolbert,Clinical Associate Professor,"Dr. Tolbert's clinical research program is focused on small animal gastroenterology with a specific interest in the investigation of the efficacy of anti-secretory drugs and gastroprotectants and the rationale for their use in the treatment of acid-related disorders, organ failure, and inflammatory diseases in companion animals. Her basic science research program is dedicated to characterizing the pathogenic mechanisms of feline Tritrichomonas foetus infection and exploring novel therapies to prevent and/or ameliorate T. foetus-induced colitis.",Clinical Associate Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/nb2572e7b
Paula,Giaretta,Clinical Assistant Professor,,Clinical Assistant Professor,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/nb54d37da
Jyhwen,Wang,Professor,"My areas of current research include:
manufacturing of micro-scale surface features, energy-efficient metal cladding process, plastic deformation
of coated materials, design and analysis of advanced honeycomb and porous structures, hydroforming of
sandwich panels, and prediction of sheet metal formability.",Professor||Faculty Affiliate,Engineering Technology and Industrial Distribution||Energy Institute,https://scholars.library.tamu.edu/vivo/display/nb656e254
Warren,Zimmer,Scott Exter Professor,"Our research interests are directed towards understanding the complex mechanisms which regulate the expression of specific gene sequences in development. We have focused our studies upon the factors that influence the smooth muscle component of the developing gastrointestinal (G.I.) tract. It has been shown that smooth muscle cells are predominantly derived from mesodermal precursor cells, however the factors regulating the selection of the smooth muscle myogenic pathway is not well defined.",Scott Exter Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/nb6da0749
Christabel Jane,Welsh,Professor,Mechanisms of disease pathogenesis of neurotropic viruses. Immunological therapies for multiple sclerosis and epilepsy. Neuroimmunological changes in the injured CNS,Professor,Veterinary Integrative Biosciences,https://scholars.library.tamu.edu/vivo/display/nbb081247
Lih,Kuo,Regents Professor,"My research focuses on the physiological and pathophysiological regulation of coronary and retinal microcirculation. In the circulatory system, the amount of blood delivered to each tissue can be regulated by the activity of arterial microvessels (<100 m in diameter). Changes in vascular tone, i.e., constriction or dilation of these microvessels, will decrease or increase blood supply to the tissue, respectively. However, the mechanisms involved in the regulation of vascular tone are not completely understood. Our current research focuses on the regulation of microvascular tone by hemodynamic (e.g., pressure and shear stress), metabolic (e.g., adenosine, osmolarity, K+, pH, pO2) and neural (adrenergic receptors) factors. To have an integrative view on the flow regulation, this basic information are reconstructed using mathematical model and computer simulation technology. This research provides a basic foundation critical to our understanding of blood flow regulation in the microvascular network under normal and disease states.",Regents Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/nbc742025
Richard,Kreider,Professor,"Director of the Exercise and Sport Nutrition Lab.
We study the role of exercise and nutrition on health, performance, disease and rehabilitation.","Faculty Fellow||Professor and Head||Director||DIrector, Human Clinical Core||Professor",Center for Health Systems and Design||Kinesiology and Sport Management||School of Education and Human Development||The Exercise and Sport Nutrition Laboratory||Nutrition,https://scholars.library.tamu.edu/vivo/display/nbc81b4e0
Nicolaas,Deutz,Professor,"My research background and expertise focus on nutrition, metabolism, and physiology studies involving the use of stable isotope methodologies, both in humans and animals. I also have extensive experience with isotopic calculations, validation and data interpretation.",Professor,Primary Care and Rural Medicine,https://scholars.library.tamu.edu/vivo/display/nbd596655
Sai,Koka,Associate Professor,"My research is focused on the studying the cellular and molecular mechanisms regulating the development of cardiometabolic disorders and identifying novel pharmacologic strategies to combat cardiovascular cardiovascular diseases such as atherosclerosis, endothelial and vascular dysfunction in diabetic, obese and aging patients. Currently we are exploring the role of gut microbe-derived metabolites in endothelial and vascular cell signaling.",Associate Professor,Pharmaceutical Sciences,https://scholars.library.tamu.edu/vivo/display/nbdc012b7
Carl,Tong,Associate Professor,"Cardiovascular disease remains as the number one cause of mortality. About 50% of heart failure patients will perish in five years. At age 40, lifetime risk of developing heart failure is one in five. Diastolic dysfunction heart failure prevalence has increased to 50% of all heart failure. In this context, My research is dedicated to elucidating underlying mechanisms and translating discoveries to new treatments.",Associate Professor,Medical Physiology,https://scholars.library.tamu.edu/vivo/display/nbf050ef5
Peter,Nghiem,Associate Professor,"Molecular, cellular, and phenotypic characterization of the canine models for Duchenne muscular dystrophy (golden retriever muscular dystrophy [GRMD]; german short-haired pointer muscular dystrophy [GSHPMD]; cavalier king charles spaniel muscular dystrophy). Molecular characterization with genome-wide mRNA and microRNA profiling via Affymetrix chip and proteomic profiling with mass spectrometry. Confirmation of molecular targets with qRT-PCR, western blot, immunofluorescence microscopy, etc. Cellular characterization of the canine models utilizing biopsy extracted muscle stem cells (myoblasts), including evaluation of the molecular and phenotypic effects of various treatments. Phenotypic characterization of the canine models using internationally established functional outcome measures developed in the Kornegay laboratory. Current research focus is on preclinical drug trials, including gene therapy (dystrophin gene replacement) via adeno-associated viral vector delivery; utilzing gene editing techniques such as CRISPR/Cas9 and TALENs for treatments of genetic disease; characterization of genetic modifiers via whole-genome next generation sequencing (discovery approach); and evaluation of muscle metabolism in dystrophin deficiency.",Associate Professor,Veterinary Integrative Biosciences,https://scholars.library.tamu.edu/vivo/display/nc223f624
Susan,Bloomfield,Professor,"My research interests focus on the integrative physiology of bone, with specific reference to adaptations to disuse, microgravity, and caloric deficiency.",Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/nc2a60db1
Roderic,Pettigrew,Dean,,Professor||Dean,School of Engineering Medicine||School of Medicine,https://scholars.library.tamu.edu/vivo/display/nc4d62617
Larry,Bellinger,"Regents Professor, Associate Dean for Research and Graduate Studies","Dr. Bellinger is a world renowned expert on the role of the dorsomedial hypothalamic nucleus in regulating ingestive behavior and body weight. Most recently he has used his knowledge of feeding behavior to develop an NIH-funded R01 animal model to study temporomandibular joint, myofacial and tooth nociception. These studies have led to a greater understanding of how gonadal hormones affect nociception. These studies have led to a greater understanding of how gonadal hormones affect nociception both peripherally and centrally.
Dr. Bellinger has been Principal Investigator or Co-investigator on 20 extramural NIH, NSF or company grants and many in-house grants. These projects have produced 161 peer-reviewed research publications and 224 abstracts. Dr. Bellinger's publications have appeared in American Journal of Physiology; Archives in Oral Biology; Arthritis Rheumatism; Brain Research Review; BMC Neuorology; European Journal of Pain; Hormone and Metabolic Research; International Journal of Oral and Maxillofacial Surgery; Journal of Cellular Physiology; Journal of Dental Research; Journal of Neuroscience; Journal of Nutrition; Journal of Oral Maxillofacial Surgery; Life Science; Neuroendocrinology; Neuroscience; Osteoarthritis and Cartilage; Peptides; Pharmacology, Biochemistry and Behavior; Physiology and Behavior; Journal of Cellular Physiology; Journal of Neuroscience; Proceedings of the Society for Experimental Biology and Medicine and many other journals. Dr. Bellinger's work has been well accepted and cited over 4,500 times with an h-index of 34 and h-110 of 106. He has been asked by 35 different journals, including Nature and Science, to review manuscripts and has reviewed NIH and NSF grants. He has been interviewed by Science magazine several times.",Associate Dean for Research and Graduate Studies||Regents Professor,School of Dentistry||Biomedical Sciences,https://scholars.library.tamu.edu/vivo/display/nc540dc8a
Ashley,Saunders,Professor and Assistant Department Head,"I am a Veterinary Cardiologist with research interests primarily focused on congenital heart disease, interventional cardiology, advanced imaging, 3D modeling, heart failure management, biomarkers, and innovative teaching.",Associate Professor and Assistant Department Head,Small Animal Clinical Sciences,https://scholars.library.tamu.edu/vivo/display/nc64dcd64
Paul,Lindahl,Professor,"One of our two current research areas involves iron metabolism in mitochondria. The iron imported into these organelles is assembled into iron-sulfur clusters and heme prosthetic groups. Some of these centers are exported into the cytosol, while others are installed into mitochondrial apo-proteins. All of these processes are regulated in healthy cells, but various genetic mutations giving rise to diseases can cause iron to accumulate (e.g. Friedreich's ataxia) or become depleted (e.g. Sideroblastic anemia). We have developed a biophysical approach involving Mossbauer, electron paramagnetic resonance, and electronic absorption spectroscopy, to study the entire iron content of intact mitochondria in healthy and genetically altered cells. This Systems Biology approach allows us to characterize the ""iron-ome"" of mitochondria at an unprecedented level of detail. We are also using analytical tools (e.g. liquid chromatography) to identify complexes that are involved in ""trafficking"" iron into and out of the organelle.
Our other research area involves mathematical modeling of cellular self-replication on the mechanistic biochemical level. We collaborate on this multidisciplinary NSF-sponsored project with a mathematician at the University of Houston (Professor Jeffrey Morgan). We have developed a modeling framework that facilitates such modeling efforts, and have designed a number of very simple and symbolic in silico cells that exhibit self-replicative behavior. Our minimal in silico cell model includes just 5 components and 5 reactions. A second generation model includes a more realistic mechanism of mitotic regulation. One novel aspect of our approach is that cellular concentration dynamics impact (and are impacted by) cellular geometry. By minimizing membrane bending energies, we are now calculating cell geometry during growth and division. Our results suggest that the ""pinching"" observed in real cells is enforced by cytoskeletal structures.",Professor,Chemistry,https://scholars.library.tamu.edu/vivo/display/nc9ce621b
Reza,Tafreshi,Professor,,Professor,Mechanical Engineering (Qatar),https://scholars.library.tamu.edu/vivo/display/ncbaa347d
Cristine,Heaps,Dr.,,Associate Professor and Associate Department Head,School of Veterinary Medicine and Biomedical Sciences,https://scholars.library.tamu.edu/vivo/display/ncbe2c8d8
Christopher,Woodman,Associate Professor,My research focuses on the interactive effects of aging and exercise training on skeletal muscle vascular beds.,Associate Professor,Kinesiology and Sport Management,https://scholars.library.tamu.edu/vivo/display/ncffb2181
Fen,Wang,Professor,"The laboratory focuses on understanding the molecular basis of cell signaling, and how aberrant cell signaling leads to birth defects and causes cancers. Using in vitro cell culture systems and in vivo mouse models, we study how the fibroblast growth factor (FGF) activates its receptor (FF) tyrosine kinase, and how the activated FF transmits the signals to downstream targets and regulates proliferation, differentiation, homeostasis, and function of the cells, as well as in organogenesis and development, including prostate and cardiovascular system development. The laboratory also employs molecular biology, cell biology, and mouse genetic technologies to study how aberrant FGF signals promote tumor initiation, progression, and metastasis. In addition, how environmental factors contribute to tumorigenesis and congenital birth defects by modulating FGF signal intensity and specificity is also under the scope of our research interests.",Professor,Institute of Biosciences and Technology,https://scholars.library.tamu.edu/vivo/display/nd5ef47ba
Yun,Huang,Associate Professor,"Dr. Huang is currently an Assistant Professor at the Center for Epigenetics and Disease Prevention, Institute of Biosciences & Technology, Texas A&M University. Her long-term goal is to elucidate the molecular basis of epigenetic changes in the human genome and to develop novel therapies by targeting aberrant DNA methylation and demethylation associated with human diseases, including cancer, immunoinflammatory and cardiovascular diseases.
Dr. Huang's laboratory is focused on elucidating the physiological and pathophysiological functions of TET2 protein and its 5-methylcytosine oxidation products (5hmC, 5fC and 5caC) in cancer and development (Nature Genet 2014; Trends in Genetics 2014).",Associate Professor,Institute of Biosciences and Technology,https://scholars.library.tamu.edu/vivo/display/nd7ed0926
Karen,Mansell,Clinical Professor,Comparative pathology with particular interest in dermatopathology. The effects of systemic disease on skin. The use of immunohistochemistry in neoplastic and inflammatory skin disease.,Clinical Professor,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/nd885c362
Sarah,Hamer,Professor,,Professor,Veterinary Integrative Biosciences,https://scholars.library.tamu.edu/vivo/display/ndc2c4e3e
Utpal,Bhalala,Clinical Associate Professor,,Clinical Associate Professor,School of Medicine,https://scholars.library.tamu.edu/vivo/display/ndcfddb61
Raquel,Rech,Clinical Associate Professor,Diagnostic and comparative pathology with emphasis in Neuropathology; Pathogenesis of infectious diseases and toxic plants in food animals and horses.,Clinical Associate Professor,Veterinary Pathobiology,https://scholars.library.tamu.edu/vivo/display/ne4a280f0
Jeffery,Tomberlin,Professor,"My areas of interest and expertise are the ecology and biology of flies associated with decomposing matter. Primarily, my research falls into two categories, 1) determine proper methods for suppressing fly populations associated with animal waste on confined animal facilities, 2) understanding the biology of insects that colonize human remains in order to assist law enforcement personnel in estimating the time of colonization of a corpse in order to provide a minimum postmortem interval.",Associate Professor,Entomology,https://scholars.library.tamu.edu/vivo/display/ne8fb4d5b
Christopher,Quick,Professor,My cardiovascular research focuses on interstitial fluid balance; pulsatile hemodynamics; coordination of adaptation in vascular networks. Since 2016 I have focused on developing research education programs based on the Research-Intensive Community model developed with Dr. Sarah Gatson and students.,Professor,Veterinary Physiology and Pharmacology,https://scholars.library.tamu.edu/vivo/display/neb80aca8
Steven,Woltering,Associate Professor,"My interest, broadly put, is to better understand the role of self-regulation in our behavior and apply this to the field of education. Self-regulation refers to the ability to control your attention and emotions and this capacity is considered crucial for developing a cognitive and emotional competence.",Associate Professor,Educational Psychology,https://scholars.library.tamu.edu/vivo/display/nee2a887b
Paul,Hardin,Distinguished Professor,"A diverse array of organisms including prokaryotic and eukaryotic microbes, plants, and animals display daily rhythms in physiology, metabolism and/or behavior. These rhythms are not passively driven by environmental cycles of light and temperature, but are actively controlled by endogenous circadian clocks that are set by environmental cycles, keep time in the absence of environmental cues, and activate overt physiological, metabolic and behavioral rhythms at the appropriate time of day. This remarkable conservation of circadian clock function through evolution suggests that maintaining synchrony with the environment is of fundamental importance. Our understanding of the circadian clock is particularly important for human health and well-being. The clearest examples of circadian clock dysfunction are those that result in abnormal sleep-wake cycles, but clock disturbances are also associated with other ailments including epilepsy, cerebrovascular disease, depression, and seasonal affective disorder. The realization that disorders of the sleep-wake cycle such as Familial Advanced Sleep Phase Syndrome can result from alterations in clock gene function underscores the clinical importance of understanding the molecular organization of the circadian system.
Work in my laboratory focuses on defining the molecular mechanisms that drive circadian clock function in the fruit fly, Drosophila melanogaster. We previously found that the core timekeeping mechanism is based on core and interlocked transcriptional feedback loops. Our studies currently focus on (1) defining post-translational regulatory mechanisms that operate in the core loop to set the 24 hour period, (2) determining whether interlocked loops are important for circadian timekeeping and/or output, (3) understanding how circadian oscillator cells are determined during development, and (4) defining mechanisms that control rhythms in olfactory and gustatory physiology and behavior.",Distinguished Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nf27056c4
Jay,Maddock,Professor,My research focuses on social ecological approaches to increasing physical activity and the effect of spending time in nature on human health.,Professor||Faculty Fellow,Center for Health Systems and Design||Environmental and Occupational Health,https://scholars.library.tamu.edu/vivo/display/nf33a34f7
Richard,Gomer,Distinguished Professor,"Our laboratory is working on three areas of biomedicine, trying to move observations from basic research into the clinic. First, we are studying how the sizes of tissues and tumors are regulated, and how this can be manipulated for therapeutic purposes. As a model system, we are using the simple eukaryote Dictyostelium discoideum, which allows us to combine techniques such as biochemistry, genetics, computer modeling, and cell biology to study tissue size regulation. We have found that a secreted protein as well as the unusual molecule polyphosphate are signals in negative feedback loops that inhibit Dictyostelium cell proliferation, and we are studying the signal transduction pathway to understand similar mechanisms in humans.
Second, we are studying how some secreted proteins can make cells move away from the source of the signal. We found such a signal (called a chemorepellent) in Dictyostelium, and then found a similar signal in humans. We are working to understand the signal transduction pathway for both. The human signal repels neutrophils, and we found that this can be used therapeutically in mouse models of neutrophil-driven diseases such as rheumatoid arthritis and acute respiratory distress syndrome.
Third, we have found that a human blood protein called Serum Amyloid P (SAP) regulates a key step in the formation of scar tissue as well as the formation of the scar-like lesions in fibrosing diseases such as congestive heart failure and pulmonary fibrosis. We are studying this mechanism, and a biotech company (Promedior, now sold to Roche) we co-founded is testing SAP as a therapy for fibrosis in patients in a Phase 3 trials.",Distinguished Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nf41f3898
Randall,Davis,Regents Professor,"Randall William Davis is an educator and researcher who studies the physiology and behavioral ecology of marine mammals and other aquatic vertebrates. His physiological research focuses on adaptations of marine mammals for deep, prolonged diving. Davis has continually emphasized the importance of studying aquatic animals in their natural environment and has spent many years developing animal-borne instruments that record video and monitor three-dimensional movements, swimming performance and environmental variables to better understand their behavior and ecology. His academic endeavors and 100 research expeditions have taken him to 65 countries and territories on seven continents and all of the world's oceans.
https://en.wikipedia.org/wiki/Randall_William_Davis",Regents Professor||Regents Professor,"Rangeland, Wildlife and Fisheries Management||Wildlife and Fisheries Sciences||Marine Biology",https://scholars.library.tamu.edu/vivo/display/nf5158696
Jerome,Menet,Associate Professor,"Most organisms from bacteria to humans exhibit 24-hours rhythms in their biochemistry, physiology and behavior. Best exemplified by the sleep/wake cycle, these rhythms are remarkably widespread and include in humans hormonal (e.g., melatonin, insulin, cortisol), metabolic (e.g., glucose, cholesterol), physiological and behavioral oscillations. In fact, most biological functions are rhythmic and are set to perform optimally at the most appropriate time of the day. For example, the human digestion process performs better during the day when we are supposed to eat.
These circadian rhythms are generated by ""molecular clocks"", which consist of a few ""clock genes"" interacting in feedback loops, and which drive the rhythmic expression of a large number of genes, i.e. ~10% of the transcriptome in any tissues. This wide impact of clock genes in regulating gene expression is underscored by the surprisingly large number of pathologies developed by clock-deficient mice. In addition to being arrhythmic, these mice indeed develop pathologies as diverse as mania-like behaviors, learning and memory defects, depression, drug addiction, insomnia, metabolic diseases, arthropathy, hematopoiesis defects and cancers.
Research in our lab aims at characterizing how circadian clocks and clock genes regulate gene expression to provide insights into how and why clock dysfuntion leads to a wide spectra of pathologies. To this end, we are using a wide-range of molecular and biochemical techniques to investigate the circadian clock function at the genome-wide level (e.g., next-generation sequencing). We are currently extending some of our recent results and focus on 1) how clock genes rhythmically regulate chromatin environment and 2) the mechanisms involved in rhythmic post-transcriptional regulation of gene expression.",Associate Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nf680fb91
Jiang,Chang,Professor,"Heart failure (impaired ventricular pump function) is an eventual outcome for diverse cardiovascular disorders and the leading cause of combined morbidity and mortality in the United States and other developed industrial nations. The focus of my lab is to understand the molecular and cellular mechanisms that initiate and mediate the pathogenesis of maladaptive cardiac remodeling, such as cardiac hypertrophy and fibrosis as result of various pathological scenarios such as myocardial infarction, hypertension, obesity, diabetes, aging and post-traumatic stress disorder. The overall approach consists of generation and analysis of clinically-relevant genetic mouse models including a tool mouse enabling tracking endogenous cardiac exosomes, and conduct mechanistic studies using cutting-edge technology. The ultimate goal of our efforts is to provide clinical translation for the prevention and treatment of pathological cardiac remodeling from our mechanistic studies.",Professor,Center for Genomic and Precision Medicine,https://scholars.library.tamu.edu/vivo/display/nf80a9dad
Matthew,Powell-Palm,Assistant Professor,,Assistant Professor,Mechanical Engineering,https://scholars.library.tamu.edu/vivo/display/nfb96e566
Uel,Mcmahan,Professor,"McMahan and his research group provide one of the cornerstones for Texas A&M's new Interdisciplinary Life Sciences Building and its related teaching and research efforts. His work focuses on how the nervous system's synapses form in the embryo and function in the adult in various animal species. It relies on high-resolution imaging, chemical characterization and experimental manipulation of specific macromolecules and organelles, which altogether provide insights unobtainable via any other approach. The findings bear directly on the problems of understanding the molecular basis of human brain diseases and restoring brain function after trauma.",Professor,Biology,https://scholars.library.tamu.edu/vivo/display/nfc3672e7
Darwin,Prockop,Professor,,Professor,Cell Biology and Genetics,https://scholars.library.tamu.edu/vivo/display/nfcfd0990